Leptonychotes weddellii (Weddell seal): 102739386
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Entry
102739386 CDS
T08708
Symbol
NOTCH3
Name
(RefSeq) neurogenic locus notch homolog protein 3
KO
K20995
Notch 3
Organism
lww
Leptonychotes weddellii (Weddell seal)
Pathway
lww01522
Endocrine resistance
lww04330
Notch signaling pathway
lww04371
Apelin signaling pathway
lww04658
Th1 and Th2 cell differentiation
lww04919
Thyroid hormone signaling pathway
lww05165
Human papillomavirus infection
lww05200
Pathways in cancer
lww05206
MicroRNAs in cancer
lww05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
lww00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
102739386 (NOTCH3)
04371 Apelin signaling pathway
102739386 (NOTCH3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
102739386 (NOTCH3)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
102739386 (NOTCH3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102739386 (NOTCH3)
05206 MicroRNAs in cancer
102739386 (NOTCH3)
09162 Cancer: specific types
05224 Breast cancer
102739386 (NOTCH3)
09172 Infectious disease: viral
05165 Human papillomavirus infection
102739386 (NOTCH3)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
102739386 (NOTCH3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
EGF
hEGF
EGF_TEN
EGF_CA
EGF_2
Ank_2
Ank
Notch
NODP
Ank_4
NOD
Ank_3
Ank_5
EGF_3
EGF_Teneurin
cEGF
JAG1-like_EGF2
Motif
Other DBs
NCBI-GeneID:
102739386
NCBI-ProteinID:
XP_030886809
UniProt:
A0A7F8R0F8
LinkDB
All DBs
Position
Unknown
AA seq
2238 aa
AA seq
DB search
LPPARALPLLLLLAGPGAAAPPCLDGSPCMNGGRCTQLPSREAACLCPPGWVGERCQLED
PCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCTHGARCSVGPDG
RYICSCPPGYQGRSCRSDVDECRVGGPCRHGGTCLNTPGSFRCQCPAGYTGPLCENAAVP
CAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNC
QCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCAT
AVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCP
PGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPC
RNQATCLDRIGQFTCICMAGFTGTYCEVDMDECQSSPCVNGGVCKDRVNGFSCTCPSGFS
GAMCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCERNVDDCSPDPCHHGRCV
DGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPPGTTGVNCEVN
IDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGDGGSCMDGENGFH
CLCPPGSLPPLCLPPSHPCAQEPCSHGVCHDAPGGFRCVCEPGWSGPRCSQSLARDACES
QPCQSGGTCTSDGMGFHCTCPPGVQGRQCELPSPCAPNPCEHGGHCESAPGQLPVCSCPP
GWQGPRCQQDVDECAGPSPCGSHGTCTNLEGSFSCTCHRGYSGPSCDQDIDDCDPNPCLN
GGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSSPCGPGTCTDHVASFTCTCPPGYGGFH
CEQDLPDCSPSSCFHGGTCVDGVSSFRCQCRPGYTGAHCQHEADPCLSRPCLHGGVCTAA
HPGFRCTCPEGFTGTQCQTLVDWCSRAPCQNGGRCAPTGATFYCLCPPGWSGRLCDIRSV
PCREAAAQLGVRLEELCQTGGRCVDKDNSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGT
