Methanosarcina acetivorans: MA_1802
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Entry
MA_1802 CDS
T00080
Symbol
ilvD
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
mac
Methanosarcina acetivorans
Pathway
mac00290
Valine, leucine and isoleucine biosynthesis
mac00770
Pantothenate and CoA biosynthesis
mac01100
Metabolic pathways
mac01110
Biosynthesis of secondary metabolites
mac01210
2-Oxocarboxylic acid metabolism
mac01230
Biosynthesis of amino acids
Module
mac_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
mac00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MA_1802 (ilvD)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
MA_1802 (ilvD)
Enzymes [BR:
mac01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
MA_1802 (ilvD)
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Gene cluster
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Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
Motif
Other DBs
NCBI-ProteinID:
AAM05208
UniProt:
Q8TPV2
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Position
2214810..2216471
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AA seq
553 aa
AA seq
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MRSAIIKEGPERAANRSLLKATGVTDSEMKKPFIAVVNSWNEIVPGHIHLDKLAEAVKAG
IRNAGGVPFEFHTIGVCDGLAMGHEGMKYSLPSREVIEDTIELMVRAHQFDGMVLIPTCD
KIVPGHLMAAGRLDIPAIVVTGGPMLPGYVDDKYTDLISVFEGVGAYSAGKLSEAELKRL
ENLSCAGAGSCAGMFTANTMACMTEALGLSLPGCATAHAVDAKKVRIAKESGERIVALVK
ENLTPRKIVTQKSFENAIMVDMAVGGSTNTTLHLPALAHEFGLELPLKTFDELSRTTPHL
ISLRPGGPNFMLHFDRAGGVEAVVQRLASKLHLDQLTVNGKTIGENLDELEIVNPKLNAE
IITTLENPIHAEGGIAVLKGSLAPDGSVVKQAAVDPKMRVHTGPAKVYDCEEDAMKSILA
GDVKPGDIVVIRYEGPKGGPGMREMLAATAAIGGMGLLESVALITDGRFSGGTRGPCIGH
VSPEASEGGPIGLVKDGDLIEINIPERILNLKVTEEELEKRKAAFVPPKKEVTGYLARYQ
RSVHSANTGGIVD
NT seq
1662 nt
NT seq
+upstream
nt +downstream
nt
atgagaagcgccattattaaagaggggcctgaacgtgctgctaatcgttccctcctgaaa
gcaaccggggttacggattcggaaatgaagaaaccgttcatagcggttgtcaattcctgg
aatgaaatagtccctggccatattcacctggataaacttgctgaagctgttaaagccggg
atcaggaacgcagggggagttccttttgagttccataccataggagtctgcgatgggctt
gcaatggggcatgagggtatgaaatattccctcccgagcagggaggttatagaggacacg
atcgaactgatggtcagagcccaccagtttgacggaatggtccttatccctacctgtgat
aagatcgtgcctggacatctgatggcagcaggcaggcttgatattcctgccattgttgta
accggagggccaatgctcccaggatacgtggatgacaaatacaccgacctcatctcagtc
tttgaaggggtcggagcctatagcgcaggcaaactttccgaagccgaacttaaaaggctt
gaaaacctgtcctgtgcaggagcaggttcctgtgccgggatgtttactgcaaacacaatg
gcctgcatgactgaagccctcgggctgagcctacccggctgtgcaactgcccatgcagtg
gatgcaaaaaaggttcgtattgccaaggaatccggagagcgtattgttgcgcttgtaaaa
gagaacctgaccccgaggaagattgttactcagaagtcctttgaaaatgccataatggtc
gatatggcagtcggaggaagcacaaacaccacattacatcttcctgcccttgcccatgag
ttcgggcttgagctgccccttaagacctttgatgaactgagcaggacaactccccacctg
atttccctccgacccggaggtcccaatttcatgttgcacttcgacagggcaggcggagtc
gaggctgtcgtgcagaggcttgcttcaaaactccaccttgaccagcttacagtcaacggc
aaaactatcggggaaaacctggacgagcttgaaatagttaacccgaagctgaatgcggag
atcattacaaccctcgaaaacccaatccatgccgaaggaggaattgcagtcctcaaaggc
agccttgctccagacggctcagttgtcaaacaggctgcagttgacccgaaaatgcgcgtc
catacgggtcctgcaaaagtgtatgactgtgaagaagacgccatgaagagcatccttgca
ggagatgtaaaacccggagatattgtcgttatccggtacgaaggccccaaaggaggacca
ggcatgcgcgaaatgcttgcagccacagccgcaatcggaggcatgggcctgctcgagtcc
gtggctctgataactgatgggcgcttctccggaggtacccgcgggccatgtatagggcat
gtctctcctgaagccagcgaaggagggccaatagggcttgtaaaagatggggaccttatc
gaaatcaacattcctgaaaggatcctgaatctgaaagtcactgaagaagagctcgaaaag
cgtaaagctgcctttgtgccccctaaaaaagaggtcacgggttaccttgccaggtaccag
cgttccgtccattccgcaaacactggcggaatagtggactga
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