KEGG   Lipotes vexillifer (Yangtze River dolphin): 103090575
Entry
103090575         CDS       T03090                                 
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
  KO
K04857  voltage-dependent calcium channel L type alpha-1S
Organism
lve  Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve04010  MAPK signaling pathway
lve04020  Calcium signaling pathway
lve04022  cGMP-PKG signaling pathway
lve04024  cAMP signaling pathway
lve04260  Cardiac muscle contraction
lve04261  Adrenergic signaling in cardiomyocytes
lve04270  Vascular smooth muscle contraction
lve04723  Retrograde endocannabinoid signaling
lve04725  Cholinergic synapse
lve04726  Serotonergic synapse
lve04727  GABAergic synapse
lve04911  Insulin secretion
lve04912  GnRH signaling pathway
lve04921  Oxytocin signaling pathway
lve04924  Renin secretion
lve04925  Aldosterone synthesis and secretion
lve04927  Cortisol synthesis and secretion
lve04929  GnRH secretion
lve04934  Cushing syndrome
lve04935  Growth hormone synthesis, secretion and action
lve05010  Alzheimer disease
lve05020  Prion disease
lve05022  Pathways of neurodegeneration - multiple diseases
lve05207  Chemical carcinogenesis - receptor activation
lve05410  Hypertrophic cardiomyopathy
lve05412  Arrhythmogenic right ventricular cardiomyopathy
lve05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:lve00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103090575 (CACNA1S)
   04020 Calcium signaling pathway
    103090575 (CACNA1S)
   04024 cAMP signaling pathway
    103090575 (CACNA1S)
   04022 cGMP-PKG signaling pathway
    103090575 (CACNA1S)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    103090575 (CACNA1S)
   04929 GnRH secretion
    103090575 (CACNA1S)
   04912 GnRH signaling pathway
    103090575 (CACNA1S)
   04921 Oxytocin signaling pathway
    103090575 (CACNA1S)
   04935 Growth hormone synthesis, secretion and action
    103090575 (CACNA1S)
   04924 Renin secretion
    103090575 (CACNA1S)
   04925 Aldosterone synthesis and secretion
    103090575 (CACNA1S)
   04927 Cortisol synthesis and secretion
    103090575 (CACNA1S)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    103090575 (CACNA1S)
   04261 Adrenergic signaling in cardiomyocytes
    103090575 (CACNA1S)
   04270 Vascular smooth muscle contraction
    103090575 (CACNA1S)
  09156 Nervous system
   04727 GABAergic synapse
    103090575 (CACNA1S)
   04725 Cholinergic synapse
    103090575 (CACNA1S)
   04726 Serotonergic synapse
    103090575 (CACNA1S)
   04723 Retrograde endocannabinoid signaling
    103090575 (CACNA1S)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    103090575 (CACNA1S)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103090575 (CACNA1S)
   05020 Prion disease
    103090575 (CACNA1S)
