KEGG   Leptonychotes weddellii (Weddell seal): 102740136
Entry
102740136         CDS       T08708                                 
Name
(RefSeq) phospholipid-transporting ATPase ABCA1
  KO
K05641  ATP-binding cassette, subfamily A (ABC1), member 1
Organism
lww  Leptonychotes weddellii (Weddell seal)
Pathway
lww02010  ABC transporters
lww04148  Efferocytosis
lww04975  Fat digestion and absorption
lww04979  Cholesterol metabolism
lww05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:lww00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    102740136
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    102740136
 09150 Organismal Systems
  09154 Digestive system
   04975 Fat digestion and absorption
    102740136
   04979 Cholesterol metabolism
    102740136
 09160 Human Diseases
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102740136
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:lww02000]
    102740136
Transporters [BR:lww02000]
 ABC transporters, eukaryotic type
  ABCA (ABC1) subfamily
   ABCA1, 2, 3, 4, 7, 12, 13 subgroups
    102740136
SSDB
Motif
Pfam: ABC_tran ABC2_membrane_3 R1_ABCA1 AAA_21 DUF4162 AAA_23
Other DBs
NCBI-GeneID: 102740136
NCBI-ProteinID: XP_030887199
UniProt: A0A7F8R1M5
LinkDB
Position
Unknown
AA seq 2146 aa
MPSAGTLPWVQGIICNANNPCFRYPTPGEAPGVLGNFNKSIVSRLFSDAQRLLLYSQKDT
SMKDIHQVLRTLQQIERSSPGKVLFLWNKELRSHVFWCMQHILEKAELSSWDKGGKKQSI
FFSFQRELNSTSPFLNKELVKATETLLDSLGTLAQELFSMNSWSDMRQEVMFLTNVNSSS
SSTQIYQAVSRIVCGHPEGGGLKIKSLNWYEDNNYKALFGGNGTDEDADSFYDNSTTPYC
NDLMKNLESSPLSRIIWKALKPLLVGKILYTPDTPVTRQVMAEVNKTFQELAVFHDVQGM
WEELSPKIWTFMESNPEMDLVRTLLDSRSNDHFWEQQLDGLDWTAKDILAFLAKHPEDVQ
SANGSVYTWREAFNETDQAIQTISRFMECVNLNKLEPVATEVRLISKSMELLDERKFWAG
IVFTGITPDSVELPRHVKYKIRMDIDNVERTNKIKDGYWDPGPRADPFEDMRYVWGGFAY
LQDVVEQAIIRVLTGTEKKTGVYVQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVI
IKGIVYEKEARLKETMRIMGLDNGILWFSWFISSLIPLLVSAGLLVVILKLGNLLPYSDP
SVVFVFLSMFAVVTILQCFLISTLFSRANLAAACGGIIYFILYLPYVLCVAWQDYVGFTL
KIFVSLLSPVAFGFGCEYFALFEEQGIGVQWDNLFESPVEEDGFNLTISVSMMLFDTFLY
GVMTWYIEAVFPGQYGIPRPWYFPCTKSYWFGEESDEKSHPGSSQKGASEICVEEEPTHL
KLGVSIQNLMKVYRDGMKVAVDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSG
TAYILGKDIRFEMSTIRQNLGVCPQHNVLFDMLTVEEHIWFYARLKGLSEKHVKAELEQM
ALDVGLPPSKLKSKTSQLSGGMKRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIWELL
LKYRQGRTIILSTHHMDEADILGDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDV
ESSLSSCRNSSSTVSYLKKEDSVSQSSSDAGLGSDHESDTLTIDVSAISNLIRKHVAEAR
LVEDIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGISETTLEEIFLKVAEES
GVDAETSDGTLPARRNRRAFGDKQSCLRPFTEDDATDPNDSDVDPESRETDLLSGMDGKG
SYQVKGWKLIQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYP
SLELQPWMYNEQYTFISNDAPEDMGTQELLNALTRHPGFGTRCMEGNPIPDMPCSVGEEE
WTTAPVPQTITDLFQNGNWTMENPSPTCQCSSDKIKKMLPVCPLGAGGLPPPQRKQNTAD
ILQNLTGRNISDYLVKTYVQIIAKSLKNKIWVNEFRYGGFSLGASNSHSLPSSQEVNNAI
KQVKKHLKLAKDSSADRFLSSLGRFMTGLDTKNNVKVWFNNKGWHAISSFLNVINNAILR
ASLQKGENPSQYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVF
LIQERVSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQKSYVSSTNL
PVLALLLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVLELFTNNK
LNNINDILKSVFLIFPHFCLGRGLIDMVKNQAMADALERFGENRFVSPLSWDLVGRNLFA
MAVEGVVFFLITVLIQYRFFIRPRPVDAKLPPLNDEDEDVKRERQRILDGGGQNDILEIK
ELTKIYRRKRKPAVDRICVGIPPGECFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNKN
SILSDIHEVHQNMGYCPQFDAITELLTGREHVEFFALLRGVPEKEVGKVGEWAIRKLGLV
KYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSIVKEGR
SVVLTSHSMEECEALCTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRIAGSNPDLKPV
QEFFGLAFPGSVLKEKHRNMLQYQLPSSLSSLARIFSILSQSKKRLHIEDYSVSQTTLDQ
VFVNFAKDQSDDDHLKDLSLHKNQTVVDVAVLTSFLQDEKVKESYV
NT seq 6441 nt   +upstreamnt  +downstreamnt
atgccctctgcaggaacgcttccttgggttcaggggattatctgtaatgccaataacccc
tgtttccgttatccgactcccggtgaggcccctggggttcttggaaactttaacaaatcc
atcgtgtctcgcctgttctcagatgctcagcggcttcttctgtatagccagaaagacacc
agcatgaaggacatacaccaagttctgaggacgttgcagcagatagagcgttccagtcca
gggaaagttctgtttctgtggaacaaagagctccgttcacatgtcttctggtgcatgcag
catattcttgaaaaggcagaactcagttcatgggacaaaggaggtaaaaaacaaagtatt
tttttctcattccagagggaactaaactctacatctcctttcctgaacaaggaactggtt
aaagccacagaaactttgctggatagtctcgggactttggcccaagagctgttcagcatg
aacagctggagcgacatgcggcaggaggtcatgttcctgaccaatgtgaacagctccagc
tcgtccacccagatataccaagccgtgtcccgcatcgtctgtggccatcccgagggcggg
ggcctgaagattaagtccctcaactggtacgaggacaacaactacaaagctctctttggt
ggcaacggcacggatgaagatgctgacagcttttatgacaattctacaactccttattgc
aatgatctgatgaagaatttggagtccagtcccctttcccgcatcatatggaaagctctc
aagcctctgcttgttgggaagatcctgtatacacctgacactccagtcacaaggcaggtt
atggccgaggtgaataagacctttcaggaactggctgtgtttcatgatgtgcaaggcatg
tgggaagagctcagccccaagatctggaccttcatggagagtaacccggaaatggacctt
gttcggacactgttggacagtagaagcaatgaccacttttgggaacagcagttggatggc
ttagactggactgccaaagatatcctggcatttctggccaagcacccagaggatgtccag
tctgctaacggctctgtgtacacctggagagaagctttcaatgagactgaccaggcaatc
cagaccatctctcgcttcatggagtgtgtcaacttgaataagctcgaaccggtagcaaca
gaagtccggctcatcagcaagtccatggagttgctggacgagcggaagttctgggccggt
atcgtgttcaccggaatcactcctgacagtgtggagttgccccgtcatgtcaagtacaag
atccgaatggacattgacaatgtggagaggacaaataaaatcaaggatgggtactgggac
cccggtcctcgggctgacccctttgaggatatgcggtatgtctgggggggctttgcctac
