Lipotes vexillifer (Yangtze River dolphin): 103087259
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Entry
103087259 CDS
T03090
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
lve
Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve00220
Arginine biosynthesis
lve00330
Arginine and proline metabolism
lve01100
Metabolic pathways
lve04020
Calcium signaling pathway
lve04022
cGMP-PKG signaling pathway
lve04066
HIF-1 signaling pathway
lve04071
Sphingolipid signaling pathway
lve04151
PI3K-Akt signaling pathway
lve04370
VEGF signaling pathway
lve04371
Apelin signaling pathway
lve04611
Platelet activation
lve04915
Estrogen signaling pathway
lve04921
Oxytocin signaling pathway
lve04926
Relaxin signaling pathway
lve04931
Insulin resistance
lve04933
AGE-RAGE signaling pathway in diabetic complications
lve05415
Diabetic cardiomyopathy
lve05417
Lipid and atherosclerosis
lve05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
lve00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
103087259 (NOS3)
00330 Arginine and proline metabolism
103087259 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
103087259 (NOS3)
04371 Apelin signaling pathway
103087259 (NOS3)
04066 HIF-1 signaling pathway
103087259 (NOS3)
04020 Calcium signaling pathway
103087259 (NOS3)
04071 Sphingolipid signaling pathway
103087259 (NOS3)
04022 cGMP-PKG signaling pathway
103087259 (NOS3)
04151 PI3K-Akt signaling pathway
103087259 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
103087259 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
103087259 (NOS3)
04921 Oxytocin signaling pathway
103087259 (NOS3)
04926 Relaxin signaling pathway
103087259 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
103087259 (NOS3)
05418 Fluid shear stress and atherosclerosis
103087259 (NOS3)
05415 Diabetic cardiomyopathy
103087259 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
103087259 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
103087259 (NOS3)
Enzymes [BR:
lve01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
103087259 (NOS3)
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Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
DEC-1_N
Motif
Other DBs
NCBI-GeneID:
103087259
NCBI-ProteinID:
XP_007469900
UniProt:
A0A340YEP3
LinkDB
All DBs
Position
Unknown
AA seq
1205 aa
AA seq
DB search
MGNVKSVGQEPGAPCGRGLGLGLGLCGKQGPAAPAPEPSWAPAPAPPPALDHSPAPNSPQ
LTRPPEGPKFPRVKNWEAGSITYDTLCAQSQQDGPCTPRRCLGSLVFPRKLQSRPSQGPP
PPEQLLSQARDFINQYYSSIKRSGSQAHKERLQEVEAEVAATGTYQLRESELVFGAKQAW
RNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRTPGR
GDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCVQHGWTPGNSRFDVLPLLLQTPDE
APELFVLPPELVLEVPLEHPTLEWFSALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYM
STEIGMRDLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIV
DHHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYVLSPAFRYQPD
PWKGSTAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYASETGRAQSYAQQL
GRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYN
SSPRPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYP
HFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQASCETFCVGEDAQA
AAQDIFSPKRSWKRQRYRLSAQAEGLQLLPGLIHVHRRKMFQATVLLVENLQSSKSTRAT
ILVRLDTGSQEGLQYQPGDHIGICPPNRPGLVEALMSRVEDPPPPTESVAVEQLEKGSPG
GPPPGWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPSEQQELETLSQDPR
RYEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRHYSVSSAPSAHPGEIHLTVA
VLAYRTQDGLGPLHYGVCSTWLSQLKTGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGI
APFRGFWQERLHDIESKGLQPAPMTLVFGCRCSQLDHLYREEVQDAQQRGVFGRVLTAFS
REPNSPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATSVLQTVQRILATEGDME
LDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERHMRGAVPWAFDPPGP
DTPGP
NT seq
3618 nt
NT seq
+upstream
