Mangrovimonas sp. YM274: RBH95_04140
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Entry
RBH95_04140 CDS
T09317
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
mang
Mangrovimonas sp. YM274
Pathway
mang00260
Glycine, serine and threonine metabolism
mang00261
Monobactam biosynthesis
mang00270
Cysteine and methionine metabolism
mang00300
Lysine biosynthesis
mang01100
Metabolic pathways
mang01110
Biosynthesis of secondary metabolites
mang01120
Microbial metabolism in diverse environments
mang01230
Biosynthesis of amino acids
Module
mang_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
mang_M00527
Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
mang00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
RBH95_04140 (thrA)
00270 Cysteine and methionine metabolism
RBH95_04140 (thrA)
00300 Lysine biosynthesis
RBH95_04140 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
RBH95_04140 (thrA)
Enzymes [BR:
mang01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
RBH95_04140 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
RBH95_04140 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
AA_kinase
Homoserine_dh
Abhydrolase_1
NAD_binding_3
ACT_7
ACT
Abhydrolase_6
Motif
Other DBs
NCBI-ProteinID:
WMI69562
UniProt:
A0AA51GMQ7
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All DBs
Position
952233..955628
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AA seq
1131 aa
AA seq
DB search
MKALKFIQLDNFTLESGVELPIQLSYQTFGLPLHEAPIVVVNHALTGNSNVAGSDGWWGS
LIGDDKIIDTKKFTVLAFNIPGNGYDGFLIENYKDFVARDVAKLFLKGLEELNIQQVFAL
IGGSLGGGIAWEMAVLKPKLAEYLIPVATDWKSTDWLIANCQIQEQFLVNSNNPVHDARM
HAMLCYRTPKSFKERFQRSINNELEIFNVESWLLHHGNKLQERFQLSAYKLMNQLLKTID
VTKGREANENILDIISSKIAIVGVDSDLFFTAEENRETQKQLAATHPNVTYHEIHSDHGH
DAFLIEFEQLEKIIEGIFSPDTKHKRMKILKFGGKSLANGEGLTRALEIIEKKVSDGEKI
AVVVSARGNATDELEALLEKASKKEVYKSDFEAFKAYQVEPLPSIDFTSEFSALENIFEG
VALLGDYSEKIKSQVLAFGELLSAKIIAEILKSKGINANATDSRTLIKTEGDFGNSQPIQ
KISKEKVVEHFKKFNGSTVNIVTGFIASNLDGETTTLGRNGSNYSASLLANFLDAEELQN
YTHVNGIYTANPDLVADAQKIRELSFSEANELANFGTSVLHAKTIIPLVEKNINLRILNT
FNSDGEGTLITAKPSNKEVTSLSVLDNVALLNFEGRGLLGKVGVDARIFKALSDQNISVS
IVSQGSSERGIGLIIDASKATQAVVALEREFENDFYTQDVNKIGVVDDVSVISIIGIELS
SFHKPFNALIKNQITPLLFNNTVTGRNVSLVVKKHQLHKAVNVIHGEIFGISKKINIAIF
GHGLVGGALINQILKSKDEIEKRKGISLNVFAIANSKQVILDKNGVDENWKEALKAETSG
YQLQDIVDFAKKHHLENLIAVDNTASGVFHENYKPLVEAGFDLVSSNKIANTISHDFYTD
LREHLKEHNKQYLYETTVGAGLPLIDTIKLLHESGENITRIRGVFSGTLSYLFNNFSVQD
KPFSTIVQETIDKGFTEPDPREDFSGNDVARKLLILARELDLHNEFEDVSVQNLIPEAYR
NISVQEFLGQLDVLDEEFQKIKEQQEPGNVLRYVGDLFGDLSQEKGNLEVKLVSIPEDST
LGHVKGSDAIFEIFTESYGEQPIVIQGAGAGAEVTARGVFGDILRLSKHIN
NT seq
3396 nt
NT seq
+upstream
nt +downstream
nt
atgaaagcacttaaattcatacaactggataattttactcttgaaagcggagtggagttg
ccaattcaattatcgtatcaaacctttgggttgccgcttcatgaagccccaatagtagtg
gttaatcatgccttaaccgggaacagcaatgtggctggaagtgatggttggtggggcagt
ttgattggcgatgacaaaattatcgataccaaaaagttcacggttctagcctttaatatt
ccaggtaatgggtacgacggattcctgattgaaaactataaggattttgtggcgcgtgat
gttgccaaattgtttttaaaaggcctagaagaattaaacattcaacaggtgtttgccttg
ataggcggttcgcttggaggcggaattgcttgggaaatggccgttttgaaacctaaacta
