Leptonychotes weddellii (Weddell seal): 102735903 Help Entry 102735903         CDS       T08708                                  Symbol TOP2A Name (RefSeq) DNA topoisomerase 2-alpha   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism lww  Leptonychotes weddellii (Weddell seal) Pathway lww01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:lww00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     102735903 (TOP2A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:lww03032]     102735903 (TOP2A)    03036 Chromosome and associated proteins [BR:lww03036]     102735903 (TOP2A) Enzymes [BR:lww01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      102735903 (TOP2A) DNA replication proteins [BR:lww03032]  Eukaryotic type   DNA Topoisomerases    102735903 (TOP2A) Chromosome and associated proteins [BR:lww03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     102735903 (TOP2A)   Centrosome formation proteins    Centriole proteins     102735903 (TOP2A) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT Toprim HATPase_c Microp_apicomplexa_20 Motif Other DBs NCBI-GeneID:  102735903 NCBI-ProteinID:  XP_006746252 UniProt:  A0A2U3YR93 LinkDB All DBs Position Unknown AA seq 1514 aa AA seqDB search MEVSPLQPVNENMQISKTKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ MWVYDEDIGINYREVTFVPGLYKIFDEILGVENNLISIWNNGKGIPVVEHKVEKMYVPAL IFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQTWMDNMGR AGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGN KLPVKGFRSYVDMYLKDKVDETGNPLKIIHEQVNPRWEVCLTMSEKGFQQISFVNSIATS KGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHMWIFVNALIENPTFDSQTKEN MTLQVKSFGSTCQLSEKFIKAATGCGIVESILNWVKFKAQVQLNKKCSAVKHNRIKGIPK LDDANDAGGRNSNECTLILTEGDSAKTLAVSGLGVVGRDKYGVFPLRGKILNVREASHKQ IMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHN WPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKSSTPNHKKWKVKYYKGLGTST SKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDDRKEWLTHFMEDRRQRKLLGL PEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVDGLKPGQRKVLFTCFKRNDKR EVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNLNLLQPIGQFGTRLHGGKDS ASPRYIFTMLSPLTRLLFPPKDDHTLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGW SCKIPNFDIREVVNNIRRLMDGEEPLPMLPSYKNFRGTIEELAPNQYVISGEVAILNSTT IEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYHTDTTVKFVVKMTEEKLAEA ERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGM LGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQRGYDSDPVKAWKEAQLKVPDE EENEESDNENEAEKSDSVRDSGPTFNYLLDMPLWYLTKEKKDELCKLRNEKEQELETLKR KSPSDLWKEDLAAFIEELEAVETKEKQEEQIGLPGKGGKAKGKKTQMAEVLPSPSGKRVI PRVTVEMKAEAEKKIKKKIKNENTEGSPPEDSIELEGLKQRLEKKQKREPGTKTKKQTTL PFKPIKKGKKRNPWSDSESDMSSDESNFDVPPREIEPRRAATKTKFTVDLDSDDDFSDFD EKTQDEDFVPSSDVSPLKTKASPKHTTKELKPQKSATSVMDLDADDAKDGVPFPAGSPAA DFSADTEILNPVSKKKVAVKKTAAKSQSSTSSTGAKKRAAPKGPKTDPGWNSDVPQKPDP PKTKIRRKRKPSTSDDSDSNFEKMISKAVTNKKSKGESEDFHLDLDSAVAPRAKSGRAKK PIKYLEESDEDDLF NT seq 4545 nt NT seq  +upstreamnt  +downstreamnt atggaggtgtcaccattgcagcctgtaaatgaaaatatgcaaatcagcaaaacaaagaaa aatgaagatgctaagaaaagactgtctattgaaagaatctatcaaaagaaaacccaactg gaacatattttgctccgcccagacacctacattggctctgtggaattagtgacccagcaa atgtgggtttacgatgaagatattggcattaactatagggaagtcacctttgtccctggg ttgtacaaaatctttgatgagatcctaggagtggaaaacaatttaattagtatatggaat aatgggaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagctctc atctttggacagctcctaacttctagtaactatgatgatgatgaaaagaaagtaacaggt ggtcgaaatggctatggggccaaattgtgtaacatattcagtaccaaatttactgtggaa acagccagtagagaatacaagaaaatgttcaaacagacatggatggataacatggggaga gctggtgagatggaactcaaaccctttaatggggaagattatacatgtattaccttccag cctgacttgtccaagtttaaaatgcaaagcctagataaagatattgttgcactaatggtt agaagagcatatgatattgctggatccacgaaagatgtcaaagtctttctcaatggaaat aagctgccagtaaaaggattccgtagctatgtagatatgtatttgaaggataaggtagat gaaactggcaatccactgaaaattatccacgaacaagtaaaccccaggtgggaagtatgc