Leptonychotes weddellii (Weddell seal): 102734862
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Entry
102734862 CDS
T08708
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1 isoform X3
KO
K04514
Rho-associated protein kinase 1 [EC:
2.7.11.39
]
Organism
lww
Leptonychotes weddellii (Weddell seal)
Pathway
lww04022
cGMP-PKG signaling pathway
lww04024
cAMP signaling pathway
lww04062
Chemokine signaling pathway
lww04071
Sphingolipid signaling pathway
lww04270
Vascular smooth muscle contraction
lww04350
TGF-beta signaling pathway
lww04360
Axon guidance
lww04510
Focal adhesion
lww04519
Cadherin signaling
lww04520
Adherens junction
lww04530
Tight junction
lww04611
Platelet activation
lww04670
Leukocyte transendothelial migration
lww04810
Regulation of actin cytoskeleton
lww04921
Oxytocin signaling pathway
lww05135
Yersinia infection
lww05163
Human cytomegalovirus infection
lww05200
Pathways in cancer
lww05205
Proteoglycans in cancer
lww05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
lww00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
102734862 (ROCK1)
04071 Sphingolipid signaling pathway
102734862 (ROCK1)
04024 cAMP signaling pathway
102734862 (ROCK1)
04022 cGMP-PKG signaling pathway
102734862 (ROCK1)
09133 Signaling molecules and interaction
04519 Cadherin signaling
102734862 (ROCK1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
102734862 (ROCK1)
04520 Adherens junction
102734862 (ROCK1)
04530 Tight junction
102734862 (ROCK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
102734862 (ROCK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
102734862 (ROCK1)
04670 Leukocyte transendothelial migration
102734862 (ROCK1)
04062 Chemokine signaling pathway
102734862 (ROCK1)
09152 Endocrine system
04921 Oxytocin signaling pathway
102734862 (ROCK1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
102734862 (ROCK1)
09158 Development and regeneration
04360 Axon guidance
102734862 (ROCK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102734862 (ROCK1)
05206 MicroRNAs in cancer
102734862 (ROCK1)
05205 Proteoglycans in cancer
102734862 (ROCK1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
102734862 (ROCK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
102734862 (ROCK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lww01001
]
102734862 (ROCK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
lww03036
]
102734862 (ROCK1)
Enzymes [BR:
lww01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
102734862 (ROCK1)
Protein kinases [BR:
lww01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
102734862 (ROCK1)
Chromosome and associated proteins [BR:
lww03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
102734862 (ROCK1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH_MRCK
PH
C1_1
Cortex-I_coil
Pkinase_C
Par-4_C
CC_Bre1
APH
Motif
Other DBs
NCBI-GeneID:
102734862
NCBI-ProteinID:
XP_006733103
UniProt:
A0A2U3XNQ7
LinkDB
All DBs
Position
Unknown
AA seq
1354 aa
AA seq
DB search
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNDNRSSPNV
DKSLQENLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLEST
VSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKL
AQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSVSQLESLNRELQERNRILENSKTQTD
KDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDLLN
HSEKEKNNLEIDLNYKLKSLQQHLEQEVNEHKVTKACLTDKHQSIEEAKSVAMCEMEKKL
KEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTENKERMEDEVKNLSLQLEQES
NKRLLLQNELKTQAFEADNLKGLEKHMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNREYLKKIQELQSEKETLATQLDLAETKAE
SEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEETNSMLTKDIELLRKENE
ELTDKMRRAEEEYKLKKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQTVVKHQKELNDMQAQLVEECTHRNELQMQL
ASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSIPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALE
CRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTS
NT seq
4065 nt
NT seq
+upstream
nt +downstream
nt
atgtcgactggggacagttttgagactcggtttgaaaaaatcgacaacctgctgcgggat
cccaaatcggaagtgaattcagattgtttgctggatggattggatgctttggtatatgat
