Leptonychotes weddellii (Weddell seal): 102738635
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Entry
102738635 CDS
T08708
Symbol
BRCA2
Name
(RefSeq) breast cancer type 2 susceptibility protein
KO
K08775
breast cancer 2 susceptibility protein
Organism
lww
Leptonychotes weddellii (Weddell seal)
Pathway
lww03440
Homologous recombination
lww03460
Fanconi anemia pathway
lww05200
Pathways in cancer
lww05212
Pancreatic cancer
lww05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
lww00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
102738635 (BRCA2)
03460 Fanconi anemia pathway
102738635 (BRCA2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102738635 (BRCA2)
09162 Cancer: specific types
05212 Pancreatic cancer
102738635 (BRCA2)
05224 Breast cancer
102738635 (BRCA2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
lww04121
]
102738635 (BRCA2)
03036 Chromosome and associated proteins [BR:
lww03036
]
102738635 (BRCA2)
03400 DNA repair and recombination proteins [BR:
lww03400
]
102738635 (BRCA2)
Ubiquitin system [BR:
lww04121
]
Ubiquitin ligases (E3)
Multi subunit type E3
BRCC complex
102738635 (BRCA2)
Chromosome and associated proteins [BR:
lww03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Other centrosome duplication proteins
102738635 (BRCA2)
DNA repair and recombination proteins [BR:
lww03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA complex
102738635 (BRCA2)
FA (Fanconi anemia) pathway
Downstream FA components
102738635 (BRCA2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
BRCA-2_helical
BRCA2
BRCA-2_OB3
BRCA-2_OB1
BRCA2DBD_OB2
BRCA2_TR2
Tower
Motif
Other DBs
NCBI-GeneID:
102738635
NCBI-ProteinID:
XP_006729031
UniProt:
A0A2U3XC46
LinkDB
All DBs
Position
Unknown
AA seq
2818 aa
AA seq
DB search
MGESLSHSSIRKNCLQNDSEEPTVSLASSFGTILRKVSNNGTSSNNKTVPQDLDYKETKI
NKEKLQSFITTETDCLSSLQEEPCEDDAKSQRVSDIKEKVLPAVSHPPVPHSEVEGGGIH
FQSPESFSSDHGNTSLLTPSSRDPPSNPVMISRGKESYKMSEKLKCKNHEAGFELTKNIS
MEKNQEIHVLNANSKNAKLLSTEKYVTVASPSMKVQFNQNANLTAIQKDQKEATLISKIA
VSPNSEELFPDDNNFVLEITDESNISGLGNIKELHDSDLCCVREPVLKNSTTVVYTDRDD
KQATKVSIMKDFDSSNIDDLTEKNRNSIKQQLKMTPDQDSKSDITLDIVRKSNGNNDYIN
NWSKLSDPISNHSFGNGFRTASNKEIKLSEHNIRKSKMLFKDIEERYPTNLACIEIVNTS
SLESQKKLSKPLALDPQSINSVSGFVQSSIYVSNSESGHTAPPTLKRDFNSNHNLTPSQK
AEITELSTILEESGSQFEFTQFRKPSHIIQKNPFEMPENQLTVLNSTSEECRDTDLHLTI
NVPSIIQVDSSKKFEGILGGKQKFACLSRTNCNRSASGCLTDKNEVEFRGFYSARGTKLN
VSSEALQKAKKLFSDLDISEETSVEVDTISFSSSKCNDSAVSMIQIEDYNNDKNLNEKNN
KSQLILENNIEMTADIFVEENTEGYKRNTENEDNQYTSASGNTHNLESVGSDSSKNDTVD
IHEEENSLPCIDHNIDLKLSSQFMKEGNTQIKEGLSDLTCLEVARAEDTFHVMSDKQQFT
ANTMRQNIKDFDIFDLSFQTASGKNMRVSKESLNKVINLLDQKWTEEELNNFSDSLNSEL
LSGIDTNKIDISSHEKTENTERKDKIMKASDLTGTENKLLTLQQRPESEIKKIKEPTMLG