   05022 Pathways of neurodegeneration - multiple diseases
    103090575 (CACNA1S)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    103090575 (CACNA1S)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    103090575 (CACNA1S)
   05414 Dilated cardiomyopathy
    103090575 (CACNA1S)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    103090575 (CACNA1S)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:lve04040]
    103090575 (CACNA1S)
Ion channels [BR:lve04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   103090575 (CACNA1S)
SSDB
Motif
Pfam: Ion_trans Ca_chan_IQ GPHH PKD_channel CAC1F_C
Other DBs
NCBI-GeneID: 103090575
NCBI-ProteinID: XP_007456198
UniProt: A0A340X3Q5
LinkDB
Position
Unknown
AA seq 1868 aa
MEPSSTQDEGLRRKQTKKPVPEVLPRPPRALFCLTLQNPVRRACISIVEWKPFETIILLT
IFANCVALAAYLPMPEDDSSALNLGLEKLELLFLIVFSIEAAMKIIAYGLLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNVIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSVFKAMQPLFRIALLVLFMAIIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRRCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLD
EDLRGYLSWITQGEVMDVDDLREGKLALDEGGSDTESLYEIAGLNKVIQFIRHWRRWNRV
FRWKCHDAVKSRVFYWLVILIVALNTLSIASEHHHQPLWLTHLQDVASRVLLALFTVEML
MKMCGLGLHQYFMSIFNRFDCFVVCCGLLEILLVESGAAAPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSIHCIASLLLLLSLFVVIFALLGMQLFGGRYDFEDTVVRRSNFDNF
PQALITVFQVLTAEDWNSVMYDGIMAYGGPTYPGVLVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERRRRKMSRGLPDKSEEEKSMVAKKLEQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPISPRPRPLAELQLKEKAVPIPEASAFF
VLSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRTESVRNQILGYFDIVFT
SIFTVEIVLKMTTYGAFLHKGSFCRNHFNILDLLVVAVSLISMGLESSTISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDL
SKMTEEECRGHYYVYKDGDPTQMELRPRQWTHNSFHFDNVLSAMMSLFTVSTFEGWPELL
YRAMDSQEEDGGPAHNRRPEVAVFFIAYIILVALFMMNIFVGFVIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLKCYIPKNPCQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHY
NQSEQMDHISDILNVAFTTIFTVEMVLKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGSCGNVDPDESARISSAFFRLFRVLRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGQLCDPESDYAPGEERTCGTDFAYYYFVSFYTLCAFLVINLFVAVV
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMRRQEEYYGYRPKKDTVQIQAGLR
TLEEEAAPEIRRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDSFLERSNSLPP
HMANQRPLQFTEIEMQELESPVFLEDFPQHPSTNPLARANTNNANANVAGGNSNHGNSPA
FSSVHSEGELPGETETPATRGGASGRPQRTLGPHSKSHGERLQGRLPRRVIPRAQAPAAP
CQLVGTQSLVPEERSPTPGSLPEEAPPKDGTPVCLAPATALLIREALVRGGLDTLAADAK
FVMATSHTLVEACQMELQEVEVAAAELLKGRETLEGVASARGRWSLGSSLGSLDQHQGSQ
ETLIPRRL
NT seq 5607 nt   +upstreamnt  +downstreamnt
atggagccgtcctcgacccaggatgagggcctgaggaggaagcagaccaagaagcctgtt
cccgaggtcctgcccaggccgccgcgggctttgttctgcttgactctccagaaccccgtg
aggagggcctgcatcagcatcgtggaatggaaacccttcgagaccatcatcttactcacc