ttggattttcctgccttaagaaaaaacaaaaatattgacaactttttaagcagatataaa
gacacaataaataaaattagagatttacgaatgaaagctgaagattatgaagtagtgaag
gtgattggtagaggtgcatttggagaagttcaattggtaaggcataaatccactaggaag
gtatatgctatgaagcttctcagtaaatttgaaatgattaagagatccgattctgccttt
ttctgggaagaaagggacatcatggcttttgctaacagcccttgggtcgtccagcttttt
tatgcattccaagatgatcgttatctctacatggtgatggagtacatgcctggtggagat
cttgtaaacttaatgagcaactatgatgtgcctgaaaaatgggcacgattctataccgca
gaagtagttcttgcattggatgcaatccattccatgggtttcattcacagagatgtgaaa
cctgataacatgctgctggataaatctggacatttgaagttagcagattttggtacttgt
atgaagatgaataaggaaggtatggtacgatgtgatacagcagttggaacacctgattac
atttcccctgaagtattaaaatctcaaggtggtgatggctattatggacgtgaatgtgac
tggtggtcagttggggtctttttatatgaaatgcttgtaggtgatacacccttttatgca
gattctctggttggaacttacagtaagattatgaaccataaaaattcacttactttccct
gatgataatgatatatcaaaagaagcaaaaaatcttatttgtgccttccttactgacaga
gaggtgagattagggcgaaatggtgtagaagaaatcaaacgacatctcttcttcaaaaat
gatcaatgggcttgggaaacactcagagacactgtagcaccagttgtaccggatttaagt
agtgacatcgatacaagtaattttgatgacttggaagaagataaaggagatgaagaaaca
ttccccatacctaaagcttttgttggcaatcagttaccttttgtaggatttacgtattat
agcaatcgtagatacttatcttcagcaaatcctaatgataaccgaagtagccccaatgtg
gataagagcttgcaggaaaatttgcaaaaaacaatttataagctggaagaacagctgcat
aatgaaatgcaattaaaagatgaaatggagcagaagtgcagaacttcaaacataaaacta
gacaagataatgaaagaattggatgaagaggggaatcaaagaagaaacctagaatctaca
gtgtctcagattgagaaggagaaaatgttgctacagcatagaattaatgagtaccagaga
aaagcagaacaggaaaatgagaagaggaggaatgtagaaaatgaagtttctacattaaag
gatcagttggaagacttaaagaaagtaagtcaaaattcacagcttgctaatgagaagctg
gcacaattacaaaagcagctagaagaagccaatgacttacttagaacagaatcagacaca
gccgtaagattaaggaagagtcacacagagatgagtaagtcagttagtcagctagagtcc
ctaaacagagaattgcaggagagaaatagaattttagagaattccaagacacagacggac
aaggactattaccagctgcaagctgtattagaagctgaacgaagagacagaggtcatgat
tctgagatgattggagaccttcaagctcgaattacatctttacaagaggaggtgaagcat
ctcaaacataatcttgaaagagtggaaggagaaagaaaagaagctcaagacctgcttaat
cactcagaaaaggaaaaaaataatttagagatagatttaaactataagcttaaatcatta
caacaacatttagaacaagaggtaaatgaacataaagtaaccaaagcttgtttaactgac
aaacatcaatctattgaagaggcaaagtctgttgcaatgtgtgaaatggaaaaaaagctg
aaggaagagagagaagctcgagagaaggctgaaaatagagttgttcagattgagaaacag
tgttcaatgctagatgttgatctgaaacaatctcagcagaagctcgagcatttgactgaa
aataaagaaaggatggaggatgaagttaagaatctatcccttcaactggagcaggaatca
aacaagcgactgttgttacagaatgaattgaagactcaagcatttgaagcagacaattta
aaaggtttagaaaagcacatgaaacaggaaataaatactttattggaagcaaagagatta
ttagaatttgaattagctcagcttacaaaacagtatagaggaaatgaaggacagatgcgg
gagctccaagatcagcttgaagctgagcagtatttctcgacactttataaaacccaggta
aaggaacttaaggaagaaattgaagaaaaaaacagagaatatttaaagaaaatacaagag
ctacaaagtgagaaggaaactcttgctactcagttggatctagcagaaacaaaagctgag
tctgagcagttggctcgagggctgctggaagaacagtattttgaattaacccaagaaagc
aagaaagctgcttccagaaatagacaagagattacagataaagatcatactgttagtcgg
cttgaagaaacaaacagcatgttaaccaaagatattgaattattaagaaaagaaaatgaa
gagctaactgataaaatgaggagggcagaggaagaatataaattgaagaaggaggaggag
atcagtaatcttaaggctgcctttgaaaagaatatcaatacagaaagaacccttaaaacg
caggctgttaacaagttggcagaaataatgaatcggaaagattttaaaattgatagaaag
aaagctaatacacaggatttgagaaagaaggaaaaggaaaatcgaaagctgcaactggaa
ctcaaccaagaaagagagaaattcaaccagacggtagtgaaacatcagaaggaactgaat
gacatgcaagcgcaattggtagaagaatgtacacataggaatgaacttcagatgcaattg
gctagcaaagagagtgatattgagcaattgcgtgctaaacttttggacctttcggattct
acaagtgttgctagttttcctagtgctgatgaaactgatggtaaccttccagagtcaaga
attgaaggttggctttcaataccaaatagaggaaatatcaaacgatatggctggaagaaa
cagtatgttgtggtaagcagcaaaaaaattttgttctataatgatgaacaagataaggaa
caatccaatccatccatggtattggacatagataaattgtttcacgttcgacctgtaacc
caaggagatgtttacagagctgaaactgaagaaattcctaaaatattccagatactatat
gcaaatgaaggtgaatgtagaaaagatgtagagatggaaccagtacaacaagcggagaag
actaattttcaaaaccacaaaggccatgagttcattcctacactctaccactttcctgcc
aactgtgaggcatgtgccaaacctctctggcatgtttttaagccacctcctgccctggaa
tgtcgaagatgccacgtgaagtgccacagagatcacttggataagaaagaggacttaatt
tctccatgtaaagtaagttatgatgtaacatcagcaagagatatgctgctgttagcatgt
tctcaggatgaacaaaaaaaatgggtaacacatttggtaaagaagatccctaagaatcca
ccatctggttttgttcgtgcatcccctcgaacgctttctacaagatctactgcaaatcag
tctttccgaaaagtggtcaaaaatacatctggaaaaactagttaa
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integrated database retrieval system
