Leptonychotes weddellii (Weddell seal): 4355828 Help Entry 4355828           CDS       T08708                                  Symbol COX1 Name (RefSeq) cytochrome c oxidase subunit I   KO K02256   cytochrome c oxidase subunit 1 [EC:7.1.1.9] Organism lww  Leptonychotes weddellii (Weddell seal) Pathway lww00190   Oxidative phosphorylation lww01100   Metabolic pathways lww04260   Cardiac muscle contraction lww04714   Thermogenesis lww04932   Non-alcoholic fatty liver disease lww05010   Alzheimer disease lww05012   Parkinson disease lww05014   Amyotrophic lateral sclerosis lww05016   Huntington disease lww05020   Prion disease lww05022   Pathways of neurodegeneration - multiple diseases lww05208   Chemical carcinogenesis - reactive oxygen species lww05415   Diabetic cardiomyopathy Module lww_M00154   Cytochrome c oxidase Brite KEGG Orthology (KO) [BR:lww00001]  09100 Metabolism   09102 Energy metabolism    00190 Oxidative phosphorylation     4355828 (COX1)  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     4355828 (COX1)   09159 Environmental adaptation    04714 Thermogenesis     4355828 (COX1)  09160 Human Diseases   09161 Cancer: overview    05208 Chemical carcinogenesis - reactive oxygen species     4355828 (COX1)   09164 Neurodegenerative disease    05010 Alzheimer disease     4355828 (COX1)    05012 Parkinson disease     4355828 (COX1)    05014 Amyotrophic lateral sclerosis     4355828 (COX1)    05016 Huntington disease     4355828 (COX1)    05020 Prion disease     4355828 (COX1)    05022 Pathways of neurodegeneration - multiple diseases     4355828 (COX1)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     4355828 (COX1)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     4355828 (COX1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03029 Mitochondrial biogenesis [BR:lww03029]     4355828 (COX1) Enzymes [BR:lww01000]  7. Translocases   7.1  Catalysing the translocation of protons    7.1.1  Linked to oxidoreductase reactions     7.1.1.9  cytochrome-c oxidase      4355828 (COX1) Mitochondrial biogenesis [BR:lww03029]  Mitochondrial DNA transcription, translation, and replication factors   Mitochondrial DNA-encoded proteins    Cytochrome c oxidase     4355828 (COX1) SSDB OrthologParalogGFIT Motif Pfam:  COX1 Motif Other DBs NCBI-GeneID:  4355828 NCBI-ProteinID:  YP_778801 UniProt:  Q08HA8 LinkDB All DBs Position MT AA seq 514 aa AA seqDB search MFMNRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGALLGDDQIYNVIVTA HAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEA GAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQ IPLFVWSVLITAVLLLLSLPVLAAGITMLLSDRNLNTTFFDPAGGGDPILYQHLFWFFGH PEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVD TRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMLWALGFIFLFTVGGLTGIVLAN SSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGFTLDDTWAKIHFTIMFVG VNMTFFPQHFLGLSGMPRRYSDYPDAYTTWNTVSSMGSFISLTAVMLMVFMIWEAFASKR EVATVELTTTNIEWLHGCPPPYHTFEEPTYVVLK NT seq 1545 nt NT seq  +upstreamnt  +downstreamnt atgttcataaaccgatgactattttccacaaaccacaaagatattggtactctctatcta ttatttggtgcatgagccggtatagtaggtaccgccctcagtcttttaattcgcgcagaa ctaggacaacctggtgctttactaggagatgatcagatttataacgtgattgtcaccgcc cacgcattcgtaataatctttttcatagtaatacctatcataatcggaggcttcggaaac tgattagtacccctaataatcggcgctcctgacatagcattcccccgaataaacaatata agcttctgactcttaccgccatctttcctactactactggcctcctccatagtagaagca ggcgcaggaacaggatgaaccgtatatcctcccttagctggtaacctagcccacgcagga gcatctgtagacctgacgattttctcccttcacctagcaggtgtatcatccatccttggg gctattaatttcatcactactatcatcaatataaaacctcctgcaatatctcaatatcaa attcccctattcgtgtgatccgtactaatcacagcagtactcctactactatcactacca gttctagcagctggcattactatactactttcagatcgaaacctgaatacaacattcttt gaccccgctggaggaggggatcctattctatatcaacacctattctgattctttggacat cctgaagtttacatcctaatcctcccaggattcggaatgatttcacatatcgttacctac tactcagggaaaaaagaaccctttggttatataggaatagtatgagcaataatatccatc ggcttcctaggtttcatcgtatgggcccaccatatatttaccgtaggaatggatgttgat acacgagcatacttcacttcagccactataatcattgcaatcccaacaggagtaaaagta tttagctgactagctaccctacatggaggcaacatcaagtgatccccagctatactatga gccctagggtttattttcctattcacagtagggggtcttacgggcatcgtactagcaaac tcgtcactggacatcgtactccacgacacatactatgtagtagcacacttccactacgtc ttatcaataggagcagtcttcgctatcataggcggatttgttcactgattccccctattc tcaggcttcactcttgacgacacttgagcaaaaattcactttacaattatatttgttggg gttaacataacattcttcccccaacatttcttaggcttatcaggaatacctcgacgatac tccgactacccagacgcctacacaacatgaaacacagtgtcctctataggctcatttatt tcacttacagcagtaatactaatagtattcatgatctgagaagccttcgcatccaaacga gaagtagcaacagttgaattaactacgactaatatcgaatgactgcacggatgtcctcct ccctatcacacatttgaagaacctacttatgttgtactaaaataa

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