Leptonychotes weddellii (Weddell seal): 102739354
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Entry
102739354 CDS
T08708
Symbol
HUWE1
Name
(RefSeq) E3 ubiquitin-protein ligase HUWE1
KO
K10592
E3 ubiquitin-protein ligase HUWE1 [EC:
2.3.2.26
]
Organism
lww
Leptonychotes weddellii (Weddell seal)
Pathway
lww04120
Ubiquitin mediated proteolysis
lww04137
Mitophagy - animal
Brite
KEGG Orthology (KO) [BR:
lww00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
102739354 (HUWE1)
09140 Cellular Processes
09141 Transport and catabolism
04137 Mitophagy - animal
102739354 (HUWE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
lww04121
]
102739354 (HUWE1)
Enzymes [BR:
lww01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
102739354 (HUWE1)
Ubiquitin system [BR:
lww04121
]
Ubiquitin ligases (E3)
HECT type E3
102739354 (HUWE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
DUF913
DUF908
WWE
UBA_7
UBA
WWE_5
Motif
Other DBs
NCBI-GeneID:
102739354
NCBI-ProteinID:
XP_030880272
UniProt:
A0A7F8QGB4
LinkDB
All DBs
Position
Unknown
AA seq
3267 aa
AA seq
DB search
MKVDRTKLKKTPTEAPADCRALIDKLKVCNDEQLLLELQQIKTWNIGKCELYHWVDLLDR
FDGILADAGQTVENMSWMLVCDRPEREQLKMLLLAVLNFTALLIEYSFSRHLYSSIEHLT
TLLASSDMQVVLAVLNLLYVFSKRSNYITRLGSDKRTPLLTRLQHLAESWGGKENGFGLA
ECCRDLHMMKYPPSATTLHFEFYADPGAEVKIEKRTSSNTLHYIHIEQLDKISESPSEIM
ESLTKMYSIPKDKQMLLFTHIRLAHGFSNHRKRLQAVQARLHAISILVFISPFAVYSNAL
QESANSILYNGLIEELVDVLQITDKQLMEIKAASLRTLTSIVHLERTPKLSSIIDCTGTA
SYHGFLPVLVRNCIQAMIDPSMDPYPHQFATALFSFLYHLASYDAGGEALVSCGMMEALL
KVIKFLGDEQDQITFVTRAVRVVDLITNLDMAAFQSHSGLSIFIYRLEHEVDLCRKECPF
VIKPKIQRPSTTQEGEEMETDMDVADVTMETSPGSSISMEHRLDVELRASSSSSSTSLSS
GSGPGPRPGVQCIPQRAALLKSMLNFLKKAIQDPAFSDGIRHVMDGSLPTSLKHIISNAE
YYGPSLFLLATEVVTVFVFQEPSLLSSLQDNGLTDVMLHALLIKDVPATREVLGSLPNVF
SALCLNARGLQSFVQCQPFERLFKVLLSPDYLPAMRRRRSSDPLGDTASNLGSAVDELMR
HQPTLKTDATTAIIKLLEEICNLGRDPKYICQKPSIQKADGTATAPPPRSNHAAEEASSE
DEEEEEVQAMQSFNSTQQNETEPNQQVVGTEERIPIPLMDYILNVMKFVESILSNNTTDD
HCQEFVNQKGLLPLVTILGLPNLPIDFPTSAACQAVAGVCKSILTLSHEPKVLQEGLLQL
DSILSSLEPLHRPIESPGGSVLLRELACAGNVADATLSAQATPLLHALTAAHAYIMMFVH
TCRVGQSEIRSISVNQWGSQLGLSVLSKLSQLYCSLVWESTVLLSLCTPNSLPSGCEFGQ
ADMQKLVPKDEKAGTTQGGKRSDGEQDGAAASMDASTQGLLEGIGLDGDTLAPMETDEPT
ASDSKGKSKITPAMAARIKQIKPLLSASSRLGRALAELFGLLVKLCVGSPVRQRRSHHAA
STTTAPTPAARSTASALTKLLTKGLSWQPPPYTPTPRFRLTFFICSVGFTSPMLFDERKY
PYHLMLQKFLCSGGHNALFETFNWALSMGGKVPVAEGLEHSDLPDGTGEFLDAWLMLVEK
MVNPTTVLESPHSLPAKLPGGVQNFPQFSALRFLVVTQKAAFTCIKNLWNRKPLKVYGGR
