Leptonychotes weddellii (Weddell seal): 102739921
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Entry
102739921 CDS
T08708
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
lww
Leptonychotes weddellii (Weddell seal)
Pathway
lww00020
Citrate cycle (TCA cycle)
lww00480
Glutathione metabolism
lww01100
Metabolic pathways
lww01200
Carbon metabolism
lww01210
2-Oxocarboxylic acid metabolism
lww01230
Biosynthesis of amino acids
lww04146
Peroxisome
lww05230
Central carbon metabolism in cancer
Module
lww_M00009
Citrate cycle (TCA cycle, Krebs cycle)
lww_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
lww00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
102739921 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
102739921 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
102739921 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
102739921 (IDH2)
Enzymes [BR:
lww01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
102739921 (IDH2)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
102739921
NCBI-ProteinID:
XP_006745417
UniProt:
A0A2U3YNW5
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All DBs
Position
Unknown
AA seq
452 aa
AA seq
DB search
MAGYLRVARSLCRVSSSGGPAWAPAAPTGPNLQEQPRRHYADKRIKVAKPVVEMDGDEMT
RIIWQFIKEKLILPHVAVQLKYFDLGLPRRDQTNDQVTIDSALATQKHGVAVKCATITPD
EARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQY
KATDFVVDRAGTFKIVFSPKDGSGAKEWEVFNFPAGGVGMGMYNTDESISGFAHSCFQYA
IQKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTDFDKNKIWYEHRLIDDMVAQVLK
SSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQ
KGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVQTVESGAMTKDLAGCI
HGLSNVKLNEHFLNTSDFLDTIKNNLDKALGQ
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atggctggctacctgcgggtcgcacgctcgctctgcagagtctccagctccggcgggccg
gcctgggcgccggcagccccgacgggccccaacttgcaggagcagccgcggcgccactat
gccgacaagaggatcaaggtggcgaagccggtggtggagatggacggcgatgagatgacc
cggatcatctggcagttcatcaaggagaagctcatcctaccccacgtggccgtccagctc
aagtacttcgacctggggctcccacgccgtgaccagaccaatgaccaggtcaccatagac
tctgcgttggccacccagaagcacggtgtggctgtcaagtgtgccaccatcacccctgat
gaggcccgtgtggaagagttcaagctgaagaagatgtggaagagtcccaacgggaccatc
cgaaacatcctcggggggaccgtcttccgggaacccatcatctgcaaaaacatcccccgc
ctcgtccctggctggaccaagcccatcaccattggcaggcacgcccacggcgaccagtac
aaggccacggactttgtggtggaccgggccggcacgttcaagatcgtcttctccccgaag
gacggcagtggcgcgaaggagtgggaggtgttcaacttccccgccggcggcgtggggatg
ggcatgtacaatacggacgagtccatctcgggttttgcacacagctgcttccagtatgcc
atccagaagaagtggccgctgtacatgagcaccaagaacaccatcctgaaagcctacgac
gggcgcttcaaggacatcttccaggagatctttgagaagcactataagaccgactttgac
aagaataagatctggtatgagcaccggcttattgacgacatggtggctcaggtcctcaag
tcttccggcggcttcgtgtgggcctgcaagaactacgacggagatgtgcagtcggatatc
ctggcgcagggctttggctcccttggcctgatgacgtctgtgctggtctgcccggatggg
aagaccatcgaggctgaggctgctcatggaacggtcacccgccattatcgggagcaccag
aagggccggcccaccagcacgaaccccattgccagcatctttgcctggacacgtggcctg
gagcaccgggggaagctggacgggaaccaggacctcatcaggtttgcgcagaccctggag
aaagtgtgtgtccagactgtggagagcggagccatgaccaaggacctggcaggctgcatc
catggcctcagcaatgtgaagctgaacgagcacttcctgaacacgtcggacttcctggac
accatcaagaacaacctggacaaggccctgggccagtag
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