Microcella alkaliphila: MalAC0309_0953
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Entry
MalAC0309_0953 CDS
T05359
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alan ine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
malk
Microcella alkaliphila
Pathway
malk00300
Lysine biosynthesis
malk00550
Peptidoglycan biosynthesis
malk01100
Metabolic pathways
malk01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
malk00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MalAC0309_0953
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MalAC0309_0953
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MalAC0309_0953
Enzymes [BR:
malk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MalAC0309_0953
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
BAU31817
UniProt:
A0A0U5B7I5
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Position
959751..961304
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AA seq
517 aa
AA seq
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MIDLLTAPATLVAFAAGLLVAVPVAARWLRVAQREHYVPGWTTRMAWLWVTREPVTAALL
VVAIGATFVAVLGGVPPLGDYWALVALLALAFVPLGLPVRGRSAKFAITDRVKRLMVAWI
VVHLLVAVLLAALLGAAGVALTLLVSAPLTDLALAIMAPIEKAGSKKFVVQAQKRLQQVK
PRVVAITGSYGKTSTKNYVAHLVSATFPTVASPASFNNRLGLSRAVNDKLVPGTEIFVAE
MGIFGAGEIRELCGYFPPDIAAITVIGEAHLERMRSTDVIFRAKAEITEKAATVVLPIDD
ERLARHAALCAEQGKTVVTVSTAGADADVVLDAHAGTIRIGRATEPVAVTVSGTGHAVNV
AVAAGIALAAGVPVDTIAGRLGDLPGSAHRAEVQVAPSGARIIDDTYNSNPVGAHRALEG
AQALAAETGGPLVVVTPGMVELGPVQVERNRAFGAAIKEAGGALYAVGRTNRAALVSGFG
DGAVAVATREQAVKAAVEAAGDRGVILYENDLPDHYP
NT seq
1554 nt
NT seq
+upstream
nt +downstream
nt
atgatcgacttgctcaccgcccccgcaaccctcgtggcgttcgcggccgggctgctcgtc
gccgtgcccgtcgcggcgcggtggttgcgcgtcgcgcagcgcgagcactacgtgcccggc
tggaccacgcgcatggcgtggctctgggtgacacgcgagcccgtgacggctgcgctgctc
gtcgtcgcgattggtgccacgttcgtcgccgtgctcggcggggtgccgcctctcggcgac
tactgggcgctcgttgcccttctggcgcttgcgttcgtgccgctcggcctgccggtgcgc
ggccgctcggcaaaattcgcgatcacggatcgcgtgaagcgactcatggtcgcgtggatc
gtcgtgcacctgctcgtggcggtattgctggcagcgctgctgggggcagccggtgttgct
ctcacgctgctcgtcagcgccccgctcaccgacctcgcgctcgcgatcatggcgcccatc
gagaaggccgggtcgaagaagttcgtcgtacaggcgcagaagcggctgcagcaggtgaag
ccgcgcgtcgtcgcgatcaccggctcgtacggcaagacgagtaccaagaactacgttgcg
cacctcgtgagcgcgacattcccgaccgtggcgagtcccgcatccttcaataaccggctg
gggttgtcgagggccgtcaacgacaagctcgttcccggcaccgagattttcgtggccgag
atgggcatcttcggcgcgggcgagattcgtgaactgtgcggctacttcccgcccgacatc
gccgcgatcaccgtcatcggcgaggcgcacctcgagcgcatgcgctcgaccgacgtgatc
ttccgcgcgaaggccgagatcaccgagaaggcggccaccgtggtgctgccgatcgacgac
gagcgccttgcccggcacgcggcgctgtgcgccgagcagggcaagaccgtcgtgacggtg
tcgacggcgggtgccgacgccgacgtcgtcctggatgctcatgccggcaccatcaggatc
ggtcgcgccaccgagccggtcgccgtcaccgtgtcgggtacggggcacgcggtcaacgtc
gccgtggcggccggaatcgcgctggccgccggggttccggtcgacacgatcgcggggcgc
ctcggcgacctgcccggctcggcccaccgcgccgaggtgcaggtggcgccgagcggggcg
cgcatcatcgacgacacgtacaactcgaacccggtcggcgcgcaccgcgcgctcgagggg
gcgcaggcgctcgccgccgagacgggagggccgctcgtggtggtcactccgggcatggtc
gagttgggtccggtgcaggtcgaacgcaatcgggcgttcggcgcggcgatcaaggaggcc
ggcggtgcgctgtacgccgtgggtcgcacgaaccgggccgcgctcgtctcgggattcggc
gacggcgcggtcgcagtcgcgacgcgcgagcaggccgtgaaggccgcggtcgaggctgcc
ggtgaccggggcgttatcctctacgagaacgacctgcccgatcactatccgtga
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