MAESMLAILCHILRGEPVIRERLSKEKEGSRGEEDTGQEEGGSRREPQVNQQQLQQLMDM
GFTREHAMEALLNTSTMEQATEYLLTHPPPIMGGVVRDLSMSEEDQMMRAIAMSLGQDIP
MDQRAESPEEVACRKEEEERKAREKQEEEEAKCLEKFQDADPLEQDELHTFTDTMLPGCF
HLLDELPDTVYRVCDLIMTAIKRNGADYRDMILKQVVNQVWEAADVLIKAALPLTTSDTK
TVSEWISQMATLPQASNLATRILLLTLLFEELKLPCAWVVESSGILNVLIKLLEVVQPCL
QAAKEQKEVQTPKWITPVLLLIDFYEKTAISSKRRAQMTKYLQSNNNNWRWFDDRSGRWC
SYSASNNSTIDSAWKSGETSVRFTAGRRRYTVQFTTMVQVNEETGNRRPVMLTLLRVPRL
NKNSKNSNGQELEKTLEESKEMDIKRKENKANDTPLALESTNTEKETSLEETKVGEILIQ
GLTEDMVTVLIRACVSMLGVPVDPDTLHATLRLCLRLTRDHKYAMMFAELKSTRMILNLT
QSSGFNGFTPLVTLLLRHIIEDPCTLRHTMEKVVRSAATSGAGSTTSGVVSGSLGSREIN
YILRVLGPAACRNPDIFTEVANCCIRIALPAPRGSGTASDDEFENLRIKGPNAVQLVKTT
PLKPSPLPVIPDTIKEVIYDMLNALAAYHAPEEAEKSDPKPGGMTQEVGQLLQDMGDDVY
QQYRSLTRQSSDFDTQSGFSINSQVFAADGASTETSTSGTSQGEASTPEESRDGKKEKEG
DRASEEGKQKGKGSKPLMPTSTILRLLAELVRSYVGIATLIANYSYTVGQSELIKEDCSV
LAFVLDHLLPHTQNAEDKDTPALARLFLASLAAAGSGTDAQVALVNEVKAALGRALAMAE
STEKHARPPRPSLSSFCRQVFPSHFTQQRTKETNCESDRERGSKQACSPCSSQSTSSGIC
TDFWDLLVKLDNMNVSRKGKNSVKSVPVSAGGEGETSPYSLEASPLGQLMNMLSHPVIRR
SSLLTEKLLRLLSLISIALPENKVSEAQANSGSSASSTTVATSTTSTTTTTAASSTPTPP
AATTPVTSAPALVAATAISTIAVAASTTVTTPTTATTTVSTSAATKASKSPAKLGDGGSS
SADFKMVSSGLTENQLQLSVEVLTSHSCSEEGLEDAANVLLQLSRGDPATRDTVLKLLLN
GARHLGYTLCKQIGTLLAELREYNLEQQRRAQCETLSPDGLPEEQPQTTKLKGKMQSRFD
MAENVVIVASQKRPLGGRELQLPSMSMLTSKTSTQKFFLRVLQVIIQLRDDTRRANKKAK
QTGRLGSSGLGSASSIQAAVRQLEAEADAIIQMVREGQRARRQQQAATSESSQSEASVRR
EESPMDVDQPSPSAQDTQSIGSDGTPQGEKEERPPELPLLSEQLSLDELWDMLGECLKEL
EESHDQHAVLVLQPAVEAFFLVHATERESKPPVRDTRESQLAHIKDEPPPLSPAPLTPAT
PSSLDPFFSREPSSMHISSSLPPDTQKFLRFAETHRTVLNQILRQSTTHLADGPFAVLVD
YIRVLDFDVKRKYFRQELERLDEGLRKEDMAVHVRRDHVFEDSYRELHRKSPEEMKNRLY
IVFEGEEGQDAGGLLREWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYF
KFVGRIVAKAVYDNRLLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVST
LGYDLTFSTEVQEFGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFL
EGFYEIIPKRLISIFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRS
FDQADRAKFLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDL
PAYESFEKLRHMLLLAIQECSEGFGLA
NT seq
9804 nt
NT seq
+upstream
nt +downstream
nt
atgaaagtagacaggactaaactgaaaaagacacctactgaggctcctgcagactgcaga
gccttaatagacaaactcaaagtttgtaatgatgagcaactcctcttggaactgcagcag
atcaaaacatggaacattgggaagtgtgagttataccactgggtggatctgttggaccgc
tttgatggaatcctggcagatgctggacaaacagtggagaatatgtcgtggatgctcgta
tgtgataggccggaaagagaacaactgaaaatgcttctcttggctgtgttgaacttcaca
