Leptonychotes weddellii (Weddell seal): 102741598 Help Entry 102741598         CDS       T08708                                  Symbol ADCY3 Name (RefSeq) adenylate cyclase type 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism lww  Leptonychotes weddellii (Weddell seal) Pathway lww00230   Purine metabolism lww01100   Metabolic pathways lww01522   Endocrine resistance lww04015   Rap1 signaling pathway lww04020   Calcium signaling pathway lww04022   cGMP-PKG signaling pathway lww04024   cAMP signaling pathway lww04062   Chemokine signaling pathway lww04072   Phospholipase D signaling pathway lww04081   Hormone signaling lww04082   Neuroactive ligand signaling lww04114   Oocyte meiosis lww04211   Longevity regulating pathway lww04213   Longevity regulating pathway - multiple species lww04261   Adrenergic signaling in cardiomyocytes lww04270   Vascular smooth muscle contraction lww04371   Apelin signaling pathway lww04540   Gap junction lww04611   Platelet activation lww04713   Circadian entrainment lww04714   Thermogenesis lww04723   Retrograde endocannabinoid signaling lww04724   Glutamatergic synapse lww04725   Cholinergic synapse lww04727   GABAergic synapse lww04740   Olfactory transduction lww04750   Inflammatory mediator regulation of TRP channels lww04911   Insulin secretion lww04912   GnRH signaling pathway lww04913   Ovarian steroidogenesis lww04914   Progesterone-mediated oocyte maturation lww04915   Estrogen signaling pathway lww04916   Melanogenesis lww04918   Thyroid hormone synthesis lww04921   Oxytocin signaling pathway lww04923   Regulation of lipolysis in adipocytes lww04925   Aldosterone synthesis and secretion lww04926   Relaxin signaling pathway lww04927   Cortisol synthesis and secretion lww04928   Parathyroid hormone synthesis, secretion and action lww04934   Cushing syndrome lww04935   Growth hormone synthesis, secretion and action lww04962   Vasopressin-regulated water reabsorption lww04970   Salivary secretion lww04971   Gastric acid secretion lww04972   Pancreatic secretion lww04976   Bile secretion lww05032   Morphine addiction lww05163   Human cytomegalovirus infection lww05166   Human T-cell leukemia virus 1 infection lww05200   Pathways in cancer lww05207   Chemical carcinogenesis - receptor activation lww05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lww00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102741598 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102741598 (ADCY3)    04371 Apelin signaling pathway     102741598 (ADCY3)    04020 Calcium signaling pathway     102741598 (ADCY3)    04072 Phospholipase D signaling pathway     102741598 (ADCY3)    04024 cAMP signaling pathway     102741598 (ADCY3)    04022 cGMP-PKG signaling pathway     102741598 (ADCY3)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102741598 (ADCY3)    04081 Hormone signaling     102741598 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102741598 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     102741598 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102741598 (ADCY3)    04062 Chemokine signaling pathway     102741598 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     102741598 (ADCY3)    04923 Regulation of lipolysis in adipocytes     102741598 (ADCY3)    04912 GnRH signaling pathway     102741598 (ADCY3)    04913 Ovarian steroidogenesis     102741598 (ADCY3)    04915 Estrogen signaling pathway     102741598 (ADCY3)    04914 Progesterone-mediated oocyte maturation     102741598 (ADCY3)    04921 Oxytocin signaling pathway     102741598 (ADCY3)    04926 Relaxin signaling pathway     102741598 (ADCY3)    04935 Growth hormone synthesis, secretion and action     102741598 (ADCY3)    04918 Thyroid hormone synthesis     102741598 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     102741598 (ADCY3)    04916 Melanogenesis     102741598 (ADCY3)    04925 Aldosterone synthesis and secretion     102741598 (ADCY3)    04927 Cortisol synthesis and secretion     102741598 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102741598 (ADCY3)    04270 Vascular smooth muscle contraction     102741598 (ADCY3)   09154 Digestive system    04970 Salivary secretion     102741598 (ADCY3)    04971 Gastric acid secretion     102741598 (ADCY3)    04972 Pancreatic secretion     102741598 (ADCY3)    04976 Bile secretion     