Lipotes vexillifer (Yangtze River dolphin): 103088377
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Entry
103088377 CDS
T03090
Symbol
ERN1
Name
(RefSeq) LOW QUALITY PROTEIN: serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
lve
Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve04140
Autophagy - animal
lve04141
Protein processing in endoplasmic reticulum
lve04210
Apoptosis
lve04932
Non-alcoholic fatty liver disease
lve05010
Alzheimer disease
lve05012
Parkinson disease
lve05014
Amyotrophic lateral sclerosis
lve05016
Huntington disease
lve05017
Spinocerebellar ataxia
lve05022
Pathways of neurodegeneration - multiple diseases
lve05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
lve00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
103088377 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
103088377 (ERN1)
09143 Cell growth and death
04210 Apoptosis
103088377 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
103088377 (ERN1)
05012 Parkinson disease
103088377 (ERN1)
05014 Amyotrophic lateral sclerosis
103088377 (ERN1)
05016 Huntington disease
103088377 (ERN1)
05017 Spinocerebellar ataxia
103088377 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
103088377 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
103088377 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
103088377 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lve01001
]
103088377 (ERN1)
Enzymes [BR:
lve01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
103088377 (ERN1)
Protein kinases [BR:
lve01001
]
Serine/threonine kinases: Other
IRE family
103088377 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
103088377
NCBI-ProteinID:
XP_007456867
UniProt:
A0A340X9X4
LinkDB
All DBs
Position
Unknown
AA seq
1251 aa
AA seq
DB search
MHPGSDIWQALCLDHSASLDARRRSLVLFCRRGRDTQGQPEAQAAFGTAYNPAPPATAPP
SPTPARPQAWAPPRPRLLPRPDRKKRRRPSPGRRRTVVAAPPPRPLHARTVPQEPAGPVR
SQGRVLAMPARLQLLLLALLLPSPRVSDREGWGGERRGTGRGPSRERGGGGGSRLRAPGR
RSGGHGRPRRGVRHPGASRASAAVTSSAYPAACSPAQLCVVLAAPRGLQKGPGPWEAAPP
AGPFPPVGANSAWRWPRRKGRKGPPEGFLLKVHRWKAAPQKALQETAGPCLSRCTSIFGS
PSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVPTHVEEPAFLPDPNDGSL
YTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQDIWYVIDLLTGEKQQTLSSA
FADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYAAALPEDDGEYKMSHFVSNG
DGLVVTVDSESGDVLWIQNYASPVVAFYIWQREGLRKVMHINVAVETLRYLTFMSGEVGR
ITKWKYPFPKETEAKSKLMPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTD
GVTIGDKGECVITPSTDLKFDPGLKGKSKLTYLHNYWLLIGHHETPLSASTKMLERFPNN
LPKXXXXPADSEKKSFEEVIDLVDQTSENAPTTVSPDVEEKFAHAPPRPEAPVDSMLKDM
ATIILSTFLLIGWVAFIITYPLSRRQQRQLQHQQFQKELEKIQLLQQQQLPFHPPGDVAA
QDAELLDSCGQYSESSATSSPSTSPRVSNHSLHSSGSTSRAATSPFPEQDDEDEETSMVM
VGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNV
IRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTTSGLAHLHSLNIV
HRDLKPHNILLSMPSAHGRIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSE
DCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGACSLDCLHPEKHEDVIA
RELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQLERG
GRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPEEVRETLGPL
PDGFVRYFTSRFPHLLSHTYRAMELCRRERPFQPYYHEPPEPRPPVTPDAL
NT seq
3756 nt
NT seq
+upstream
nt +downstream
nt
atgcacccaggctcagacatctggcaagctctttgcctcgatcactcagcgtccctagat
gcccgacgcagaagcctggtgctcttctgccgccgcggccgggacactcaaggccagccg
gaggcccaagctgcctttggcaccgcctataaccccgcccctccagcgacagccccgccc
agtccaaccccagcccgcccccaagcctgggccccgccccggccccgcctcctgccccgc
cccgaccggaagaagcgccggcgcccgagtcccggccgccgccgcactgttgtcgcggcg
cccccgccccgtcctctgcacgcccgcaccgtcccccaggagccggccggaccggtcagg
