KEGG   Leptonychotes weddellii (Weddell seal): 102726528
Entry
102726528         CDS       T08708                                 
Symbol
PLD2
Name
(RefSeq) phospholipase D2
  KO
K01115  phospholipase D1/2 [EC:3.1.4.4]
Organism
lww  Leptonychotes weddellii (Weddell seal)
Pathway
lww00564  Glycerophospholipid metabolism
lww00565  Ether lipid metabolism
lww01100  Metabolic pathways
lww04014  Ras signaling pathway
lww04024  cAMP signaling pathway
lww04071  Sphingolipid signaling pathway
lww04072  Phospholipase D signaling pathway
lww04144  Endocytosis
lww04666  Fc gamma R-mediated phagocytosis
lww04724  Glutamatergic synapse
lww04912  GnRH signaling pathway
lww04928  Parathyroid hormone synthesis, secretion and action
lww05200  Pathways in cancer
lww05208  Chemical carcinogenesis - reactive oxygen species
lww05212  Pancreatic cancer
lww05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:lww00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    102726528 (PLD2)
   00565 Ether lipid metabolism
    102726528 (PLD2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    102726528 (PLD2)
   04072 Phospholipase D signaling pathway
    102726528 (PLD2)
   04071 Sphingolipid signaling pathway
    102726528 (PLD2)
   04024 cAMP signaling pathway
    102726528 (PLD2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    102726528 (PLD2)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    102726528 (PLD2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    102726528 (PLD2)
   04928 Parathyroid hormone synthesis, secretion and action
    102726528 (PLD2)
  09156 Nervous system
   04724 Glutamatergic synapse
    102726528 (PLD2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102726528 (PLD2)
   05208 Chemical carcinogenesis - reactive oxygen species
    102726528 (PLD2)
   05231 Choline metabolism in cancer
    102726528 (PLD2)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    102726528 (PLD2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:lww04131]
    102726528 (PLD2)
Enzymes [BR:lww01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.4  phospholipase D
     102726528 (PLD2)
Membrane trafficking [BR:lww04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    102726528 (PLD2)
 Endosome - Golgi transport
  Others
   Others
    102726528 (PLD2)
SSDB
Motif
Pfam: PLDc PX PLDc_2 PH
Other DBs
NCBI-GeneID: 102726528
NCBI-ProteinID: XP_006743191
UniProt: A0A2U3YHK0
LinkDB
Position
Unknown
AA seq 933 aa
MAATPSSLFPSGGDLDSSQLHMEPDELDTLREGEDPADRMHPFLAIYDLQPLKMHPLVFA
PGVPVTAQVVGTERYTSGSKVRTCTLYSVRLTHGAFTWTTKKKFRHFQELHRDLLRHKVL
MSLLPLARFGMAHPPAREATNREIPSLPRVGPEGSARHASSKQKYLENYLNRLLTMSFYR
NYHAMTEFLEVSRMSFIPDLGSKGLEGVVRKRSGGHRVPGLTCCGRDQVCYRWSKRWLVV
KDSFLLYMSLETGTISFVQLFDPGFEVQVGKRSTEARYGVRIDTSHRSLILKCGSYRQAR
WWGQEITELAQGPGRDFIHLHQHDSYAPPRPGTLARWFVNGAGYFAALADAILRAQEEIF
ITDWWLSPEIYLKRPAHSDDWRLDIMLKKKAEEGVRVSILLFKEVELALGINSGYSKRVL
MQLHPNIKVMRHPDQVTLWAHHEKLLVVDQAVAFLGGLDLAYGRWDDLRYRLTDLGDPSG
PVAPQPTPLGSDTPGSPDLSQNQLFWLGKDYSNLITKDWVQLDRPFEDFIDRETTPRMPW
RDVGVAVHGLPARDLARHFIQRWNFTKMTKAKYKIPMYPYLLPKSTSTADQLPFTLPGGQ
CATVQVLRSVDRWSAGTLENSILNAYLHTIRESQHFLYIENQFFISCSDGRTVLNKVGDE
IVDRILKAHKLGQCFRVYVLLPLLPGFEGDITTGGGNSIQAILHFTYRTLCRGEYSILHR
