Monopterus albus (swamp eel): 109951636 Help Entry 109951636         CDS       T05607                                  Name (RefSeq) ryanodine receptor 3-like   KO K04963   ryanodine receptor 3 Organism malb  Monopterus albus (swamp eel) Pathway malb04020   Calcium signaling pathway malb04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:malb00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     109951636    04020 Calcium signaling pathway     109951636  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:malb04040]     109951636 Ion channels [BR:malb04040]  Voltage-gated cation channels   Ryanodine receptor    109951636 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 Ins145_P3_rec MIR SPRY RIH_assoc Ion_trans EF-hand_7 Motif Other DBs NCBI-GeneID:  109951636 NCBI-ProteinID:  XP_020441896 LinkDB All DBs Position Unknown AA seq 4881 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCVACIQKENRKFCLAAEGLGNRLCYLEPTSEAKYAPP DLCICTFVLEQSLSVRALQEMLAKSGQNSEGAAQSGGHKTLLYGHAILLRHSFSSMYLAC LKTSRSQTDKLSFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYL HLSISNGNIQVDASFMQTLWNVHPICSGSNIEEGYLLGGHVMRLFHGHDEVVTIPGSGQS EEQHRIVNYEAGKASAKARSLWRLEPLRISWSGSHIRWGQPFRLRHLTTGHYLALTDDKG LVLQDRERSDTIATAFCFRASKEKLEQSPKRDIEGMGVAEIKYGDSLCFIMHVATGLWLS YQAPDVKSARLGPLKRRACLHSEGHMDDGLTLQRCQHEESRAARIIRNTTLLFNRFIRDL DCLSVKNRALVALPVDEVLQTLNDLITYFQLPDAELEHEEQQIKLRSLKNRQNLFKQEGM LTLVSNCIDRLNVYNSAAHFGECAGLEAGVAWKDILNLLYELLAALIRGNRNNCTQFSNN LDWLVSKLERLESSSGILEVLHCILIESPEALNIIQRGHIKSIISLLYKHGRNHKILDVL CSLCVCNGVAVRTNQNLICDHLLPKRDLLLQTQLVNDVQSMRPNIFLGVSEGSAQYKKWY YELMIDQVDHFVTSEPSHLRVGWANTKGYAPYPGGGEGWGGNGVGDDLFSFGFDGLHLWS GRIPRAVASMNQHILTSEDVVSCCLDLGAPSISFRINGQPVQGMFENFNTDGLFFPVVSF SAGVKVRFLLGGRHGDFKFLPPSNYAPCYEALLPKEKMKVEPVKEYKRDVDGVRDLLGTT QFMSQASFIPTPVETSQTVMPLHLEKVRDKLAENIHELWGMNKIELGWSYGKIRDDNKRQ HPCLVDFCKLPETEKNYNLQMSTETLKTLLALGCCVVHTNPNAEDSLKKLKLPKNYMMCN GYKPSPLDLSDVKLTPGQEMLVDKLAENAHNIWAKDRIKQGWTYGIQQDLRSKRNPRLVP YVLLDERTKKSNRDSLREAIRTLIGYGYNIEPSDQEGVGQVVERLSIDKIRFFRVEKTYA VKTGRWYFEFEAVTGGDMRVGWARPGCKPDVELGTDELAFVFDGYRGHCLNMGGCLFGRC WHTGDVVGCMINMEDKSMIFTLNGEILITTKGSELCFTDFETRDGFIPVCSLGLSQVGRM NLGKDASTFKYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPTFVNVPKDHNHIAVTRIDG TIDSPPCLKVTHKTFGTQNSNADMVFCRLSMPVEFHSHFKLTPVADMNGVHEEDTLKVKH RYPLRSVRHSEESRRLDYSSITTYYHSVRVFAGQDPASVWVGWVTPDYHYYNNNFNLSKN RTVTVTLGDERGRVHESVRRSNCYLVWGGDVTSTAHTSTRSNVDLEIGCLIDLATGLVAF MANGKEISTHYQVEPNTKLFPAVFVRPTSPNLFQFELAKIKNAMPLSSAIFKSEHNNPVP QCPPRLDVQTINAVLWSRMPNTFLKVETSRVSERHGWVVQCVEPLQMLAVHIPEENRCVD IMELSEQEDLRKFHYHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGMLRE GFYNVLISIHLETAKEARLMMKDEFIIPVTAETRSIRLFSDASKKHLLPGAGLSTSLKPR