ttacaagatgtggtggaacaggcgatcatcagggtgctgacgggcaccgagaagaaaact
ggtgtctatgtgcagcagatgccctacccctgttatgtcgatgacatcttcctgcgggtg
atgagccggtccatgcccctgttcatgacgctggcctggatctactccgtggctgtgatc
atcaagggcatcgtgtatgagaaggaggcgcggctgaaggaaaccatgcgcatcatgggc
ctggacaacggcatcctgtggttcagctggttcatcagtagcctcattcctctgctcgtg
agcgccggcctgcttgtggtcatcctgaaattaggaaacctgctgccctacagtgacccc
agcgtggtgtttgtctttctgtccatgttcgccgtggtgaccatcctgcagtgtttcctg
atcagcacactcttctcaagagccaacctggcggcagcctgtgggggcatcatctacttc
attctctacctgccctacgtgctgtgcgtggcatggcaagactatgtgggcttcacgctc
aagatcttcgtgagcctgctgtctcctgtggctttcgggtttggctgtgagtactttgcc
ctttttgaggagcagggcattggggtgcagtgggacaacctgtttgagagccccgtggag
gaagatggcttcaacctcaccatttcagtctccatgatgctgttcgacaccttcctctat
ggagtgatgacgtggtacatcgaggctgtctttccaggccagtatggaatccccaggccc
tggtattttccttgcaccaaatcctactggttcggtgaggaaagtgatgaaaagagccac
cctggttccagccagaagggagcatcagaaatctgcgtggaggaggagcccacacacctg
aagctgggtgtgtccattcagaacctgatgaaggtttaccgggatggcatgaaggtggct
gttgatggcctggccttgaatttctatgagggccagatcacctccttcctgggccacaat
ggagctgggaagaccaccaccatgtcaatcctgaccgggttgttccctcccacctcgggc
actgcctacatcctgggaaaagacattcgctttgagatgagcaccatccggcagaacctg
ggggtctgcccccagcataacgtgctgtttgacatgctgactgtggaagaacacatctgg
ttctatgcgcggctgaaggggctctcggagaagcacgtgaaagcagagctggagcagatg
gccttggatgtcggtttgccacccagcaaactgaaaagcaaaacaagtcagctgtcaggc
ggaatgaagagaaagctgtctgtggctttggcctttgttgggggatccaaggttgtcatt
ctggacgagcccacagccggtgtggacccttactcccgcaggggaatatgggagctcctg
ctgaaataccgacaaggccgcaccattattctctccacgcaccacatggatgaagcagac
atcctgggggacaggattgccatcatttcccatgggaagctgtgctgtgtgggctcctcc
ctatttctgaagaaccagctgggaacaggctactacctgaccctggttaagaaggatgtg
gaatcctccctcagttcctgcagaaatagcagtagcactgtgtcgtacctgaagaaggag
gacagtgtttctcagagcagttctgatgctggcctgggcagcgaccatgaaagtgacacg
ctgaccatcgatgtctcggccatctccaacctcatcaggaagcacgtggctgaggcccgg
ctagtggaagacattgggcatgaactgacttacgtgctgccctacgaagctgccaaggag
ggggcctttgtggaactcttccatgagattgatgaccggctctcagacctgggcatctcc
agttacggcatctcggagacgaccctggaagaaatatttctcaaagtggccgaagagagt
ggggtggatgctgagacctcagatggcaccttgccagcaagacgaaacagacgggccttc
ggggacaagcagagctgccttcgcccattcactgaagatgatgctactgatcctaatgat
tctgatgtagacccagaatccagagaaacagacctgctcagtgggatggatggcaaaggc
tcctaccaggtgaagggctggaagctcatacagcagcagtttgtggcgcttctgtggaag
aggctgctgattgccagacggagtcggaagggattctttgctcagatcgtcctaccagct
gtgtttgtctgcattgccctggtgttcagcttgatcgtgcccccctttggcaagtacccc
agcctggaacttcagccctggatgtacaacgaacagtacacgttcatcagtaatgatgct
cctgaggacatgggcacccaggaactcttgaatgccctcaccagacaccccggcttcggg
acccgctgtatggaaggaaatccaatcccagacatgccctgctcggtgggggaggaggag
