KEGG   Leptonychotes weddellii (Weddell seal): 4355832
Entry
4355832           CDS       T08708                                 
Symbol
ND1
Name
(RefSeq) NADH dehydrogenase subunit 1
  KO
K03878  NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
Organism
lww  Leptonychotes weddellii (Weddell seal)
Pathway
lww00190  Oxidative phosphorylation
lww01100  Metabolic pathways
lww04714  Thermogenesis
lww04723  Retrograde endocannabinoid signaling
lww05010  Alzheimer disease
lww05012  Parkinson disease
lww05014  Amyotrophic lateral sclerosis
lww05016  Huntington disease
lww05020  Prion disease
lww05022  Pathways of neurodegeneration - multiple diseases
lww05208  Chemical carcinogenesis - reactive oxygen species
lww05415  Diabetic cardiomyopathy
Module
lww_M00142  NADH:ubiquinone oxidoreductase, mitochondria
Brite
KEGG Orthology (KO) [BR:lww00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    4355832 (ND1)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    4355832 (ND1)
  09159 Environmental adaptation
   04714 Thermogenesis
    4355832 (ND1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    4355832 (ND1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    4355832 (ND1)
   05012 Parkinson disease
    4355832 (ND1)
   05014 Amyotrophic lateral sclerosis
    4355832 (ND1)
   05016 Huntington disease
    4355832 (ND1)
   05020 Prion disease
    4355832 (ND1)
   05022 Pathways of neurodegeneration - multiple diseases
    4355832 (ND1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    4355832 (ND1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis [BR:lww03029]
    4355832 (ND1)
Enzymes [BR:lww01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     4355832 (ND1)
Mitochondrial biogenesis [BR:lww03029]
 Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial DNA-encoded proteins
   Mitochondrial respiratory chain complex I
    4355832 (ND1)
SSDB
Motif
Pfam: NADHdh
Other DBs
NCBI-GeneID: 4355832
NCBI-ProteinID: YP_778799
UniProt: Q08HB0
LinkDB
Position
MT
AA seq 318 aa
MFMINIASLIIPILLAVAFLTLVERKVLGYMQLRKGPNIVGPYGLLQPIADAVKLFTKEP
LRPLTSSTSMFIMAPILALTLALTMWIPLPMPYPLINMNLGVLFMLAMSSLAVYSILWSG
WASNSKYALIGALRAVAQTISYEVTLAIILLSVLLMNGSFTLSTLITTQEHLWLIFPAWP
LAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFAMFFLAEYANIIMMNIFTTL
LFFGAFHAPYMPELYTINFTMKTLMLTILFLWIRASYPRFRYDQLMHLLWKNFLPLTLAL
CMWHVTLPIISASIPPQT
NT seq 957 nt   +upstreamnt  +downstreamnt
atgtttataatcaacattgcatcactaattatcccaatcctccttgccgtagctttccta
acattagtagaacgaaaagtactaggctacatacaactccgaaaaggacccaacatcgta
ggaccctacggactccttcaacctatcgcagacgctgtaaaactatttaccaaagaacct
ttacgaccactaacatcctctacatctatatttattatagcccccattctagccctaacc
ctagccctaacaatatgaatccccttacccataccataccccctcatcaacataaaccta
ggagtactatttatgctagcaatatcaagcctagccgtctactcaatcctatgatccgga
tgagcttcaaactccaaatacgccctaatcggagccctacgagccgtagcccaaacaatc
tcatacgaagttaccctagccatcatcttactatcagtactactaataaacggatctttc
accctatcaacactaatcaccactcaagaacatctatgactaattttccctgcatgacca
ctagccataatatgattcatctccaccctagcagaaaccaaccgtgccccatttgaccta
acagaaggagaatcagaactcgtctcaggattcaacgtagaatacgcagcaggcccattc
gccatgtttttcctagcagaatacgccaacatcattataataaatattttcacaaccctc
ctattctttggagcattccacgctccatacatacctgaactctacaccattaacttcacc
ataaaaaccctaatactaacaatcctattcctatgaatccgagcatcatacccacgattt
cgatacgaccaactaatacacctcctatgaaaaaatttcctaccccttacactagcccta
tgcatatgacacgtaacactacccattatttcagcaagcattcctccccaaacataa

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