LNFAPPCFISTKREQHLYSPQIPLDALKEKAILMLTEAVQGGGYHIRDPVGGGVEYQFVP ILKLISTLLTMGVLGSEDVHKILLLIDPNVFKDTREEGATGAIDKEGLTGAEEKAVEAGE EEAAKEAKQPKKGLLEKRLPEPVKRQMCELLHYFCDCELKHRIEAIVSFSDSFVSKLQHN QKSRYNELMLALNMSAAVTAKKTKEFRSPPQEQINMLLNFSMGEDCPCPTDIQEELYDFH SQLQLHCGIPMEEDEYEQDTSIKGRLVMLVNKIKGQSHKAEEPRKKEQAAPSNLKELISQ TMVSWAQECHIQDPKLVRKMFSLLRRQYDSIGELLQAMRKTYTISAASVRDTINLLASLG QIRSLLSVRMGKEEEKLMIDGLSDIMNNKVFYQHPNLMRILGMHETVMEVMVNVLGGGKS QEIAFPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLDVAA SSVMDNNGLALALEEPDLDKVVTYLAGCGLQSCTMLVVKGYPDIGWNPIEGERYLCFLRF AVFVNGESVEENSSVVVKLLIRRPECFGPALRGEGGNGLLAAMKEAIKISETPALDLPSS IHGVSDDMSADGDHQEEVVHMGNAIMSFYSALIDLLGRCAPEMHLISKGKGEALRIRAIL RSLVPTEDLVGIISIPLKMPVINKDGSVTEPDMSASFCPDHKAPMVLFLDRVYGIEDQSF MLHLLEVGFLPDLRAATSLDTEGLCTTETALAMNRYIGSAMLPLLTRCAPLFAGTEHYAT LIDSTLHTIYRLSKGRSLTKAQRDAIEECLLAICKYLRPSMLQQLVRRLVFDVPLLSDYC KMPLRLLTNHYEQNWKYYCLLSGWGSYGTASEDELLLTKKIFWGVFDSLSQKKYEAELFK MAMPCLSAIAGALPPDYVDASISTTVEKPVSVDAQGNFDPKPINTANISLPEKLEHFANK YTEHSHEKWFFFLFKFVLLGWKYGDCVDEKVKTHPQLRTYKALTEKEKEIYRWPIRESLK SMLAMGWSIDRTKDGESMSQQRENEKMRKISQTSQANGFNPSPIDTSNVVLSRELQGMVE VVAENYHNIWAKKKKSDLGSRGGGTHPLLVPYDTLTAREKAHVREKAQDLFRFLQINGYS ITRGLKDLEQDSSSLEKRFAYSFLKKLLKYVDSAQEFITHLESMAASGKTDRSPHEQEIK FFAKVLLPLIDQYFKNHSLYFLSSPNKNLSSSGYASNKEKEMVTSLFCKLAALVRHRISL FGSDSTTMVSCLHILAHTLDTRTVMKSGSELVRVGLRTFFENAAEDLEKTFENLKLGKFT HSRSQMKGVSQNINYTTAALLPILTALFEHITEHHFGVDLLLDDVQVSCYRILTSLYALG TGKNIYVERQLPALGQCLATLAGAMPVAFLEPRLNTYNPCSVFNTKSARERAILGIPDSV EQMCPGMLRLDGLMKDINDMAESGARYTEMPHVIEVVLPMLCNYLSYWWERGPENQPASG GSICCTTVTSEHLSVILGNILKILNNNLGIDEASWMKRIAVYVQPIISKARADLLKSHFL PTLVKLKKKTAKVVVEEELLKADSKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNN RSRWLKEPDADSSELFRMVAEIFILWCKSHNFKREEQNFVVQNEINNLSFLTGDNKTKMS KSGGQDQERKHKKRRGEFYSIQTSLIVAALKKMLPIGLNMCTPGDQEIISLAKTRYLLKD TDDEVKDHIRQNLHLREKSEDPAVRWQLNLYKDIVMRSEGPPDPEMVVDRIQRISAAVFN LDQVEQPLRSKKCVWQKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLLAYQRIWIETE EYSFEEKLVQDLAKTQPKMEEEEEEEVRKQPDPLHQLILHFSHNALIERNSLEEDPLYIA YADMMAKSCAEGEDEEGKDKTFEEKEMEKQKLLYQQARLHDRGAAEMVLQMISASKGQLG AMVTFTLKLGISILNGGNILVQQKMLEYLKEKRDVGFFKSLSGLMMSCSVLDLNAFERQN KAEGLGMVTEEGSINVSERGSKVLQNDEFTKDLFRFLQLLCEGHNNDFQNFLRTQTGNTT TVNIIISTVDYLLRLQESISDFYWYYSGKDVIDDAGQRNFSKALAVAKQVFNSLTEYIQG PCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELLDLQKDMIVMMLSLL EGNVVNGTIGKQMVDTLVESSSNVEMILKFFDLFLKLKDLTTSDSFKEYDSESKGVISKK DFQKSMENQKQYSQSEIEFLLSCAEADENDMFSYRQFVERFHEPAKDIGFNVAVLLTNLS EHMPHDARLSTFLNLAESVLSYFEPYLGRIEIMGGAKRIERVYFDISQSSRTQWEKPQVK ESKRQFIFDVVNEGGESEKMELFVNFCEDTIFEMQLASQISEQDPVERPEEDEDDKQCVL ENQEEEAESVTLESSSAFTIACISMKKSLCHLRQLLTIKSMRRQYRKFRKMSVKEMVRGF