FHTASGKKIEIAKESLDKVKNLFDEKEQDNSGITNFSLQGAKMSKDREEYKDGLELACET
IELTTAPKCEEMQNSLEEEKLVSNEVAVAPSLLSDNLYKQTENLKISDRASLKVKVHENI
EKETAKKPTIYINQSTYSAIENSPLAFYAEHGRKISVSEASLFEAKKWLREGELDDQREK
INAAKVICLKEYPDDYVENLSCGNSSSSTITENDKNHLSEKQGPTYLSNSTMSNRYSYHS
DFCHSSEVYNKSEYLSKNKVDTSGIEPVINNVKEGENPSFSEMMSTVREADTDPQIVNED
ICVQKLVTNSSCKNENTPIKVAISDSDNFNSIQKLNPNSNNAVPAYSRASSFVAHQSKVT
EGFTDNCSMVIKQNTKSKSDTHYAKIMAGYPNALDDSEDIIFTNSLDDAEHGSSSHKVFA
DIQSEKTLQLNQSISGLEKVSEIPPCQNNSKTSDICKLSTGKLPKSVSYTNACGIFSTAS
GKSVQVSDAALQKARQVFSKIEDSAKQLFPKVSFKNNEHSDKFANEENAMLHTSQNLLSS
AVFGFSTASGKQVPVSESALCKVKGMLEEFDLIRTECGLQHSSTSRQDVSKIPPPSCIDK
RTPEHCGNSKLEKAYNKFKLSSNCNVESGSSENHCSIKVSPCPSQLKQDKQQLLLGSKVS
LVENVHLLGKEQALPKNTKTEIGKIETFPNLPVKTNTEICSTYSKDPENYLETETVEIAK
AFMEDGELTDSELLSHTKHSLFTRQNTEEMVLLNSRIGKRRGNALVSVGEPPIKRNLLNE
FDRIMKNQEKSLKSSKSTPDGILKDRSLFMHHISLEPITCGPFRTTKERQEMQNPNFTTP
GQEFLSKSHFYEHLALEESSSNLLVSGQPFCTVPATRNEKRRHLNTPGKPVKVFVPPFKT
KSHFHRDEQCISKNTDLEENKQNPKNIDEHGPGDSETNINDSEIHQLKKNNSNQAATIIV
TKCEKEPLDLTSNLQNARDIQDMRIKKKQRQHIFPQPGSLYLAKTSTVPRISLRGAVEGR
VPSACSHKQLYMYGVSRHCVKINSKNAESFQFHTQDYFGKEGLWSGEGIQLADGGWLIPS
NDGKAGKEEFYRALCDTPGVDPNLISRVWVYNHYRWIIWKLAAMEFAFPKEFANRCLSPE
RVLLQLKYRYDVEIDRSRRSAIKKIMERDDTAAKTLVLCISEIISSSTDISETSSGKTSS
VGTRKVGIVELTDGWYAIKAQFDPPLAALVKNGRLTIGQKIVIHGAELVGFPDACTPLEA
PESLMLKISANSTRPARWYAKLGFSPDPRPFPLPLSSLFSDGGNVGCVDVVVQRAYPIQW
MERTLSGICVFRNEREEEKEATKYAEAQQKKLEVLFNKIQGEFEKHDENITKRCIPSCAL
TRQQVCALQDGAELYEAVTNAPDPSYLEGYFSEEQLRALNNHRQMLNDKKQAQIQLEFRK
AMESAEQGEQILSRNVTTVWKLRIISYGKKEKDSVTLSIWRPSSDLYSLLTEGKRYRIYH
LATSQSKSKSEKANIQLTATKKTQYQQLPASDEILFQVYQPREPLYFSKVLDPDFQPPCS
EVDLIGFVVSVVKKIGLAPLVYLSDECHNLLAIKFWADLNEDIIKPHTLIAASNLQWRPE
AKSGIPTLFAGDFSRFSASPKEGHFQQLFHKMKNTIENIGMFCNDAENKLMHILNANAPK
LSTPNKDCASGPHTAQTVLGMGNKFLMSSPSSEMNYQSPSSLCKPKEKFVPTPGSAQMLS
KSYCKGEKEMDDPKSCKKRKALDFLSRLPLPPPVSPICTFVSPAAQKAFQPPRACGTKYE
TPIKKKELNSPQMTPLKFSDLSLLESDSIADEELALINTQALLSGPAGENQLMSLSDSPR
TAPESSKDFLRQKRHSAASGVTGCGSPQARTEERETNVQDASTVKRASMRLQRRQKQK
NT seq
8457 nt
NT seq
+upstream
nt +downstream
nt
atgggggaaagtttatcacattcttctatcagaaaaaactgtttacagaatgattctgaa
gaaccaactgtgtctttagccagctcttttgggacaattctgagaaaagtttccaataat
ggaaccagttctaataataaaacagtacctcaggatcttgattataaagaaacaaaaatt
aataaggaaaaactgcagtcatttataaccacagaaactgattgtctgtcatccttgcag
gaagaaccctgtgaagatgatgcaaaaagtcaaagagtttcagatataaaagaaaaggtc
ttgcctgcagtaagtcaccctcctgtgccacattcagaagtggaaggtggtggtattcac
tttcaatctcccgaaagcttttcatctgaccatggtaataccagtctgttaactcctagc
tccagggatcctccatcaaacccggtcatgatttctagaggaaaagaatcatataaaatg
tcagagaaactaaaatgtaagaatcatgaagctggttttgaattaaccaaaaatatttcc
atggaaaagaatcaagaaatacatgttttaaatgcaaattctaaaaatgctaagctgttg
tcaactgaaaaatatgtaacagtagcatcaccttcaatgaaggtacaattcaaccaaaat