102741598 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     102741598 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     102741598 (ADCY3)    04727 GABAergic synapse     102741598 (ADCY3)    04725 Cholinergic synapse     102741598 (ADCY3)    04723 Retrograde endocannabinoid signaling     102741598 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     102741598 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     102741598 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     102741598 (ADCY3)    04213 Longevity regulating pathway - multiple species     102741598 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     102741598 (ADCY3)    04714 Thermogenesis     102741598 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102741598 (ADCY3)    05207 Chemical carcinogenesis - receptor activation     102741598 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102741598 (ADCY3)    05163 Human cytomegalovirus infection     102741598 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     102741598 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102741598 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102741598 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102741598 (ADCY3) Enzymes [BR:lww01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102741598 (ADCY3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Motif Other DBs NCBI-GeneID:  102741598 NCBI-ProteinID:  XP_030892614 UniProt:  A0A7F8RHM3 LinkDB All DBs Position Unknown AA seq 648 aa AA seqDB search MDSTGNVHLLGHHGALRNGVPASSKPSSPALIETKEPNGSIHTSGSTSGEPDEQDGQADN PSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESAQVVKKRNTFLLSMRFMD PEMETRYSVEKEKQSGAAFSCSCVVLLCTALVEILIDPWLTTNYVTFVVGEVLLLILTIC SLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMANVVDMLSCLQYYAGPNNS TAGLEAEDGCVENPKYYNYVAVLSLIATIMLVQVSHMVKLTLMLLVTGAVAVINIYAWRP IFDEYDRRRFQEHDFPVVALEKMQGFSTPGLNGTGRLPLVPSKYSMTMMIFVMMLSFYYF SRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEHVARHFLGSKKRDEELYS QSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDFDSLLDNPKFRVITKIKT IGSTYMAASGVTPDVNTNGFASSNKEEKSDKERWQHLADLADFALAMKDTLTNINNQSFN NFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMGNIQVVEETQAILREY GFRFVRRGPIFVKGKGELLTFFLKGREKPAAFPNGSSVTLPHQVVDNS NT seq 1947 nt NT seq  +upstreamnt  +downstreamnt atggattccacaggcaacgttcacctgctcggccaccacggggccctgcgaaacggagtg ccagcttcctccaagcccagctcccccgccctcattgagaccaaggagcccaatgggagc atccacaccagcggctccacatcgggggagcctgacgagcaggatggccaggctgacaat ccctcgttccccaacccacgccggaggctgcgccttcaggacctggctgaccgagtggtg gacgcctctgaggacgagcatgagctcaaccagctactcaacgaggccctgcttgagcga gagtccgcccaggtagtgaagaagagaaacaccttcctcctttccatgcggttcatggac cccgagatggaaacccgctactcagtggagaaggaaaagcagagcggggctgccttcagc tgctcctgcgttgtcctgctctgcacggcgctggtcgagatactcatcgacccctggctg acgacgaactacgtgacctttgtggtcggggaggttctgcttctgatcctgacaatctgc tcgctggccgccatctttccccgggcctttcctaagaagctcgttgccttctcgacttgg atcgaccggacccgctgggccaggaacacctgggccatgttagccatcttcattctggtt atggcaaacgtcgtggacatgctcagctgtctccagtactacgcaggaccgaacaacagc accgcagggctggaggcggaggatggctgcgtagagaaccccaagtattacaactacgtc gccgtgctgtccctcattgccaccatcatgctggtgcaggtcagccacatggtgaagctc acactcatgctgctcgtcaccggggctgtggccgtcatcaacatctatgcctggcgcccc atctttgatgaatacgaccgcagacgttttcaggaacatgactttcccgtggtcgcctta gagaagatgcagggattttccacccctgggctcaacggcactggcaggctgcccctggtg ccttctaagtactccatgaccatgatgatctttgtcatgatgctgagcttctactacttc tcacgccacgtggaaaaactggcaaggacactgttcttgtggaagatcgaggtccacgac cagaaggaacgtgtctacgagatgcggcgctggaatgaggccttggtcactaacatgttg cctgagcacgtggcacgccatttcctggggtccaagaagagagatgaggagctgtacagc cagtcttacgatgagattggagtcatgtttgcctccctgcccaacttcgccgacttctac acggaggagagcatcaataatggtggcattgagtgtctgcgcttcctcaatgagatcatc tcagattttgattctctcctggacaatcccaaattccgggtcatcaccaagatcaaaacc attggcagtacctatatggcagcttcaggagtcaccccagatgtcaacaccaacggcttt gccagctccaacaaggaggagaagtcagacaaggagcgctggcagcacctggccgatctg gccgactttgccctggccatgaaggatacgctcacaaacatcaacaaccagtccttcaac aacttcatgctgcgcatcggcatgaacaaaggaggggtcctggctggggtcattggagcc cggaaaccacactatgacatctggggcaatacggtcaatgtggccagcaggatggagtcc acaggggtcatgggcaacattcaggtggtggaagaaacacaagccatcctccgagagtac ggcttccgctttgtgaggcgagggcccatctttgtgaaagggaagggggaactgctaacc tttttcctgaaggggcgtgagaagccagctgccttccctaacggctcctcggtcaccctg ccccaccaggtggtggacaactcctga

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