atctttgccaactgtgtggccttggccgcgtacctgcccatgccggaggacgacagcagc
gctctgaacctcggcctggagaagctggagctcttgttcctcatcgtcttctccatcgag
gccgccatgaagatcatcgcctacggcctcctgttccaccaggacgcctacctgcgcagc
ggctggaacgtgctggactttatcatcgtcttcctgggggtcttcaccgtgattctggag
caggtcaacgtcatccagagcaacacagccccgatgagcagcaaaggcgccggcttggac
gtcaaggctctgagggccttccgcgtgctcagaccgctccggctggtgtccggggtgccc
agcctgcaggtggtcctcaactccgtcttcaaggccatgcagcccctgttccgcatcgcc
ctgcttgtgctcttcatggccatcatctacgccatcatcgggctggagctcttcaagggc
aagatgcacaagacctgttacttcatcgggacggacatcgtggccacggtggagaacgag
aagccgtcgccctgtgcccggacgggttcagggcgccgctgcaccatcaacggcagcgag
tgccggggcggctggccaggccccaaccacggcatcacccacttcgacaacttcggcttc
tccatgctcaccgtgtaccagtgcatcaccatggagggctggaccgacgtcctctactgg
gtcaacgatgccattgggaacgagtggccctggatctactttgtcaccctgatcctgctg
ggttccttcttcatcctcaacttggtgctgggcgtcctgagcggggaattcaccaaggag
cgggagaaagccaagtccaggggaaccttccagaagctgcgcgagaagcagcagctggat
gaggacctccggggctacttgagctggatcacgcagggcgaggtcatggatgtggacgac
ttgagagaagggaagctggctttggatgaaggtggctctgacacagagagcctgtatgaa
atcgcaggcttgaacaaagtcatccagtttatccgacactggaggcggtggaaccgcgtc
ttccgctggaagtgccacgacgcggtgaagtccagggtcttctactggctggtcatcctg
atcgtcgccctcaacaccctgtcgatcgcctcggaacaccaccaccagcctctctggttg
acccacctgcaagacgtcgccagccgggtgctgctggccctgttcaccgtggagatgctc
atgaagatgtgcgggctgggcctacatcagtacttcatgtccatcttcaaccgcttcgac
tgctttgtggtgtgctgtggcctcctggagatcctgctggtggagtcgggggccgcggca
cccctcggcatctccgtgctgcgctgcatccgcctcctcaggattttcaagatcaccaag
tactggacgtccctgagcaacctggtggcctcgctgctgaactccatccactgcatcgcg
tccctgctgctgctgctgtccctgttcgtcgtcatcttcgccctcctgggcatgcagctc
ttcgggggcaggtacgactttgaggacacggtggtgcggcgcagcaacttcgacaacttc
ccgcaggccctcatcaccgtcttccaggtgctgacagctgaggactggaactctgtgatg
tacgacgggatcatggcctacggcggcccgacctaccccggggtgctcgtctgcatctat
ttcatcattctgttcgtctgcggcaactacatactgctcaacgtcttcctggccatcgcg
gtagacaacctggcggaggcggagagcctgacgtcggcccagaaggccaaggccgaggag
cggaggcgcaggaagatgtccagggggcttccagacaagtcagaggaagagaagtcgatg
gtggccaagaagctggagcagaaacccaagggggagggtatccccaccacggccaagctg
aagatcgatgagtttgaatccaatgtcaatgaggtgaaggacccctacccgtcagccgac
ttcccaggagatgatgaggaagacgaacccgagatcccgataagcccccgaccccgcccg
ctggccgagctgcagctgaaggagaaggcggtgcccatcccagaagccagcgccttcttt
gtcctcagccccaccaataagatccgcgtcctgtgccaccgcatcgtcaacgccacctgg
ttcaccaacttcatcctgctcttcatcctgctgagcagcgccgcgctggctgccgaggac
cccatccggactgagtccgtgaggaaccagatccttgggtattttgacatcgtgttcacc
tctatcttcactgtggagattgtcctcaagatgaccacctacggggccttcctgcacaag
ggctccttctgccgtaatcacttcaacatcctggacctgctggtggtggccgtgtccctc
atctccatgggactcgagtctagcaccatctccgtggtgaaaatcctgagggtgctgagg
gtactccgaccgctccgggccatcaacagagccaaagggctgaagcacgtggtgcagtgt
gtgttcgtggccatccgcaccatcgggaacatcgtcctggtcaccaccctcctgcagttc
atgttcgcctgcatcggcgtccagctcttcaaggggaaattcttcagctgcaatgacttg
tccaagatgacagaggaggagtgcaggggccactactacgtgtacaaggatggggacccc
