Mycolicibacterium alvei: MALV_03250
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Entry
MALV_03250 CDS
T06961
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
malv
Mycolicibacterium alvei
Pathway
malv00300
Lysine biosynthesis
malv00550
Peptidoglycan biosynthesis
malv01100
Metabolic pathways
malv01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
malv00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MALV_03250 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MALV_03250 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MALV_03250 (murF)
Enzymes [BR:
malv01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MALV_03250 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BBX25200
UniProt:
A0A6N4UK61
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Position
341225..342811
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AA seq
528 aa
AA seq
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MIEMTIARIAEIVGGELADITADEAAATRVTGTVEFDSRAIGTGGLFLALPGARSDGHDF
AARAVAAGAVAVLAARPVGVPAIIVSPDPKGADTASGALEFDTDGSGAAVLAALAKLAAA
VAAELVADGLTIIGVTGSSGKTSTKDLLAAVLDPLGQVIAPPGSFNNELGHPWTVLRATP
ETDYLILEMSARHPGNIAALAAIAPPQIGVVLNVGTAHLGEFGSREAIASTKAELPQAVP
SSGVVILNVDDTAVAAMAGKTEARVVRVSREPGAAVDVWAGPVTLDDLARPRFALHAGGG
EVEVALAVHGDHQVGNALCAAAVALQCGADLDQVATALAGAGPVSRHRMAVGTRADGVTV
INDAYNANPDSMRAGLKALAWMARQGGGDAGGDLHGKRRSWAVLGEMAELGDDAITEHDA
IGRFAVRLDVSRLIVVGTGRTMNAMHHGAVMEGSWGSESTMVDDADAALALLRAELQPGD
VVLVKASNSVGLGALADALVAAGAGSPSPTAGAGSPSPTAGEVGNADR
NT seq
1587 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgagatgaccatcgccaggatcgccgagatcgtcggcggcgagttggccgacatc
actgccgacgaggccgccgcgacccgcgtcaccggcaccgtcgaattcgactcccgggcg
atcggcaccggtgggttgttcctggcgctacccggtgcccggtccgacggccatgacttc
gcggcgagggcggtggcggccggggcggtagccgtgctggccgcgcgcccggtcggggtg
cccgcgatcatcgtttcccccgatccaaagggcgccgacaccgcttctggcgctctggaa
ttcgataccgatgggtccggtgcagcggtgctggccgcgctggccaagttggcagcggcg
gtcgcagccgaactggtcgccgacgggctgacgatcatcggggtgacgggatcctcgggc
aagacctcgaccaaggatctgctggcggcggtgctggatccgctcgggcaggtgatcgcg
ccgccgggctcgttcaacaacgagctggggcatccgtggaccgtgctgcgcgccacgccc
gagaccgactacctgatcctggagatgtcggcccggcatccgggcaatatcgccgccctg
gccgccatcgccccgccgcagatcggggtggtgctcaatgtgggcaccgcacacctcggt
gagttcggctcgcgcgaggccattgccagtaccaaagccgagttgccacaagctgttccg
tcctccggggtggtgatcctcaacgtcgacgacaccgcggtggcggcgatggccggcaaa
accgaggccagggtggtgcgggtctcgcgggagcccggcgcggcggtcgacgtgtgggcc
ggcccggtcaccctcgacgatctggcccgcccgcggttcgcgctgcacgcgggcggtggg
gaagtcgaggtggcgctggcggtgcacggcgatcaccaggtcggcaatgcgttgtgtgcg
gctgcggtcgcgctgcagtgcggcgccgatctggaccaggtggccaccgcgctggcgggc
gcgggcccggtctcgcggcaccggatggcggtcggcacccgcgccgacggtgtgacggtc
atcaacgacgcctacaacgccaacccggattcgatgcgtgccggcctcaaggcgctggcc
tggatggcccgccagggtggtggtgatgccggcggtgacctgcacggaaagcggcgcagc
tgggcggtgttgggcgaaatggccgaactgggcgacgacgcgataaccgagcacgacgcc
atcggacggttcgcggtgcgcttagatgtgtctcggttaatcgtcgtcggaaccgggagg
actatgaacgccatgcaccacggcgcggtgatggagggttcgtggggatctgagtccacg
atggtcgacgacgccgatgccgcgctcgccctgttgcgggctgagctgcagcccggggac
gtggtgctggtgaaggcatccaactcggtggggttgggtgccctggccgacgcgctggtt
gccgcaggagctggatcgccgtctccgacggcaggagctggatcgccgtctccgacggca
ggagaagttgggaacgccgaccgatga
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