gccttgctcattgagtacagcttttcccggcatctgtacagttccatagagcatttgaca
actttattggcttcctctgatatgcaagtggtgctggcagtccttaatcttctctatgta
tttagcaaaagatcaaactatatcacacgccttggatctgacaagagaaccccactgcta
acccggctacaacacttggcagagagctggggtggaaaggagaatggctttggacttgca
gaatgttgcagagacttgcatatgatgaaatacccacccagtgcaactacactacacttt
gaattctatgcagaccctggggccgaggtcaaaatcgagaaaaggacaagtagtaacaca
ctacattatattcacatagagcaacttgacaagatttcagaaagcccttctgaaatcatg
gaatctcttaccaaaatgtacagcattcctaaggataagcagatgctgttatttacacac
atacggctggcccatggcttttctaatcacaggaaacgattgcaagctgttcaagccagg
ctgcatgcaatatctatattagtgtttatttctccttttgcagtgtattccaatgccttg
caggagtcagcaaacagtatcttgtataatgggttgatagaggagttggtagatgtcctt
cagataacagataagcagcttatggagattaaagctgcttctttacgaacattaacatca
attgtccacttggagagaactcccaaactcagcagtattattgactgtactggaactgcc
tcttaccatggatttttgccggtacttgtgcggaactgtatccaggccatgattgatcct
tccatggatccgtaccctcaccagtttgccactgctctcttctcttttttataccatctg
gccagctacgatgctggtggtgaagccttggtctcctgtggaatgatggaagccttattg
aaggtcataaagtttcttggtgatgaacaggaccagataacatttgtcaccagagctgtc
agagtggttgacctcatcaccaacctggacatggcagcttttcaatcccatagtggactt
tctatcttcatttatagacttgagcatgaagtagatttgtgtcgaaaagaatgtccattt
gtgatcaagccaaagatccagagacccagtactacacaagaaggagaagaaatggaaact
gatatggatgttgcagatgtgactatggaaactagtccaggctcatccatctctatggag
caccggctagatgttgaattaagggcatcaagttctagtagcagcactagcctctcctct
ggctctggccctggcccccgtcctggagtccagtgtattccacaaagagcagcacttctc
aaatccatgttgaatttcctcaagaaggccattcaagaccctgctttctcagatggcata
cgacatgtgatggatggttctctccctacctccctgaagcacatcatcagtaatgcagaa
tactatggcccatcactcttcctcctagctactgaagtggtgactgtgtttgtatttcaa
gaaccatcactgctatcctcactccaggacaatggattaacagatgtcatgcttcatgca
ctgcttatcaaagatgttcctgctacccgtgaagtccttggctccctcccaaatgtattc
agtgcactctgcttgaatgcccgaggtcttcaatcatttgtacagtgtcagccttttgaa
cgtcttttcaaagttcttctgtctccagattacctcccagccatgcgaaggaggaggagt
tctgatcctcttggggatactgcatctaacctggggagtgctgttgatgagctcatgaga
catcagcccaccctcaaaacagatgcaacgactgcgatcatcaagttacttgaagaaatc
tgtaatcttggaagagaccctaaatacatctgtcagaagccatcaatccagaaggcagat
ggcactgccactgctcctcctccaaggtctaatcatgctgcagaagaggcctctagtgag
gatgaggaggaagaagaagtacaggccatgcagagctttaattctacccaacagaatgaa
accgagcctaatcagcaggttgttggtacagaggaacgtattcctattcccctcatggat
tacatccttaatgtgatgaaatttgtggaatctattctgagcaacaatacaacagatgac
cactgccaggaatttgtgaatcagaaaggactcttgcctttggttaccattttgggtctt
cccaatctgcccattgactttcccacatctgcggcttgtcaggctgttgcaggtgtctgc
aaatccatattgacactgtcacatgaacccaaagtccttcaggagggtctccttcagttg
