Mycobacterium tuberculosis variant africanum: MAF_14370
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Entry
MAF_14370 CDS
T01575
Symbol
ribA2
Name
(GenBank) putative riboflavin biosynthesis protein RIBA2 : GTP cyclohydrolase II + 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase)
KO
K14652
3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:
4.1.99.12
3.5.4.25
]
Organism
maf
Mycobacterium tuberculosis variant africanum
Pathway
maf00740
Riboflavin metabolism
maf00790
Folate biosynthesis
maf01100
Metabolic pathways
maf01110
Biosynthesis of secondary metabolites
maf01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
maf00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00740 Riboflavin metabolism
MAF_14370 (ribA2)
00790 Folate biosynthesis
MAF_14370 (ribA2)
Enzymes [BR:
maf01000
]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.25 GTP cyclohydrolase II
MAF_14370 (ribA2)
4. Lyases
4.1 Carbon-carbon lyases
4.1.99 Other carbon-carbon lyases
4.1.99.12 3,4-dihydroxy-2-butanone-4-phosphate synthase
MAF_14370 (ribA2)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
DHBP_synthase
GTP_cyclohydro2
fn3
Motif
Other DBs
NCBI-ProteinID:
CCC26509
LinkDB
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Position
1593679..1594956
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AA seq
425 aa
AA seq
DB search
MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP
LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD
DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE
LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA
LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR
GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT
NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGE
FGGAL
NT seq
1278 nt
NT seq
+upstream
nt +downstream
nt
atgacgaggttggactccgtcgagcgggcggttgccgacattgcggcgggtaaggccgtc
atcgtcatcgacgacgaagaccgggagaacgagggtgacctgatcttcgccgccgagaag
gcaacgccggagatggtggccttcatggtccgctacacctccggatacctgtgcgttccg
ctggacggtgccatctgcgaccggctgggcctgttgcccatgtacgcggtgaaccaggac
aagcacgggacggcatacaccgtcacagtcgatgcacggaatggcattggaactggcatt
tcggcgtccgatcgggctaccaccatgcggttgctggccgatccgaccagtgtggccgac
gatttcacccgccccggtcacgtggtccccttgcgggccaaggatggtggggttctgcgc
cggcccggccacaccgaggccgccgtggacctggcccggatggccgggctgcaacccgcg
ggggcgatttgcgagatcgtcagccaaaaagatgagggctcgatggcgcacaccgatgaa
ttgcgggtgttcgccgatgagcacggtctggcgctgatcaccattgctgacttgatcgaa
tggcggcgcaagcacgagaagcacattgagcgggtcgccgaggcgcggattccgactcgt
catggggagtttcgcgccatcggctacaccagcatctacgaggacgtggaacatgtcgcg
ctggtccgcggcgagatcgccgggcccaacgccgacggtgacgacgtgctggtccgggtg
cattcggagtgcttgaccggcgatgtgtttgggtcacgccgctgcgattgcgggcctcag
ctggacgccgcgctggcgatggtcgcccgtgaggggcgcggcgtggtgctgtacatgcgt
ggccacgagggccgcggcatcggcctgatgcacaaactgcaggcctaccaactgcaggac
gccggtgccgacaccgttgacgccaatctcaagcttggactacctgccgacgcaagggat
tacgggatcggcgcacagatcctggtcgatcttggggtacgttcgatgaggctgctgacc
aacaacccggccaagcgggtgggactggatggatacggattgcacatcatcgagcgcgtg
ccgctgccggtgcgggccaacgcggagaacatccgttacctgatgaccaagcgtgacaaa
ttggggcacgacttggctgggttggacgattttcacgaatccgtgcatctgcccggagaa
ttcggcggtgccttgtga
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