LKAAMGTAWRDYMSICGLRTHGELGGHPVSELIYIHSKMLIADDRTVIIGSANINDRSLL
GKRDSELAVLIEDTEMEPSLMDGRDYQAGRFALSLRKHCFSVILGADARPDLDLRDPVCD
GFFQLWQDTAGNNANIYEQIFRCLPSNATHSLRALREYVAVEPLATVSPPLARSELTQVQ
GHLVHFPLKFLEDESLLPTLGSKEGVMPLEVWT
NT seq 2802 nt   +upstreamnt  +downstreamnt
atggcggcgaccccctcgagcctcttcccctctgggggcgacctggactctagccagttg
catatggagcccgatgagttggacactctgagggagggagaggacccagctgaccggatg
cacccctttctggccatctacgacctgcagcctctgaaaatgcaccccttggtgttcgcc
cctggggtcccggtcacggcccaagtggtgggcactgaaagatacaccagtggatccaag
gtgcggacctgcaccctgtattctgtccgcttgacgcatggcgcctttacctggacgacc
aagaagaagttccgtcatttccaggagctgcatcgggacctcctaagacacaaagtcttg
atgagcctgctccctctggcgcgctttggcatggcccaccctccagcccgcgaggccacc
aaccgagagataccctctctgccccgagtgggtcctgagggctccgccagacatgcgtcc
agcaaacagaagtacctggagaattacctcaaccgcctcctgaccatgtctttctaccgc
aactaccacgccatgacagaattcctggaagtcagtcgaatgtcctttatcccagacctt
ggctccaaaggactggagggagtggtccggaagcgctccgggggccaccgagttcctggc
ctcacgtgctgcggccgagaccaagtctgttaccgctggtccaagaggtggctggtggtg
aaggactccttcctgctgtacatgagcttggagacgggcaccatctcctttgttcagctc
ttcgaccctggcttcgaggtgcaggtggggaaaaggagcacggaggcgcgctacggggtc
aggatcgacacctcccacaggtccctgattctcaagtgcggcagctaccggcaggcacgg
tggtggggccaggagatcactgagctggcccagggccccggcagagacttcatacatctg
caccagcatgacagctacgccccgccccggcctgggaccctggcccggtggtttgtgaat
ggggcaggttactttgctgccctggcagatgccatcctacgagctcaagaggagattttc
atcacagattggtggttgagtcctgaaatttacctgaagcgtccggcccattcagatgac
tggagacttgacattatgctcaagaagaaggcggaggagggtgtccgtgtgtccatccta
ctgtttaaggaagtggagttggccttgggcattaacagtggctatagcaagagagttctg
atgcagctgcaccccaacataaaggtcatgcgccacccagaccaggtgaccctgtgggcc
catcatgagaagctcctggtcgtggaccaagcagtggccttcctgggggggctggacctc
gcctacggccgctgggatgacctgcgctaccgcctgactgacctcggggacccctctgga
ccagtggccccacagcctacccccctgggctccgacactccaggaagcccagacctctcg
caaaaccaactcttctggctgggcaaagactacagcaatcttatcaccaaggactgggtg
cagctggaccggccttttgaggatttcattgacagggagaccacacctcggatgccatgg
cgggacgttggggtggccgtgcacggtctccccgcccgggacctggctcggcatttcatc
cagcgctggaacttcaccaagatgaccaaggccaagtacaagatacccatgtacccctac
ctgctgcccaaatccaccagcactgcagaccagctccccttcacgctcccaggggggcag
tgcgccacggttcaggtcttgcggtctgtggaccgctggtcagcagggactttggagaat
tccatcctcaatgcctacctgcacaccatcagggagagccagcactttctgtatatcgag
aatcagttcttcattagctgctcagatgggcggaccgttctcaacaaggtgggcgatgag
attgtggatagaatcctgaaggcccacaaacttgggcagtgcttccgagtctacgtgctt
ttgcccctgctgcccggttttgagggtgacatcactacaggtggtgggaactccatccag
gccattctgcacttcacctacaggaccctgtgccgtggggagtattcgatcctacatcgc
ctcaaagcagccatggggacagcgtggcgggactatatgtccatctgtgggcttcgcacc
catggcgagctgggcgggcacccggtctcagagctgatctatatccacagcaagatgctc
atcgcggatgaccggacagtcatcattggctccgccaacatcaatgaccgcagcttgctg
gggaagcgggacagtgagctggccgtgctgatcgaggacaccgagatggagccgtccctc
atggacggcagggactatcaggcgggcaggttcgccttgagtttgcggaagcattgcttc
agtgtgattcttggggcagatgcccggccagacctggatctccgagaccctgtgtgtgat
ggcttcttccagctgtggcaagacacagctgggaacaacgccaacatctatgagcagatc
ttccgctgcctgccatccaatgccacgcactccctgcgggcactccgcgagtacgtggcc
gtggagcccctggccacagtcagcccacctctggccaggtctgagctcacccaggtccag
ggccacctggtccactttcccctcaagttcctggaggatgagtctttgctgcccaccctg
gggagcaaggaaggcgtgatgcccctcgaagtgtggacatag

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