Leptonychotes weddellii (Weddell seal): 102745822
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Entry
102745822 CDS
T08708
Symbol
SOS1
Name
(RefSeq) LOW QUALITY PROTEIN: son of sevenless homolog 1
KO
K03099
son of sevenless
Organism
lww
Leptonychotes weddellii (Weddell seal)
Pathway
lww01521
EGFR tyrosine kinase inhibitor resistance
lww01522
Endocrine resistance
lww04010
MAPK signaling pathway
lww04012
ErbB signaling pathway
lww04014
Ras signaling pathway
lww04062
Chemokine signaling pathway
lww04068
FoxO signaling pathway
lww04072
Phospholipase D signaling pathway
lww04150
mTOR signaling pathway
lww04151
PI3K-Akt signaling pathway
lww04510
Focal adhesion
lww04540
Gap junction
lww04630
JAK-STAT signaling pathway
lww04650
Natural killer cell mediated cytotoxicity
lww04660
T cell receptor signaling pathway
lww04662
B cell receptor signaling pathway
lww04664
Fc epsilon RI signaling pathway
lww04714
Thermogenesis
lww04722
Neurotrophin signaling pathway
lww04810
Regulation of actin cytoskeleton
lww04910
Insulin signaling pathway
lww04912
GnRH signaling pathway
lww04915
Estrogen signaling pathway
lww04917
Prolactin signaling pathway
lww04926
Relaxin signaling pathway
lww04935
Growth hormone synthesis, secretion and action
lww05034
Alcoholism
lww05160
Hepatitis C
lww05161
Hepatitis B
lww05163
Human cytomegalovirus infection
lww05165
Human papillomavirus infection
lww05200
Pathways in cancer
lww05205
Proteoglycans in cancer
lww05206
MicroRNAs in cancer
lww05207
Chemical carcinogenesis - receptor activation
lww05208
Chemical carcinogenesis - reactive oxygen species
lww05210
Colorectal cancer
lww05211
Renal cell carcinoma
lww05213
Endometrial cancer
lww05214
Glioma
lww05215
Prostate cancer
lww05220
Chronic myeloid leukemia
lww05221
Acute myeloid leukemia
lww05223
Non-small cell lung cancer
lww05224
Breast cancer
lww05225
Hepatocellular carcinoma
lww05226
Gastric cancer
lww05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
lww00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102745822 (SOS1)
04012 ErbB signaling pathway
102745822 (SOS1)
04014 Ras signaling pathway
102745822 (SOS1)
04630 JAK-STAT signaling pathway
102745822 (SOS1)
04068 FoxO signaling pathway
102745822 (SOS1)
04072 Phospholipase D signaling pathway
102745822 (SOS1)
04151 PI3K-Akt signaling pathway
102745822 (SOS1)
04150 mTOR signaling pathway
102745822 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
102745822 (SOS1)
04540 Gap junction
102745822 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
102745822 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
102745822 (SOS1)
04660 T cell receptor signaling pathway
102745822 (SOS1)
04662 B cell receptor signaling pathway
102745822 (SOS1)
04664 Fc epsilon RI signaling pathway
102745822 (SOS1)
04062 Chemokine signaling pathway
102745822 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
102745822 (SOS1)
04912 GnRH signaling pathway
102745822 (SOS1)
04915 Estrogen signaling pathway
102745822 (SOS1)
04917 Prolactin signaling pathway
102745822 (SOS1)
04926 Relaxin signaling pathway
102745822 (SOS1)
04935 Growth hormone synthesis, secretion and action
102745822 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
102745822 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
102745822 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102745822 (SOS1)
05206 MicroRNAs in cancer
102745822 (SOS1)
05205 Proteoglycans in cancer
102745822 (SOS1)
05207 Chemical carcinogenesis - receptor activation
102745822 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
102745822 (SOS1)
05231 Choline metabolism in cancer
102745822 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
102745822 (SOS1)
05225 Hepatocellular carcinoma
102745822 (SOS1)
05226 Gastric cancer
102745822 (SOS1)
05214 Glioma
102745822 (SOS1)
05221 Acute myeloid leukemia
102745822 (SOS1)
05220 Chronic myeloid leukemia
102745822 (SOS1)
05211 Renal cell carcinoma
102745822 (SOS1)
05215 Prostate cancer
102745822 (SOS1)
05213 Endometrial cancer
102745822 (SOS1)
05224 Breast cancer
102745822 (SOS1)
05223 Non-small cell lung cancer
102745822 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
102745822 (SOS1)
05160 Hepatitis C
102745822 (SOS1)
05163 Human cytomegalovirus infection
102745822 (SOS1)
05165 Human papillomavirus infection
102745822 (SOS1)
09165 Substance dependence
05034 Alcoholism