gactccatcctttcatccttggagcccttacaccgcccaattgaatcccctggaggctca
gtgttattgcgagaactggcttgtgctggcaatgttgctgatgctaccctctcagctcag
gccacacctctactgcatgcactcactgctgcccatgcctacatcatgatgtttgttcat
acttgcagagttggacagagtgaaattcgttccatctccgtaaaccagtggggctctcag
ttgggtctgagtgttctgagcaagctgagccagttatactgttccctggtgtgggaaagc
acagtccttctctccctgtgtaccccaaacagcctaccatctgggtgtgaatttggccag
gcagacatgcagaaactggttccaaaggatgagaaggcaggtacgacccagggcggaaaa
agatcagatggggaacaggatggagcagctgcaagtatggatgcttctacccagggctta
ttagaaggcattggacttgatggtgacacattggctcccatggagacagatgaacctact
gcttcagactctaaaggcaaatctaaaatcacacctgctatggctgcaagaatcaagcag
atcaagcctttattgtcagcatcctccagattaggccgagcgctcgctgagctttttgga
ctccttgttaaactttgtgtggggtctcctgtccgccagagaaggagccatcatgctgcc
agcaccaccacagcaccaacacctgctgctcgatccacagcctcagccctcactaagctc
ctcacaaagggcttgtcttggcagcctccaccatatacacctactccccgcttcaggctg
acattcttcatctgttcagttggttttacatccccaatgctgtttgatgagaggaagtat
ccctaccacctcatgctgcagaaatttctctgctctggaggccacaatgctctttttgaa
actttcaattgggctctgtccatgggaggcaaagttcctgttgctgagggattagagcat
tcagatttacctgatggcacaggagaattcctagatgcctggctaatgctagtggagaag
atggtgaatcccaccacggtgcttgaatctccacattcactgcctgccaaattgcctgga
ggtgtccagaactttccacaattcagtgccctccgcttccttgtggtaactcagaaagca
gcctttacttgcatcaagaacctgtggaatcggaagcccctgaaggtatatggcgggcga
atggctgagtccatgctggctatcctatgccacatcctccgaggagaacctgtgattcga
gagagactgagcaaagagaaggagggatctcgaggagaagaggacacagggcaagaggaa
ggtggctctcgccgagaacctcaagtcaaccagcagcaactgcaacagctcatggacatg
ggtttcacaagggaacatgccatggaggccctgttgaacaccagcaccatggagcaggcc
acagagtaccttctaacccatcctcccccaatcatgggaggagttgttcgggatctgagt
atgtccgaagaggaccagatgatgagagcaattgccatgtctctaggacaggatatccca
atggatcaaagagcagagtcacctgaggaagttgcttgtcggaaggaagaggaggaacgg
aaagctcgggaaaagcaggaagaggaagaagctaaatgtctagagaagttccaggatgct
gatccattggaacaagatgagctccacacattcacagataccatgttgccaggctgcttt
caccttcttgatgagctgccggacacagtgtaccgggtgtgtgatctgatcatgaccgca
atcaaacgtaatggagctgactatcgagatatgattctcaagcaagtagtcaatcaggta
tgggaagctgccgatgtattgatcaaagctgctcttcccctgacaacaagtgacacaaaa
actgtgtcagagtggatcagtcagatggccaccctgccccaggcttccaacttggctact
agaatcttgcttttaacactgctttttgaggagttgaagctaccttgtgcctgggtcgtt
gaatcaagtggcatccttaatgtcctaatcaaactcttggaagtagttcagccctgccta
caggccgctaaggagcaaaaggaggtccagaccccaaagtggatcaccccagtgttgctc
ctgatagatttctatgaaaagacagccatttcctctaaaagaagagcccaaatgactaag
tatctacagtccaacaacaacaactggcgctggtttgatgaccgctctgggcgttggtgt
agttacagtgcaagcaacaacagcactattgattctgcctggaaatctggagagacaagt
