Leptonychotes weddellii (Weddell seal): 102738300 Help Entry 102738300         CDS       T08708                                  Symbol HIF1A Name (RefSeq) hypoxia-inducible factor 1-alpha   KO K08268   hypoxia-inducible factor 1 alpha Organism lww  Leptonychotes weddellii (Weddell seal) Pathway lww04066   HIF-1 signaling pathway lww04137   Mitophagy - animal lww04140   Autophagy - animal lww04148   Efferocytosis lww04659   Th17 cell differentiation lww04919   Thyroid hormone signaling pathway lww05167   Kaposi sarcoma-associated herpesvirus infection lww05200   Pathways in cancer lww05205   Proteoglycans in cancer lww05208   Chemical carcinogenesis - reactive oxygen species lww05211   Renal cell carcinoma lww05230   Central carbon metabolism in cancer lww05231   Choline metabolism in cancer lww05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:lww00001]  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     102738300 (HIF1A)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     102738300 (HIF1A)    04137 Mitophagy - animal     102738300 (HIF1A)    04148 Efferocytosis     102738300 (HIF1A)  09150 Organismal Systems   09151 Immune system    04659 Th17 cell differentiation     102738300 (HIF1A)   09152 Endocrine system    04919 Thyroid hormone signaling pathway     102738300 (HIF1A)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102738300 (HIF1A)    05205 Proteoglycans in cancer     102738300 (HIF1A)    05208 Chemical carcinogenesis - reactive oxygen species     102738300 (HIF1A)    05230 Central carbon metabolism in cancer     102738300 (HIF1A)    05231 Choline metabolism in cancer     102738300 (HIF1A)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     102738300 (HIF1A)   09162 Cancer: specific types    05211 Renal cell carcinoma     102738300 (HIF1A)   09172 Infectious disease: viral    05167 Kaposi sarcoma-associated herpesvirus infection     102738300 (HIF1A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03000 Transcription factors [BR:lww03000]     102738300 (HIF1A) Transcription factors [BR:lww03000]  Eukaryotic type   Basic helix-loop-helix (bHLH)    Factors with PAS domain     102738300 (HIF1A) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  bHLH_HIF1A PAS_3 PAS_11 HIF-1a_CTAD PAS HIF-1 PAS_9 PAS_4 HLH DDRGK Motif Other DBs NCBI-GeneID:  102738300 NCBI-ProteinID:  XP_006738606 UniProt:  A0A2U3Y4G5 LinkDB All DBs Position Unknown AA seq 823 aa AA seqDB search MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM RLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM GLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGR TMNIKSATWKVLHCTGHIHVYDTNSNQSQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSK TFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQV TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECV LKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTET DDQQLEEVPLYNDVMLPSSNDKLQNINLAMSPLPASETPKPLRSSADPALNQEVALKLEP NPESLELSFTMPQIQDQPASPSDGSTRQSSPEPNSPSEYCFDVDSDMVNEFKLELVEKLF AEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSTSPQSASTVTVFQ PTQIQEPPVTTTSTTAATDELKTVTKDGTEDIKILIASPSPTHVPKVTTSATASPYSDTG SRTASPNRAGKGVIEQTEKSHPRSPNVLSVTLSQRTTIPEEELNPKILALQNAQRKRKIE QDGSLFQAVGIGTLLQQPDDRATTTSLSWKRVKGCKSSEHNGMEQKTIILIPSDLACRLL GQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN NT seq 2472 nt NT seq  +upstreamnt  +downstreamnt atggagggcgccggcggcgcgaacgacaagaaaaagataagttctgaacgtagaaaagaa aagtctagagatgcagctagatctcggagaagtaaagagtccgaagttttttatgagctt gctcatcagttgccacttccccataatgtgagctcgcatcttgataaggcttctgttatg aggcttaccatcagctatttgcgtgtaaggaaacttctggatgctggtgatttggatatt gaagatgaaatgaaggcacagatgaattgcttttatttgaaagccctagatggttttgtt atggttctcacagatgatggtgacatgatttacatttctgataatgtgaataaatacatg ggattgactcagtttgaactaactggacacagtgtgtttgattttactcatccatgtgac catgaggaaatgagagaaatgcttacacacagaaatggtcttgtgaaaaagggtaaagag cagaatacacagcgaagcttttttctcagaatgaagtgtaccctaactagccgggggaga actatgaacataaagtcagcaacatggaaagtacttcactgcacaggccatattcatgtc tacgataccaatagtaaccaatctcagtgtgggtataagaaaccacccatgacgtgcttg gtgctaatttgtgaacccattcctcatccatcaaatattgaaattcctttagatagcaag acttttctcagtcgtcacagtctggatatgaaattttcttattgtgatgaaagaattact gaattgatgggatatgagccagaagaacttttgggccgctcaatttatgaatattatcat gctttggactctgaccatctgaccaaaactcatcatgatatgtttactaaaggacaagtc accacaggacagtacaggatgcttgccaaaagaggtggatatgtctgggttgaaactcaa gcaactgtcatatataacactaagaactctcaaccacagtgcattgtatgtgtaaattat gttgtgagtggtattattcagcacgacttgattttctcccttcaacaaacagaatgtgtc ctcaaaccagttgaatcttcagatatgaaaatgactcagctattcaccaaagttgaatca gaagatacaagtagtctctttgataaacttaagaaggaacccgatgctttaactttgctg gccccagctgctggagacacaatcatatctttagatttcggcagcaatgacacagaaact gatgaccaacaacttgaggaagttccattgtataatgatgtaatgctcccctcatccaac gacaaattacagaatataaatttggcaatgtctcccttacctgcttctgaaactccaaag ccacttcgaagtagtgctgaccctgcactcaatcaagaagttgcattaaaattagagcca aatccagagtccctggaactttcttttactatgccccagattcaagatcagccagctagt ccttctgatggaagcactagacaaagttcacctgagcctaacagtcccagtgaatattgt tttgatgtggatagtgatatggtcaatgaatttaagctggaattagtagagaaacttttt gctgaagacacagaagcaaagaatccattttccacccaggacactgatttagacttggag atgttagctccttatatcccaatggatgatgacttccagttacgttccttcgatcagttg tcaccactggaaagcagttctacaagccctcagagtgcgagcacagttacagtattccag cctactcaaattcaagagcctcctgttaccactaccagcaccactgctgccactgatgaa ttaaaaacagtgacaaaagatggtacagaagatattaaaatactgattgcatctccatct cctacccatgtacctaaagtaactactagtgccacagcatcaccatacagtgacactgga agtcggacagcctcaccaaacagagcaggaaaaggagtcatagaacagacagaaaaatct catcccagaagccctaacgtgttatcggtcactttgagtcagagaactaccattcctgag gaagaactaaatccaaagatactagctttgcagaatgctcagagaaagcgaaaaatagaa caggacggttcactttttcaagcagtaggaattggaacattattacagcagccagacgat cgtgcaactactacatcactttcttggaaacgcgtaaaaggatgcaaatctagtgaacac aatggaatggagcaaaagacaattattttaataccctctgatttggcatgtagactgctg gggcaatcaatggatgagagtggattaccacaactgaccagttatgattgtgaagttaat gctcctatacaaggcagcagaaacctactgcagggtgaagaattactcagagctttggat caagttaactga

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