Marilutibacter alkalisoli: FKV23_02610
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Entry
FKV23_02610 CDS
T06167
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
lyj
Marilutibacter alkalisoli
Pathway
lyj00260
Glycine, serine and threonine metabolism
lyj00261
Monobactam biosynthesis
lyj00270
Cysteine and methionine metabolism
lyj00300
Lysine biosynthesis
lyj01100
Metabolic pathways
lyj01110
Biosynthesis of secondary metabolites
lyj01120
Microbial metabolism in diverse environments
lyj01230
Biosynthesis of amino acids
Module
lyj_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
lyj_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
lyj00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
FKV23_02610 (thrA)
00270 Cysteine and methionine metabolism
FKV23_02610 (thrA)
00300 Lysine biosynthesis
FKV23_02610 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
FKV23_02610 (thrA)
Enzymes [BR:
lyj01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
FKV23_02610 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
FKV23_02610 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
ACT_7
NAD_binding_3
ACT
Motif
Other DBs
NCBI-ProteinID:
QDH69118
UniProt:
A0A514BNZ9
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Position
complement(594110..596650)
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AA seq
846 aa
AA seq
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MSSPANPALSIPSEAEPCPARPRRHAHKFGGSSLADAERQRTAATLVDDGDGSPAFDSHV
VVVSAMQGVTDALIALADAAHAGQDWAPDWSALKQRHRIAAEALAAGDTVLREAIDGDFG
ELHARLSATNSDAGDVAWIHGLGEVLSSRLQHAALGGEAAGWARLDAREVLVVHPGELGV
AVDWEESRARLQRWREAHPQPNVVVTGFVASDNQSRPTTLGRNGSDHSGAIFAVLFDADE
LTIWTDVDGVLSADPRLVPDAVCLPMLSYAEACELAYFGAKVLHPQTMAPAIQHELPVRI
RNSRNPRAPGTLISAVSRGPNGAHGAPVKGLSLIEGLALLELSGAGLIGVPGTAERMFAA
LRQAGVSVTMISQGSSEHSICCVVSQSQAELAREAVEAAFAEAIGDGQAQGVSVTGGIAV
LAAVGDGMVGTPGVAARLLGGLAQARVNVRAIAQGAGERNISVAIAERDAQRGLRAAHAA
FWLSPQTLSVGLIGPGNVGRTLLEQLAEATPRFAAGALHGQNLDLRLRAVANSRTMQLHP
KALDPATAVEALQGGEALDLDRFTAHVRAEHLPHAMIVDCSGSDAVAARYAEWLAAGIHV
VTPNKHAGSGSWQRFQAIRKASRDGSAQFRYEATVGAGLPVIRTLRDLIDTGDVLYEIEG
MFSGTLAWLFNKFDGSAPFSELVLEARRLGYTEPDPRDDLSGTDVARKLVILARETGREL
SLADVDVENLVPEVLLGVPLEEFLDRIDELDTPMQARLDAARAEGGQLRYLARLDRDGRA
SVSLSVPPPGHASLYGRLTDNLIQFRTLRYPDNPLVVQGPGAGPEVTAAGVFGDILAIAQ
TLGARA
NT seq
2541 nt
NT seq
+upstream
nt +downstream
nt
atgtcgagtcccgccaatccagctctttccatcccgtccgaggcagagccctgccccgct
cgaccgcgccgccacgcccataagttcggcggcagcagcctcgccgacgccgaacgccag
cgcacggccgccacgctcgtcgacgacggtgacggttcgcctgcattcgactcgcatgtc
