KEGG   Leptonychotes weddellii (Weddell seal): 102747848
Entry
102747848         CDS       T08708                                 
Symbol
NOTCH1
Name
(RefSeq) neurogenic locus notch homolog protein 1
  KO
K02599  Notch 1
Organism
lww  Leptonychotes weddellii (Weddell seal)
Pathway
lww01522  Endocrine resistance
lww04330  Notch signaling pathway
lww04658  Th1 and Th2 cell differentiation
lww04919  Thyroid hormone signaling pathway
lww05020  Prion disease
lww05165  Human papillomavirus infection
lww05200  Pathways in cancer
lww05206  MicroRNAs in cancer
lww05224  Breast cancer
Brite
KEGG Orthology (KO) [BR:lww00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    102747848 (NOTCH1)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    102747848 (NOTCH1)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    102747848 (NOTCH1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102747848 (NOTCH1)
   05206 MicroRNAs in cancer
    102747848 (NOTCH1)
  09162 Cancer: specific types
   05224 Breast cancer
    102747848 (NOTCH1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    102747848 (NOTCH1)
  09164 Neurodegenerative disease
   05020 Prion disease
    102747848 (NOTCH1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102747848 (NOTCH1)
SSDB
Motif
Pfam: EGF hEGF EGF_TEN EGF_CA EGF_2 Ank_2 Ank NOD NODP Ank_4 Ank_5 Ank_3 EGF_3 EGF_Teneurin JAG1-like_EGF2 EGF_DL_JAG
Other DBs
NCBI-GeneID: 102747848
NCBI-ProteinID: XP_030878105
UniProt: A0A7F8QA49
LinkDB
Position
Unknown
AA seq 2170 aa
MHVQAEATQGGRAEDARLQEQVLGVLEAGPGPRGAAPVPQEAALVTMGCSDSGAGALLAG
GALSLAAVAFSHELGGADLSSCPSPGLRCSQPSESCLNGGKCEVFPNGTEACVCSGAFVG
QRCQAPSPCLSAPCKNAGTCHVVDRGGLVDYICTCRLGFSGPLCLTPQDNACLSTPCRNG
GTCDLLTLTEYKCRCPPGWSGKTCQQADPCASNPCANGGQCLPFEASYICGCPHGFHGPT
CRQDVNECSQNPRLCQNGGTCHNEVGSYRCTCRTAHTGPHCELPYVPCSPSPCQNGGTCR
PTGDTTHECACLPGFTGQNCEENVDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTE
DVDECQLMPNACQNGGTCHNSHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRV
ASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVD
ECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECISNPCQNEATCLDQIGEF
QCICMPGYEGVHCEVNTDECASSPCLQNGRCLDKINEFLCECSTGFTGHLCQYDVDECAS
TPCKNGAKCLDGPNTYTCVCTEGYTGPHCEVDIDECDPDPCHYGVCKDGVATFTCLCRPG
YTGHHCESNINECHSQPCRHGGTCQDRDNAYLCSCLKGTTGPNCETNLDDCVSSPCDSGT
CLDKIDGYECACEPGYTGSMCNVNIDECAGNPCHHGGTCEDGVNSFTCRCPEGYHGPTCL
SEVNECSSDPCIHGACRDSLNGYKCDCDPGWSGANCDVNNDECESNPCANGGACRDMTSG
YVCTCREGFSGPNCQTNINECASNPCLNQGSCIDDVAGYKCNCPLPYTGATCEVVLAPCA
PGPCRNGGVCKESEDYESFSCICPTGWQGQTCEVDINECVKSPCRNGASCQNTNGGYRCR
CRAGYTGHNCETDVDDCRPNPCHNGGSCTDGVNTAFCDCLPGFRGPFCEEDINECASNPC
RHGANCTDCVDSYTCTCPTGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFT
GSYCQHDVNECDSRPCLHGGTCQDSYGTYKCTCPQGYTGLNCQVSQRATGGPGRSPLYDQ
YCKDHFGDGHCDQGCNSAECEWDGLDCAEHVPERLAAGALVLVVLTPPAQLRNNSLHFLR
ELSRLLHTNVVFKRDAHGQPMIFPYYGREEELRKHPIKRAADAWAAPGALLDRVEAALLP
RGLAGRRRRELDPMDIRGSIVYLEIDNRQCVQSSSQCFQSATDVAAFLGALASLGSLNIP
YKIEAVQSETVEPPPPPQLHFMYVAVAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKV
SEASKKKRREPLGEDSVGLKPLKNASDGALMDDNQNEWGDEDLEAKKFRFEEPVVLPDLD
DQTDHRQWTQQHLDAADLRVSAMAPTPPQGEADTDCMDVNVRGPDGFTPLMIASCSGGGL
ETGNSEEEEDAPAVISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADAN
IQDNMGRTPLHAAVSADAQGVFQILIRNRATDLDARMHDGTTPLILAARLAVEGMLEDLI
NSHADVNAVDDLGKSALHWAAAVNNVEAAVVLLKNGANKDMQNNKEETPLFLAAREGSYE
TAKVLLDHFANRDITDHMDRLPRDIAQERMHHDIVRLLDEYSLVRSPQLHGPALGGAPTL
SPPLCSPNGYLGNLKPAVPGKKARKPSTKGLACGGKEAKDLKARRKKSQDGKGCLLDSSS
VLSPVDSLESPHGYLSDVASPPLLSSPFQQSPSVPLSHLPGMPDAHLGAGHLSVAAKPEM
AALGAGGRLAFEAGPPRLSHLPVASSTGAVLGTAGAGGGGGAVNFTVGGTVGGAAGLNGQ
CEWLSRLQNGLMPNQYNPLRGNVASGPLSTQAPALQHGMMGPLHAGLSTTAALSQMMSYQ
ALPNTRLAGQPHLVQTQPLQQVQQQQQNLQLQQPGLQPPNVQQPQGLPPQPHLSVSSAAG
GHLGRSFLGGEPSQADVQPLGPSSLAVHTILPQDSQALPTALPATLAPPMTTAQFLTPPS
QHSYSSSPADNTPSHQLQVPEHPFLTPSPESPDQWSSSSPHSHVSDWSEGISSPPTSTQS
HIAHIPEALK
NT seq 6513 nt   +upstreamnt  +downstreamnt
atgcacgtccaggccgaggcgacgcagggcggtcgcgctgaagatgcccgcctgcaggag
caggtattgggtgtcctggaggctgggccaggtccccgaggtgcagcccctgtgccccag
gaggcggccctggtgacaatgggctgctctgattccggggctggcgctttgttggcgggc
ggggccttgagccttgcagctgtcgccttttcccacgagctggggggggctgacctctcg
tcttgcccctccccaggcctgcgatgttcccagcccagtgagagctgcttgaatggcggg
aagtgtgaagtgttccccaacggcactgaagcctgtgtctgcagcggggccttcgtgggc
cagcgatgccaggcacccagcccctgcctcagcgccccctgcaagaacgccgggacgtgc
cacgtggtggaccgcggaggcctggtcgactacatctgcacctgccgcctgggcttctcc
gggcccctctgcctgacgccccaagacaacgcctgcctctccaccccctgtcgcaacggg
ggcacctgtgacctgctcacgctcaccgagtacaagtgccgctgccccccgggctggtca
gggaagacgtgccagcaggccgacccgtgcgcctccaacccctgtgccaatggcggccag
tgcctgcccttcgaggcttcatacatctgcggctgcccgcacggcttccacggccccacc
tgcaggcaggacgtgaatgagtgcagccagaaccccaggctctgccaaaacgggggcacc
tgccacaacgaggttggctcctaccgctgcacctgccgtaccgcccacaccggcccccac
tgcgagctgccctacgtgccctgcagcccctccccctgccagaacgggggcacctgccgc
cccacgggggacaccacccacgagtgcgcctgcctgccaggcttcaccggccagaactgc
gaggagaacgtggatgactgtcccggcaacaattgcaagaacggaggtgcttgcgtggac
ggcgtaaacacctacaactgccgctgtcccccagagtggacaggtcagtactgcaccgag
gacgtggacgagtgccagctcatgcccaacgcctgccagaacggcggcacctgccacaac
agccacgggggctataactgcgtgtgcgtcaacggctggacgggcgaggactgcagcgag
aacattgacgactgcgccagcgccgcctgcttccacggcgccacctgccacgaccgcgtg
gcctccttctactgcgagtgtccccacggccgcacgggcctgctctgccacctgaacgac
gcctgcatcagcaacccttgcaacgagggctccaactgcgacaccaaccccgtgaacggc
