Mannheimia pernigra ZY170218: GM695_03585
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Entry
GM695_03585 CDS
T06423
Symbol
gshAB
Name
(GenBank) bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
mann
Mannheimia pernigra ZY170218
Pathway
mann00270
Cysteine and methionine metabolism
mann00480
Glutathione metabolism
mann01100
Metabolic pathways
mann01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
mann00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
GM695_03585 (gshAB)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
GM695_03585 (gshAB)
Enzymes [BR:
mann01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
GM695_03585 (gshAB)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
Dala_Dala_lig_C
ATP-grasp_3
ATPgrasp_ST
GARS_A
GSH-S_ATP
ATP-grasp
Motif
Other DBs
NCBI-ProteinID:
QHB17180
LinkDB
All DBs
Position
complement(710949..713225)
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AA seq
758 aa
AA seq
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MKLQQIIQENHLGLLFQQGNFGLEKESQRIDKEGNIVTTPHPAVFGNRAYHPYIQTDFAE
SQLELITPANAKLEDSFRWLSAIHEVVLRSLPEDEYIFPLSMPAGLPPEELILEAQFDNP
EDVNYRKYLSANYGKYKQMVSGIHYNFQLSPEFVEKAFALQTEYPNLKTFQNVLYMKLAN
NFLRYQWIFIYLLAATPTVESQYFYHKSPLAEGQLVRSLRSSPYGYVNSEQVVVNHDSLE
SYVETLETQVSKGLLIAEKEFYSNVRLRGGKKARDLLEKGVQYVEFRLFDLNPFAPYGIE
LSDAKFIHYFLLGMLWLEETSGQKEVEIGKQKLYQVALEDPRTETAFRTEGEAILNHILA
MLEALGTSEENLELVREKIAQFADPTKTINGRLLKAIDQFGSYKALGAKLAQDYKNQAFD
RFYALSAFDNMELSTQALFFDLIQQGIGVELLDENDQFLALKFGNHLEYVKNGNMTSHDQ
YISPLIMENKVVTKKVLAKAGFNVPKSVEFTTLEEAVAHYPLFEGKAVVIKPKSTNYGLG
ITIFQQAVKNREDFAKAVEIAFREDKEVMVEDYLTGTEYRFFVLGSETLAVLLRVPANVV
GDGVHTIKELVEMKNDDPLRGDGSRSPLKKITLGEIEQLQLKEQGLTVDAVPERGQAVQL
RANSNISTGGDSIDMTDQMHESYKQIAASIARTMGAKVCGVDLIIPDLTQAAEPNLSSWG
VIEANFNPMMMMHIFPYQGKSRRLTKAVIKMLFPEINH
NT seq
2277 nt
NT seq
+upstream
nt +downstream
nt
atgaaactacaacaaattatccaagaaaatcatttaggattactatttcaacaaggaaat
tttgggttagaaaaagagagtcaacgtattgataaagaaggtaatattgttacaacccca
cacccagcagtatttggaaatcgcgcttatcacccttatatccagactgattttgccgaa
agtcagctagaactaattactcctgcgaatgcgaaattggaagacagtttccgctggtta
tccgcaatacacgaggtggttttacgctctttaccagaagatgaatacatcttcccactc
agtatgcccgcgggtttaccgcctgaagagttaatcttagaagcacaatttgataaccct
gaagatgtaaactaccgcaaatacctctcggctaactatggtaaatacaaacaaatggta
agcggcatacattataacttccagctttcacctgagtttgttgaaaaagcatttgctttg
caaactgaataccctaatttgaaaacattccaaaatgtactttatatgaagttagcgaat
aacttcctgcgttatcaatggattttcatttatttattggccgccaccccaaccgtggaa
tcgcaatatttttatcataaatcaccgcttgcagaagggcaattagtgcgtagtttacgc
tctagtccttatggttatgtcaattcagagcaagttgtggtgaatcacgacagtttagaa
agctatgtcgaaacccttgaaacacaagtttcaaaaggcttactcattgcagaaaaagag
ttctattctaacgtgcgtttgcgtggcggtaaaaaggcacgagacttactggaaaaaggc
gtgcaatacgtggaattccgcctgttcgatctcaatccatttgcaccttatggtattgaa
ttaagtgatgcgaaatttatccactatttcttgcttggtatgctttggttggaagaaaca
agcggtcaaaaagaggtagaaattggcaaacagaaactttaccaagtcgcacttgaagat
cccagaactgaaaccgccttccgtactgaaggagaagccatcttaaatcacattttagcg
atgcttgaagcgttaggaacaagcgaagagaatctagagctcgtgcgtgaaaaaatcgct
cagtttgccgatcccacaaaaaccattaatggacgcttacttaaagccatcgatcaattc
ggtagctataaagcactaggtgcaaaactcgctcaagattataaaaatcaagcgtttgat
cgtttttatgccctgtctgcttttgacaatatggagctttctactcaggcgttattcttt
gatttaatccaacaaggaattggggtggaattgctcgatgaaaacgatcaatttctcgcc
ctgaaatttggcaatcatttggaatatgtaaaaaatggcaatatgaccagccacgatcaa
tacatttcgccattgattatggaaaataaagtggtgacgaaaaaagtactggcaaaagca
ggtttcaatgtgccaaaaagtgtcgaatttaccacacttgaagaggcagtcgctcactat
ccgctgtttgagggcaaggctgtggtgatcaagccgaaatccaccaactacggattaggc
atcacgattttccaacaagcggtcaaaaatcgggaagattttgcaaaagcggtagaaatt
gcgttccgtgaagacaaagaagtgatggtagaagattatttgactggcaccgaataccgc
ttctttgtgttaggcagtgaaacccttgccgtgcttctgcgtgtgcctgccaatgtagtc
ggagatggcgttcataccattaaagaattggttgaaatgaaaaatgacgatccactcaga
ggcgatggctctcgtagccctcttaaaaaaatcaccttaggcgaaatcgaacagttacaa
ctaaaagagcaaggcttaactgtcgatgctgtgcctgagagaggtcaagccgtgcaactg
cgtgccaattctaatatcagcacagggggcgattcgattgatatgaccgaccaaatgcac
gaaagctataaacaaattgctgccagcattgctcgtactatgggagcgaaagtgtgtggc
gtggatttaattattcccgatctcactcaagctgccgagccaaatttaagctcttgggga
gtgattgaagcaaacttcaatccaatgatgatgatgcatattttcccctatcaaggaaaa
tctcgccgtctaaccaaagcagtgattaaaatgttatttccagaaataaatcattaa
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