Leptonychotes weddellii (Weddell seal): 102729021
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Entry
102729021 CDS
T08708
Symbol
RPS6KB2
Name
(RefSeq) ribosomal protein S6 kinase beta-2 isoform X1
KO
K04688
ribosomal protein S6 kinase beta [EC:
2.7.11.1
]
Organism
lww
Leptonychotes weddellii (Weddell seal)
Pathway
lww01521
EGFR tyrosine kinase inhibitor resistance
lww01522
Endocrine resistance
lww04012
ErbB signaling pathway
lww04066
HIF-1 signaling pathway
lww04140
Autophagy - animal
lww04150
mTOR signaling pathway
lww04151
PI3K-Akt signaling pathway
lww04152
AMPK signaling pathway
lww04211
Longevity regulating pathway
lww04213
Longevity regulating pathway - multiple species
lww04350
TGF-beta signaling pathway
lww04371
Apelin signaling pathway
lww04666
Fc gamma R-mediated phagocytosis
lww04714
Thermogenesis
lww04910
Insulin signaling pathway
lww04931
Insulin resistance
lww05163
Human cytomegalovirus infection
lww05165
Human papillomavirus infection
lww05170
Human immunodeficiency virus 1 infection
lww05200
Pathways in cancer
lww05205
Proteoglycans in cancer
lww05207
Chemical carcinogenesis - receptor activation
lww05210
Colorectal cancer
lww05212
Pancreatic cancer
lww05221
Acute myeloid leukemia
lww05224
Breast cancer
lww05225
Hepatocellular carcinoma
lww05226
Gastric cancer
lww05231
Choline metabolism in cancer
lww05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
lww00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
102729021 (RPS6KB2)
04350 TGF-beta signaling pathway
102729021 (RPS6KB2)
04371 Apelin signaling pathway
102729021 (RPS6KB2)
04066 HIF-1 signaling pathway
102729021 (RPS6KB2)
04151 PI3K-Akt signaling pathway
102729021 (RPS6KB2)
04152 AMPK signaling pathway
102729021 (RPS6KB2)
04150 mTOR signaling pathway
102729021 (RPS6KB2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
102729021 (RPS6KB2)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
102729021 (RPS6KB2)
09152 Endocrine system
04910 Insulin signaling pathway
102729021 (RPS6KB2)
09149 Aging
04211 Longevity regulating pathway
102729021 (RPS6KB2)
04213 Longevity regulating pathway - multiple species
102729021 (RPS6KB2)
09159 Environmental adaptation
04714 Thermogenesis
102729021 (RPS6KB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102729021 (RPS6KB2)
05205 Proteoglycans in cancer
102729021 (RPS6KB2)
05207 Chemical carcinogenesis - receptor activation
102729021 (RPS6KB2)
05231 Choline metabolism in cancer
102729021 (RPS6KB2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102729021 (RPS6KB2)
09162 Cancer: specific types
05210 Colorectal cancer
102729021 (RPS6KB2)
05212 Pancreatic cancer
102729021 (RPS6KB2)
05225 Hepatocellular carcinoma
102729021 (RPS6KB2)
05226 Gastric cancer
102729021 (RPS6KB2)
05221 Acute myeloid leukemia
102729021 (RPS6KB2)
05224 Breast cancer
102729021 (RPS6KB2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
102729021 (RPS6KB2)
05163 Human cytomegalovirus infection
102729021 (RPS6KB2)
05165 Human papillomavirus infection
102729021 (RPS6KB2)
09167 Endocrine and metabolic disease
04931 Insulin resistance
102729021 (RPS6KB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102729021 (RPS6KB2)
01522 Endocrine resistance
102729021 (RPS6KB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lww01001
]
102729021 (RPS6KB2)
Enzymes [BR:
lww01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
102729021 (RPS6KB2)
Protein kinases [BR:
lww01001
]
Serine/threonine kinases: AGC group
RSK family [OT]
102729021 (RPS6KB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_C
Kinase-like
Pkinase_fungal
ABC1
Seadorna_VP7
Motif
Other DBs
NCBI-GeneID:
102729021
NCBI-ProteinID:
XP_006751449
UniProt:
A0A2U3Z632
LinkDB
All DBs
Position
Unknown
AA seq
482 aa
AA seq
DB search
MAAVFDLDLETEEGSEGEPELSPSDVCPLAESRAAGLEPVGHCEEVELTETSVNLGPERI
GPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHMRAERNI
LESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLAL
GHLHSQGIIYRDLKPENIMLNSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILV
RSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLTLPPYLTPDARDLVKK
FLKRNPGQRIGGGPGDAADVQRHPFFRHINWDDLLARRIDPPFRPSLQSEEDVSQFDSHF
TRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLHSSPRTPV
SPLKFSPFEGFRPGSGPPEPSEPPLPPLLPPPPPPPSSTAPLPIRPPSGTKKSKRGRGRP
GR
NT seq
1449 nt
NT seq
+upstream
nt +downstream
nt
atggcggccgtgtttgacctggacctggagacggaggaaggcagcgagggcgagccagag
ttgagcccctcggacgtgtgtccccttgccgagtcgagggcggctggcctggagcctgtg
ggacactgtgaggaggtggagctgactgagaccagtgtgaacctaggccctgagcgcatc
gggccccactgctttgagctgctgcgtgtgctgggcaaggggggctatggcaaggtgttc
caagtgcgaaaggtgcagggcaccaacttgggcaaaatatatgccatgaaagtcctgagg
aaggccaaaattgtgcgcaacgccaaggacacagcacacatgcgggctgaacggaacatt
ctagagtcagtgaagcaccccttcattgtggaactggcctatgccttccagactggtggc
aaactctacctcatcctcgagtgtctcagtggcggtgagctcttcacgcatctggagcga
gagggcatcttcctggaagacacggcctgtttctacctggcagagatcacactggccctg
ggccatctccactcccaaggcatcatctaccgggacctcaaacctgagaacatcatgctc
aacagccagggccacatcaaactgacagactttggactctgcaaggagtcgatccatgag
ggcgccgtcacccatactttctgtggcaccattgagtacatggcccctgagattctggta
cgcagtggccacaaccgggcggtggactggtggagcctgggggccctgatgtatgacatg
ctcactggatcgccacccttcactgcagagaaccggaagaaaaccatggacaagatcatc
aaagggaagctgacgctgcccccctacctcaccccggatgcccgggaccttgtcaaaaag
tttctgaagcggaatcctggccaacggatcgggggtggccctggggatgctgctgatgtg
cagaggcaccccttcttccggcacattaattgggacgacctcctggctcgccgcatcgac
ccccctttcaggccttctctgcagtcagaggaggacgtgagccagtttgactcccacttc
acgcggcagacgccagtggacagtcccgatgatacggccctcagcgagagcgccaaccag
gccttcctgggcttcacatatgtggcaccctccgtcctggacagcatcaaggagggcttc
tccttccagcccaagctgcgctcccccaggcgcctccacagcagcccccggaccccggtc
agccccctgaagttctcgccctttgagggattccggcccggctctggcccaccggagccc
tcggagccccctctacctcctctcctgccgccgccgccaccaccaccctcgagcaccgcc
cccctccccatccgacccccctcagggaccaagaagtctaagaggggccgtgggcgccca
gggcgctag
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