Megalobrama amblycephala (Wuchang bream): 125259868
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Entry
125259868 CDS
T08212
Symbol
zgc:158659
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
mamb
Megalobrama amblycephala (Wuchang bream)
Pathway
mamb00562
Inositol phosphate metabolism
mamb01100
Metabolic pathways
mamb04012
ErbB signaling pathway
mamb04068
FoxO signaling pathway
mamb04070
Phosphatidylinositol signaling system
mamb04081
Hormone signaling
mamb04140
Autophagy - animal
mamb04150
mTOR signaling pathway
mamb04210
Apoptosis
mamb04218
Cellular senescence
mamb04370
VEGF signaling pathway
mamb04510
Focal adhesion
mamb04620
Toll-like receptor signaling pathway
mamb04625
C-type lectin receptor signaling pathway
mamb04810
Regulation of actin cytoskeleton
mamb04910
Insulin signaling pathway
mamb04914
Progesterone-mediated oocyte maturation
mamb05100
Bacterial invasion of epithelial cells
mamb05132
Salmonella infection
mamb05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
mamb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
125259868 (zgc:158659)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
125259868 (zgc:158659)
04370 VEGF signaling pathway
125259868 (zgc:158659)
04068 FoxO signaling pathway
125259868 (zgc:158659)
04070 Phosphatidylinositol signaling system
125259868 (zgc:158659)
04150 mTOR signaling pathway
125259868 (zgc:158659)
09133 Signaling molecules and interaction
04081 Hormone signaling
125259868 (zgc:158659)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
125259868 (zgc:158659)
09143 Cell growth and death
04210 Apoptosis
125259868 (zgc:158659)
04218 Cellular senescence
125259868 (zgc:158659)
09144 Cellular community - eukaryotes
04510 Focal adhesion
125259868 (zgc:158659)
09142 Cell motility
04810 Regulation of actin cytoskeleton
125259868 (zgc:158659)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
125259868 (zgc:158659)
04625 C-type lectin receptor signaling pathway
125259868 (zgc:158659)
09152 Endocrine system
04910 Insulin signaling pathway
125259868 (zgc:158659)
04914 Progesterone-mediated oocyte maturation
125259868 (zgc:158659)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
125259868 (zgc:158659)
09171 Infectious disease: bacterial
05132 Salmonella infection
125259868 (zgc:158659)
05100 Bacterial invasion of epithelial cells
125259868 (zgc:158659)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mamb04131
]
125259868 (zgc:158659)
Enzymes [BR:
mamb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
125259868 (zgc:158659)
Membrane trafficking [BR:
mamb04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
125259868 (zgc:158659)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3Ka
PI3_PI4_kinase
PI3K_C2
PI3K_p85B
PI3K_rbd
DUF2321
ABC1
Motif
Other DBs
NCBI-GeneID:
125259868
NCBI-ProteinID:
XP_048033790
LinkDB
All DBs
Position
LG24:complement(218664..234720)
Genome browser
AA seq
1070 aa
AA seq
DB search
MAPRPSSGELWGLHLMPPRILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSADLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKIAHDSLPEQLIAEAIRKKTRSMHLSAQQLR
LCVQEYQGQYILKVCGCDEYFLEKYPLSQYKYIRSCITLARLPHLMLVSKDSLYSQLPAS
GFMAPSYSRRTPQPSPCPGGGDPGSPRSLWAFNTHLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDVPRSARLCLSICSVKGRKGAKEE
HCPLAWGNINLFDYKDTLVSGKVALGLWPVPHGLEDLLNPIGVSGSNPNKETPCVELEFP
WFNQTVVFPDEQQIEEHANWSISRELGYSYCLGLSSRLACDSTISQADAEQLRALCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQIYCLLKDWPLMQPESAL
ELLDCNFPDPMVREFALRCLIQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIKEKNKGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQECSKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKNQQDALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
NT seq
3213 nt
NT seq
+upstream
nt +downstream
nt
atggctcctcggccctcgtcaggagagttatgggggcttcacctgatgcctcctcgtatc
ctggtggactgctgtctgcccaacggcatcctggtcagtctggagtgtctgagggaggct
ccgctgaccagcataaagcagcagctcttcagcgaggcccgcaagtacccgctgtaccac
ctgctgcaggaggagtcctgctacatctttgtgggcgtgacgcaggaggccgagagggag
gagttctatgatgaaacacgccgcctgtgtgaccttcgactctttcaccccatcctaaag
gtcatcgagccgctgggaaacagggaggagaagatactcaacagggagatcggttttgcc
ataggaatgcccatctgtgagttcgagctggtgaaggatccggaggtgcaggacttccgg
cggaacattctgagcgtgtgccgggaggcggtggaggagcgcgagggaggaggcgctcac
acgcaggcgctgtacgtctaccctcccaacgtggagtcctcggccgacctgccgcagcac
atctacagcaaactggacaaaggccgtctgatcgtgaccatctgggtgatcgtgtctccg
tccaactccaagcagaagtacacgctgaagatcgcacacgactctctcccggagcagctg
atcgcggaagccatccgcaagaagacgcgcagcatgcatctgtccgcgcagcagctgcgg
ctgtgtgtgcaggagtatcagggccagtacatcctcaaagtgtgcggctgcgacgagtac
ttcctggagaaatatcctctcagccagtacaagtacatcaggagctgcatcacgctggcc
cgcctgcctcacctgatgctggtcagcaaggacagcctgtacagtcagcttcctgccagc
gggttcatggctccgtcgtacagccggcgcacgcctcagcccagcccctgccccggcgga
ggagaccccggctccccgcgctccctctgggccttcaacacacacctgagagtccggctg
ctgtgcgccacatacgtcaacgtcaacatcagagacatagacaagatctacgtgagaacg
ggaatatatcacggaggagaaccgctgtgtgacaacgtcaacacacagagagtgccctgc
tccaacccgaggtggaacgagtggctgtcgtatgacatctacctgacagatgttcctcgt
tctgctcgtctctgtctgtccatctgctccgtcaagggtcgcaagggtgccaaagaggaa
cactgtccgctggcctggggaaacatcaatctcttcgactataaagacacgctggtcagc
ggtaaggtggctctgggtttgtggccggttcctcacggactggaggatcttctcaaccct
atcggagtgtcgggatcgaacccaaacaaggagacgccgtgcgtggagctggagtttccc
tggtttaaccagacggtggtgtttcccgatgagcagcagatcgaggaacacgccaactgg
agcatctctcgtgagctgggctacagctactgtctggggctgagcagtcgtctggcgtgc
gacagcaccatatcgcaggcggacgccgagcagctgcgagcgctgtgcagtcgagacccg
ctgtatgagctctcagaacaagagaaagacttcctgtggagacatcgccattactgtgtg
aatattccggaaagtcttcccaaactcctgctgtctgtcaaatggaactcgcgggacgaa
gtgtcgcagatctactgtctgctgaaggactggccgctcatgcagcctgaatccgctctg
gagctgctggactgcaacttcccagatccgatggtgcgagagttcgccctgcgctgcctc
atccagggactcaccgacgacaagctcagtcagtacctgctgcagctcgtgcaggtactg
aaatatgagatgtatctagataatccgttagcgcggttcctgatcaagaaagcgttgacc
aatcagaggattggacatttcttcttctggcatctgaagtctgagatgcacaataagacg
gtgtcgcggcggttcgggctgctgttggaggccttctgtcgcgcgtgtggcatgtacctg
aaacacctgaacagacaggtggaggccatggacaagctggtgaacctcacggacacactc
aaacaggagaagaaagacgagacgcagaagactcagatgaagttcctggtggagcacatg
tcccgtccagattacatggaggcgctgcaggggtttgtttctcctctgaaccctgttcac
cagctggggaatctcaggttggaggagtgtcgtatcatgtcttcagccaagcggccgctg
tggttaaactgggagaatccagatatcatgagcgagctgctcttcaccaacaacgagatc
atctttaagaacggagacgatctacggcaagacatgctgacgctgcagattattaaaatc
atggagaatatctggcagaatcaggggctggacctgcgaatgctgccgtacggctgtctg
tccatcggcgactgcgtcggcctcatcgaggtggtgaagaactctcacaccatcatgcag
attcagtgtaaaggaggcctgaagggggcgctgcagttcaacagcaacacactgcaccac
tggatcaaagagaagaacaagggagaggcgtacgacagggccattgatttgttcacgcgc
tcgtgcgctggatactgcgtggccacgttcattctgggcatcggtgacagacacaacagc
aacatcatggtgaaggagaacggacagctgttccatatcgactttggtcacttcctggac
cataaaaagaagaaatttggatacaaacgagagcgagttcctttcgtgctcacacaagac
ttcctcatcgtcatcagcaagggtgtgcaggagtgcagcaagaccaaagagttcgagagg
tttcaggagatgtgttataaggcgtatctggccatccgtcagcacgccagcctcttcatc
aacctcttctctctgctgttgggttgtgggatgccggagctgcagagtttcgatgacatc
gcgtatctgcgcaagacgctggcgctggagaagaaccagcaggacgcgctggagtacttc
accaaacagatgaacgacgcccatcatggaggatggaccaccaagatggactggatattc
cacaccatcagacacatgcccaacgagcactga
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