FSFFWMIITGLFYFVYSLVWGFFHILWTTMFGGGLVEGAKNMKVTDILGNMPDPTQFGIH GDVLETEKMEANEASALAEMDQMAQRDAAEADLMAELLNIQPKKEGKHGTEPGLGDVSEV VVGDAPSIASAVRQKKAQMAAKKRAANGDYKSDSEKADSEDGEKKDRDKAKDEAPPEPSV EKKKAPKKRLGQKRDPPEAFTASFLAGLEIYQTKILNYLARNFYNLRFLALFVAFAINFI LLFYKVTGDYSDDEDPWNGEGRVGEDEDEGAFEYFILQESTGYMAPTLRCLAILHTIISF LCVVGYYYLKVPLVVFKREKEIARKLEFAGLYITEQPSDDDIKGQWDRLVINTPSFPSNY WDKFVKRKVIKKYRDLYGAERIAELLGLDKSALDFNPTEESVTKEASLVSWLSSTDTKYH VWKMGVVFTDNSFLYLVWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQ LVLTVGLLAVVVYLYTVVAFNFFRKFYNKSTDDDEPDMKCDDMMTCYLFHMYVGVRAGGG IGDEIEDPAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMET KCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLVNKDETEHTGQESYVWKMYQE RCWDFFPAGDCFRKQYEDQLG NT seq 14646 nt NT seq  +upstreamnt  +downstreamnt atggctgaaggtggagaaggagaggatgagattcagttcctcagaactgatgatgaagtg gtgctccagtgcgtggcctgtatccagaaggagaatcgtaagttctgcctggctgctgag gggctgggcaaccggctgtgttacctggagcccacatctgaagcaaagtatgctcctcca gacctgtgcatctgcacctttgtgctggagcagtctctgtcagtgcgggccctgcaggag atgctggctaagagtggacagaacagtgaaggggcagcacagagtggtggacataagacc cttctatatggacatgccatccttctgaggcattctttcagctcaatgtacctggcctgt ttgaagacttcaaggtcgcagacagataagctgtcctttgatgtgggcttgcaggaggac tcaacaggtgaggcttgttggtggactatccaccccgcctcgaaacaaagatcggaagga gaaaaagtgcgcattggtgacgacctaatcctcgtcagtgtgtcctcggagcgatacctc cacttatccatctccaatggtaacatccaggtggatgcttccttcatgcaaactctatgg aacgtccatcccatctgctctggtagcaacatagaagaaggctacttgctgggtggtcat gtgatgcggctgttccatggacatgacgaggtagtgaccatcccaggatcaggccagagt gaagagcagcacaggatagtaaattatgaggcgggtaaagccagtgccaaggcgaggtcc ttgtggagactggagccactccgaatcagctggagcgggagccacatccgctggggccag ccttttcgactgcgacacctaaccacaggtcactacctggctttgactgatgataagggg ctggtgctgcaggaccgggaaaggtctgacaccattgccacagccttctgcttcagagcc tctaaggagaagctggagcagagccccaagcgggacattgagggcatgggggtggctgag attaaatacggggactcactctgcttcatcatgcatgtggccacgggactctggctctcc taccaggcacctgatgtcaaatctgcccgtttgggtcccctcaagagacgagcatgccta cattctgaaggtcacatggatgatgggttgaccctccagcgctgtcaacatgaagagtct cgcgctgcacgcatcatccgcaacaccacactactctttaaccgatttataagagacctg gattgtctgagtgtcaagaacagagcgctggttgcactgcctgttgatgaggtgctccaa acgctcaatgatctcatcacctatttccagctccctgatgctgagctggagcatgaagaa cagcagatcaagctgcgctcactcaagaaccggcagaacctcttcaagcaggaaggaatg ctgactctggtgtccaactgtatcgaccgtttgaacgtctacaacagtgcagcccacttt ggggagtgtgctggattggaggccggagtggcctggaaagatattctcaacctgctgtat gagctgctggcggcattaattcgagggaacaggaacaactgcacccagttctccaacaac ttggactggctggtcagcaagctggaaagactggagtcttcttcaggtatcctggaagtt ctgcactgcattctgattgagagccccgaggccctcaacatcatccaaaggggacacatc aagtccatcatatcactgctctacaagcatggacgtaaccacaagattctggatgtgctc