CRGYVGGYVCECPAGYTGDNCEDDVDECASQPCQHGGFCIDLVARYLCSCPPGTLGVLCE
INEDDCGPGPPLDQGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECHPGACHDAH
TRDCLQDLGGGFRCICRAGFTGPRCQTVLSPCESQPCQHGGQCRPSPGPGGVLTFTCHCI
PPFWGPRCERVARSCRELQCPAGVPCQQTVRGPRCACPPGLSGPACRACEAKSGDKRCDR
ECNSPGCGWDGGDCSLSVGDPWRQCAALQCWRLFNNSRCDPACSSPACLYDNFDCRAGGR
ERACNPVYEKYCADHFADGRCDQGCNTEECGWDGLDCAGEVPALLARGVLVLTVLLPPEE
LLRSSADFLQRLSGILRTSLRFRLDEHGQAMVFPYHRPGPGSESRNRRELAPEVIGSVVM
LEIDNRLCLQSPENDHCFPDAQSAADYLGALSAVERLDFPYPLRAVRGEPLELPEPSVPL
LPLLAASAVFLLVILVLGVMVARRKREHSTLWFPEGFALHKDVAAGHKGRREPVGQDALG
MKNMAKSESLMGEVATDWMDTECPEAKRLKVEEPCVGAEDAVDCRQWTQHHLVAADIRVA
PAMALTPPQGDVDADGMDVNVRGPDGFTPLMLASFCGGALEPMPTEEDEAEDTSASIISD
LICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTAD
AQGVFQILIRNRSTDLDARMADGSTALILAARLAVEGMVEELIASHADVNAVDELGKSAL
HWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHFANREITDH
LDRLPRDVAQERLHQDIVRLLDQPSGPRSPHGPHGLGPLLCPPGAFLPGLKVAQSGGKKS
RRPPGKTGLGPQGTRGRGKKLTLACPGPLAESSVTLSPVDSLDSPRPFGGPPASPGGFSL
EGPYAAATATAVSLAQIGGAGRAGLGRQPPGGCVLSLGLLNPVAVPLDWARLPPPAPPGP
SFLLPLAPGPQLLNPGTPVSPQERPPPYLAAPGHAEEYPAAGAHGSPPKARFLRVPSEHP
YLTPSPESPEHWASPSPPSLSDWSDSTPSPATATGPTATAAGALPAQPLPLSVPGPLAQA
QTQLGPQPEVTPKRQVLA
NT seq
6717 nt
NT seq
+upstream
nt +downstream
nt
ctgccgcccgcgcgggcgctgcccctgttgctactgctagcggggcccggggctgcagca
cccccttgcctggacgggagcccgtgtatgaatggaggtcgctgcacccagctgccctcc
cgggaggctgcctgcctgtgcccaccaggatgggtgggcgagcggtgccagctggaagac
ccctgccattcgggcccctgtgctggccggggcgtctgccagagctccgtggtggcaggc
accgcccggttctcctgccgctgcccccgtggcttccgaggtcccgactgctccctgccg
gacccctgcctcagcagtccctgtacccatggtgcccgctgctcggtggggcccgatggc
cgctacatctgctcctgcccacctggctaccagggccgcagctgccgaagcgatgtggat
gagtgccgggtgggagggccctgccgccatggtggcacctgcctcaacacgcctggttcc
ttccgctgccagtgcccagctggctacacggggccactgtgtgagaacgctgcggtgccc
tgcgccccctcgccgtgccgtaacgggggcacatgtagacagagtggcgatctcacctat
gactgcgcctgccttcctgggttcgagggccagaactgtgaagtgaatgtggacgactgt
ccaggacaccgatgtctaaatggggggacatgtgtggatggcgtcaacacctacaactgc
cagtgccctcctgaatggacaggccaattctgcacggaggacgtggacgaatgtcagctg
cagcccaacgcttgccacaatgggggcacctgcttcaacactctgggtggccacagctgt
gtgtgtgtcaatggctggacaggcgagagctgcagtcagaatatcgatgactgcgccacg
gctgtgtgcttccatggggccacctgccatgaccgtgtggcctcgttctactgtgcctgt
cccatgggcaagactgggcttctgtgtcatctggatgacgcctgcgtcagcaacccctgt
cacgaggatgctatctgcgacacgaaccccgtgaatggccgggccatctgcacctgtcca
ccaggcttcaccggcggggcatgtgaccaggatgtggatgagtgctccattggtgccaac
ccatgtgagcacctgggccggtgcgtgaacacacagggctcgttcctgtgccagtgcggc
cgtggctacactggcccgcgctgcgagaccgacgtcaacgagtgcctatccgggccctgc
cgcaaccaggccacgtgcctcgaccgcataggccagttcacctgcatctgcatggcaggc
tttacaggcacctattgtgaggtggacatggatgagtgtcaaagcagcccgtgtgtcaat
ggtggggtctgcaaggacagagtcaacggcttcagctgcacctgcccctcaggcttcagt