gtgcgtttcactgcaggccgaagaagatacactgtccagttcactacaatggtgcaggtt
aatgaagaaacagggaaccggcgccctgtgatgttgactctcctgagggtaccacggctg
aataaaaactcgaaaaatagcaatggacaagagctagagaagacactggaagaaagcaaa
gaaatggatatcaaacgtaaagaaaataaagccaatgatactcctttggccctagagagt
acaaatactgaaaaggagacgagcctggaagaaacaaaagttggggagatcctgatccag
ggcctgacagaggatatggtgactgttttaatccgggcctgcgtgagcatgctaggagtc
cctgtggacccagacactttgcatgccacccttcgcctctgcctgaggctcacccgagac
cacaaatacgccatgatgtttgcagagctgaagagtacccgcatgatcttgaatttgacc
cagagctcaggcttcaatgggtttactcccctggtcacccttctcttaagacacatcatt
gaggacccctgcaccctccgtcataccatggaaaaggtggttcgctcagcagctacaagt
ggagctggtagcacgacctctggtgttgtatccggcagccttggttctcgggagatcaac
tacatccttcgtgtccttgggccagctgcatgccgcaatccagacattttcacagaagta
gccaactgctgtatccgcattgcccttcctgcccctcgaggctcaggaactgcttccgat
gatgaatttgagaaccttagaattaaaggtcctaatgctgtacagctggtgaagacaacc
cctttgaagccctcgcctctgcctgtcattcctgatactatcaaggaagtgatctatgat
atgctgaatgccctggctgcataccatgctccagaggaagcagagaaatctgaccctaaa
cctgggggtatgacccaagaggttggccaactcctacaagacatgggggatgatgtatac
cagcagtaccggtcacttactcgtcagagcagtgactttgatacacagtcaggtttttcc
attaatagtcaggtctttgctgcagatggtgcctccactgagacttccacatctgggaca
tcccaaggagaagcatcaactccagaggagtctcgggatgggaagaaagagaaagaaggg
gaccgggcctctgaggaaggcaagcagaaaggcaagggcagcaaacctttaatgcccacc
tccactattcttcgtcttctggcagagttggtgaggtcctatgttggtattgctaccctg
attgccaactacagctacactgtgggccagtctgagctgatcaaagaggactgcagtgtg
ctagcttttgttctggaccacctcctcccacatacccagaatgcagaagacaaggacaca
cctgccctggcccgcctattcctcgcaagcctggctgctgcagggagtggcacagatgcc
caagtggcccttgtgaatgaagtaaaagcagccctgggacgggcactggctatggctgag
agtacagagaaacatgccagaccccctagaccaagcctgtcctccttttgccggcaggta
tttcccagccactttacacagcagcggaccaaagaaacaaactgtgagagtgatcgggag
aggggcagtaagcaggcctgcagcccatgctcttcacagtccaccagcagtggcatttgc
acagacttctgggacttattggtaaaactggacaacatgaatgtcagtcggaaaggcaag
aactccgtgaagtcagtgccagtgagcgctggtggtgagggggaaacctccccatacagc
ctcgaggcctctccactggggcagctcatgaacatgttgtcacacccagtcatccgccgg
agctctctcttaactgagaaactcctcagactcctttctctcatctcaattgctctccca
gaaaacaaagtgtcggaagcacaggctaattctggcagcagtgcttcctccaccactgtt
gccacctcaaccacatctaccaccactaccactgccgcctccagcacgcccactccccct
gctgcaaccacccctgtcacttctgctccagctctggtcgctgccacggctatatccacc
attgccgtagctgcttcgaccacggtgactacccccacgactgctaccactactgtttca
acttctgcagctactaaggccagcaaatctccagcaaagttgggtgatgggggcagcagc
agtgcagactttaagatggtatcctctggccttactgaaaaccagctacagctctctgtg