tgctcgctgtgtgtgtgtaacggcgtagctgtgcgaactaatcagaaccttatctgtgat cacttactgcccaagagagatctgctgctgcaaacgcagctggtcaatgatgtccagagt atgagaccgaacatcttcttgggggtgagcgagggctcagctcagtataagaagtggtac tatgagctgatgatcgaccaggtggaccactttgtgaccagcgagccctcacacctgaga gtgggctgggccaacactaaaggctatgctccctaccctggaggaggagagggctggggg ggaaacggagttggagatgacctcttttcatttggttttgatggactccacctctggtca ggtcgtattccacgggcagttgcatccatgaaccagcacatactgacctcagaggatgtg gtgagctgttgtctggaccttggagcacccagcatctcttttaggataaacggacagccc gtccagggcatgtttgaaaatttcaacacagacggcctcttcttccctgtcgtcagcttc tctgcaggggtcaaggttcgtttcctgttgggtggtcgacatggtgactttaagtttcta cctccatcgaattatgctccatgttatgaggctctgctgccaaaagagaaaatgaaggtg gagccagtgaaagagtacaagagagatgtagacggagtcagagatctgttgggcactact cagttcatgtcgcaggcctccttcatccccacacctgtggaaaccagccagactgtcatg cctcttcatctggagaaggttcgggacaagctggctgagaacatccatgaactatggggc atgaataagattgagctgggctggtcatacggcaagataagggatgataataagcgccaa catccctgccttgtggatttctgcaagctgccagaaactgaaaagaactacaacctgcag atgtcaacagaaactctcaagaccctgctggcattgggctgctgtgtagttcacacaaat ccaaatgctgaggactccctcaaaaagttaaaactccctaaaaactacatgatgtgcaat ggttataagccatctcctctggacctgtcagatgtaaaactaaccccaggtcaggagatg ctggttgacaaactggcagagaatgcacacaacatttgggcaaaggaccgcattaaacag ggctggacttacggcatacagcaggacctgaggagtaaacgtaaccctcgcctggttccc tatgttctgctggatgagcggaccaagaagtccaacagggacagcctgcgggaggctatc cgtactctgattggatatggttacaacattgagccctcagaccaggaaggtgtaggacaa gtggttgagcggctcagcattgacaagatccgcttcttcagagtagagaagacatatgct gtaaagaccggaagatggtactttgaatttgaggctgtgacgggaggagacatgagagtg ggctgggccagacctggatgtaaaccagacgtggagcttggcacagatgaacttgcattt gtctttgacggatacagaggccactgtctgaacatgggtggctgtttgtttggtcgctgc tggcacactggggacgtggtgggttgtatgatcaacatggaggacaagtccatgatcttc acgcttaatggagagattctcatcactaccaagggctctgaactctgcttcactgacttt gaaactcgcgatgggttcattccagtatgtagtcttggcttgtctcaggtgggccgcatg aatctgggaaaagatgctagcaccttcaagtactacaccatgtgtggccttcaggaaggt tttgaaccctttgctgtcaacatgaacagagaggtcaccatgtggttcagcaagcgtctg cctacttttgtcaatgtgccaaaggaccacaaccacatagcagtaactaggatcgatggc accattgatagcccaccatgccttaaagtgacccacaagacgtttggcacccagaacagt aacgccgacatggtgttttgccgtctcagcatgccagtagagttccactctcactttaag ctcactcctgttgcggacatgaatggagtacatgaggaagatacccttaaagtcaaacac agatatccactgagatctgtgaggcacagtgaggaaagtagacgactggactacagcagc atcactacgtattatcactcagtgagggtctttgctggtcaagaccctgccagtgtgtgg gttggatgggttacccccgactaccattactataacaacaatttcaacctgagcaagaac cgaacagtgactgtgaccctgggtgacgagcgaggacgagtccatgagagtgtgaggagg agtaactgctacctggtatggggtggtgatgtgaccagcactgctcacacctccactcgc agcaatgtggacctggagattggctgtctaatagacttggccaccggcctggtggcattc atggccaacggcaaagagatatcaacacactaccaggtggaaccaaacaccaaactcttt