Mycobacteroides abscessus ATCC 19977: MAB_0337c
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Entry
MAB_0337c CDS
T00657
Name
(GenBank) Probable 2-isopropylmalate synthase (LeuA)
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mab
Mycobacteroides abscessus ATCC 19977
Pathway
mab00290
Valine, leucine and isoleucine biosynthesis
mab00620
Pyruvate metabolism
mab01100
Metabolic pathways
mab01110
Biosynthesis of secondary metabolites
mab01210
2-Oxocarboxylic acid metabolism
mab01230
Biosynthesis of amino acids
Module
mab_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mab00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
MAB_0337c
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MAB_0337c
Enzymes [BR:
mab01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
MAB_0337c
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Sigma_reg_N
Motif
Other DBs
NCBI-ProteinID:
CAM60436
UniProt:
B1MFN6
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All DBs
Position
complement(334320..336143)
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AA seq
607 aa
AA seq
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MTSFSSDEFNYTPRSVVTPNGPIPADQPAWNTQKNSSMPVHRYRSFTDEVEKIELPDRTW
PDKVITRAPQWGAVDLRDGNQALIDPMSPARKRRMFDLQIRMGFKEIEVGFPSASQTDFD
FIRELITENAIPDDVTIQVLTQCRPELIERTFLACEGASKVIVHFYNSTSILQRRVVFRE
DKDAIKKIATDGAHKCVEEAAKYPDTHWRFQYSPESYTGTELQYALEVCNAVGDIVEPTP
DNPIIFNLPSTVEMTTPNVYADSIEWMSRNLARRDSVILSLHPHNDRGTAVAAAELGFQA
GADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRHTVEYCNQLKVPER
HPYGGDLVYTAFSGSHQDAINKGLDQMKRDADEADSDVDDILWQVPYLPIDPKDVGRNYE
AVIRVNSQSGKGGVAYIMKSDHGLVLPRRLQIEFAQSIQRITDGEGGEVNPKEIWDVFAE
EYLAPITPLERIRQKVTASEEDGGTDSIAAVVKIDGKETEVNGTGNGPLAAFVDALSTVG
YTVNVLDYSEHALSAGDDAQAAAYVEATVVSPGGGEAQTVWGVGIAPSITTASLRAVVSA
VNRAARA
NT seq
1824 nt
NT seq
+upstream
nt +downstream
nt
atgactagcttctcctcagacgagttcaactacacccctcgcagcgtcgttaccccgaat
ggacccattcccgccgatcagccggcatggaacacccagaagaacagctcgatgccggta
caccggtaccgctctttcaccgacgaggtcgaaaagatcgagctgccggaccgcacctgg
cccgacaaggtaattacccgtgcaccgcagtggggcgccgtcgacctgcgcgacggcaac
caggccttgatcgatccgatgagtcccgcccgcaagcgccggatgttcgatctgcagatc
cggatgggcttcaaggagatcgaagtcggtttcccgtcggccagccagaccgatttcgat
ttcatccgcgagctgatcaccgagaacgcgattcccgacgatgtcaccatccaggtgctg
acccagtgccgtccggagctgatcgagcggacgttcctggcgtgtgagggcgcgtccaag
gtgatcgtgcacttttacaactcgacctcgatcctgcagcggcgggtcgtgttccgcgaa
gacaaggacgcgatcaagaagatcgccaccgacggcgcacacaaatgcgtcgaagaagcc
gcgaaatatcccgacacccattggcgtttccagtactcccccgagtcgtacaccgggacc
gagctgcagtacgcgctggaggtgtgtaatgccgtcggcgatatcgtcgagccgacgccg
gacaatccgatcatcttcaacctgccgtcgacggtggagatgaccacccccaacgtgtac
gccgactccatcgagtggatgagccgcaatctggcccgccgcgattcggtgatcctgagc
ctgcatccgcataacgaccgcggaacagcggtcgccgcagcggagttgggcttccaggcg
ggcgcggaccgcatcgagggctgtctgttcggcaacggtgagcgcaccggaaacgtctgc
ctggtaacgctgggactgaacctgttcagtcgaggcgtcgacccacagatcgacttctcg
aacatcgatgagatccggcacacggtcgagtactgcaaccagctgaaggtgcccgagcgc
cacccgtacggtggcgatctggtctacaccgccttctccggcagtcaccaggacgccatc
aataaaggcctggatcagatgaaacgcgatgcagacgaagcagattcggatgtcgatgac
atcctgtggcaggtgccgtatctgcccatcgatcccaaggatgtcgggcgcaactacgag
gccgtgatccgcgtcaactcgcagtcgggcaagggtggtgtcgcctacatcatgaagtcc
gatcatggactggtgctgccgcgccgtctgcagatcgagttcgcacagtcgatccagcgc
atcaccgacggtgagggcggcgaggtgaaccccaaggagatctgggatgtcttcgccgag
gagtacctggcaccaatcaccccgctggagcgcattcgccagaaggtgaccgcctccgaa
gaggacggtggcacggattccattgccgccgtggtgaagatcgacggcaaggaaaccgag
gtcaacggcacgggtaacggtccgttggcagctttcgtggacgccctgtccaccgtgggc
tacaccgtcaacgtgttggactactccgagcacgcgctgagcgcaggcgacgacgcgcag
gccgccgcctacgtggaggccacggttgtcagccccggcggcggtgaggcgcagaccgtc
tggggtgtcggcatcgcgccgtcgatcaccaccgcctcgctgcgggcagtggtgtcggcg
gtcaaccgtgctgctcgcgcctag
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