Leptonychotes weddellii (Weddell seal): 102740893 Help Entry 102740893         CDS       T08708                                  Symbol TOP2B Name (RefSeq) DNA topoisomerase 2-beta   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism lww  Leptonychotes weddellii (Weddell seal) Pathway lww01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:lww00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     102740893 (TOP2B)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:lww03032]     102740893 (TOP2B)    03036 Chromosome and associated proteins [BR:lww03036]     102740893 (TOP2B) Enzymes [BR:lww01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      102740893 (TOP2B) DNA replication proteins [BR:lww03032]  Eukaryotic type   DNA Topoisomerases    102740893 (TOP2B) Chromosome and associated proteins [BR:lww03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     102740893 (TOP2B)   Centrosome formation proteins    Centriole proteins     102740893 (TOP2B) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT Toprim HATPase_c Microp_apicomplexa_20 Motif Other DBs NCBI-GeneID:  102740893 NCBI-ProteinID:  XP_030886643 UniProt:  A0A7F8R1W2 LinkDB All DBs Position Unknown AA seq 1580 aa AA seqDB search MIASSSKLMTLFDQNNAAKKEESETANKNDSSKKLSVERVYQKKTQLEHILLRPDTYIGS VEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDPES NIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIF STKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLSKFKMEKLDK DIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHELA NERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSVKP FQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESILN WVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVSGL GVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTLRY GKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYSIP EFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITLAF SKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDNER SIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNLAQ NFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLSRLLFPAVDDNLLKFLYDDN QRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDPHPMLPNYK NFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTPAL ISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKKYE TVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKKDL IQMLVQRGYESDPVKAWKEAQEKVIICRTRHSEKLLKANSKTDTVQEFAVHTHHKALCQC DSTRAWRNDSRCEKKVEAQEREDVLAGMAGKAIKGKVGKPKVKKLQLEETMPSPYGRRIV PEITAMKADVSKKLLKKKKGDLDTTTVKVEFDEEFSGTPVEGTGEEALVPSAPVNKGPKP KREKKEPGTRVRKTPTSSGKSSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRA AAERPKYTFDFSEEEDDDADDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFS PGKSKATPEKSSHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQT DKVPSKTVAAKKGKPSSDTTAKPKRAPKQKKVEPINSDSDSEFGIPKKTTPPKGKGRGAK KRKASGSENEGDYNPGRKTSKTTSKKPKKTSFDQDSDVDIFPSDFTSEPPSLPRTGRARK EVKYFAESDEEEDVDFAMFN NT seq 4743 nt NT seq  +upstreamnt  +downstreamnt atgattgcaagcagttctaagttaatgactctttttgatcagaacaatgctgcaaaaaaa gaagagtcagaaactgcaaacaaaaatgattcttcaaagaagttgtctgttgagagagtg tatcagaaaaagacacaacttgaacatattctccttcgtcctgatacatatattgggtca gtggaaccattgacacagctaatgtgggtgtatgatgaagatgtaggaatgaattgcaga gaggttacctttgtgccaggtttatacaagatctttgatgaaattttggttaatgcagct gacaataaacagagggataagaatatgacctgtattaaagtttctattgatcctgaatca aatattataagcatttggaataatgggaaaggcattccagtagtagaacacaaagtagag aaagtttatgttccagcgttaatttttggacagcttttaacatccagtaactatgatgat gatgagaaaaaagtaacaggtggtcgcaatggttatggtgcaaaactttgtaatattttc agtacaaagtttacagtagaaactgcttgcaaagaatacaaacatagttttaagcagaca tggatgaataacatgatgaagacttctgaagccaaaattaagcattttgatggtgaagat tacacatgcataacattccaaccagatctgtctaaatttaagatggaaaagcttgacaag gatattgtggccctcatgaccagaagagcttatgatttggctggttcatgcaagggggtc aaggtcatgtttaatggaaagaaattgcctgtaaatggatttcgcagttatgtagatctt tatgtgaaagacaagttggatgaaactggagtggcgctgaaagttattcatgaacttgca aatgaaagatgggatgtttgtctcacactgagtgaaaagggattccagcaaatcagcttt