Leptonychotes weddellii (Weddell seal): 102738356
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Entry
102738356 CDS
T08708
Symbol
PDE10A
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X5
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
lww
Leptonychotes weddellii (Weddell seal)
Pathway
lww00230
Purine metabolism
lww01100
Metabolic pathways
lww04024
cAMP signaling pathway
lww05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
lww00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
102738356 (PDE10A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
102738356 (PDE10A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
102738356 (PDE10A)
Enzymes [BR:
lww01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
102738356 (PDE10A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
102738356 (PDE10A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
SpoVT_C
HD
DUF7334
Motif
Other DBs
NCBI-GeneID:
102738356
NCBI-ProteinID:
XP_006729814
UniProt:
A0A2U3XEA2
LinkDB
All DBs
Position
Unknown
AA seq
794 aa
AA seq
DB search
MEDGPSNNASCFRRLTECFLSPSLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRK
NNKPEDESAPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNQLLLYELSSIIKIATKAD
GFALYFLGECNNSLCVFTPPGIKEGKPRLIPAGPIAQGTTISAYVAKSRKTLLVEDILGD
ERFPRGTGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCMSHQEVATANLAWA
SVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALF
QVDHKNKELYSDLFDIGEEKEGKPIFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADP
RFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCAL
ALHCANMYHRIRHSECIYRVTMEKLSYHSICTAEEWQSLMRFNLPVRLCKEIELFHFDIG
PFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAI
LQNNHGLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTV
SILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQS
HRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKD
EVPQGQLGFYNAVAIPCYTTLTQIFPPTEPLLKACRNNLSQWEKVIRGEESAVWISSQPG
AHGPSEKLPVKIDD
NT seq
2385 nt
NT seq
+upstream
nt +downstream
nt
atggaagatggaccttctaataatgcgagctgcttccgaaggttgacggagtgtttcctg
agccccagtttgacagatgaaaaagtgaaggcatatctttctcttcatccccaggtgtta
gacgaatttgtatctgaaagtgttagtgcagagactgtagaaaaatggctgaagaggaaa
aacaacaaaccagaagatgaatcggctcctaaggaagtcagcaggtaccaagacacgaat
atgcagggagttgtgtatgaactaaacagctacatagaacaacggttggatacaggagga
gacaaccagctactgctctatgaattgagtagcatcattaaaatagccacaaaagctgat
ggatttgcactgtatttccttggagagtgcaataatagtctgtgcgtgttcactccacct
ggaatcaaggaaggaaaaccccggctcatccctgctgggcccattgcccagggcaccacc
atttctgcctatgtggccaagtccagaaaaacgttgctagtggaagacatccttggggat
gaacgatttccaagaggtactggactggagtcagggactcgcatccagtctgttctttgt
ttaccaattgtcactgcaattggtgacttgattggtatcctcgagctgtatcggcactgg
ggcaaagaagccttctgtatgagtcatcaggaggttgcaacagcaaatctcgcctgggct
tcagtagcaatacatcaggtgcaggtatgcagaggccttgctaaacagactgaattgaat
gacttcctacttgatgtatcaaagacatattttgataacatagtcgcaatagactctcta
cttgaacacataatgatatatgcaaaaaatctggtgaatgccgatcgttgtgcacttttc
caggtagaccataagaacaaggagttatattcagacctttttgatattggagaggaaaag
gaaggaaaacccatcttcaagaagaccaaagaaataagattttccatcgagaaaggaatt
gctggtcaggtagcaagaacaggggaagtcctgaacattccagatgcctatgcagaccca
cgctttaacagggaagtggacctgtacacaggctacaccacccggaatatcctgtgcatg
cccatcgtgagccggggaagcgtgatcggcgtggtgcagatggtgaacaaaataagcggc
agtgccttctcgaaaacggacgaaaacaacttcaagatgtttgccgtcttctgtgcttta
gccttacactgtgccaatatgtatcaccgaatccgtcattccgagtgcatttaccgggtg
actatggagaagctttcctaccatagcatctgtacggcagaggagtggcagagcctcatg
cgcttcaacctccccgtgcgcctctgcaaagaaattgaattattccactttgacattggt
ccttttgaaaacatgtggcctggaatctttgtctacatggtccatcggtcctgtgggaca
tcctgctttgagcttgaaaagttgtgtcgttttattatgtctgtgaagaaaaactatcgg
cgggttccttatcacaactggaaacacgctgtcactgtggctcactgcatgtacgccatt
ctccagaacaaccacgggctcttcaccgaccttgagcgcaaaggactgctaatcgcgtgt
ctgtgtcatgacctggaccacaggggtttcagtaacagctacctgcagaaattcgatcac
cctctggcagctctctattccacttctaccatggagcagcatcacttctcccagacagtg
tccatcctccagttggaagggcacaatatcttctccaccctgagctccagtgaatatgaa
caggtgctcgagatcatccgcaaagctatcattgccacagaccttgctctgtactttgga
aacaggaaacaattggaggagatgtaccagaccggatcgctaaaccttaataatcaatca
catagagatcgtgtcattggtttgatgatgactgcctgtgatctttgttctgtaacaaag
ctgtggccggttacaaaattgacagcaaatgatatatatgcagagttctgggctgagggc
gatgagatgaaaaagttgggaatacaacctattcccatgatggacagagacaagaaggac
gaggtcccacaaggccagctggggttctacaacgccgtggccatcccctgctacaccacc
ctcacccagatcttcccgcccaccgagcctctcctcaaagcgtgcaggaataacctcagc
cagtgggagaaggtgatccgaggggaggagagtgcggtgtggatctcatcccagccaggg
gcccacgggccctcggagaagctgcctgtgaagatcgatgactga
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