tggaccaccgcccccgttccccagaccatcacggacctcttccaaaatgggaactggacg
atggagaacccctcacctacctgccagtgtagcagtgacaaaatcaagaagatgctgccc
gtgtgtcccctgggggcaggggggctgcctcctccacaaagaaaacagaacactgcagac
atccttcagaacctgacgggaagaaacatttcggattatctggtgaagacctatgtgcag
atcatagccaaaagtttaaagaacaagatctgggtgaatgagtttaggtatggagggttt
tccctgggtgccagtaattctcattcacttccttcaagtcaagaagttaataatgccatc
aagcaagtgaagaagcacttgaagctggccaaggacagttctgcagatcgatttctcagc
agcttggggaggttcatgacaggactggacacgaaaaataacgtcaaggtgtggttcaac
aacaagggctggcatgccatcagctctttcctgaacgtcatcaacaatgccattctgcgg
gccagcctgcagaagggagagaaccccagccagtatgggattactgccttcaatcacccc
ctgaatctcaccaagcagcagctctcggaagtggctctgatgaccacgtcagtggatgtc
cttgtgtccatctgtgtcatcttcgcgatgtccttcgtcccggccagctttgttgtgttc
ctgatccaagagcgggtcagcaaagcgaagcacctgcagttcatcagtggagtaaagcct
gtcatctactggctttccaatttcgtgtgggatatgtgcaactatgtggtccctgccacg
ctggtcattatcatcttcatctgcttccagcagaagtcctatgtgtcctctaccaacctg
cctgtgctggcccttctacttctgttgtacgggtggtcgatcacacctctcatgtaccca
gcctccttcgtgttcaagatccccagcacagcctacgtggtcctcaccagcgtgaacctc
ttcatcgggatcaacggcagtgtggccacttttgtgctggagctttttaccaacaataag
ctgaataacatcaatgatatcctgaagtctgtattcttgatcttcccacatttttgcctg
ggacgggggctcattgacatggtgaaaaaccaggcaatggctgacgccttggaaaggttt
ggggagaaccgttttgtttcgccactgtcctgggacttagtgggacggaacctcttcgcc
atggccgtggaaggggtggtattcttcctcatcactgttctcatccagtacagattcttc
atcaggcccagacctgtagatgcaaagcttcctcctttgaatgatgaggatgaagatgtg
aagcgggaaagacagagaattcttgatggtggaggacagaacgacatcttggaaatcaag
gagctgactaagatatatagaagaaagaggaagcctgccgttgacaggatttgcgttggc
attccgcctggcgagtgctttggacttctgggagttaatggggctgggaaatcatcaact
ttcaagatgttaactggagataccactgttaccagaggagatgctttcctgaacaaaaat
agtatcttatcagacatccatgaagtccatcagaacatgggctattgccctcagttcgat
gccatcacagagctgttgaccggaagagagcatgtggagttctttgccctcttgagagga
gtcccagagaaagaagttggcaaggttggtgaatgggcaattcggaaactgggccttgta
aagtatggagaaaaatatgctggcaactacagtggaggcaacaagcgcaagctctcaacg
gccatggctctgatcggcgggccccctgtcgtgtttctggatgaacctaccacaggcatg
gaccccaaagcccggcgattcttgtggaattgtgccctaagtattgtcaaggaaggcaga
tcagtagtgcttacatctcatagtatggaagaatgtgaagctctttgcactaggatggca
attatggtcaatgggaggttcaggtgtctcggcagcgtccaacatctgaaaaataggttt
ggagatggttacacaatcgtggtacggatagcagggtccaaccctgacctgaagcctgtc
caggagttcttcggacttgccttcccgggaagtgtcctcaaagagaagcaccggaacatg
ctacagtaccagcttccatcttcactatcttctctggccaggatattcagcatcctttcc
cagagcaaaaagagactccacatagaagactactctgtttctcagacaacgcttgaccaa
gtatttgtaaacttcgccaaggaccaaagtgatgatgaccacttaaaggacttgtcatta
cacaaaaaccagacagtagtcgatgttgcagttctcacatcttttctccaggatgagaaa
gtgaaagaaagttacgtatga

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