Leptonychotes weddellii (Weddell seal): 102737208
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Entry
102737208 CDS
T08708
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
lww
Leptonychotes weddellii (Weddell seal)
Pathway
lww00230
Purine metabolism
lww01100
Metabolic pathways
lww04927
Cortisol synthesis and secretion
lww04934
Cushing syndrome
lww05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
lww00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
102737208
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
102737208
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
102737208
09167 Endocrine and metabolic disease
04934 Cushing syndrome
102737208
Enzymes [BR:
lww01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
102737208
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8_3rd
SPO22
Motif
Other DBs
NCBI-GeneID:
102737208
NCBI-ProteinID:
XP_030892489
UniProt:
A0A7F8RHA5
LinkDB
All DBs
Position
Unknown
AA seq
583 aa
AA seq
DB search
MVEPVSGTEGGVSPRTGRAFLEGRAARTKPSRQARLSQASLDFIPAPVAVGMEATAVRMN
ACHPHCCSPVPWIYCSSGGWCGRITFDATGNREQRAEVTDHQSGKHKDRRKSSLDVRTLA
SRTSEVGSQRRHSSMARIHSMTIEAPITKVINIINAAQESSPMAVTEALDRVLEILRTTE
LYSPQFGAKDDDPHANDLVGGLMSDGLRRLSGNEYVLSTKNLQQMPSSINAPISLHDVPP
RIARAMENEEYWDFNIFELEAATHKRPLIYLGLKMFARFGICEFLNCSEPTLRSWLQIIE
ASYHSSNPYHNSTHSADVLHATAYFLCKERIKQTLDPVDEVAALIAATVHDVDHPGRTNS
FLCNAGSELAILYNDTAVLESHHAALAFQLTTRDDKCNIFKNMERNDYRTLRQAIIDMVL
ATEMTKHFEHVNKFVNSINKPLAALEVNGEVNRDEEAINTMLRTPENRTLIKRMLIKCAD
VSNPCRPLEQCIEWAGRISEEYFSQTDEEKRQDLPVVMPVFDRNTCSIPKSQISFIDYFI
TDMFDAWDAFVDLPELMQHLDNNFKYWKGLDEMKLRSLRPPPE
NT seq
1752 nt
NT seq
+upstream
nt +downstream
nt
atggttgagcccgtgtctgggacagagggaggggtcagcccaaggacaggaagagcattc
ctggagggacgagctgcacgcacaaagccatcgagacaggcgaggctgagtcaggccagc
ttggatttcatcccagcacccgttgctgtaggaatggaggcaactgctgttcgcatgaat
gcctgccaccctcactgctgctccccagttccctggatttactgctcaagcggtgggtgg
tgtggaaggatcacgtttgatgcaacaggaaatcgagagcagagagctgaagtcacagat
catcagtcaggcaaacataaagacagaaggaaaagctcactagatgtcagaacccttgct
tctcgaacaagcgaagttggcagccagaggcgacactcctccatggcccggatacattcc
atgacgatcgaggcgcccatcaccaaggtaatcaacattatcaatgctgcccaggaaagc
agccccatggctgtgacagaagccttagaccgtgtcctggaaattctaagaaccactgaa
ttatattcaccacagtttggtgctaaggatgatgatcctcatgccaatgaccttgttggg
ggcttaatgtctgatggtttgcgaagactatccgggaatgagtatgttctttcaacaaaa
aatcttcagcagatgcccagcagtataaacgcccccatctcccttcacgacgtcccccca
cggatagctcgggccatggaaaacgaggagtactgggactttaatatatttgaactggag
gctgccacacataaaaggcctttgatttatcttggtctcaaaatgtttgctcgcttcgga
atctgtgaattcttgaactgctccgagccgacgctgagatcgtggttacagatcattgaa
gccagttaccactcttctaacccctaccacaactcgacacactctgccgacgtgcttcac
gccactgcctactttctctgcaaagagaggataaagcaaactttagatccggtcgatgag
gtcgccgcgcttattgcagccaccgtccacgacgtggaccaccctgggcgaaccaactcg
ttcctgtgcaatgctggaagtgagctggccatcttgtataatgacactgctgtgctggag
agccatcatgcggccctggctttccagctgaccacccgagatgacaaatgcaatatcttc
aagaacatggagaggaatgactatcggacgctgcgccaggctattatcgacatggtctta
gccacagaaatgacaaagcacttcgagcacgtcaacaaatttgtcaacagcatcaacaag
cccctggcagcactcgaagtaaatggggaagtgaatagagatgaagaagccataaacact
atgctcaggactccagagaaccggactctgattaaacgaatgctgattaaatgcgcagat
gtgtccaatccctgccgacccctggagcagtgcattgagtgggccggacgcatctcagaa
gaatatttttctcagactgatgaggagaagcggcaggacttacctgtggtgatgccagtt
tttgacagaaacacctgcagcatccccaaatcccagatctccttcattgactacttcatc
acagacatgttcgatgcctgggatgcctttgtagacctgcctgagttaatgcagcatctt
gacaacaactttaaatactggaaaggactggatgaaatgaagctgcggagcctccgaccg
cccccggaatag
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