aaagccatctgcacctgcccctcggggtacacggggccggcctgcagccaggacgtggac
gagtgctcgctgggtgccaacccctgtgagcacgcgggcaagtgcatcaacacgctgggc
tccttcgagtgccagtgtctacaaggctacaccggcccccgctgcgagatcgacgtcaat
gagtgcatctcgaacccgtgtcagaatgaggccacctgcctggaccagatcggggagttc
cagtgcatctgcatgcccggctacgagggcgtgcactgtgaggtcaacacagacgagtgt
gccagtagcccctgtctccagaacggccgctgcctggacaaaatcaacgagtttctgtgc
gagtgctccacgggcttcaccggacatctgtgtcagtatgacgtggacgagtgtgcaagc
acgccctgcaagaacggcgccaagtgcctggacgggcccaacacctacacctgcgtgtgc
acagaaggctacacggggccgcactgcgaggtggacatcgacgagtgtgaccccgatccc
tgccactatggggtgtgcaaggacggggtggccaccttcacctgcctgtgccggccgggc
tatacgggccaccactgcgagagcaacatcaacgagtgtcacagccagccctgtcggcac
ggcggcacctgccaggaccgcgacaacgcctatctctgctcctgcctcaaggggaccaca
ggacccaactgtgagacgaacctggacgactgcgtcagcagcccctgcgactcgggcacg
tgcctggacaagatcgacggctacgagtgtgcgtgcgagcctggctacacggggagcatg
tgcaacgtgaacatcgacgagtgcgcgggcaacccctgccaccacgggggtacctgtgag
gacggtgtcaacagcttcacgtgccgctgccccgagggctaccacggccccacgtgcctg
tccgaggtcaacgagtgcagcagcgacccctgcatccacggggcctgccgggacagcctc
aacgggtacaagtgtgactgtgaccccgggtggagcggggccaactgtgacgtgaacaac
gacgagtgtgagtccaacccgtgtgcgaacggaggcgcctgccgagacatgaccagcggc
tacgtgtgcacctgccgcgagggcttcagtggccccaactgccaaaccaacatcaacgag
tgtgcgtccaacccgtgcctgaaccagggctcgtgcatcgatgacgtggccgggtacaag
tgcaactgtccgctgccctacacaggagccacgtgcgaggtggtgctggccccgtgcgcc
cccggcccctgcagaaacgggggtgtgtgcaaagagtctgaggactatgagagtttctcc
tgcatctgccccacgggctggcaaggacagacctgtgaggtcgacattaacgagtgtgtg
aagagcccgtgccgcaacggggcctcgtgccagaacactaacggcggctatcgttgccgc
tgccgcgcaggctacacggggcacaactgcgagacggacgtggacgactgccggccaaat
ccatgccacaacggcggttcctgcaccgacggcgtcaacaccgctttctgcgactgcctg
cccggcttccgggggcccttctgcgaggaggacatcaacgagtgcgccagcaacccatgc
cgccacggggccaactgcacggactgcgtggacagctacacctgcacctgccccacgggc
ttcagcgggatccactgtgagaacaacacgcccgactgcacagagagctcttgctttaat
ggcggcacctgtgtggatggcatcaactccttcacctgcctgtgtccgccgggcttcacg
ggcagctactgtcagcacgacgtcaacgagtgcgactcgcggccctgcctgcacggcggc
acctgccaggacagctacgggacctacaagtgcacctgcccgcagggctacacgggcctc
aactgccaggtgagccagcgggctacaggggggcccggcaggagccccctgtacgaccag
tactgcaaggaccacttcggcgacgggcactgcgaccagggctgcaacagcgccgagtgc
gagtgggacgggctggactgcgcggagcacgtgcccgagcggctggcggccggcgcgctg
gtgctggtcgtgctgaccccgcccgcgcagctgcgcaacaactcgctgcacttcctgcgg
gagctcagtcgcctgctgcacaccaacgtggtgttcaagcgcgacgcccatggccagccc
atgatcttcccgtactacggccgcgaggaggagctgcgcaaacaccccatcaagcgcgcg
gcggacgcctgggccgcgcctggggccctgctcgaccgggtggaggccgccctgctcccg
cggggcctggcgggccgccggcgcagggagctggaccccatggacatccgcggatccatc
gtctacctggagatcgacaaccggcagtgtgtccagtcctcctcacaatgcttccagagc
gccacggacgtggccgccttcctgggcgcacttgcctcactggggagcctcaacatccct
