Leptonychotes weddellii (Weddell seal): 102726305
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Entry
102726305 CDS
T08708
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
lww
Leptonychotes weddellii (Weddell seal)
Pathway
lww00260
Glycine, serine and threonine metabolism
lww00630
Glyoxylate and dicarboxylate metabolism
lww00670
One carbon pool by folate
lww01100
Metabolic pathways
lww01200
Carbon metabolism
lww01230
Biosynthesis of amino acids
lww01240
Biosynthesis of cofactors
lww01523
Antifolate resistance
lww04981
Folate transport and metabolism
Module
lww_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
lww00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
102726305 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
102726305 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
102726305 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
102726305 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102726305 (SHMT2)
Enzymes [BR:
lww01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
102726305 (SHMT2)
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Ortholog
Paralog
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Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
102726305
NCBI-ProteinID:
XP_006740127
UniProt:
A0A2U3Y8R8
LinkDB
All DBs
Position
Unknown
AA seq
504 aa
AA seq
DB search
MLPFSLLWATRPLQRCGQLVRRAIRCQHSEVAQTQTGEATSGWTGQESLSDSDPEMWELL
QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
QRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRVSATSIFFESMPYKLNPKTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMREV
CDEVKAHLLADMAHISGLVAAKVIPSPFKHADVVTTTTHKTLRGARSGLIFYRKGTRAVD
PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYALQVLKNARA
MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRRVVNFIDEGVNIGLEVKSKTAKLQDFKSFLLKDPETSH
RLADLRQRVEQFARAFPMPGFDER
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgctgcccttctctttgctctgggcgactcggcctctgcagagatgtggtcagctggtc
aggagggccatccggtgccagcacagtgaggtggcccagacccagactggagaagcaacc
agcggctggacaggccaggagagtctgtcagacagtgaccctgagatgtgggagctgctg
cagagggagaaggacaggcagtgtcgtggcctggagctcattgcctcagagaacttctgc
agccgagcagcgctggaggccctggggtcctgtctcaacaacaagtactcggagggttat
cctggcaagagatattatggaggagcagaggtagtggatgaaattgagctgctgtgtcag
cagcgggccttggaggcctttgacctggatcctgcgcagtggggagtcaatgtccagcca
tactcaggctctccggctaatctggctgcctacacagcccttctgcagcctcatgaccga
attatggggctggacttgcccgatgggggccatcttactcacggctacatgtctgatgtc
aagcgggtctcagccacgtccatcttctttgagtccatgccctataagctaaatcccaaa
accggcctcatcgactacgaccagctggcactgactgcccgacttttccgcccacggctc
attatagctggtaccagtgcctacgcgcgcctcattgactatgcccgcatgagagaggtg
tgtgatgaggtcaaggcgcacctcctggcagacatggcccacatcagtggcctcgtggct
gccaaggtgatcccctcacctttcaagcatgcggatgtcgtcaccaccaccactcacaag
acccttcgaggggccaggtcaggactcatcttctaccggaaggggacgcgggctgtggat
cccaagactggccgggagatcccttacacatttgaggaccgaatcaactttgctgtgttc
ccatccctgcaggggggcccccacaaccatgccattgctgccgtggctgtggccctaaag
caggcctgcacccccatgttccgggagtacgccctgcaggttctgaagaatgctcgggcc
atggctgatgccctgctagagcgaggctactcactcgtgtctggtggcaccgacaaccac
ctagtgctagtggatctgcggcccaagggcctggatggagctcgggctgagcgggtgctg
gaactggtctccatcacagccaacaagaacacctgtcctggagaccgaagtgccatcaca
cccgggggcctgcggctcggggccccagccttgacctctcgacagttccgtgaggatgac
ttccggagagttgtgaactttatagatgaaggtgtcaacattggcttggaggtgaagagc
aagactgccaaactccaggatttcaaatccttcctgctcaaggacccagaaacaagtcat
cggctggccgacctcaggcaacgggtggagcagtttgccagggccttccccatgcctggt
tttgatgagcgctga
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