Lentzea xerophila: ACRSBM_04095
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Entry
ACRSBM_04095 CDS
T11210
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
lxr Lentzea xerophila
Pathway
lxr00290
Valine, leucine and isoleucine biosynthesis
lxr00660
C5-Branched dibasic acid metabolism
lxr01100
Metabolic pathways
lxr01110
Biosynthesis of secondary metabolites
lxr01210
2-Oxocarboxylic acid metabolism
lxr01230
Biosynthesis of amino acids
Module
lxr_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
lxr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
ACRSBM_04095 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ACRSBM_04095 (leuC)
Enzymes [BR:
lxr01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
ACRSBM_04095 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
ACRSBM_04095 (leuC)
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Gene cluster
GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
XWW35808
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All DBs
Position
826238..827644
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AA seq
468 aa
AA seq
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MSRTLAEKVWEAHVVRHGSGAEPDLLYIDLHLLHEVTSPQAFDGLRLAGRRLRRPDLTIA
TEDHNVPTVDIDKPIADLVSRTQVETLRRNCAEFGVRLHPMGDFEQGIVHVVGPQLGLTQ
PGMTVVCGDSHTSTHGAFGALAFGIGTSEVEHVMATQTLPLRPFKTMSITVDGELGPGVT
AKDIILAVIAKIGTGGGQGYVLEYRGSAIENLSMEARMTVCNMSIEAGARAGMIAPDETT
FEYIKGRPHAPSGADWDAAVEYWKTLRTDDDATFDAEVRISADELTPFVTWGTNPGQGLP
LSATVPDPEQIVDENERVAAEKALTYMGLEPGTPLRDIRVDTVFLGSCTNGRIEDLRAAA
DVLKGKHVATGVRMLVVPGSMRVRKQAEDEGLDKVFLDAGAEWRQAGCSMCLGMNPDQLA
PGERSASTSNRNFEGRQGKGGRTHLVSPLVAAATAVRGTLSAPADLEN
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
atgagccgcacgctcgcggagaaggtgtgggaggcacacgttgtgcgccacggaagtggt
gcggagccggacctgctctacatcgacctgcacctgctgcacgaagtcaccagcccccag
gcgttcgacgggctgcgccttgccggccgcaggctgcgcaggcccgatctcacgatcgcc
actgaggatcacaacgtcccgaccgtcgacatcgacaagccgatcgcggatctggtgtcg
cgcacgcaggtcgagacgctcaggcgcaactgcgcggagttcggggtgcggctgcacccc
atgggggacttcgagcagggcatcgtccacgtcgtgggcccgcagctcggcctcacgcag
cccggcatgacggtggtgtgcggcgatagtcacacgagcacgcacggagcgttcggcgcg
ctggcgttcggcatcggcacgtccgaggtcgagcacgtgatggcgacgcagacgttgccg
ttgcgtccgttcaagacgatgtccatcaccgtcgacggcgagctcggccccggcgtgacg
gcgaaggacatcatcctcgcggtcatcgcgaagatcggaaccggtggcggacagggctat
gtgctcgagtaccgcggctcggccatcgagaacctttcgatggaagcgcgcatgaccgtc
tgcaacatgtcgatcgaagcgggtgcgcgcgccggcatgatcgcgccggacgagacgact
ttcgagtacatcaagggtcgtccgcacgcaccgtccggcgcggactgggacgcggccgtg
gagtactggaagacgctgcgcaccgacgacgacgcgactttcgacgccgaggtgcgcatc
tccgccgacgagctcacgccgttcgtcacgtggggcaccaaccccggccaggggctgccc
ctgagcgcgaccgtccccgaccccgagcagatcgtggacgagaacgagcgcgtggccgcc
gagaaggcgctgacgtacatgggcctcgagcccggcacgccgctgcgcgacatccgcgtg
gacaccgtcttccttggctcgtgcaccaacgggcgcatcgaggacctgcgcgccgcggcg
gacgtgctcaagggcaagcacgtcgctactggagtacggatgctggtcgtccccggttcg
atgcgggtgcgcaagcaggccgaggacgagggcctggacaaggtcttcctcgacgcgggc
gccgagtggcggcaggccggctgctcgatgtgtcttggcatgaacccggatcagctcgcg
cccggcgagcgcagcgcctcgacctccaaccgcaacttcgagggcaggcagggcaagggc
ggcaggacgcacctcgtgtcaccgctcgtcgccgctgccacggccgtgcgcggcaccctg
tcggcccccgcagacctggagaactga
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