cctgccgtgtttgtgcgacccaccagcccaaacctcttccagttcgagttggctaaaata aagaatgccatgcccctctcatcagccatctttaagagtgaacacaacaacccagtaccc cagtgtccaccacgactagacgtccagaccatcaatgcagtgctttggagccgcatgcct aacaccttcctcaaggttgaaacgtccagggtcagtgagagacacggctgggtggtccag tgtgtggagccactgcagatgttagctgtacatatacctgaggagaacaggtgtgtcgac atcatggagctgtctgagcaggaggatttgaggaagttccactaccacaccctgaagctc tactgtgccctgtgtgctctgggtaacacccgtgtggcccatgccctgtgcagccacctg gaccaatcccagctcttgtacactattgacaatcagtacctgtcaggcatgttacgtgag ggcttctacaatgtcctgatcagcatccacctggaaactgccaaagaggcacgactcatg atgaaagacgagttcatcatccctgtcacggctgagacgcgctccatccgtctcttctct gatgcttccaaaaagcacctcctacctggggcgggacttagcacctcactcaaaccacgt ctcaactttgctccaccctgtttcatcagcaccaaaagggagcaacatctgtatagtccc caaatcccactggatgcactgaaggaaaaagcaattttgatgttgacagaggctgttcag ggtggaggatatcatattcgagatcctgtaggaggaggtgtggagtatcagtttgtacca atcctgaaactcattagcaccttgctgacaatgggtgttttaggcagtgaggacgttcat aagatcttattgctcattgacccaaatgtgtttaaagatacacgagaggagggagccact ggggccatagacaaagaaggacttacaggagcggaggagaaggctgtggaagctggagaa gaggaggcagccaaagaggctaaacagcccaagaaaggcctgctggagaagaggctgcct gagccagttaaacgacagatgtgtgagctgcttcactatttctgcgactgtgagctgaag caccgaattgaggccatcgtgtcattttctgacagctttgtctcaaagctgcagcacaac cagaagtcccgctacaatgagctgatgctggccctcaacatgtctgctgctgttactgca aagaagaccaaagaatttagatcacctcctcaagaacagatcaacatgctgttgaacttc agtatgggtgaggactgtccatgtccaacagacatccaggaggaactctatgattttcac agccagctgcaactccattgtggaatccctatggaggaagacgaatatgagcaagataca tcgattaaaggtcgcctcgtaatgctggtgaacaagatcaaaggccagtctcacaaagca gaggagcccaggaagaaggagcaagcagcaccatctaatctgaaggagctgatttctcag acgatggtcagttgggcccaggagtgtcacatccaagacccaaagctcgtccgcaaaatg ttcagtctactgaggaggcagtatgacagcattggggagctgctccaagccatgaggaag acttacaccattagtgctgcctcggtgcgggacactatcaacctcctggcctccctgggt cagatcagatctctgctctctgtccgtatggggaaagaagaggagaagctcatgatcgat ggactaagcgatatcatgaacaacaaggtgttctaccagcacccgaacctaatgagaata cttggaatgcacgagaccgtcatggaagtcatggtcaatgtgctcggaggaggcaaatcc caggagatcgctttcccaaagatggtggccagctgttgtcgcttcctgtgctacttctgc cggatcagccgtcagaaccagaaagccatgttcgaccacctgagctacctgctggagaac agcagcgtgggtcttgcttcaccagctatgaggggctccactcctctagatgttgctgcc tcctcagtgatggacaacaacggcctggctctggcactggaggaacctgatctggacaag gtggtcacctaccttgcaggctgtggtctccagagttgtacaatgctagtggttaaaggt tatccagacattggctggaaccccattgagggagagcgctacctttgctttttgcggttt gctgtcttcgtcaatggtgagagtgtggaggagaactctagtgttgtggtcaagctgctt atccgtcgcccagagtgttttggacctgccctaaggggagagggagggaacggcctgctg gctgccatgaaggaagcaattaagatctctgagactccagctttggacctgccaagctcc atccacggagtcagcgatgacatgtctgctgatggtgatcaccaagaggaggtggtacac atgggcaatgccatcatgtccttctactctgcacttattgacctgttgggacgttgtgcc