ggggccatgtgtcagctggatgtggatgagtgcgcaagcacaccctgccggaatggagcc
aagtgcgtggaccagcccgatggctacgaatgccgctgtgcagagggcttcgagggcacg
ctgtgtgagcgcaacgtggacgactgctccccggacccgtgccaccatgggcgctgtgtg
gacggcattgccagcttctcgtgcgcctgcgccccgggatacacaggcacgcgctgtgag
agccaggtggacgagtgccgcagccagccctgccgccacgggggcaaatgtctagacttg
gtggacaaatatctctgccgctgccctcctggcaccacaggagtgaactgcgaggtgaac
attgatgactgtgccagcaacccctgcacctttggagtctgccgggatggcatcaaccgc
tatgactgtgtctgccagcctggcttcacagggcccctttgcaacgtggagatcaacgag
tgtgcgtccagtccgtgcggtgatggaggttcctgtatggatggggaaaatggcttccac
tgcctctgccctcccggctccctgcccccactctgcctccccccgagccatccctgtgcc
caagaaccttgcagtcatggtgtctgccacgatgcacccggagggttccgctgtgtgtgt
gagcctggctggagtggtccccgatgcagccagagccttgctcgagatgcctgtgaatcg
cagccctgccagtccggcggcacctgcaccagcgatggaatgggcttccactgtacctgt
ccccctggtgtccagggccgtcagtgtgagctgccatccccctgtgccccgaacccctgt
gagcacgggggccactgtgagtctgccccgggccagctgcctgtctgctcctgccccccc
ggctggcaaggcccacgatgccagcaggatgtggatgaatgtgctggcccctcaccctgt
ggctcccacggtacctgcaccaacctggaggggagtttcagctgtacctgccataggggg
tatagtggcccttcctgtgatcaggacatcgatgactgtgaccccaacccctgcctgaat
ggtggctcctgtcaggatggcgtgggctccttttcgtgctcctgcctccctggcttcgct
ggtccccgttgtgcccgagatgtggacgagtgtctcagcagcccctgtggcccgggcacc
tgcaccgaccacgtggcctcctttacctgcacgtgcccacctggttatggaggtttccac
tgtgagcaggacctaccggactgcagccccagctcctgcttccatggcgggacctgcgtg
gacggcgtgagctcgttcagatgccagtgccgccccggctacactggcgcacactgccag
cacgaggccgacccctgcctctctcggccctgtctgcacgggggcgtctgcactgctgcc
caccctggcttccgctgcacctgcccggagggcttcactggcacgcagtgccagacgctg
gtagactggtgcagccgcgcgccctgtcagaacgggggtcgctgcgccccgaccggggcc
accttctactgcctttgccctccggggtggagcggccgcctctgtgacatccggagtgtg
ccctgcagggaggccgcagcccagctcggggtacggctggaagagctgtgtcagacaggt
gggcggtgtgtggataaggacaattcccactactgcgtgtgcccagaaggccgcacgggc
agccactgtgagcaggaggtggacccctgcttggcccagccctgccaacatgggggcacc
tgccgaggctacgtggggggttatgtgtgtgagtgtccagctggctacacgggggacaac
tgtgaggatgatgtagacgagtgtgcctcccagccctgccagcacggtggcttctgcatt
gaccttgtggcccgctatctctgctcctgccccccaggaacactgggcgtgctctgtgag
attaatgaggacgactgtggcccaggcccacccctggaccagggcccccggtgcctgcac
aatggtacctgtgtggacctggtgggtggcttccgctgcacctgcccccccgggtacact
ggcttgcgctgtgaggcggacatcaatgagtgtcacccgggtgcctgccatgatgcacac
actcgggattgtctgcaggacctaggtgggggcttccgctgcatttgccgagcaggcttc
acaggtccccgctgtcagactgtcctgtctccctgcgagtcccagccgtgccagcacgga
ggccagtgccgtcccagcccaggccctgggggtgtgctgacatttacctgtcactgcatt
ccgccgttctggggcccgcgttgcgagcgggtggcgcgctcctgccgggagctgcagtgt
ccggcgggcgtcccgtgccagcagacggtccgtgggccgcgctgcgcctgtccccccggg
ctgtcggggcccgcctgccgggcctgcgaggccaagagcggggacaagcgctgtgaccgc
gagtgcaacagcccgggctgcggctgggacggcggcgactgctcgctgagcgtgggcgac
ccctggcggcagtgcgcggcgctgcagtgctggcgcctcttcaacaacagtcgctgtgac