gcaaatctcactgcaatccaaaaagaccaaaaagaagctactttaatttcaaaaatagct
gtcagtccaaactctgaagaacttttcccagatgataataattttgtcttagagataact
gatgaaagtaatatttctggtttaggaaatattaaggaacttcatgattcagatctctgt
tgtgtaagagaacctgttctcaagaactctaccacggtggtgtatacagacagagatgac
aaacaagcgaccaaagtgtcgattatgaaagactttgattcatcaaacatagatgatctt
acagaaaagaacagaaatagcataaagcagcaactaaaaatgactccagatcaagattca
aaatcagacatcaccttggatatagttaggaaatcaaatggaaataatgattacataaat
aattggtcaaaactgtcagatccaatttcaaatcacagttttggaaatggcttcagaaca
gcttctaataaagagataaaactctcggaacacaacattaggaaaagtaaaatgctcttc
aaagatattgaagaacgttatcctactaacttagcatgtattgaaattgtaaatacctca
tcattagaaagtcaaaagaaattaagcaaacctcttgcacttgatccacagtcaattaat
agtgtatctgggtttgtgcagagtagcatatatgtttctaatagtgaaagtggtcacaca
gctcctccaactttaaagcgagattttaattcaaatcataatttaacacctagccaaaag
gcagaaattacagaactttctactattttggaagaatcaggaagtcagtttgaatttaca
cagtttagaaaaccaagccacataatacagaaaaatccatttgaaatgcctgaaaaccag
ctgactgtcttgaatagcacttctgaggaatgcagagatactgatcttcatctcacaatt
aatgtcccatctatcattcaggtagatagcagtaagaaatttgaaggtatacttggaggt
aagcagaagtttgcttgcttgtcgagaaccaactgtaacagaagtgcttctggctgtttg
acagataaaaatgaagtggagtttagaggcttttattctgctcgtggcacaaaactgaat
gttagtagtgaagcattgcaaaaagctaagaagctgttcagtgaccttgatatcagtgag
gaaacttctgtagaagtagatacaataagtttctcctcaagtaaatgtaatgattctgct
gtttcaatgattcagatagaagattataacaatgataaaaatttaaatgagaaaaataat
aaaagccaactaatactagaaaataatattgaaatgactgctgacatttttgttgaagaa
aatactgaaggttacaagagaaatacagaaaatgaagataatcagtatactagtgccagt
ggaaatactcataacttagaatctgttggcagtgattcaagtaaaaatgatacagttgat
attcatgaagaagaaaacagtttgccatgtattgatcacaacatagatctaaaattatct
agccagtttatgaaggagggaaacactcaaattaaagaaggtttgtcagatttaacctgt
ttggaagttgcacgagctgaagatacatttcatgttatgtcagataagcagcagttcaca
gctaatacaatgaggcaaaacataaaagattttgacatttttgatttatcctttcagact
gcaagtgggaaaaatatgagggtctccaaagagtcattaaataaagttataaatctcctt
gatcaaaaatggacagaagaagaattgaataacttttcagattccttgaattctgaatta
ctttctggcatagataccaacaaaatagacatctcaagtcatgagaaaacagaaaatact
gaaagaaaagacaaaataatgaaagcaagtgacctaactggtactgaaaataaattactg
accctccagcaaagaccagaaagtgaaatcaaaaagatcaaagaacctactatgttgggt
ttccatacagctagtgggaaaaaaatagaaattgcaaaggaatctttggacaaagtgaaa
aatctttttgatgaaaaagagcaggataatagtggaatcactaattttagccttcaaggg
gcaaagatgtccaaggacagagaggaatataaagatgggcttgaattagcatgtgagaca
attgaattaacaactgccccaaagtgtgaagaaatgcagaattctttagaggaggaaaaa
cttgtttctaatgaggttgcagtggcacccagcctcttaagtgataatttatacaaacaa
actgaaaatcttaaaatatcagatcgtgcctctctgaaagttaaagtacatgaaaatata
gaaaaagaaacagcaaaaaagcctacaatttatataaatcaatccacttattcagccatt
gaaaattcacctttagcattttacgcagaacatggtagaaaaatttctgtgagtgaagct
tcactgtttgaagcaaaaaaatggcttagagaaggagaattggatgatcaacgagaaaaa