cctgagatgcatctcatcagcaagggaaaaggtgaagctttgcgtattcgtgccatcctg cgttctctggtgcccactgaggaccttgtgggaattatcagcataccactcaaaatgccc gtcatcaacaaagatggttcagtgacagagccggacatgtcagccagtttttgtccagac cacaaggcccccatggtgttgtttttagacagggtttatggtattgaggaccaaagcttt atgcttcacctgcttgaagtgggcttccttcctgacctgagggctgctacctctctggat acggagggtttgtgtaccaccgagacagccctagccatgaaccgctacatcggctcagcc atgctccctctcctcacccgctgtgccccactctttgctggcactgagcactacgccacc cttattgactccactcttcacaccatctaccgtctttctaagggccgttcactcaccaag gctcagagagatgccattgaagagtgcctgctggctatctgcaagtaccttcggccctct atgctgcagcagcttgtgcgtcgccttgtctttgatgtgcccttgctgtctgattactgc aagatgcctctcaggctgctaaccaatcactatgagcagaactggaagtactactgtctc ctgtcaggctggggcagctatggcacagcatctgaggatgaactactccttaccaagaaa atcttctggggagtgtttgattctctgtcccagaagaaatatgaagcagagctgttcaag atggccatgccttgcctcagtgccatagctggagccttgccgccagactatgtggatgcc tccattagtaccactgtggaaaagcctgtttctgtagatgctcagggcaactttgacccc aaacccattaatactgctaacatttctcttccagagaagcttgagcactttgccaacaaa tacaccgagcattcccatgagaaatggtttttttttctttttaagtttgtgttgttgggg tggaaatatggagactgtgtggatgagaaggtcaagactcacccgcagctcaggacctat aaagccctgacagagaaggagaaggagatttacagatggccaattagagagtccctgaag agtatgctggcaatggggtggagcattgacaggaccaaagatggagagagtatgtctcaa cagagggagaatgagaaaatgcgaaagatatctcagacctcacaggcaaatggtttcaat ccaagcccgatagacacaagcaatgtggttctttccagagaactgcaggggatggtggag gtggtagctgaaaattatcataacatctgggccaagaagaaaaagagcgaccttggaagt agaggtgggggaacacaccctctgttggtgccctatgacaccctgacagccagggagaag gcccatgttcgagagaaggctcaggacctctttcgcttcctgcaaatcaatggctatagc atcacaagaggtctgaaggacttggagcaggattcttcttctttggagaagaggtttgcc tatagttttctcaagaagctgctcaagtatgttgactcagctcaggaattcatcactcac ctggagtccatggctgccagtgggaaaacagacagatcccctcatgaacaagaaatcaag ttttttgccaaagttctcctccctctcattgaccagtacttcaagaaccactctctctac ttcctctcttcccccaataagaacctgagcagcagcggttatgcctccaacaaggagaag gagatggtcaccagcctgttttgtaaactggcagctcttgtcagacataggatttcactc tttgggagtgactccaccaccatggtgagctgtctgcatatcctggcacacactttggac accaggacggtgatgaagtcgggctcagagctggtgcgggtgggcctcaggacattcttt gagaacgccgcagaggatctggagaagacgtttgagaacctgaagctggggaagttcact cactcccgctcgcagatgaagggggtgtcgcagaatatcaactacaccactgctgctctg ctccccatcttaaccgctctgtttgaacacatcactgaacaccactttggagtcgacctg cttttggatgatgttcaagtgtcctgctatcgaattctgaccagcctctatgccctgggc actgggaaaaacatctatgtagaaagacagctgccagctcttggtcagtgtctggccacc ctggctggggccatgcctgtagcctttctggagccacggctcaacacctacaacccctgc tctgtctttaataccaagagtgccagagaacgagccatcctaggcataccagactcagtg gagcagatgtgtcccgggatgctgcggctggatggtctgatgaaggacatcaatgacatg gctgagtctggagcacgatacacagagatgccccatgtgattgaagtggtcctacccatg ctgtgtaactatctgtcctactggtgggagaggggtcctgagaaccagccagccagtggt