nt +downstream
nt
atgggtaacgtgaagagcgtgggccaggagcccggggcgccctgcggccgggggctaggg
ctgggcctcgggctgtgcggcaagcagggcccggccgccccggcgcccgagcccagctgg
gcgccggcccccgcacccccgccagcgctggaccacagcccggcccccaacagcccccag
ctaacccggcctccagaggggcccaagttccctcgcgtgaagaactgggaggcggggagc
atcacctacgacactctgtgtgcgcagtcacagcaggacgggccctgcacccccagacgc
tgcctgggctccctggtgtttccgcggaaactgcagagccgaccctcccagggccctccg
ccccctgagcagctgctgagccaggccagggacttcatcaaccagtactacagctccatc
aagaggagcggctcccaggctcacaaggagcggcttcaggaagtggaagccgaggtggca
gccacgggcacctaccagcttcgtgagagcgagctggtgttcggggccaagcaggcctgg
cgcaacgccccccgctgcgtgggccggatccagtgggggaagctgcaggtgtttgatgcg
cgggattgcagctctgcacaggagatgttcacctacatctgcaaccacatcaagtacgcc
accaaccggggcaacctccgttcggccatcacagtgttcccccagcgcactccgggccgc
ggagacttccgaatctggaacagccaactggtgcgctatgcgggctacaggcagcaggat
ggctccgtgaggggggacccagccaacgtggagatcaccgagctctgtgtccagcacggc
tggaccccaggaaacagccgctttgatgtgctacccctgctgctccagaccccagatgag
gctccagaactctttgttctgccccccgaactggtcctcgaggtgcccctggagcacccg
acgctggagtggttctcggccctgggcctgcgctggtacgccctcccagcagtgtccaat
atgctgctggaaattgggggcctggagttccctgcagcccccttcagcggctggtacatg
agcacggagattggcatgcgggacctgtgtgatccccaccgctacaacatcctggaggac
gtggccgtctgcatggacctggatacccggaccacctcatccctgtggaaagacaaggca
gccgtggaaatcaacctggctgtgctgcacagttaccagctcgccaaagtgaccattgtg
gaccaccacgccgccacggcctccttcatgaagcacctagagaacgagcagaaggccagg
gggggctgccctgccgactgggcctggatcgtgccccccatctcgggcagcctcacccca
gtcttccatcaggagatggtcaactatgtcctgtcccctgctttccgctaccagccagac
ccctggaaggggagcacagccaagggcaccggcatcaccaggaagaagacgtttaaggaa
gtggccaatgcagtgaagatctctgcctcactcatgggcaccgtgatggcgaagcgagtg
aaagctacgattctgtacgcctccgagaccggccgggcccagagctacgcacagcagctg
gggaggctcttccggaaggcctttgaccctcgggtcctgtgcatggatgagtatgacgtg
gtgtccctggagcacgagacactggtgttggtggtgaccagcacctttgggaatggcgat
cccccagagaatggagagagttttgcagcagccctgatggagatgtcgggcccctacaac
agctcccctcggccagaacaacacaagagttacaaaatccgcttcaacagcgtctcctgc
tcagacccgctggtgtcctcctggcggcggaagaggaaggagtccagtaataccgacagc
gcgggggcgctggggaccctcaggttctgtgtgtttgggctgggctcccgggcatacccc
catttctgcgcctttgctcgtgctgtggacacgcggctggaagagctaggaggggagcgg
ctgcttcagctgggccagggcgatgagctgtgcggccaggaggaggccttccgcggctgg
gctcaggctgccttccaggcctcctgtgagacgttctgtgtgggggaggatgcccaggcc
gcggcccaggacatcttcagccccaaacggagctggaaacgccagaggtaccggctgagc
gcccaggccgagggcctccagctgctgccaggcctgatccacgtgcacaggcggaagatg
ttccaggccacagtcctcttggtggaaaacctgcaaagcagcaagtccacccgggccaca
atcctggtgcgcctggacactggaagccaggaggggctccagtaccagccgggggaccac
ataggcatctgcccacccaaccggccggggctcgtggaggcgctgatgagccgcgtggag
gacccgccaccgcccactgagtctgtggcagtggagcagctggagaagggcagcccaggt
ggccctcctcccggctgggtgcgggacccccggctgcccccgtgtacgctgcgccaggct
ctcacctttttcctggacatcacctccccgcccagccctcaacttctccgactgctcagc
accctggctgaagagcccagtgaacagcaagagctcgagaccctcagccaggacccccgg
cgctacgaggagtggaagtggttccgctgccccaccctgctggaggtgctcgagcagttt
ccatctgtggcactgcccgccccgctgcttctcacccagctgcccctgctccagccccgg
cactactcggtcagctcagcgcccagcgcccatccaggagagatccacctcacagtagct
gtgctggcatacaggacccaagatgggctgggtcccctgcactatggagtctgctccacg
tggctgagccaactcaagactggagaccccgtaccctgcttcatcaggggggctccctcc
ttccggctgccgcctgatcccagcttgccctgcatcctcgtgggcccgggcactggcatc
gcccccttccggggattttggcaggagcggctacatgacatcgagagcaaagggctgcag
cctgcccccatgaccttggtgttcggctgccggtgctcccagctcgaccatctctaccgc
gaggaggtgcaggatgcccagcagcgcggggtgtttggccgcgtcctcaccgccttctcc
cgggaacccaacagccctaagacctacgtgcaggacatcctgcggacggagctggctgca
gaggtgcaccgcgtgctgtgcctcgagcggggccacatgtttgtctgcggcgatgtcacc
atggcaaccagcgtcctgcagacggtgcagcgcatcttggcgacagagggcgacatggag
ctggatgaggccggcgacgtcatcggcgtgctgcgggatcagcaacgctatcatgaggac
attttcgggctcacgctgcgcacccaggaagtgacaagccgcatacgcacccagagcttt
tccttgcaggagcggcatatgcggggcgcagtgccctgggcgttcgacccgcccggccca
gacacccctggcccctga
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