ataaatgctgctaaggtgatctgtttaaaagaatatcctgatgattacgtagaaaatctt
tcatgtggaaatagttcaagtagtaccataactgaaaatgacaaaaatcatctttctgaa
aaacaaggcccaacttatttaagtaatagtaccatgtcaaacaggtattcataccattca
gatttttgtcattccagtgaggtatataataaatcagaatatctttcaaaaaataaagtt
gatacttctggtattgagccagtaataaacaatgttaaggagggagaaaaccctagtttt
tctgaaatgatgtccactgtaagagaagcagacacagacccacaaattgtaaatgaagat
atttgtgttcagaaacttgtgactaactcttcatgcaaaaatgaaaatacacccattaaa
gtggccatatctgactcagataattttaattccattcaaaaactgaatcctaattcaaat
aatgctgtacccgcatacagtagagcaagtagttttgttgcacaccagtcaaaagtgaca
gagggatttacagacaactgcagtatggtaattaagcaaaacaccaagagtaaatcagat
actcactatgcgaaaattatggcaggttatcctaacgcactggatgactcagaggatatt
atttttacaaactctctggatgatgcagaacatggttcatcttcacataaggtttttgct
gacattcaaagtgaaaaaactttacaacttaaccaaagtatatctggattggagaaagtt
tctgaaataccaccttgtcagaataattccaaaacttctgatatatgtaaacttagtaca
gggaagcttcccaagtctgtctcttacacgaatgcttgtgggatttttagcacagcaagt
ggaaaatctgtacaagtatcagatgctgcattacaaaaggcaaggcaggtgttttctaag
atagaagatagtgccaagcaactctttcccaaagtatcatttaaaaataatgaacattca
gacaagttcgcaaatgaagaaaatgctatgctacacacctcccaaaatttactatcatct
gctgtctttggatttagcacagcaagtgggaaacaagttccagtttctgaaagtgcctta
tgcaaagttaagggaatgttagaagaattcgatctgatcagaactgaatgtggtcttcag
cattcatctacatctagacaagatgtatcaaaaatacctcctccctcttgtattgataag
agaaccccagaacattgtggaaactccaaattggaaaaggcctacaataaatttaaatta
tcaagtaactgtaacgttgagagtggttcttcagaaaatcattgctccattaaagtttct
ccatgtccctctcagctgaagcaagacaaacagcaattgctactgggaagcaaagtatct
cttgttgagaacgttcatcttttggggaaagaacaagctttacctaaaaatacaaaaaca
gaaattgggaaaattgaaacttttcctaatcttcctgtgaaaacaaatacagaaatttgt
tctacttactccaaggatccagaaaactatttggaaacagaaacggtagagattgccaaa
gcttttatggaagatggtgagctgacagattctgaactgctaagtcacaccaaacactct
ctttttacacgccaaaacactgaggaaatggttttgttaaattcaagaattggaaaaaga
agaggaaatgcacttgtctcagttggagaacccccaattaaaagaaacttgttaaatgaa
ttcgacaggataatgaaaaatcaagaaaaatccctaaaatcttcgaaaagcactccagat
ggcatcctaaaagacagaagcttgtttatgcatcatatttctttagagccaattacctgt
ggaccctttcgcacaactaaggaacggcaagaaatgcaaaatccaaatttcaccacacct
ggtcaagaatttttgtctaaatctcatttttatgaacacctggctttggaagaatcttca
agcaatttattggtttcagggcagccattctgtacagttcctgccacaagaaatgaaaaa
aggagacacttgaatactccaggcaaaccagtgaaagtctttgtcccaccttttaaaact
aaatcacattttcacagagatgaacagtgtattagcaagaatactgatttggaagaaaac
aaacaaaacccaaaaaacatagatgaacatggccctggtgatagtgaaacaaatattaat
gacagtgaaattcatcagcttaagaaaaataactccaatcaagcagcaacgataatagtc
acaaagtgtgaaaaagaacctttagatttaacttcaaatcttcagaatgccagagatata
caggatatgcggattaaaaagaaacaaaggcagcacatttttccacagccaggtagcctg
tatcttgcaaaaacctccactgtgcctagaatctctctgagaggagcagtggaaggccga
gtcccctctgcgtgttctcataaacagctctatatgtatggcgtttccagacattgtgta
aaaattaacagcaaaaatgcagaatcttttcagtttcacactcaggattattttggtaag