ggcagtatctgctgcaccaccgtcacctcagagcacctcagtgtcattcttggcaacatc ctcaagatccttaacaacaatctgggcattgatgaggcctcctggatgaagaggattgca gtgtatgtgcagcctatcatcagcaaggcccgtgcagacctgctgaagagccacttcctg cctactctggtgaagctgaagaagaagacggcgaaggttgtagttgaggaggagctgttg aaagctgacagcaagggagacacccaggaagctgagctgcttatcctggatgaatttgct gtactctgcagggacctctacgctttttaccccatgctcatccgctatgtggacaacaac aggtccaggtggctgaaagaaccagatgctgactccagtgagctcttcagaatggttgct gagatatttattctttggtgcaagtcacataatttcaaaagagaagagcagaactttgtt gtccagaatgaaatcaacaatctttcctttttgactggagataataaaaccaagatgtct aaatctggaggacaagaccaggagaggaaacacaagaagagacgtggtgagttctactct attcagacctcactgattgtggctgctctgaagaagatgctgccaatcggactcaacatg tgtaccccaggggaccaggagatcatatctttagccaagacacgctacctcctgaaagac acagatgatgaggtcaaagaccacattcgacagaatctgcatcttcgagaaaaatcagag gacccggcagtgaggtggcagctgaacctatacaaggacatagtgatgaggagcgaaggg cctccagacccagagatggtggtggaccgtatccagaggatctctgctgctgtattcaac ctggaccaggtggagcagccactgagatcaaagaaatgtgtgtggcagaagctgctgtct aagcagaggaaaagagcagttgtagcctgcttccgcatggctccactttataatctacca aggcatcgctctattaacctcttcctcctggcctatcagagaatatggatagaaacagag gagtactcttttgaggagaagctagtgcaggatcttgcaaaaacacagcccaaaatggag gaagaggaagaggaggaggttagaaagcagccagaccctcttcaccagctcattctgcat ttcagccataatgctctgattgagcgcaattctttggaagaggatcccctgtacattgca tatgcagatatgatggcaaagagttgtgctgaaggtgaagatgaggaaggaaaagacaaa acatttgaggaaaaagaaatggagaaacaaaagctgctgtatcaacaagccagacttcat gaccgaggggctgcagagatggtgctgcagatgatcagtgccagcaaaggacaacttggt gctatggtgactttcaccctcaaactgggcatctccattctcaatggtggaaacatactg gtccagcagaaaatgctggaatatctgaaggaaaaaagagatgttggctttttcaaaagt ttatctgggctgatgatgtcttgcagtgtcctggacttgaatgcttttgaaaggcaaaac aaagctgaaggtctggggatggttactgaagaaggctcaatcaacgtgagtgagcggggt tccaaggtactgcagaatgatgagttcacaaaggatctctttaggtttttgcagcttctc tgtgagggccacaacaacgattttcagaacttcctgaggactcagacagggaacacaact acagtcaatatcatcattagtactgtagactatctactaagacttcaggaatctatcagt gacttctactggtactactctggtaaggatgttattgatgacgctggtcagaggaacttc tcaaaagctctggcagtggcaaagcaggtcttcaactctttaactgagtatatacagggt ccgtgtattggcaaccagcagagcctggctcacagcaggctgtgggatgcagtggtgggc ttcctgcatgtttttgccaacatgcagatgaagttatcacaggactccagtcaaatagaa ttattgaaggagctactggacctccagaaggacatgattgtcatgatgctttctctcctt gaaggtaatgttgtcaatggtaccattggcaaacaaatggtggacaccttggtagagtct tctagcaatgtggaaatgatcctcaaattttttgacctgtttctcaagttgaaggactta accacgtcagacagcttcaaggagtacgactcagagagcaaaggggtcatctcaaagaag gatttccagaagtccatggagaaccagaagcagtattcccaatccgagattgagtttctt ctctcatgtgctgaggctgatgagaatgacatgttcagctacaggcagtttgtggagagg tttcatgaaccagccaaggacataggctttaacgtagctgtgttgttgaccaatctctcg gagcatatgcctcatgatgctcgcctctcgactttcctcaacctagccgagagtgttctc