102745822 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102745822 (SOS1)
01522 Endocrine resistance
102745822 (SOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
RasGEF
PH_19
PH_10
IQ_SEC7_PH
RHG20_PH
Motif
Other DBs
NCBI-GeneID:
102745822
NCBI-ProteinID:
XP_030892546
UniProt:
A0A7F8RH64
LinkDB
All DBs
Position
Unknown
AA seq
1120 aa
AA seq
DB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESSDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKXSF
HLVPFIIAVSFMSSSSYLPVLSKSHFLSFSSVNIFNNGYFEIFFFEFINERKTIYSFLFP
FTGSDTIFIQVSLPHGPRSASVSSISLTKGTDEVPLPPPVPPRRRPESAPAESSPSKIMS
KHLDSPPAIPPRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREPVRTPDVFSSSPLHL
QPPPLGKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLPSPPLTQEVDLPSITGPPVP
PRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS
NT seq
3363 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgcagcagctgccgtacgagtttttcagcgaggagaacgcacccaagtggcgg
gggctgctggtgccggcgctgaaaaaggtccaggggcaagttcatccgactcttgagtct
agtgatgatgctcttcaatatgttgaagaattaattttgcagttattaaatatgctatgc
caagctcagccccgaagtgcttcagatgtagaggaacgtgttcaaaaaagtttccctcat
ccaattgataagtgggcaatagctgatgcccaatcggctattgaaaagaggaagcgaaga
aaccctttatctctcccagtagaaaaaattcatcctttactaaaggaggtcctaggttat
aaaattgaccaccaggtttctgtttacatagtagctgtattagaatacatttctgcagac
attttaaagctggtggggaattatgtacgaaatatacggcattatgaaattacaaaacaa
gatattaaagtggcaatgtgtgctgataaggtattaatggacatgtttcatcaagatgta
gaagatataaatatattatctttaactgatgaagagccttccacctcaggagagcaaact
tattatgatttggtaaaagcatttatggcagaaattcgacagtacataagggaactaaat
ttaattataaaagtttttagagagccctttgtctccaactcaaaattgttttcagctaat
gatgtagaaaatatatttagtcgtatagtagatatacatgaacttagtgtaaagttactg
ggccatatagaagatactgtggaaatgactgatgaaggtagcccccatcccttagtagga
agctgctttgaagacttagctgaagaactggcatttgatccatatgaatcatatgctcga
gatattttacggcctggttttcatgatcgcttccttagtcagttatcaaagcctggagcg
gcactctatttacagtcaataggcgaaggtttcaaagaagctgttcagtatgttttaccc
aggctacttctagcccctgtttaccactgtctacattactttgaacttttgaagcagtta
gaagaaaagagtgaagatcaagaagacaaggaatgtttgaaacaagcaataacagctttg
cttaatgttcagagtggtatggaaaaaatatgttctaaaagtcttgcaaaacgaagactg
agtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaactagcaatcaag
aaaatgaacgagattcaaaagaatattgatggttgggagggaaaggacattggacagtgt
tgcaatgaatttataatggaaggaactcttacacgtgtaggagccaaacatgagagacac
atatttctctttgatggcttaatgatttgctgtaaatcaaatcatgggcagccaagactt
cctggtgctagcaatgcagaatatcgtcttaaagaaaagtttttcatgcgaaaggtacaa
attaatgacaaagatgacaccagtgagtacaagcatgcttttgaaataattttaaaagat
gaaaacagtgttatattttctgccaagtcagctgaagagaaaaacaattggatggcagca
ttgatatctttacaataccggagtacactggaaaggatgcttgatgtgacgatgctgcag
gaagagaaggaggagcagatgaggctccctagtgctgatgtttatagatttgcagagcct
gactctgaagagaatataatatttgaagaaaacatgcagcccaaggctggaattccaatt
atcaaagcgggaactgttattaaacttatagagaggctcacgtaccatatgtacgcagat
cccaattttgttcggacatttcttacaacatacagatccttttgtaaacctcaagaacta
ctgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaagctgatcgc
atagctatagagaatggagatcagcccttgagtgcagaactaaaaaggtttagaaaagaa
tacatacagcctgtacagctgcgagtattaaatgtatgtcggcattgggtagagcaccac
ttctatgattttgaaagggatgcagatcttttgcagcgaatggaagaatttattggaaca
gtgagaggtaaagcaatgaaaaaatgggttgaatccatcactaaaataatccaaaggaaa
aaaattgcaagagacaatggaccaggtcataatattacatttcagagttcacctcccaca
gttgagtggcatataagcaggcctgggcacatagagacttttgacctgctcaccttacac
ccaatagaaattgctcgacaactcactttacttgaatcagatctatatcgagctgtacag
ccatcagaattagttggaagtgtgtggacaaaagaagacaaagaaattaattctcctaat
cttctaaaaatgatccggcataccactaatctcactctgtggtttgagaagtaaagtttc
catttggttccttttatcattgctgtgtcttttatgtcatcgtcgtcctatcttcctgta
ctttctaaatcacactttctctcctttagttctgtgaacatattcaataatggctacttt
gaaatctttttctttgaatttatcaatgaaagaaaaacaatctactctttcttgtttcct
ttcacaggcagcgataccatctttatccaagtttcactgccccatggcccaagatctgct
tcagtatcgtctataagtttaaccaagggcactgatgaagtgcccctcccccctcctgtt
cctccacgaagacggccggaatctgcccccgccgaatcttcgccgtctaagattatgtct
aagcatttggacagccccccagcgattcctcctaggcagcccacatccaaagcctattca
ccacgatactcaatatcagaccggacctctatatcagaccctcctgagagccctccctta
ttaccaccgcgagagcctgtgaggacacctgatgttttctccagctccccgctacatctc
cagcctccccctttgggcaaaaaaagcgatcatggcaatgccttcttcccaaacagccct
tccccttttacaccacctcctcctcaaacaccgtctccccatggcacgagaaggcatctg
ccgtcgccaccattgacacaagaagtggaccttccttccatcactgggccgcctgttcct
ccacgacaaagcacttctcaacatatccctaaactccctccaaaaacttataaaagggag
cacacgcacccatccatgcacagagatggaccaccgctgttggagaacgcccactcctcc
tga
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