agccagggccgagtcctcgccatgcctgcccgactgcagctgctgctgctggcgttgctg
ctgcccagcccccgggtgagtgaccgggaaggttggggtggggaacggcgcgggacgggc
cggggtccgagccgggagcgcggcggtggcggcggctccaggctccgtgcgcccgggcgg
agaagtggcggccacggccggccccgccgaggcgtccgccacccaggggcctcgcgggcc
agcgcggctgtcacgagcagcgcctacccggccgcgtgctctccggcgcaactttgtgtc
gtcctagcggcacctcggggtctccagaagggcccgggcccttgggaggctgccccacct
gccggacccttcccgccggtgggcgccaactcggcctggcggtggccgcggaggaagggc
agaaagggccctcctgaagggtttttactgaaggtgcaccgctggaaggccgcaccgcag
aaggccctgcaggagacggccggtccctgtctcagccgctgcacctcgatttttggaagc
cccagcactgtgacacttcctgaaaccttgttgtttgtatcaaccctggacggaagtttg
catgccgtcagcaagaggacaggctcaatcaaatggactttgaaagaagatccagtcctc
caggttccaacacacgtggaagagcctgcattcctcccagatcccaacgatggcagcctg
tatacgcttgggggcaagaataatgaaggcctgacgaaacttccctttacgatcccagag
ttggtgcaggcttccccgtgccgaagttcggatggaattctctacatgggtaaaaagcag
gacatctggtacgtcattgacctcctgaccggggagaaacagcagactttgtcatcggcc
tttgcggatagtctctgcccatcaacctctcttctgtatcttgggcgaacagagtacacc
atcaccatgtacgacaccaaaacccgcgagctccggtggaacgccacctacttcgactac
gcagctgcgctgcccgaggacgacggggaatataaaatgtcccactttgtgtccaatggc
gatgggctggtggtgaccgtggacagtgaatctggggacgtcctgtggatccaaaactat
gcttcccccgtggtggctttttacatctggcagcgggagggtctgcggaaggtgatgcac
atcaacgtcgctgtggagaccctgcgctacctgaccttcatgtcgggggaggtggggcgc
atcaccaagtggaagtacccattccccaaggagacggaggccaagagcaagctgatgccc
accctgtatgtggggaaatactctaccagcctctacgcttccccctcaatggtacacgag
ggggtcgccgttgtgccccgaggcagcacccttcctttgctggaaggaccccagaccgac
ggtgtcaccatcggggacaaaggggaatgtgtgatcacacccagcacggacctgaagttc
gaccctgggctcaaagggaagagcaagctcacctacctgcacaactactggctgctcatc
gggcaccatgagaccccactgtctgcatctaccaagatgctggagcgattccccaacaat
ctgcccaaannnnnnnnnnnncctgctgactcagagaaaaagagctttgaggaggttatc
gacctggttgaccagacttcagaaaatgcacctaccacagtttctccagatgtggaagag
aagttcgctcatgccccccccaggcccgaggcccccgtggactccatgctcaaggacatg
gccaccatcatcctgagcaccttcctgctcattggctgggtggccttcatcatcacctac
cccctgagcagacgtcagcagcggcagctccagcaccagcagtttcagaaggaactggag
aagatccagctcctgcaacagcagcagctgcccttccacccacccggagatgtcgcagct
caggacgccgagctcctggactcgtgcggacagtactcggagagctcagccaccagcagc
cccagcacgtcccccagggtctccaaccactcgctccactccagcggctccacctccagg
gctgccaccagccccttcccggagcaggatgacgaggatgaggaaaccagcatggtgatg
gttgggaaaatctcattctgtccgaaggacgtcctgggccatggagccgagggcacaatt
gtgtaccgtggcatgtttgacaaccgcgacgtggccgtcaagaggatcctccccgagtgt
tttagtttcgcagaccgtgaggtccagctgctgcgagaatcagacgagcacccaaacgtg
atccgttacttctgcaccgagagggaccggcagttccagtacatcgccatcgagctgtgc
gcggccaccctgcaggagtacgtggagcagaaagactttgcccaccttggcctggagccc
atcaccttgctgcagcagaccacctcgggcctggcccacctgcactccctcaacattgtt
cacagagacctgaagccacacaacatcctcctctccatgcccagcgcacatggcaggatc
aaggccatgatctccgacttcggcctctgtaagaagctggcagtgggcagacacagcttc
agccgccgctcaggggtgcccggcacagaaggctggatcgccccggagatgctgagcgaa
gactgcaaggagaaccccacctacacggtggacatcttttctgcgggctgcgtcttttac
tacgtgatatctgagggcagccacccttttggcaagtccctgcagcggcaggccaacatc
ctcctgggcgcctgcagcctggactgcctgcaccctgagaagcacgaagacgttattgct
cgggagttaatagagaagatgattgcaatggatcctcagaagcgcccgtcagcgaagcat
gtgctgaaacacccgtttttctggagcctagaaaagcagctccagttcttccaggacgtg
agtgaccggatagagaaggagtccctagacggcccgatagtgaagcagctggagcgcggc
gggcgggctgtggtgaagatggactggagggagaacatcactgtccccctccagacagat
ctgcgtaaattcagaacctataaaggcggctctgtccgagacctcctccgggccatgaga
aataagaagcaccactaccgggagctgcccgaggaggtgcgggagacgctgggccccctt
cccgacggcttcgtgcgctacttcacgtcgcgcttcccccacctcctctcccacacctac
cgcgccatggagctgtgccgccgcgagaggcccttccagccctactaccacgagcccccc
gagccccggcccccggtgactccagacgccctctga
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