Methanosarcina acetivorans: MA_3748
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Entry
MA_3748 CDS
T00080
Symbol
leuB
Name
(GenBank) 3-isopropylmalate dehydrogenase
KO
K10978
methanogen homoisocitrate dehydrogenase [EC:
1.1.1.87
1.1.1.-]
Organism
mac
Methanosarcina acetivorans
Pathway
mac00300
Lysine biosynthesis
mac00680
Methane metabolism
mac01100
Metabolic pathways
mac01110
Biosynthesis of secondary metabolites
mac01120
Microbial metabolism in diverse environments
mac01210
2-Oxocarboxylic acid metabolism
mac01230
Biosynthesis of amino acids
mac01240
Biosynthesis of cofactors
Module
mac_M00608
2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate
Brite
KEGG Orthology (KO) [BR:
mac00001
]
09100 Metabolism
09102 Energy metabolism
00680 Methane metabolism
MA_3748 (leuB)
09105 Amino acid metabolism
00300 Lysine biosynthesis
MA_3748 (leuB)
Enzymes [BR:
mac01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.87 homoisocitrate dehydrogenase
MA_3748 (leuB)
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-ProteinID:
AAM07101
UniProt:
Q8TJN2
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Position
complement(4623061..4624056)
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AA seq
331 aa
AA seq
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MKLAVIEGDGIGREVIPAAVEVLDAFGLELEKVSLELGYARWERTGSAISEEDIATIKGC
DAVLFGAVTTVPDPSYKSVLLTIRKELDLYANVRPVKPLPGITGVTGRNDFDFIIVRENT
EGLYSGIEEIGPDLSWTKRVVTRKGSERVAEYACKLAKQRKNKLTIVHKSNVLKSDKLFL
DVCRQVASSHGVEYGDMLVDSMAYSLMMRPDKYDVVVTTNIFGDILSDMCAALVGSLGLV
PSANIGEKYAFFEPVHGSAPDIAGKGIANPLAAILCVKMLLEWSGRGKEAALIDRAISYI
LEKKLITPDLGGVSTTAEVGQTVAKYVMQNL
NT seq
996 nt
NT seq
+upstream
nt +downstream
nt
atgaaactcgcggtaatcgaaggtgatgggatcggcagggaagtaattcccgcagctgtt
gaagtcctggacgcgttcggacttgagcttgagaaagtgtctctggaactgggctatgca
agatgggaacggacagggagtgcgatctcggaagaagatatagccacaataaaagggtgc
gacgctgttcttttcggggcggttaccacagtacctgacccgagttacaaaagtgtgctt
ctgacaatccgaaaggaacttgacctctatgccaatgtgaggcccgtaaaacctctcccc
ggcataacgggcgttaccgggagaaatgatttcgattttattattgtcagggaaaatacg
gaaggactctactccgggattgaggaaataggccctgacctttcctggacaaaaagagta
gttacccgaaaaggctctgagagggttgcagaatacgcctgcaagcttgcaaaacagaga
aagaacaaacttaccattgtccacaaatccaacgtcctgaagtccgacaaactcttcctt
gatgtctgccggcaggttgccagctcccatggggtggaatatggcgacatgctggtcgat
tctatggcttatagccttatgatgcgccccgataagtacgatgttgtggttactacaaac
atttttggagatatcctgagcgacatgtgcgcagcccttgtgggaagcctggggcttgtc
ccgagcgccaatataggggagaaatacgcctttttcgagcccgtacacgggagcgctccg
gacatcgcaggaaaaggtattgcaaaccctcttgcggcaatcctctgcgtgaagatgctg
cttgaatggagtggcagggggaaagaagctgctcttattgacagagctatcagttacata
ctggaaaagaagctcatcactcctgacctcgggggcgtcagcaccacagcagaagtcggg
cagacggtagcgaagtatgtaatgcagaatctttaa
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