KEGG   Leptonychotes weddellii (Weddell seal): 102745264
Entry
102745264         CDS       T08708                                 
Symbol
NDUFS1
Name
(RefSeq) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
  KO
K03934  NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
Organism
lww  Leptonychotes weddellii (Weddell seal)
Pathway
lww00190  Oxidative phosphorylation
lww01100  Metabolic pathways
lww04714  Thermogenesis
lww04723  Retrograde endocannabinoid signaling
lww04932  Non-alcoholic fatty liver disease
lww05010  Alzheimer disease
lww05012  Parkinson disease
lww05014  Amyotrophic lateral sclerosis
lww05016  Huntington disease
lww05020  Prion disease
lww05022  Pathways of neurodegeneration - multiple diseases
lww05208  Chemical carcinogenesis - reactive oxygen species
lww05415  Diabetic cardiomyopathy
Module
lww_M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:lww00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    102745264 (NDUFS1)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    102745264 (NDUFS1)
  09159 Environmental adaptation
   04714 Thermogenesis
    102745264 (NDUFS1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    102745264 (NDUFS1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102745264 (NDUFS1)
   05012 Parkinson disease
    102745264 (NDUFS1)
   05014 Amyotrophic lateral sclerosis
    102745264 (NDUFS1)
   05016 Huntington disease
    102745264 (NDUFS1)
   05020 Prion disease
    102745264 (NDUFS1)
   05022 Pathways of neurodegeneration - multiple diseases
    102745264 (NDUFS1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    102745264 (NDUFS1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    102745264 (NDUFS1)
Enzymes [BR:lww01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     102745264 (NDUFS1)
SSDB
Motif
Pfam: Molybdopterin Fer4_Nqo3 Fer4_NDSU1 NADH-G_4Fe-4S_3 NADH_dhqG_C Fer2_4 ACR_tran Fer2
Other DBs
NCBI-GeneID: 102745264
NCBI-ProteinID: XP_030888983
UniProt: A0A7F8R8I3
LinkDB
Position
Unknown
AA seq 629 aa
MQIPRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVM
EFLLANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCI
QCTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNVIDICPVGALTSKPYA
FTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGL
KRQRLTEPMVRNEKGLLTYTSWEDALSRVAGMLQSFQGNDVAAIAGGLVDAEALIALKDL
LNRVDSDTLCTEEVFPTTGAGTDLRSSYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNAR
IRKSWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIAFGSHPFSQVLHEAKKPMVVVG
SSALQRSDGAAILEAISNIAQKIQMSSGVTGDWKVMNILHRYVGCPFHLFAGHHGDVGAP
IADVILPGAAYTEKSATYVNTEGRAQQTKVAVTPPGLAREDWKILRALSEIAGMTLPYDT
LDQVRNRLEEVSPNLVRYDDVEGANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYMTD
SISRASQTMAKCVKAVTEGAQAVEEPSIC
NT seq 1890 nt   +upstreamnt  +downstreamnt
atgcagatccctcgattctgttatcatgaaagattgtctgttgctggaaactgcaggatg
tgcctggttgaaattgagaaagctcctaaggttgtagctgcttgtgccatgccagtaatg
aaaggttggaatatcctgacaaactcagagaaatctaagaaagccagagaaggtgtgatg
gagttcttgttagcaaatcacccactggactgtcctatttgtgaccagggaggtgaatgt
gatctgcaggaccagtccatgatgttcggaagtgataggagccgatttttagaggggaaa
cgtgctgtggaggacaagaatattgggccattggtaaagaccatcatgactagatgtata
caatgtactcgctgcatcaggtttgcaagtgagattgcaggagtagatgatttgggaaca
acaggcagaggaaatgatatgcaagttggcacgtacattgaaaagatgttcatgtctgaa
ctgtctggaaatgtcattgatatctgccctgtaggtgccctgacctctaagccctatgct
tttactgcccgcccttgggaaacaagaaagacagaatccattgatgtcatggatgcggtt
ggaagtaatattgtggtaagcacaagaacaggagaggtgatgaggattttaccaaggatg
catgaggacatcaatgaagagtggatctctgataaaaccagatttgcctatgatgggcta
aaacgtcaaagacttaccgagccgatggtcagaaatgaaaaggggcttttaacctatacc
tcctgggaggatgcactctctcgtgtagctggaatgttgcagagttttcaaggcaatgat
gtggcagcaattgcaggtggcttggtggatgccgaagccctaatagctctcaaagatttg
cttaatagagtggactctgacaccttgtgcacggaagaggtcttccccactacaggagct
ggcacagatttgcgttccagttatcttcttaatactacaattgctggtgtggaagaggca
gatgttgtccttctggttggtacaaatccacgttttgaggcaccactatttaatgctaga
attcgaaagagctggcttcacaatgacttaaaagtggcccttattggcagcccagtggat
ctcacttatagatatgaccatctgggagattctcccaaaattcttcaagacattgctttc
ggtagccatccattcagccaggtattacatgaagctaaaaaaccaatggtggttgtaggc
agttctgcactccagagaagtgatggggcagcaattcttgaagctatttccaacattgct
caaaagattcagatgagtagtggtgttactggtgattggaaagttatgaatatccttcat
aggtatgttggttgtcctttccatcttttcgcaggacatcatggtgacgttggcgctcct
atagctgatgttattctcccaggcgctgcttacacagagaaatctgctacttatgtcaat
actgagggccgagctcagcagactaaagtagcagtgacacctcctggcttggcaagagaa
gactggaaaattctaagagccctctctgagattgcaggtatgactcttccatatgatact
ctggatcaagtaaggaacagattggaagaagtctctcctaatcttgtccgatatgatgat
gtcgaaggagccaattatttccagcaagcaaatgagctctctaagctagtgaaccaacag
cttcttgctgatccacttgttccacctcagctaacaataaaagacttctacatgacagac
tcaattagcagagcttcacagacaatggccaaatgtgtaaaagctgtcacggagggtgcc
caggcagtagaggaaccatccatatgctga

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