gaggtgctgacatcccactcttgttctgaagaaggtctagaggatgcagccaatgtgtta
ctgcagctctctcggggggaccctgcgacccgggacactgttctcaagctgctactgaat
ggagctcgccatctgggttatactctttgtaaacagataggtacccttctggctgagtta
cgggaatacaacctagaacagcagcgaagagcccagtgtgagaccctctctcctgatggc
ctgcctgaggagcagccacagaccaccaagctaaaaggcaaaatgcagagcaggtttgac
atggctgagaatgtggtaattgtggcatctcagaagcgacctctgggtggccgggagctc
cagctgccttctatgtccatgttgacatccaagacgtctacccagaagttcttcttgaga
gtactgcaggtcatcatccagctccgggacgacacacgccgagctaacaagaaagccaag
cagacaggcaggctaggttcttccggtttaggctcagctagcagcatccaggcagctgtt
cggcagctggaggctgaggctgatgccattatacaaatggtacgtgagggtcaaagggcg
cggagacagcaacaagcagcaacgtcggagtcaagccagtcggaagcctctgtccggagg
gaggagtcacccatggatgtagaccagccatctcccagtgctcaggatactcagtccatt
ggctcagatggaaccccacaaggggagaaggaggagaggccacctgagttacccctgctc
agtgagcagctgagcttggacgagctatgggacatgctgggagagtgtctaaaggaactg
gaggaatcccatgaccagcatgcggtgctagtgctacagcctgctgtcgaggccttcttt
ctggtccatgccacagagcgggagagcaagcctcctgttagagacacccgtgagagccag
ctggcacacatcaaggacgaacctcctccactctcccctgcccccttaaccccagctact
ccttcctcccttgacccattcttctccagggagccctcatctatgcacatctcctcaagc
ctgccccctgacacacagaagttccttcgctttgcagagactcaccgcactgtgttaaac
cagatcctacggcagtccaccacccacctcgctgatggaccttttgctgtcctggtagac
tacattcgtgtcctcgactttgatgtcaagcgcaaatatttccgccaagagctggaacgt
ttggatgagggactccggaaagaagacatggctgtgcatgtccgccgtgatcatgtgttt
gaagactcctatcgtgaactgcaccggaaatcccctgaagaaatgaagaatcgattgtat
atagtgtttgaaggagaagaagggcaggatgctggagggctcctgcgggagtggtatatg
atcatctctcgggagatgtttaaccctatgtatgccttgttccgtacctcacccggtgat
cgggtcacctacaccatcaacccatcttcccactgcaaccccaaccacctcagctacttc
aagtttgttggacgcattgtggccaaagctgtatatgacaaccgcctcctggagtgctat
tttactcggtccttctacaaacacatcttgggcaagtctgtcagatacacggatatggag
agtgaagattaccacttctaccagggcctggtttatctgctggaaaatgacgtctccaca
ctaggttatgacctcaccttcagcactgaggtccaagagtttggagtctgtgaagttcgt
gacctcaaacccaatggggccaacatcttggtaacagaagagaataagaaggaatatgta
cacctggtgtgccagatgaggatgacaggagccatccgtaaacagctggcagctttctta
gaaggcttctatgagatcattccaaagcgcctcatttctatcttcactgagcaggagtta
gagctgctcatatcaggactgcccacaatcgacattgatgatttgaaatccaacactgaa
taccacaagtaccagtccaactctattcagatccagtggttctggagagcattgcgttct
ttcgaccaagctgaccgtgccaagttcctccagtttgtcacaggtacttccaaggtgccc
ttgcaaggctttgctgcccttgaaggcatgaatggcattcagaagtttcagatccatcga
gatgacaggtccacagatcgcctgccttcagctcacacatgttttaatcagctggacctg
cctgcctacgagagctttgagaagctccgccacatgctactattggccatccaggagtgc
tctgaaggctttgggctggcctaa
DBGET
integrated database retrieval system
