Mannheimia pernigra ZY170218: GM695_10095
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Entry
GM695_10095 CDS
T06423
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
mann
Mannheimia pernigra ZY170218
Pathway
mann00260
Glycine, serine and threonine metabolism
mann00261
Monobactam biosynthesis
mann00270
Cysteine and methionine metabolism
mann00300
Lysine biosynthesis
mann01100
Metabolic pathways
mann01110
Biosynthesis of secondary metabolites
mann01120
Microbial metabolism in diverse environments
mann01230
Biosynthesis of amino acids
Module
mann_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
mann_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
mann_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
mann00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
GM695_10095 (thrA)
00270 Cysteine and methionine metabolism
GM695_10095 (thrA)
00300 Lysine biosynthesis
GM695_10095 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
GM695_10095 (thrA)
Enzymes [BR:
mann01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
GM695_10095 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
GM695_10095 (thrA)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
Sacchrp_dh_NADP
DapB_N
B12-binding_2
DUF1131
Motif
Other DBs
NCBI-ProteinID:
QHB18339
LinkDB
All DBs
Position
2030493..2032949
Genome browser
AA seq
818 aa
AA seq
DB search
MRVLKFGGTSLANPERFMQAADIIEKAHLADQAAGVLSAPAKITNHLVAIVDKAIAGESF
ESNLSEATEIFHNIINGLYEANNNFAKNELLALVDAELTQIQQVAADSAKSKSLSDDIAA
TIHCRGEKLSIAMMQAWFEAKGYTVTRIDPVEKLLAHGSYLESSVDIPESTQRVDAGSIP
KKNVVLMAGFTAGNKQGELVLLGRNGSDYSAACLAACLKADVCEIWTDVDGVYTCDPRLV
PDAVCLESMSYQEAMELSYFGAKVIHPRTIGPLVSLNIPCLIKNTGNPESKGTLIDGNVA
NDNLKVKGITNLDNVAMFNVSGAGMQGMVGMAARVFSTMSKSGISVILITQSSSEYSISF
CVPAKSAEKALLALNAEFAQELAENLLDPIDIIKDLSIVSVVGDGMRTAKGIAARFFSAL
AQANISIVAIAQGSSERSISAVVPLNKAIEAVKATHKSLFNSKRVVDIFLVGVGGVGSEL
IEQVKQQKEFLAKKDIEIRICALANSDKMLLNESGLNLDNWKEDLEKAIQPSDFDVLLSF
IKFHHVVNPVFVDCTSAQSVANLYARALKEGFHVITPNKKANTSGYNYYLEMRENARQSQ
HKFLYETNVGAGLPVIENLQNLLAAGDEVEKFEGILSGSLSFIFGKLEEGLTLSQATLLA
KEKGFTEPDPREDLSGADVARKLLILARETGLPLEFEDIEIEGILPKGFSEGMNRDEFLE
ALPALDEEFNKRVEAAKAEGKVLRYVGSITGTKCRVAIEIVDDNHPLYKVKDGENALAFL
TRYYSPIPLLLRGYGAGNSVTAAGIFADILRTLPGGAS
NT seq
2457 nt
NT seq
+upstream
nt +downstream
nt
atgcgagttcttaaatttgggggcacctctcttgccaatccagaacgctttatgcaagcg
gcggatattatcgaaaaagcccatttagctgatcaggcggcaggggttttatccgctcca
gccaaaatcactaaccacttggtcgccattgttgataaagcaattgctggcgaatcattt
gaatctaacctttctgaagcaaccgagattttccacaacatcattaacggcttatatgaa
gcaaacaataactttgccaaaaatgaactattagcattggttgatgctgaattaacccaa
attcagcaagttgcggcagattctgcaaaaagtaaatcactctcggatgatattgcagca
acaatccattgccgtggtgaaaaactttctattgcaatgatgcaagcgtggtttgaagca
aaaggctacaccgttactcgcatcgaccctgttgaaaaattattggctcacgggagctat
ttggaatcttcagttgatattccagaatcgactcaacgtgttgatgcaggctcgattccc
aagaagaatgtggtattaatggcaggttttactgcaggcaataagcaaggtgaattagtg
ctattagggcgaaatggatctgattactctgccgcttgtttagccgcttgcttgaaagca
gatgtctgtgaaatttggacagatgtggatggtgtttacacttgcgatcctcgcctagtg
cccgatgcggtttgtttggaatctatgagctaccaagaagcgatggagctttcttacttc
ggggcaaaagtgattcatcctcgcacaatcgggcctttagtatcattaaatattccgtgc
ttaattaaaaatacaggtaatcctgaaagcaaaggcaccttgattgatggtaatgttgca
aatgataatttgaaagtaaaaggcattactaaccttgataacgtcgcaatgtttaacgta
tcaggtgcgggtatgcagggaatggtgggtatggctgctcgtgttttctctacaatgtcg
aaatcaggcatttcagtgattttaattacccaatcttcatcagaatatagtattagtttc
tgtgtgcctgctaaatcagcagaaaaagcgttacttgcattaaatgcggaatttgcccaa
gagttagctgaaaacttacttgatccgattgatattattaaagatttatctatcgtttct
gtagtaggtgacggtatgcgtaccgctaaaggtatcgcagcacgctttttctctgcactt
gctcaagcaaacattagtattgttgcgatcgcacaaggttcatcagagcgttcaatttca
gcagtggtgccactgaataaagccattgaagccgtgaaagccacccataaatcattattt
aatagcaaacgtgttgtagatatttttttagttggcgttggcggtgttggaagtgagtta
attgagcaagtaaaacaacaaaaagagtttctagccaaaaaggatattgaaattcgtatt
tgtgccttagctaattcagataagatgttgcttaacgaaagcggtttaaatttagataac
tggaaagaagatttagaaaaagcaatccaaccctcagactttgatgtactactttctttt
atcaaattccaccacgtggtcaatcctgtgtttgttgattgcacctcggcacaatctgta
gcaaacctttacgcccgagcgttaaaagaaggcttccatgtgattacaccaaacaaaaaa
gccaatacgtcaggctataactattacttagaaatgcgtgagaatgctcgtcaaagccag
cacaaattcctttatgaaactaacgtaggggcaggtttacccgttatcgaaaatctacaa
aacttgctagcagctggcgatgaagtagagaaatttgaggggattctttcaggctcactc
tcattcattttcggtaaattagaagagggcttaacgctttctcaagctaccctattggca
aaggaaaaaggctttactgagcctgatcctcgtgaggatttatcaggtgccgatgtggct
cgcaaattattaattttagctcgtgaaactggcttgccgcttgaatttgaagatattgaa
attgaaggcatattaccaaaaggcttctccgaaggaatgaaccgtgatgagtttttagaa
gcattgcctgcattagatgaagaatttaacaaacgtgtagaagcagccaaagcagaaggt
aaagtattacgctatgtaggctcaattacagggacaaaatgccgtgtggcaattgaaatt
gttgatgacaatcacccactttataaagtaaaagatggcgaaaatgctcttgccttctta
actcgctactacagcccaatcccccttctcttgcgtggttatggtgcaggtaatagcgta
actgcagcaggtatttttgctgatattcttcgtacattaccaggaggtgcaagctaa
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