gccgagtatttaatccccgtggcaaccgattggaaatcgaccgattggttgattgccaat
tgtcaaattcaagagcagtttttggtgaattccaacaatccggtgcacgatgcccgaatg
cacgccatgctatgctacagaacgcctaagtcgtttaaggagcgtttccaaagaagtata
aacaatgaattggaaattttcaatgtagaaagttggttgctgcatcatggtaataagttg
caagaacgttttcagttgtcggcttataaattgatgaaccagttgctgaaaaccattgac
gttaccaaaggaagagaagccaacgaaaatatattggacattatcagttccaaaattgcc
attgtgggtgtggattctgatttattttttactgcggaagaaaacagggaaacccaaaaa
cagctagctgcaacacatccaaatgtgacctatcacgaaatccattcagatcatggtcac
gatgcatttttaatagaatttgaacaattagaaaaaattatagagggtatttttagccca
gatacaaaacacaagagaatgaaaatattgaagtttggcgggaagtctttagcaaatgga
gaaggtcttacaagagcccttgaaatcatagagaaaaaggttagtgatggcgaaaaaata
gcagtggttgtatcggctagagggaatgccacggacgaattggaagctttgcttgaaaaa
gcttctaagaaggaagtgtacaaatccgattttgaagctttcaaggcctatcaagtagaa
ccattgccaagtattgattttacaagtgagttttcggctttggaaaatattttcgaaggg
gtggctttgcttggggattatagtgaaaaaatcaaaagccaagtattggctttcggggaa
ttattgtctgccaaaattattgcagaaatattaaaaagcaaaggcattaatgctaatgca
accgactctagaaccttaataaaaacagaaggtgattttggaaattcgcaaccgattcaa
aagatttccaaagagaaggtggtggagcattttaagaaattcaatggttctacggtgaat
attgttacagggttcatagcatcgaatttggatggagaaacaacgactttgggacgcaac
ggaagcaactattcggcatctttattggctaatttcttggatgcagaagaattgcaaaat
tatacacatgtaaatggtatttatacggccaatccagacttggttgccgatgctcaaaaa
attagagagctgtcctttagtgaagccaatgaactggcaaattttggaacgagtgtgctg
catgccaaaaccatcattccattggtggaaaaaaatatcaatttaagaatcctgaatact
ttcaattccgatggggaaggtaccttgattacggctaaaccaagcaataaggaagtcact
tcattgtcggttttggataatgtggcgctattgaattttgaaggaagaggtcttttaggg
aaagttggggtagatgcccgaatttttaaagccttgagtgaccaaaatatcagtgtcagt
attgtgtctcaaggatcttcggaaagaggaattggtttgatcatagatgcttcaaaagca
acgcaagctgttgtggctttggagcgcgagtttgaaaatgatttttacacacaagacgtt
aacaaaattggtgtagtagatgatgtgtcggtaatctctattattgggattgagttgagt
tcgttccataagccattcaatgccttgatcaaaaaccaaattacaccactattgtttaac
aatacggtgacgggtagaaatgtgagtttggtggtgaaaaagcatcagttacacaaggct
gtaaatgttattcatggggagatttttggaatttccaagaaaatcaacattgccattttt
ggccatggattggttggaggtgctttgatcaatcagattttgaaatcgaaagatgaaatt
gaaaagcgcaagggaatcagcttgaatgtattcgctatagctaattcaaaacaggtgatt
ttagataaaaatggcgtcgatgaaaattggaaagaagccttgaaagctgaaacttcagga
tatcaacttcaggatatagtggatttcgccaaaaaacaccatttggaaaacttgatcgct
gtggacaataccgcaagcggggtgtttcatgaaaactacaagccattggtggaagcggga
tttgatttggtgtcgtcgaataaaattgccaacaccatttcccacgatttttacaccgat
ttaagagaacacttaaaagagcacaacaaacaatatctttacgaaactaccgtaggtgct
ggattgccattaattgacaccataaaattactgcacgaatctggtgaaaacatcaccagg
attagaggggtgttttcaggaacgttaagttacctgttcaataatttttctgttcaggac
aaaccatttagtacaattgttcaggaaactattgataaaggatttacggagccagatcca
agagaagatttctcagggaatgatgtcgcgcgtaaactgttgatcttggctcgtgaattg
gatttgcataacgaatttgaagatgtttctgttcaaaatttaatccctgaagcttataga
aatatttcagttcaggaatttttggggcaattggatgtgcttgatgaggaattccaaaaa
atcaaagaacaacaggaaccgggcaatgtgttgagatatgttggagatttgtttggtgac
ctgtcgcaggagaaagggaatttggaagtaaaattggtttccattccagaagacagcact
ttgggtcatgtaaaaggttccgatgccatttttgaaatttttacagaatcttatggagag
cagccaattgtgatccaaggggcaggcgcaggtgccgaagtaaccgccagaggggtcttt
ggggatattttaagactgtccaaacacattaactaa
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