KEGG   Leptonychotes weddellii (Weddell seal): 102746046
Entry
102746046         CDS       T08708                                 
Symbol
PFKL
Name
(RefSeq) ATP-dependent 6-phosphofructokinase, liver type isoform X2
  KO
K00850  6-phosphofructokinase 1 [EC:2.7.1.11]
Organism
lww  Leptonychotes weddellii (Weddell seal)
Pathway
lww00010  Glycolysis / Gluconeogenesis
lww00030  Pentose phosphate pathway
lww00051  Fructose and mannose metabolism
lww00052  Galactose metabolism
lww01100  Metabolic pathways
lww01200  Carbon metabolism
lww01230  Biosynthesis of amino acids
lww03018  RNA degradation
lww04066  HIF-1 signaling pathway
lww04152  AMPK signaling pathway
lww04919  Thyroid hormone signaling pathway
lww04922  Glucagon signaling pathway
lww05230  Central carbon metabolism in cancer
Module
lww_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Brite
KEGG Orthology (KO) [BR:lww00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    102746046 (PFKL)
   00030 Pentose phosphate pathway
    102746046 (PFKL)
   00051 Fructose and mannose metabolism
    102746046 (PFKL)
   00052 Galactose metabolism
    102746046 (PFKL)
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03018 RNA degradation
    102746046 (PFKL)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    102746046 (PFKL)
   04152 AMPK signaling pathway
    102746046 (PFKL)
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    102746046 (PFKL)
   04919 Thyroid hormone signaling pathway
    102746046 (PFKL)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    102746046 (PFKL)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:lww01009]
    102746046 (PFKL)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:lww03019]
    102746046 (PFKL)
Enzymes [BR:lww01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.11  6-phosphofructokinase
     102746046 (PFKL)
Protein phosphatases and associated proteins [BR:lww01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     102746046 (PFKL)
Messenger RNA biogenesis [BR:lww03019]
 Prokaryotic type
  Bacterial mRNA degradation factors
   RNA degradosome components
    Other RNA degradosome components
     102746046 (PFKL)
SSDB
Motif
Pfam: PFK
Other DBs
NCBI-GeneID: 102746046
NCBI-ProteinID: XP_006749222
UniProt: A0A2U3YZP1
LinkDB
Position
Unknown
AA seq 751 aa
MNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQASWLSVSNIIQLGGTIIGSARC
KAFTTREGRLAAAYNLVQRGITNLCVIGGDGSLTGANIFRSEWGGLLEELVGAGKISEST
ARTYSHLSIVGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMG
RHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDR
NGKPISSRYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATP
DTQACVVSLSGNQSVRLPLMECVQVTKEVQKAMDEKRFEEAIQLRGRSFENNWNIYKLLA
HQKLSKEKTNFSLAILNVGAPAAGMNAAVRSAVRSGISQGHTVYVVHDGFEGLAKGQVQE
VSWHDVAGWLGRGGSMLGTKRTLPKSYMEKIVENVRTHSIHALLVIGGFEAYEGVLQLVE
ARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIV
ETMGGYCGYLATVTGIAVGADAAYVFEDPFNIQDLKANVEHMTEKMKTDIQRGLVLRNEK
CHEHYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWMSEK
LRAVYRNGRVFANAPDSACVIGLQKKAVAFSPVTELKKDTDFEHRMPREQWWLNLRLMLK
MLAHYRISMADYVSGELEHVTRRSLSIDKGF
NT seq 2256 nt   +upstreamnt  +downstreamnt
atgaacgcggctgtcagagctgtgacgcgcatgggcatttacgtgggagccaaagtcttc
ctcatctacgagggttacgagggcctcgtggaaggaggcgagaacatcaagcaggccagc
tggctcagcgtctccaacatcatccagctgggcggcaccatcattggcagtgcccgctgc
aaggccttcaccactcgggagggacgcctggcggcggcctacaacctcgtgcaacgcggc
atcaccaacctgtgtgtcatcggcggggacggcagcctcacgggtgccaacatcttccga
agcgagtggggcggcctgttggaggagctggtgggggcaggcaagatctcggagagcacg
gcgcggacgtactcgcacctgagcatcgtgggcctggtgggttccatcgacaatgacttc
tgcggcaccgacatgaccatcggcaccgactcggccctgcaccgcatcatggaggtcatc
gacgccatcaccaccaccgcccagagccaccagaggaccttcgtgctggaggtgatggga
cggcactgcgggtacctggccctggtgtccgccctggcctcgggggccgactggctgttc
atccctgaggcaccccccgaggatggctgggagaacttcatgtgtgagaggctgggtgag
actcggagcagggggtcccgactgaacatcatcatcatcgctgagggcgccattgaccgc
aacgggaagcccatctcctcccgctacgtgaaggacttggtggtccagaggctgggcttc
gacacgcgtgtgactgtgctgggccacgtgcagaggggagggaccccttcggcatttgac
cgcatcctgagcagcaagatgggcatggaggcggtcatggcgctgctggaagccacaccg
gacacgcaggcttgcgtggtcagcctctcggggaaccagtcggtgcggctgcccctcatg
gagtgcgtgcaggtgacgaaggaggtgcagaaggccatggatgagaagaggttcgaggag
gccatccagctccgcggcaggagctttgagaacaactggaacatttacaagctgcttgca
caccagaagctctccaaagagaagaccaacttctccctggccatcctgaacgtgggcgcc
ccggcggctggcatgaacgcggcggtgcgctcggccgtgcggtctggcatctcccagggc
cacacggtgtacgtcgtgcacgacggcttcgaaggcctggccaagggtcaggttcaagaa
gtgagttggcatgacgtggccggctggctgggccgtggcggctccatgctggggaccaag
aggacgctgcccaagagctacatggagaagatagtggaaaacgtccgtacccacagcatc
cacgctctgctggtcatcgggggctttgaggcctacgagggggtgctgcagctggtcgag
gcacgcgggcgctacgaggaactctgcatcgtcatgtgcgtcatcccagccaccatcagc
aacaacgtaccaggcaccgacttcagcctgggctcggacaccgctgtcaacgctgccatg
gagagctgtgaccgcatcaagcagtcggcttcggggaccaagcgccgcgtgttcatcgtg
gagaccatggggggctactgtggctacctggccacggtgacgggcatcgcagtgggcgcc
gacgccgcctacgtctttgaggaccctttcaacatccaagacttgaaagccaatgtggag
cacatgacggagaagatgaagaccgatatccagaggggcctcgtgctccgaaacgagaag
tgccatgagcactacaccacggagtttctgtataatttgtactcctctgagggaaagggc
gtgtttgactgcaggaccaacgtcctgggccacctgcagcagggcggtgctccgaccccc
tttgaccggaactacgggaccaagctcggggtgaaggccatgctctggatgtcggagaag
ctgcgggcggtctaccgcaatggacgagtgtttgccaacgcccccgattcggcctgcgtg
atcggcctgcagaagaaggcggtggctttcagccccgtcaccgagctcaagaaggacacg
gactttgagcaccgcatgccccgggagcagtggtggctgaacctgcggctcatgctgaag
atgctcgcgcattaccgcatcagcatggccgactacgtgtccggggagctggagcacgtc
acccgccgcagcctcagcatcgacaagggcttctga

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