agctactttgagccctatctgggccgaattgagataatgggtggagccaagcgtatcgag agagtctactttgacatcagccaatcaagtcgtacccagtgggaaaagccacaggtgaaa gagtcgaagcggcagttcatcttcgatgttgtcaatgaaggtggggagagtgagaagatg gagctgtttgtcaacttctgtgaggacaccatctttgagatgcagctagcttctcaaatt tcagagcaagacccagtagagcgcccggaggaggacgaagatgacaagcagtgtgtactg gagaaccaggaggaagaggcggagagcgtgacattggaatcatcctctgccttcaccatt gcctgcatctcaatgaaaaaaagcctctgccacttgcgccaactgctaactattaagagc atgagacgacagtacagaaaattcaggaagatgagtgtgaaggagatggtgcgagggttc ttctccttcttttggatgatcatcacgggacttttctattttgtttacagcttagtttgg ggtttcttccatattttgtggaccactatgtttgggggtggcctcgttgaaggggctaag aatatgaaggtgacagacattttgggaaacatgccagaccccactcagtttggcatccat ggagatgtgttagagacggaaaagatggaggcgaatgaagcatcagcattggcggagatg gatcagatggctcagagggatgcagcagaggcagacctgatggctgagttactcaacatt cagcccaagaaggagggaaagcatgggaccgagccaggtttgggggatgtgtctgaggtt gtggtgggggatgctccatctatagccagtgctgtcaggcagaagaaggcacagatggca gcaaagaagagggctgcaaatggagactacaaatctgattcagagaaagcagattcagaa gatggtgagaagaaggaccgtgataaggccaaagatgaagcccctccagagccttcagtg gagaagaagaaagccccaaagaagaggctcggccagaagagagatccaccggaggccttc acagccagcttccttgcaggcttagaaatctaccagaccaagatactgaattacctggcc agaaatttctacaaccttcgtttcttggcactttttgtagcctttgctattaacttcatt ctcctcttctacaaagtaacaggtgattactcagacgatgaagacccctggaatggtgaa ggtagagtcggagaggacgaagatgaaggagcatttgagtacttcatcctgcaggagagc acaggctacatggcgccaacgcttcgctgtctggcaatactacacacgatcatatctttc ctgtgtgtagtgggatactactacttgaaggtgcccctggtagtgttcaagcgggagaag gagatagcaagaaagttggagtttgcaggcctctatatcacagagcagccttctgatgat gacatcaaaggacagtgggacagactggtcatcaatactccgtctttcccaagcaactac tgggataaatttgtcaaacgcaaagtgatcaaaaagtacagagacctgtacggagcagag aggatagcagagctgctgggattggacaagagtgccttggatttcaacccgacagaggaa agtgtcactaaggaggcttcactggtgtcatggttgagctcgactgatacaaagtaccat gtctggaaaatgggagtggtgtttacagacaattcattcctgtatctggtgtggtacacc accatgtctattctgggccactacaacaacttcttcttcgctgcccatctattggacatt gccatgggcttcaagaccctccgcaccatcctctcctctgtcacacacaacggcaaacag ctggtgttgacagtgggcttgctggcggtcgtggtctatctctacactgtggtggccttc aacttcttcaggaaattctacaacaagagcacggatgacgatgagccagacatgaagtgt gatgacatgatgacatgctacctgttccacatgtatgttggcgtgagagcaggagggggc atcggggatgagattgaggacccggctggggacccctatgagctctaccgtatacttttt gacatcaccttcttcttttttgtcattgtaatccttctagccatcatccagggtttgatc attgatgcttttggagaactgagagaccagcaggaacaagtcaaagaggacatggagacc aaatgtttcatttgtgggatcggtaacgactacttcgacacaacacctcatggctttgaa actcacactttacaagagcacaatctggccaactacctatttttcctgatgtaccttgtc aacaaggatgagactgagcatactggccaggagtcatatgtgtggaagatgtaccaggaa cgatgctgggacttcttcccagccggcgattgtttccgtaaacagtatgaagatcagctt ggatag

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