Methylotuvimicrobium alcaliphilum: MEALZ_3312
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Entry
MEALZ_3312 CDS
T01649
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase)
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mah
Methylotuvimicrobium alcaliphilum
Pathway
mah00290
Valine, leucine and isoleucine biosynthesis
mah00620
Pyruvate metabolism
mah01100
Metabolic pathways
mah01110
Biosynthesis of secondary metabolites
mah01210
2-Oxocarboxylic acid metabolism
mah01230
Biosynthesis of amino acids
Module
mah_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mah00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
MEALZ_3312 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MEALZ_3312 (leuA)
Enzymes [BR:
mah01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
MEALZ_3312 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IPMS_D2
Motif
Other DBs
NCBI-ProteinID:
CCE24976
UniProt:
G4STH8
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All DBs
Position
complement(3834594..3836138)
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AA seq
514 aa
AA seq
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MKDKLIIFDTTLRDGEQSPGASMTRDEKVRIAKALERMKVDVIEAGFPAASPGDFEAVEA
VAKAVKNSTVCGLARALEKDIDKAGMALKAAESSRIHTFIATSPIHMQMKLQMQPEQVIE
LAVKAVKRALQYTDNVEFSPEDAGRSEEDFLCRILEAVIDAGATTLNIPDTVGYSVPHQF
GATIGNLIQRIPNSDKAIFSVHCHNDLGLAVANSLAAVMNGARQVECTINGLGERAGNAA
LEEVVMAVRTRQDVFPCDTTLDTTEIMTCSRLISTITGFPVQPNKAIVGANAFAHESGIH
QDGVLKSRETYEIMRAEDVGWAANRMVLGKHSGRNAFKTRMTELGFEFTSEAELNEAFFR
FKQLADKKHEIFDEDLQALISEVSVSAEDEYIKLIALSVCSETGEVPTARVTLRIDNQEM
TGSSNGSGAVDASLKAIESLVNTHAILELYSVNNITNGTDSQGEVTIRLDKAGRIVNGLG
ADTDIVIASAKAYINAVNKLQAPNQRRHPQKGDV
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
atgaaagacaaattaattatttttgatacgactttgcgtgatggcgagcagagtccgggg
gcgtcgatgacgcgcgatgaaaaagtccgaattgcaaaagcgctggaaagaatgaaggtc
gatgtaatcgaagcagggtttcctgccgcgagtccgggcgatttcgaagcggtcgaagcg
gttgcgaaagcggtcaaaaacagcaccgtttgcggtttagcgcgggcattggaaaaagac
atcgataaagcgggtatggctctgaaagccgctgaaagctcgcgcattcatacctttatt
gcaacctcgccgattcatatgcaaatgaaattgcagatgcagccggaacaagtgatcgag
ttggccgttaaagctgtgaaacgcgcactgcaatataccgataacgtcgaattttcgccc
gaggatgcggggcgctccgaagaagattttttgtgccggatattggaggcggtcatcgat
gccggtgcgacgacgctgaacatacccgatacggtcggttacagtgttcctcatcaattc
ggcgcgacaatcggtaacttgattcaacggataccgaattccgataaagcgattttctcg
gtgcattgtcacaacgatttgggcttagctgttgctaattctttagccgcggtgatgaac
ggcgcacgccaggtcgaatgcacgatcaacggactcggcgagcgtgccggcaacgccgcg
ttggaagaggtcgtgatggcggtaagaacgcgccaagatgtttttccgtgcgacacgacg
ctcgatacgacagaaatcatgacttgttcgcgtttgatctcgacgataaccggtttccct
gtgcagccgaacaaagcgatcgtcggagccaatgccttcgcgcatgaatccggcattcat
caggacggcgtgctgaaaagccgcgagacttatgaaatcatgcgcgccgaagatgtcggt
tgggccgctaaccgcatggtgttgggtaaacattccggccgcaatgctttcaagacccgt
atgaccgaactcggtttcgagttcacctcggaagcagaattgaacgaggcattttttcgt
ttcaagcaattagccgataaaaaacacgaaattttcgacgaagatttgcaggcgctgatt
tccgaagtcagtgtcagcgccgaagatgaatacatcaaattgatcgcattgagtgtttgc
tccgaaaccggagaagtgccgacggcgcgggttactttacgcatcgataatcaagaaatg
acaggcagttcgaacggtagcggtgcggtcgacgccagtctgaaagcgattgaaagtcta
gtcaatacacacgccattttggaattgtattcggtcaacaatattaccaacggcaccgat
tcgcaaggggaagttacgatacgcctcgataaggcagggcgcatcgtcaatggcttgggt
gccgataccgacatcgtcatcgcttcagcgaaagcctatatcaatgcggtcaataaattg
caagcgcctaatcagcgccggcatccgcaaaaaggcgatgtttaa
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