gtaaatagtattgcaacaacaaaaggtggacgtcatgtggattatgtagtagatcaagtt gttggtaaactgattgaagtagttaagaaaaagaacaaagctggtgtatcagtaaaacca tttcaagtaaagaaccatatatgggtttttattaattgccttattgaaaatccaactttt gattctcagactaaggaaaacatgactctgcaacccaaaagttttgggtccaaatgccaa ctgtcagaaaaattttttaaagcagcttctaactgtggcattgtagaaagtattctgaat tgggtgaaatttaaagcccagactcagctgaacaagaagtgttcatcagtaaagtatagt aaaatcaaaggtattcccaaactggatgatgctaatgatgctggtggcaaacattccctg gagtgtacactgatattaacagagggagactctgccaaatcgttggctgtgtctggatta ggtgtgattgggcgagacagatatggagtctttccacttaggggaaaaattcttaacgta cgggaagcttctcataaacagatcatggaaaatgcagaaataaacaatattatcaaaata gttggtctacagtacaagaaaagttatgatgatgcagaatctctgaaaactttacgctat gggaagattatgattatgactgatcaggatcaagatggttctcacattaaaggcctgctt attaatttcatccatcacaattggccatcacttttgaagcatggctttcttgaagagttc attactcctattgtgaaggctagcaaaaataagcaggaactttccttctatagtattcct gaatttgatgagtggaaaaaacatatagaaaaccagaaagcctggaaaataaaatactac aaagggttgggtaccagcacagctaaagaagcaaaggaatattttgctgatatggaaagg caccgcatcttgtttagatatgctggtcctgaagacgatgctgccattaccttggcattc agtaaaaagaagattgatgacagaaaagaatggttaaccaattttatggaagaccggaga cagcgtaggttacatggcttaccagagcaatttttgtatggtacagcaacaaaacatttg acttacaatgatttcatcaacaaggaattgattctcttctcaaactcagacaatgaaaga tctataccatctcttgttgatggttttaaaccaggacaacgaaaagttttatttacctgt ttcaagaggaatgataaacgtgaagtaaaagttgcccagttggctggatctgttgctgag atgtctgcttatcatcatggagaacaagcattgatgatgactattgtgaatttggctcag aactttgtgggaagcaacaacattaacttgcttcagcctattggtcagtttggaactcgg cttcatggtggcaaagatgctgcaagccctcgttatattttcacaatgttaagctcttta tcaagactgctttttcctgctgtggatgacaacctgctcaaattcctttatgatgataat caacgcgttgaacctgagtggtatattcctataattcccatggttttaataaatggtgct gagggcattggtactggatgggcttgtaaactacccaactatgatgctagggaaattgtg aacaatgtcagacgaatgctagatggcttggatcctcatcctatgcttccaaattacaaa aactttaaaggaaccatccaagagcttggtcaaaaccagtatgcagtcagtggtgaaata tttgtggtggatagaaacacagtggagattacagagcttccagttagaacttggacacag gtatacaaagaacaggttttagaacctatgttaaatggaacagataaaacaccggcatta atttctgattataaagaatatcatactgatacaactgtgaaatttgtggtgaaaatgact gaagagaagctagcacaagcagaagctgctggattgcacaaagtttttaaacttcaaact actcttacgtgtaattccatggtactctttgatcatatgggatgtctcaagaagtatgaa accgtgcaagacattttgaaagaattctttgatttacgattaagttattatggtttacgt aaggagtggcttgtaggaatgttgggagcagaatctacaaagcttaacaatcaagcccgt ttcattttagagaagatacaaggaaaaattactatagagaataggtcaaagaaagatttg attcaaatgttagtccagagaggttatgaatctgacccagtgaaagcctggaaagaagca caagaaaaggtaatcatttgcagaacaagacattcagagaagcttttaaaagcaaattcc aaaacagatacagtacaggaatttgcagtgcacacccaccacaaagcactttgccagtgt gactcaaccagggcctggagaaatgactccaggtgtgagaagaaagtggaagcacaagaa cgagaggatgttctggccggaatggctggaaaagcaataaaaggtaaagttggcaaacct aaggtgaagaaacttcaattggaagagacaatgccctcaccttatgggagaagaatagtt cctgaaattactgctatgaaggcagatgtcagcaaaaagttgctgaagaagaaaaagggt gatcttgataccacaacagtaaaagtagaatttgatgaagaatttagtggaacaccagta gagggtactggagaagaggcattggtcccgtcagctcctgtaaataaaggtcccaaaccc aaaagggagaaaaaggagcctggtaccagggtgagaaaaacacctacatcatctggtaaa tccagtgcaaagaaagtgaagaaacggaatccttggtcagatgatgaatccaagtcagaa agtgacttggaagaaacagaacctgtggttattccaagagattctttgcttaggagagca gctgctgaaaggcctaagtacacatttgatttctcagaagaagaggatgatgatgctgat gatgatgacgacaataatgatttagaggagctgaaagttaaagcatctcccataacaaat gatggggaagatgaatttgttccttcagatggcctagataaagatgaatatacattttca ccaggcaaatcaaaagctactccagaaaaatcttcacatgacaaaaaaagtcaagatttt gggaatctcttctcatttccttcatactctcagaagtcagaagatgattcagctaaattt gacagtaatgaagaagattctgcctctgttttttcaccatcatttggtctgaaacaaaca gataaggttccaagtaaaacagtagctgctaaaaagggaaaaccgtcttcagatacaact gctaagcccaagagagctcctaaacagaagaaagtagagcctatcaactctgactcagat tcagaatttggcattccaaagaagactacacccccaaaaggtaaaggccgaggggcaaag aaaaggaaagcatctggctctgaaaatgaaggtgattataaccctggcaggaaaacatcc aaaacaacaagcaagaaaccgaagaaaacatcttttgatcaggattcagatgtggacatc ttcccatcagacttcacttctgaaccaccttctctgccacggaccggtagggctaggaaa gaagtaaaatattttgcagagtctgatgaagaagaagatgttgattttgcaatgtttaat taa

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