gtcgtggtctcggcgatgcaaggcgtcaccgatgcgctgatcgcactggccgatgccgcc
catgctggccaggactgggcgccagactggtccgcgctcaagcagcgccaccggatcgcc
gccgaggccctggctgcgggcgataccgtgctgcgcgaggccatcgacggcgatttcggc
gaactgcatgcccggctgtcggcaacaaacagcgacgcaggcgatgtcgcctggatccac
ggccttggcgaagtgctgtcctcgcgcctgcagcatgccgcgctcggtggcgaagcagcc
ggttgggcccggctggacgcgcgcgaggtgctggtggtgcatccaggcgaactgggcgtg
gcggtggactgggaagaatcgcgcgcacggctgcagcggtggcgcgaggcgcatccacag
ccgaacgtggtcgtcaccggcttcgtcgccagcgacaaccagagccggccgaccaccctc
ggccgcaacggcagtgaccattccggagcgatcttcgcggtgctgttcgacgccgacgag
ctgaccatctggaccgatgtcgatggcgtgctgtcggccgacccgcgactggtgccggac
gcggtgtgcctgccgatgctgtcctacgccgaggcctgcgagctggcctacttcggcgcc
aaggtgctgcacccgcagacgatggcgcctgcgatccagcacgaacttccggtccggatc
cgcaactcgcgcaatccacgagcaccgggcacgctgatcagcgcggtctcgcgcggaccg
aatggggcgcatggcgcgccggtgaagggactcagcctgatcgagggtctcgcgctgctg
gaactgtccggcgccggcctgatcggcgtgcccggaaccgccgaacgcatgttcgcggcg
ctgcgccaggcaggggtgtcggtgacgatgatctcgcagggctcgtccgagcattcgatc
tgctgcgtggtcagccagtcacaggcggagctggcgcgcgaggcggtcgaggccgccttt
gccgaagcgatcggagacggccaggcgcagggcgtcagcgtgaccggcggtatcgcggtg
ctggccgcggtcggcgacggcatggtcggtaccccaggcgtggccgcgcgcctgctcggc
gggctggcgcaggcgcgggtcaacgtgcgcgcgatcgcgcagggcgcgggcgaacgcaac
atctcggtcgcaatcgccgagcgcgacgcgcaacgcggcctgcgcgcggcgcacgcagcg
ttctggctgtcgccgcagacgctgtcggtcggcctgatcggccccgggaacgtcggtcgc
accctgctcgagcaactggccgaggccacgccacgtttcgccgccggtgcgctgcacggg
cagaacctcgacctgcgcctgcgcgcggtcgccaacagccgcacgatgcagctgcatccg
aaggcactggatccggctaccgcggtcgaggcgctgcagggcggcgaggcgctcgacctc
gaccgcttcaccgcccacgtccgcgccgaacatctgccgcacgcgatgatcgtcgactgc
agcggcagcgacgcggtcgccgcacgctacgccgagtggctggccgccggcatccacgtg
gtgaccccgaacaagcacgccggcagcggctcgtggcaacgcttccaggccatccgcaag
gccagccgcgacggcagcgcgcagttccgctacgaagccacggtcggcgccggcctgccg
gtgatccgcacgctgcgcgacctgatcgatactggcgacgtgctgtacgagatcgagggc
atgttctccggcaccctggcctggctgttcaacaagttcgacggcagtgctccgttttcc
gagctggtactggaagcacgccggctcggctacacagagcccgatccacgcgacgacctg
tccggcaccgacgtggcgcgcaagctggtgattctcgcccgtgaaaccgggcgcgaattg
tcgctggccgatgtcgatgtcgagaacctggtaccggaggtgttgctgggtgtcccgctc
gaggaattcctcgaccgcatcgatgagctcgacacgccgatgcaggcgcgactcgacgcc
gccagggccgaaggcggccaactgcgctatctcgcccggcttgaccgcgacggccgtgcc
agcgtgtcgctgtcggtaccgccgcccggccacgccagcctgtacggccgcctgaccgac
aacctgatccagttccgcaccctgcgctatccggacaatccactggtcgtacagggcccc
ggcgccgggccggaagtcaccgccgccggcgtgttcggcgacatcctcgcgattgcacag
acgctgggggcgcgggcatga
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