KEGG   Leptonychotes weddellii (Weddell seal): 102743800
Entry
102743800         CDS       T08708                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X2
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
lww  Leptonychotes weddellii (Weddell seal)
Pathway
lww04010  MAPK signaling pathway
lww04015  Rap1 signaling pathway
lww04218  Cellular senescence
lww04380  Osteoclast differentiation
lww04620  Toll-like receptor signaling pathway
lww04664  Fc epsilon RI signaling pathway
lww04668  TNF signaling pathway
lww04750  Inflammatory mediator regulation of TRP channels
lww04912  GnRH signaling pathway
lww04935  Growth hormone synthesis, secretion and action
lww04936  Alcoholic liver disease
lww05014  Amyotrophic lateral sclerosis
lww05022  Pathways of neurodegeneration - multiple diseases
lww05132  Salmonella infection
lww05135  Yersinia infection
lww05145  Toxoplasmosis
lww05161  Hepatitis B
lww05163  Human cytomegalovirus infection
lww05167  Kaposi sarcoma-associated herpesvirus infection
lww05169  Epstein-Barr virus infection
lww05170  Human immunodeficiency virus 1 infection
lww05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
lww05417  Lipid and atherosclerosis
lww05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:lww00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102743800 (MAP2K6)
   04015 Rap1 signaling pathway
    102743800 (MAP2K6)
   04668 TNF signaling pathway
    102743800 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    102743800 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    102743800 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    102743800 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    102743800 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    102743800 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102743800 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102743800 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102743800 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102743800 (MAP2K6)
   05161 Hepatitis B
    102743800 (MAP2K6)
   05163 Human cytomegalovirus infection
    102743800 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102743800 (MAP2K6)
   05169 Epstein-Barr virus infection
    102743800 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102743800 (MAP2K6)
   05135 Yersinia infection
    102743800 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102743800 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    102743800 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    102743800 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102743800 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    102743800 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102743800 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lww01001]
    102743800 (MAP2K6)
Enzymes [BR:lww01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     102743800 (MAP2K6)
Protein kinases [BR:lww01001]
 Serine/threonine kinases: STE group
  STE7 family
   102743800 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Choline_kinase Haspin_kinase CLP1_P DUF4344 APH
Other DBs
NCBI-GeneID: 102743800
NCBI-ProteinID: XP_006732123
UniProt: A0A2U3XLA8
LinkDB
Position
Unknown
AA seq 334 aa
MSQSKGRKRNPGLKIPKEAFEQPQPSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaggaagcgaaaccctggccttaaaattccaaaagaagcattt
gaacaacctcagcccagttccacgccacctcgagacttagactctaaagcttgcatttct
attggaaatcagaactttgaggtgaaggcggatgacctggagcctataatggaactgggg
cgaggtgcgtacggggtggtggagaagatgcgacacgtgcccagcgggcagatcatggcg
gtgaagcggatccgggccacagtaaatagccaggagcagaaaaggctactgatggatttg
gatatttccatgaggacagtggactgtccttttaccgtcaccttttatggtgcactcttc
cgggagggtgatgtttggatctgcatggagctcatggatacgtcgctagataaattctac
aaacaagtgatcgataaaggccaaacaattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagcgttagaacacttacacagtaagctctctgtcattcatcgagacgtc
aagccttccaacgtgctgatcaacactctgggccaagtaaagatgtgcgattttggaatc
agtggctaccttgtagactctgttgctaaaactattgatgcaggatgcaaaccgtacatg
gcccctgaaagaataaacccagagctcaatcagaagggatacagtgtgaagtctgacatt
tggagtctgggcatcacaatgattgagttggcgatccttcggtttccctacgactcttgg
ggaacccccttccagcagctcaaacaggtggtcgaggaaccctcgccacaactcccggcg
gataaattctccgaagagtttgttgactttacctcacagtgcttgaagaagaattccaaa
gaacggccaacatatccagaacttatgcaacatccatttttcaccctacacgaatccaaa
gcaacagacgtggcatcttttgtaaaactgattcttggagactaa

DBGET integrated database retrieval system