acgcagatggagctgcgcccccgccagtggacgcacaacagcttccacttcgacaacgtg
ctctcggccatgatgtcactcttcacggtgtccaccttcgaggggtggcctgagctgctg
tacagggccatggactctcaggaggaggacgggggccccgcgcacaacaggcgcccggag
gtggccgtcttcttcatcgcctacatcatcctcgtcgccctattcatgatgaacatcttc
gtgggcttcgtcatcgtcaccttccaggagcagggggagaccgagtacaagaactgcgag
ctggacaagaaccagcgccagtgcgtgcagtacgccctgaaggcccgccccctgaagtgc
tatatccccaaaaacccgtgccagtaccaggtgtggtacgtcgtcacctcctcctacttc
gagtacctaatgttcgccctcatcatgctcaacaccatctgcctgggcatgcagcactac
aaccagtcggagcagatggaccacatctcagacatcctcaacgtggccttcaccaccatc
ttcacggtggagatggtcctcaagctcatggcgttcaaggccaggggctattttggggac
ccctggaatgtgtttgacttcctgattgtcatcggcagcatcatcgacgtcatcctcagt
gagattgatactttcctggcctccagcgggggactgtattgcctgggtggcagctgcggg
aacgttgaccccgacgagagcgcccgcatctccagcgccttcttccgcctgttccgcgtc
ctgaggctgatcaagctgctgagccgcgcggagggcgtgcgcacgctgctctggaccttc
atcaagtcctttcaggccctgccctacgtggctctgctcatcgtcatgctcttctttatc
tacgccgtcatcggcatgcagatgttcgggaagattgccctggtggacgggacccagatc
aaccggaacaacaacttccagaccttcccccaggctgtgcttttgctgttcaggtgtgcc
acgggtgaggcgtggcaggagatcctgctggcctgcagctatggccagctgtgcgacccc
gagtcggactacgcgccgggggaggagcgcacctgtggcaccgacttcgcctactactac
tttgtcagcttctacacgctttgtgccttcctggtcatcaacctctttgtggctgtcgtc
atggacaactttgactacctcacacgggactggtccatcctgggccctcatcacctggac
gagttcaaggccatctgggcagagtatgacccagaggctaagggcagaatcaaacacctg
gacgtggtgaccctgctgagaaggatccagccccctctgggctttgggaagttctgccca
caccgggtagcatgtaagcggctggtgggcatgaacatgcccctgaacagcgacggcaca
gtcaccttcaacgccactctcttcgccctggtccgcacggcgctcaagatcaagacggaa
ggtaacttcgaacaggccaatgaggagctgcgggccatcatcaagaagatctggaagagg
accagcatgaagctcctggaccaggtcatccctcccataggagatgacgaggtgacggtg
ggaaagttctacgccacgtttctcatccaggagcacttccggaagttcatgaggcgccag
gaggaatattatgggtaccggcccaagaaggacaccgtgcagatccaggccggactgcgg
acccttgaggaagaggcagcccctgagatccgccgcaccatctcgggagacctgacggcc
gaggaagagctggagagagccatggtggaggccgcgatggaggaagggatattccggagg
accggaggcctgtttggccaggtggacagcttcctggaaaggtccaactccctgcctcca
cacatggccaaccagagacccctccagtttactgaaatagagatgcaggagctggagtcg
cccgtcttcttggaggacttccctcagcatccaagcaccaaccctcttgcccgtgccaac
accaacaatgccaacgccaacgttgccggtggcaacagcaaccatggcaacagcccggca
ttttccagcgtccactctgaaggggagctcccaggggagacagagacgcctgccaccaga
ggaggagcctccggccggccccagaggaccctgggaccccacagcaagtcccatggggag
aggctgcagggacggctgccccggagggtgatacccagagctcaggcacctgccgccccc
tgccagcttgtggggacacagtctctggtgcccgaggagaggagccccaccccagggtcc
ctgcctgaggaagcgccccccaaggatggtacccctgtgtgcctggccccagccacggcc
ctgctgatccgagaggctctggttcgagggggcctggacaccttggcggctgatgctaag
ttcgtcatggcaacgagccacaccctggtggaagcctgccagatggaactgcaggaagtg
gaggtggcagccgctgagcttctgaagggacgagagaccctggagggtgtggccagtgcc
cgggggcgttggagcctcgggtcctccctgggaagcctcgaccagcatcagggctcccag
gagaccctcattccccgcaggctgtga

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