ttaacaatgagtgaaaaaggctttcagcaaattagctttgtcaacagcattgctacttcc aagggtggcagacatgttgattatgtagctgatcagattgtgactaaacttgttgatgtt gtgaagaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatg tggatttttgtgaatgccttaattgaaaacccaacctttgactctcagacaaaagaaaac atgactttacaagtcaagagctttggatcaacatgccaattaagtgaaaaattcatcaaa gctgcaactggctgtggtattgtggaaagcatactaaactgggtgaagtttaaggcccaa gtccaattaaacaagaagtgttcagctgtaaaacataatagaatcaagggaattcccaaa ctcgatgatgccaatgatgcagggggtcgaaactccaatgagtgtacacttatcctgact gagggagactcagctaaaactttggctgtttcaggccttggtgtagttgggagagacaaa tatggggttttcccacttagaggaaaaatactcaatgttcgagaagcttctcataaacag atcatggaaaatgccgaaattaacaatatcatcaagattgtgggtcttcagtacaagaaa aactatgaagatgaagattcattgaagactcttcgttatggaaagataatgattatgaca gatcaggaccaagatggttcccatatcaaaggcctgctgattaattttatccatcacaac tggccctctcttctacggcatcgttttctggaagaatttatcactcccattgtaaaggtg tctaaaaacaaacaagaaatggcattctatagccttcctgaatttgaagaatggaagagt tctactccaaatcataaaaaatggaaagtcaagtactacaaaggtttgggcaccagcaca tcaaaagaagctaaagaatactttgcagatatgaaaagacatcgtattcaattcaaatat tctggtcctgaagatgatgctgccatcagcctggcctttagcaagaaacagatcgatgat cgaaaggaatggttaactcatttcatggaggatagaaggcaacggaagttacttggcctt cctgaggattacttgtatggacaaactaccacatatctgacatacaatgacttcataaat aaggaacttatcctgttctcaaattctgataacgagagatctatcccatctatggtggat ggcttgaaaccaggtcaaagaaaagttttgtttacctgtttcaaacggaatgacaagcga gaggtgaaagttgcccagttagctgggtcagtggctgagatgtcctcttatcatcatggt gagatgtcactaatgatgaccattatcaatttggctcagaattttgtgggtagcaataat ctgaacctcttgcagcccattggtcagtttggtactaggctgcatggtggcaaggattct gctagtcctcgatacatcttcacaatgctcagccctttgactcggttgttatttccacca aaagatgatcatacattgaagtttttatatgatgacaatcaacgtgttgaacctgaatgg tacattcctattatacccatggtgctgataaatggtgctgaaggaatcggtactgggtgg tcctgcaaaatccccaactttgatattcgtgaagttgtaaataatatcaggcgtttgatg gatggagaagaacctttgccaatgcttccaagttacaagaacttcaggggtactattgaa gagctggctccaaatcaatatgtgattagtggtgaagtggctattcttaattccacaacc attgaaatctcagagcttcctatcagaacatggacccagacatataaagaacaggttcta gaacctatgttgaatggaactgagaagacaccacctctcataacagattatagggaatac catacagacactactgtgaagtttgttgtgaaaatgactgaagagaaactggcagaggca gagagagtgggactacacaaagtattcaaactccaaactagtctcacatgcaactctatg gtgctttttgaccatgtaggatgtttaaagaaatacgacacagtgttggatattctaaga gacttctttgaactcaggcttaaatattatggattaagaaaagaatggcttctaggaatg cttggtgctgaatctgctaaactgaacaatcaggctcgctttatcttagagaaaatagat ggcaaaataatcattgaaaataagcctaagaaagaattaattaaagttctgattcagagg ggatatgattcagatcccgtgaaggcttggaaagaagcccagctaaaggtaccagatgaa gaagagaatgaagagagtgacaatgaaaatgaagctgaaaagagtgactctgtaagagac tctggaccaaccttcaactaccttcttgatatgcctctttggtatctcaccaaggagaag aaggatgaactgtgcaagctgagaaatgaaaaagagcaagagctagaaacattaaagaga aagagtccatcagatttgtggaaagaagacttggctgcttttattgaagagctggaggct gttgaaacaaaggaaaaacaagaagaacaaataggacttcctgggaaaggggggaaagca aaggggaaaaaaacacaaatggctgaagttttgccttctccatccggtaaaagagtcatc ccccgagtgaccgtggagatgaaagcagaggcagaaaagaaaattaaaaagaaaattaag aatgaaaacactgaagggagccctccagaagacagtatcgaactagaaggtctgaaacaa aggttggagaaaaaacagaaaagagaaccaggtaccaagacaaagaagcaaactacattg ccatttaaaccaatcaaaaaaggaaagaagagaaacccctggtctgattcagaatcagat atgagcagtgacgaaagtaactttgatgtccctccacgagagatagagccacggagagca gcaacaaaaaccaaattcacagtggatttggattcagatgacgatttctcagattttgat gaaaaaactcaagatgaggattttgtcccatcatcagatgttagtccacttaagaccaaa gcttccccaaaacatactaccaaagaactgaagccgcagaaaagtgccacgtcagtaatg gaccttgatgctgatgatgccaaggacggtgtaccatttcctgcaggttctcctgctgct gatttctcagctgacactgaaatcctaaaccctgtttctaaaaagaaggtggcagtgaag aagacggcagcaaaaagtcagtcttccacctccagtacaggtgccaaaaaaagggctgca ccaaaaggacccaaaacggatccaggctggaattctgatgtaccccagaagcctgatccc cccaaaaccaaaattcgccgcaaaaggaagccatccacatctgatgattccgactctaat tttgagaaaatgatttctaaagccgtcacaaacaagaaatccaagggggagagtgaagac ttccatctggacttagactcagctgtggctcctcgggccaaatctggacgggcaaagaaa cctataaagtacctcgaagaatcggacgaagatgatctgttctaa

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