cccgcctgcagctcgcccgcctgcctctatgacaacttcgattgccgcgcgggcggccgc
gagcgcgcctgcaacccagtgtacgagaagtactgtgcggaccactttgccgatggccgc
tgcgaccagggctgcaacacggaggagtgcggctgggacgggctggactgtgcgggcgag
gtgccggccctgctggcccgcggcgtgctggtgctcaccgtgctgctgccgcccgaggag
ctgctgcgctccagcgccgacttcctgcagcggctcagcggcatcctgcgcacctcgctg
cgcttccgcctggacgaacacggccaggccatggtcttcccttaccaccggcccggtcct
ggctccgaatcccggaaccggcgggagctggcccctgaggtgatcggctctgtggtgatg
ctggagattgacaaccggctgtgcctgcagtcgcccgagaatgaccactgcttccccgat
gcgcagagcgcggccgactacctgggagcgctgtcggccgtggagcgccttgacttcccg
tacccgctgcgcgccgtgcggggggagcccctggagctgccagagccaagcgtgcccttg
cttcccctgctggccgccagcgccgtcttcctgctggtcatcctcgtcctgggtgtcatg
gtggcccggcgcaagcgcgagcacagcaccctctggttccccgagggcttcgcgctccac
aaggatgtggctgccggccacaagggccggcgggagcccgtgggccaagacgcgctgggc
atgaagaacatggccaagagcgagagtctgatgggggaggtggccacagactggatggac
acagagtgcccagaggctaagcgactgaaggtagaggagccctgtgtgggggctgaggat
gccgtggattgccgccagtggacccaacaccacctggttgccgcagacatccgtgtggca
ccagccatggcgctgacacccccgcagggcgatgtggatgctgatggcatggatgtcaat
gtgcgaggcccagatggcttcactccactgatgctggcctccttctgtgggggggccctg
gagccaatgcccactgaggaggatgaggcagaagacacatcagccagcatcatctcagac
ttgatctgccagggagcccagcttggggcacggactgaccgcacaggcgagacagccctg
cacctggctgcccgctacgcccgggctgatgcagccaagcggttgctggatgctggggca
gacaccaatgcccaggaccactcagggcgcactcctttgcacactgcagtcaccgcggat
gcccagggcgtgttccagattctcatccggaaccgctccacagacctggatgcccgcatg
gcggatggctctacggcactaattctggccgcccgcctggcggtggagggcatggtggaa
gagctcattgccagccatgctgatgtcaatgctgtggatgagcttgggaaatcagcctta
cactgggcagcagccgtcaacaatgtggaggccaccttggccctgctcaaaaatggagcc
aacaaggacatgcaggatagcaaggaggaaactccactgtttctggccgcccgtgagggc
agctatgaggctgccaagctgctgctggaccactttgccaaccgtgagatcacagaccac
ctggacaggctgccgcgggatgtggcccaggagcggctacaccaggacatcgtgcgtctg
ctggaccagcccagtgggccccgcagccctcacggtcctcatggcctggggcccctcctc
tgtccacccggggccttcctccctggcctcaaggtggcacagtcggggggcaagaagagc
cggaggccaccggggaagacgggtctggggccacagggcacccgggggcggggtaagaag
ctgacactggcctgcccgggtcccctggctgagagctcagtcacgctgtcgcccgtggac
tcgctggactccccgcggcccttcggtgggccccctgcgtcccctggtggcttctccctc
gaggggccctatgcagcagccaccgccacggccgtgtccctggctcagattggtggcgcg
ggccgggcgggtttagggcgccagccccctgggggctgcgtgctcagcttgggtttgctg
aaccccgtggccgttcccctcgactgggcccggctgcctccacctgccccgccaggcccc
tcattcctgctgccgctggcgccgggaccccagctgctgaaccccgggacccccgtgtcc
ccccaggagcggcccccgccatatctggcagccccgggacacgccgaggagtacccggca
gccggcgcccatggcagcccccccaaggcccgcttcctgagggttccgagcgagcaccct
tacctgaccccatcccccgagtcccccgagcactgggccagcccctcacctccctccctc
tcggactggtcagactccacgcccagcccagccactgccaccgggcctacggccacagcc
gctggggcgttgcctgcccagccgctccccctttccgtcccaggccccctagctcaggcc
cagacccagctggggccccaaccggaagtcacccccaagaggcaggtgttggcctga
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