gaaggactatggtctggagagggaatacagttggctgatggtggatggctcataccctcc
aatgatggaaaggctggaaaagaagaattttatagggctctgtgcgacaccccaggtgtg
gatccaaatcttatttctagagtttgggtgtataatcactacagatggattatatggaag
ctggcagctatggaatttgcctttcctaaggaatttgctaataggtgcctaagcccagaa
agggtgcttcttcaactaaaatacagatatgatgtggaaattgatagaagcagaagatca
gctataaaaaagataatggaaagggatgacacagctgcaaaaacacttgttctctgtatt
tctgaaataatttcatcaagcacagatatatctgaaacttccagcggtaaaactagcagt
gtgggtaccagaaaagtgggcattgtcgagctcacggatggatggtatgctattaaggcc
cagtttgatcctcccctagcagctctcgtaaagaacggtagactgaccatcggtcagaag
atcgttattcatggggcagaactggtgggctttcctgatgcctgcacaccgctcgaagcc
ccagaatctcttatgttaaagatttctgctaacagtactcgtcctgctcgctggtatgcc
aaacttggattctctcctgatcctaggcctttccctctccccttgtcatcacttttcagt
gatggaggaaatgttggttgtgttgatgtagttgttcaaagagcatacccaatacagtgg
atggagaggaccctatctggaatatgcgtatttcggaatgaacgagaggaagaaaaggag
gcaacaaaatatgcagaagcccaacaaaagaaactagaagtcttattcaataaaattcaa
ggggaatttgaaaagcacgacgaaaatataacaaaacgatgtataccatcatgtgcatta
acaagacagcaagtctgtgctctgcaagatggtgcagagctttatgaagcagtgacgaat
gcaccagacccgagttatctggagggttactttagtgaagagcagttaagagccttgaat
aatcacagacagatgttgaatgataagaagcaagcacagatccagttggaattcaggaag
gctatggaatctgctgagcaaggagaacaaattttatcaaggaatgttacaaccgtgtgg
aagttgcgtatcataagctatgggaaaaaagaaaaagattcagttacactgagtatctgg
cgtccatcatcagatttatattccctgttaacagaaggaaagagatacagaatctatcat
cttgcaacatcacaatctaaaagtaaatctgaaaaagctaacatacagctaacagcaaca
aagaaaacccagtatcaacaactaccggcttcagatgaaatcctattccaagtttatcag
ccgagggagcccctttacttcagcaaagtattggatccagacttccaaccaccttgttct
gaggtggacctaataggatttgtagtttctgttgtgaaaaaaataggtcttgctcctttg
gtctatttgtcagatgaatgccataatttattggcaataaagttttgggccgaccttaac
gaggacattattaaacctcacacattaattgctgcaagcaacctccagtggcgaccagaa
gccaaatcaggaattcctactttatttgctggagatttttccaggttttctgccagtcca
aaggagggccattttcaacagctattccacaaaatgaaaaacactatcgagaatattggt
atgttttgcaatgatgcagaaaacaaacttatgcatatacttaatgcaaatgctcccaag
ttgtccaccccgaataaagactgtgcttcagggccacacactgctcaaacagtccttggc
atgggaaataaatttctgatgtcttctcccagtagtgagatgaattaccagagtccttca
tcactttgtaagccaaaagagaagtttgttcccacacctggatcagcccaaatgctttca
aagtcttattgtaaaggggagaaagagatggatgacccaaaaagctgcaagaagagaaaa
gctttggattttttgagtagactgcctttacctccacctgtcagtcccatttgtacattt
gtttctccagctgcacagaaggcctttcagccaccacgggcttgcggcaccaaatacgaa
acacctataaagaagaaagagttgaattctcctcagatgactccacttaaatttagtgac
ctttcccttttggaaagtgattcaatagcagacgaagaactcgcattgataaacactcaa
gcccttttgtcaggtccggcaggagaaaatcaacttatgtctctcagtgactcccctagg
actgctcctgagagctcaaaggattttctgaggcagaaaaggcattctgctgcatctggg
gtcacaggatgcgggagcccccaggcccgcaccgaagagcgggagaccaatgtgcaggac
gcaagtacagtgaaaagggcatctatgagactgcaaaggcgacaaaaacaaaaatga
DBGET
integrated database retrieval system
