KEGG   Leptonychotes weddellii (Weddell seal): 102746987
Entry
102746987         CDS       T08708                                 
Symbol
MAPK14
Name
(RefSeq) mitogen-activated protein kinase 14 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
lww  Leptonychotes weddellii (Weddell seal)
Pathway
lww01522  Endocrine resistance
lww04010  MAPK signaling pathway
lww04015  Rap1 signaling pathway
lww04068  FoxO signaling pathway
lww04071  Sphingolipid signaling pathway
lww04114  Oocyte meiosis
lww04148  Efferocytosis
lww04218  Cellular senescence
lww04261  Adrenergic signaling in cardiomyocytes
lww04370  VEGF signaling pathway
lww04380  Osteoclast differentiation
lww04517  IgSF CAM signaling
lww04550  Signaling pathways regulating pluripotency of stem cells
lww04611  Platelet activation
lww04613  Neutrophil extracellular trap formation
lww04620  Toll-like receptor signaling pathway
lww04621  NOD-like receptor signaling pathway
lww04622  RIG-I-like receptor signaling pathway
lww04625  C-type lectin receptor signaling pathway
lww04657  IL-17 signaling pathway
lww04658  Th1 and Th2 cell differentiation
lww04659  Th17 cell differentiation
lww04660  T cell receptor signaling pathway
lww04664  Fc epsilon RI signaling pathway
lww04668  TNF signaling pathway
lww04670  Leukocyte transendothelial migration
lww04714  Thermogenesis
lww04722  Neurotrophin signaling pathway
lww04723  Retrograde endocannabinoid signaling
lww04728  Dopaminergic synapse
lww04750  Inflammatory mediator regulation of TRP channels
lww04912  GnRH signaling pathway
lww04914  Progesterone-mediated oocyte maturation
lww04917  Prolactin signaling pathway
lww04926  Relaxin signaling pathway
lww04932  Non-alcoholic fatty liver disease
lww04933  AGE-RAGE signaling pathway in diabetic complications
lww04935  Growth hormone synthesis, secretion and action
lww04936  Alcoholic liver disease
lww05014  Amyotrophic lateral sclerosis
lww05020  Prion disease
lww05022  Pathways of neurodegeneration - multiple diseases
lww05132  Salmonella infection
lww05133  Pertussis
lww05135  Yersinia infection
lww05140  Leishmaniasis
lww05142  Chagas disease
lww05145  Toxoplasmosis
lww05152  Tuberculosis
lww05161  Hepatitis B
lww05163  Human cytomegalovirus infection
lww05167  Kaposi sarcoma-associated herpesvirus infection
lww05169  Epstein-Barr virus infection
lww05170  Human immunodeficiency virus 1 infection
lww05171  Coronavirus disease - COVID-19
lww05205  Proteoglycans in cancer
lww05208  Chemical carcinogenesis - reactive oxygen species
lww05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
lww05415  Diabetic cardiomyopathy
lww05417  Lipid and atherosclerosis
lww05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:lww00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102746987 (MAPK14)
   04015 Rap1 signaling pathway
    102746987 (MAPK14)
   04370 VEGF signaling pathway
    102746987 (MAPK14)
   04668 TNF signaling pathway
    102746987 (MAPK14)
   04068 FoxO signaling pathway
    102746987 (MAPK14)
   04071 Sphingolipid signaling pathway
    102746987 (MAPK14)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    102746987 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    102746987 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    102746987 (MAPK14)
   04218 Cellular senescence
    102746987 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    102746987 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102746987 (MAPK14)
   04613 Neutrophil extracellular trap formation
    102746987 (MAPK14)
   04620 Toll-like receptor signaling pathway
    102746987 (MAPK14)
   04621 NOD-like receptor signaling pathway
    102746987 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    102746987 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    102746987 (MAPK14)
   04660 T cell receptor signaling pathway
    102746987 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    102746987 (MAPK14)
   04659 Th17 cell differentiation
    102746987 (MAPK14)
   04657 IL-17 signaling pathway
    102746987 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    102746987 (MAPK14)
   04670 Leukocyte transendothelial migration
    102746987 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    102746987 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    102746987 (MAPK14)
   04917 Prolactin signaling pathway
    102746987 (MAPK14)
   04926 Relaxin signaling pathway
    102746987 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    102746987 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102746987 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    102746987 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    102746987 (MAPK14)
   04722 Neurotrophin signaling pathway
    102746987 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102746987 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102746987 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    102746987 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    102746987 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    102746987 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102746987 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102746987 (MAPK14)
   05161 Hepatitis B
    102746987 (MAPK14)
   05171 Coronavirus disease - COVID-19
    102746987 (MAPK14)
   05163 Human cytomegalovirus infection
    102746987 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102746987 (MAPK14)
   05169 Epstein-Barr virus infection
    102746987 (MAPK14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102746987 (MAPK14)
   05135 Yersinia infection
    102746987 (MAPK14)
   05133 Pertussis
    102746987 (MAPK14)
   05152 Tuberculosis
    102746987 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102746987 (MAPK14)
   05140 Leishmaniasis
    102746987 (MAPK14)
   05142 Chagas disease
    102746987 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    102746987 (MAPK14)
   05020 Prion disease
    102746987 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    102746987 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102746987 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    102746987 (MAPK14)
   05415 Diabetic cardiomyopathy
    102746987 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102746987 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    102746987 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102746987 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102746987 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lww01001]
    102746987 (MAPK14)
Enzymes [BR:lww01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     102746987 (MAPK14)
Protein kinases [BR:lww01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   102746987 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 102746987
NCBI-ProteinID: XP_030890181
UniProt: A0A7F8RAG7
LinkDB
Position
Unknown
AA seq 333 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGADLLKKISSESARNYIQSLTQMPKMNFANVFIGANPLGHICHLRLEGMAPYSFPPPS
LLGSLAEGCDSGSCRTCTALAKKGVDLFLKFGG
NT seq 1002 nt   +upstreamnt  +downstreamnt
atgtctcaggagaggcccacgttctaccggcaggagctgaacaagacaatctgggaggtg
cccgagcgttaccagaatctgtccccggtgggctccggtgcctatggctccgtgtgtgct
gcttttgacacaaaaaccgggttacgtgtggcagtgaagaagctctccagaccatttcag
tccattattcatgccaaaaggacctacagagaactgcggttacttaaacatatgaaacat
gaaaatgtgattggtctgttggatgtttttacacctgcaaggtctctggaggaattcaat
gatgtgtatctggtcacccatctcatgggagcagatctgaacaacattgtgaaatgtcag
aagcttacagatgaccatgttcagttcctcatctaccagattctccgaggtctcaagtat
atacattcagctgacataattcacagggacctaaaacctagtaatctagctgtgaatgaa
gactgtgagctgaagatcttggattttggactggcccgacatacagatgatgaaatgaca
ggctatgtggccaccaggtggtaccgggctcctgagatcatgctgaactggatgcattac
aaccagacagttgatatttggtcagtgggatgcataatggccgagctgttgactggaaga
acgttgtttcctggtacagaccatattgatcagttgaagctcattttaagactcgttgga
accccaggggctgatcttttgaagaaaatctcctcagagtctgcaagaaactacattcag
tctttgacccagatgccgaaaatgaactttgcaaatgtatttattggcgccaatcccttg
gggcacatttgccacctcagacttgaaggaatggctccatattccttcccgccaccatca
cttctgggatccttggcagagggatgtgacagtggtagctgcaggacatgtactgccttg
gctaagaagggagttgatttattccttaaatttgggggctaa

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