tataagatcgaggccgtgcagagtgagaccgtggagccgcccccgcccccgcagctgcac
ttcatgtacgtggctgtggccgccttcgtgctgctcttcttcgtgggctgtggggtgctg
ctgtcccggaagcgccggcggcagcatggacagctctggttccccgaaggcttcaaggtc
tcagaggccagcaagaagaagcggcgggagcccctcggcgaggactccgtgggcctcaag
cccctgaagaatgcctcagatggcgctctcatggacgacaaccagaacgagtggggggat
gaggacctggaggccaaaaagttccggttcgaggagccggtggttcttcctgacctggat
gaccagacagaccaccggcaatggacccagcagcacctggacgctgccgacctgcgtgtg
tcggccatggcccccacaccaccccagggcgaagctgacactgactgcatggacgtcaac
gtccgagggccagacggcttcacgcccctcatgatcgcctcctgcagcggagggggcctg
gagacgggcaacagcgaggaggaggaggacgcgccggccgtcatctctgacttcatctac
cagggtgccagtctgcacaaccagacagaccgcactggcgagaccgccctgcacctggcc
gcccgctactcgcgctccgacgcggccaagcgcctgctggaggccagcgcagacgccaac
atccaggacaacatgggacgcaccccgctgcacgccgccgtgtctgccgacgcgcaggga
gtcttccagatcctcatccggaaccgggccacggacctggacgcccgtatgcacgatggc
acgacaccgctgatcctggcggcccgcctggctgtcgagggcatgctggaggacctgatc
aactcgcacgccgacgtcaatgccgtggacgacctgggcaagtctgccctgcactgggcc
gccgccgtgaataacgtggaggctgccgtcgtgcttctgaagaacggggccaacaaagac
atgcagaacaacaaggaggagacgcccctgttcctggctgctcgggagggcagctacgag
accgccaaggtgctgctggaccacttcgccaaccgggacatcacagaccacatggaccgc
ctgcctcgcgacattgctcaggagcgtatgcaccacgacatcgtgcggctgctggatgag
tacagcctggtgcgcagcccccagctgcacggccctgccctgggcggtgcgcccaccctg
tccccgccgctctgctctcccaacggctacctgggcaacctcaagccggccgtgccgggc
aagaaggcccgcaagcccagcaccaagggcctggcctgtggcggcaaggaggccaaggac
ctcaaggcgcgcaggaagaaatcccaggacggcaagggctgcctgctggacagctcgagc
gtgctgtcgcccgtggactcccttgagtcgccccacggctacctgtcggacgtggcctcg
ccgcccctcctgtcctctccgttccagcagtccccgtccgtgcccctgagccacttgccc
ggcatgcctgacgcccacctgggtgctggccacctgagcgtggctgccaagcccgagatg
gcagcgctgggtgcgggtggccggctggcctttgaggcgggaccgccgcggctctcccac
ctgcccgtggcctccagcaccggcgccgtcctgggcaccgcaggtgctggcggcggaggc
ggggccgtgaatttcaccgtgggcgggaccgtgggcggggccgcgggcttgaacggccag
tgcgagtggctgtcccggctgcagaacggcctgatgccaaaccagtacaacccgctgcga
gggaacgtggcgtcgggccccctgagcacgcaggcccctgccctgcagcacggaatgatg
ggcccgctgcatgccggcctctccaccacggccgccctgtcgcagatgatgagctaccag
gccctgcccaacacgcgcctggccggccagccgcacctggtgcagacccagccgctgcag
caggtgcagcaacagcaacagaacttgcagctgcagcagcccggcctgcagccgcccaac
gtccagcagccgcagggcctgccgccccagccgcacctcagcgtgagctcggccgccggc
ggccacctgggccggagcttcctgggcggggagccgagccaggcggacgtgcagccgctg
ggccccagcagcctggcggtgcacaccatcctgccgcaggacagccaggccctgcccacc
gccctgcccgccacgctggccccgcccatgaccacggctcagttcctgaccccgccctcg
cagcacagctactcttcctcgccggcggacaacacccccagccaccagctgcaggtgcct
gagcaccccttcctcaccccgtcccccgagtccccggaccagtggtccagctcgtcacca
cattcccacgtctctgactggtctgagggcatctccagcccgcccaccagcacgcagtcc
cacatcgcgcacattccggaggcgctcaagtaa

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