Leptonychotes weddellii (Weddell seal): 102725836
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Entry
102725836 CDS
T08708
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X3
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
lww
Leptonychotes weddellii (Weddell seal)
Pathway
lww00790
Folate biosynthesis
lww01100
Metabolic pathways
lww01240
Biosynthesis of cofactors
lww01523
Antifolate resistance
lww04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
lww00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
102725836 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
102725836 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102725836 (FPGS)
Enzymes [BR:
lww01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
102725836 (FPGS)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
102725836
NCBI-ProteinID:
XP_006744208
UniProt:
A0A2U3YKV0
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All DBs
Position
Unknown
AA seq
588 aa
AA seq
DB search
MSQARCHLRAALFLAAVSPRGATTGVTARRGLSAWPAPQEPGMEYQDAVRTLNTLQTNAG
YLEQVKRQRGDPQTQLEAMKLYLARSGLQVEDLDQLNIIHVTGTKGKGSTCAFTERVLRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKHFWHLYHRLEETKDSSSCVSMPAYFR
FLTLMAFHIFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEEI
AWQKGGIFKRGVPAFTVLQPDGPLAVLRDRAQQISCPLYLCPPLEALEEGGPPLTLGLDG
EHQRFNAALALQLARCWLQQKGHQGLGELKVSRPSVLRQMPLAPVFQPTPHMRHGLRDTE
WLGRTQVLRRGPLTWYLDGAHTTSSVQACVRWFHQALLRGHRPGRGPEVRILLFNSTGDR
DSAALLKLLQPCQFDYAVFCPNLTEVSSAGNADQQNFMVTLDQVLLRCLAHQQYWSHLAE
AQASPDLWSPPSPEPGEPTSSLLASHPPRTHSTSSLVFSCISHALQWISQGRDPVFQPPS
PPQGLLAHPVAGSGAGVLREAAAIHVLVTGSLHLVGGVLKLLEPALSQ
NT seq
1767 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcaggcacgctgccacctgcgtgccgctctcttcctggcagcagtttctccgcgc
ggtgcaacgaccggggtcacggcgcggcgagggttgagcgcgtggcccgcgccgcaggag
cccggcatggagtatcaggatgctgtgcgcacactgaacaccctgcagaccaatgctggc
tacctggagcaggtaaagcgccagcggggtgaccctcagacacagctggaagcgatgaag
ctgtacttggcccggagtgggctgcaggtggaagacttggaccagctgaacatcattcac
gtcactgggaccaaggggaagggttccacgtgtgccttcaccgaacgtgttctccgcagc
tatggcctgaagacgggattctttagctctccccacctggtgcaggtgcgggagcggatc
cgcatcaacgggcagcccataagccccgagctcttcaccaagcacttttggcacctctac
caccggctggaggagaccaaggacagcagcagctgcgtctccatgcctgcctacttccgc
ttcctcacactcatggccttccacatcttcctccaagagaaggtggacctggcagtggtg
gaagtgggcattggtggcgcttacgactgcaccaacatcatcaggaagcctgtggtgtgt
ggcgtctcctctcttggcatcgaccacaccagccttctgggggacacagtggaggagatc
gcatggcagaaagggggcatcttcaagcgtggcgtccctgccttcacggtgctccagcct
gacggtcccctggcggtgctgcgggaccgtgcccagcagatctcctgtcctctctacctg
tgcccgccactggaagccctggaggaaggggggccgccgctgaccctgggcctggatgga
gagcaccagcggttcaacgccgccttggctttgcagctggctcgctgctggctgcagcaa
aagggccaccagggcctcggggagctgaaggtgtctcggcccagcgtcttgcggcagatg
cccctggcacccgtgttccagcccacgccccacatgcggcatgggcttcgggacacggag
tggctgggccggacgcaggtgctgcggcgcgggcccctcacctggtacctggacggcgcg
cacaccaccagcagcgtgcaggcctgcgtgcgctggttccaccaggcgctgctccgaggc
cacaggcctggccgcggccctgaggtacgcatcttgctcttcaactccaccggggaccgg
gattccgcggccctgctgaagctgctgcagccctgtcagtttgactatgctgttttctgc
cctaacctgacagaggtgtcgtctgctggcaacgcagaccagcagaacttcatggtgacc
ctggaccaggtgctgctccgttgcctcgctcaccaacagtactggagccacctggccgag
gcgcaggccagcccagacctctggagcccccccagcccggagcctggtgagcccacatcc
tcgctgctggcttcccacccaccccgcacccatagcaccagctccctcgtcttcagctgc
atctcgcacgccctgcagtggatcagccaaggccgggaccctgtctttcagccacccagt
cccccacagggcctccttgcccaccctgtggcaggcagcggggccggcgtgctccgcgag
gctgccgccatccatgtacttgtcacgggcagcttgcacctggtgggcggcgtcctgaag
ctgctggagcctgccctgtcccagtag
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