KEGG   Mirounga angustirostris (Northern elephant seal): 123839807
Entry
123839807         CDS       T11530                                 
Symbol
TBC1D4
Name
(RefSeq) TBC1 domain family member 4 isoform X1
  KO
K17902  TBC1 domain family member 4
Organism
mano  Mirounga angustirostris (Northern elephant seal)
Pathway
mano04910  Insulin signaling pathway
mano04919  Thyroid hormone signaling pathway
mano04931  Insulin resistance
mano05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mano00001]
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    123839807 (TBC1D4)
   04919 Thyroid hormone signaling pathway
    123839807 (TBC1D4)
 09160 Human Diseases
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    123839807 (TBC1D4)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    123839807 (TBC1D4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mano04131]
    123839807 (TBC1D4)
Membrane trafficking [BR:mano04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    123839807 (TBC1D4)
 Protein recycling
  Rab GTPases and associated proteins
   Other Rab GTPase associated proteins
    123839807 (TBC1D4)
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   Rab associated proteins
    123839807 (TBC1D4)
SSDB
Motif
Pfam: RabGAP-TBC RabGap-TBC_2 TBC1D_hel DUF3350 PID DUF4249 Microvir_J HAD_PNKP
Other DBs
NCBI-GeneID: 123839807
NCBI-ProteinID: XP_045725524
LinkDB
Position
Unknown
AA seq 1291 aa
MEPPSCIQDEPFPHPLEPEPGAPAQPGPGKPGDKRFRLWYVGGSCLDRRTTLPMLPWLMA
EIRRRSQKPEAGGCGAPAAREVLLVLSAPFLRCVPAPGVGAAGCLGPAATQPNPAVFIFE
HKAQHISRFIHNSHDLTYFAYLIKAQPDDPESQMACHVFRATDPNQVPDVISSIRQLSKA
AMKEDAKAGKDNGDAFYNSQKFEVLYCGKVTVAHKKAPSSLIDDCIEKFSLHEQQRLRTQ
GEQRGADAGVDPGVLEAAAPGPAAHILSEEGDGVPSTQPALPAGASQPGLPSSRAGFPER
ILEDSGFDERQEFRSRCRSVTGVLQRKAQENSQKPPPRRRHASAPSHVQPSDSEKNRTML
FQVGRFEINLISPDTKSVVLEKNFKDISSCSQGIKHVDHFGFICRESAEPGMSQYICCVF
QCASESLVDEVMLTLKQAFSTAAALQSAKTQIKLCEACPMHSLHKLCERIEGLYPPRAKL
VIQRHLSSLTDNEQADIFERVQKMKPVGDQEENELVILHLRQLCEAKQKTHIHIGEGPST
ISNSIIPENATSSGRFKLDILKNKAKRSLTSSLENIFSRGANRMRGRLGSMDSFERSNSL
ASEKDYSPGDSPPGTPPASPLSSAWQTFPEEDSDSPQFRRRAHTFSHPPSSTKRKLNLQD
GRAHGVRSPLLRQSSSEQCGILPSVRRMHKESNSSSSLPSLHTSFSAPSFTTPSFLKSFY
QNSGRLSPQYENEISDGEGRKRTSSTCSNESLNAGGTPVTPRRISWRQRIFLRVASPMNK
SPSAMQQDGLDRNELLPLSPLAPTMEEEPLIIFTSGKDDSEKAEERRKSEELRSLWRKAI
HQQILLLRMEKENQKLEASRDELQSRKVKLDYEEVGVCQKEVLITWDKKLLNCRAKIRCD
MEDIHISLKEGVPKTRRGEIWQFLALQYRLRHRLPNKQQPPDISYKELLKQLTAQQHAIL
VDLGRTFPTHPYFSAQLGAGQLSLFNLLKAYSLLDKEVGYCQGISFVAGVLLLHMSEEQA
FEMLKFLMYDQGFRKQYRPDMMSLQIQMYQLSRLLHDYHRDLYNHLEENEISPSLYAAPW
FLTLFASQFPLGFVARVFDIIFLQGTEVIFKVALSLLSSQETLIMECENFESIVEFLKTT
LPDMNTSEMEKIITQVFEMDISKQLHAYEVEYHVLQDELQESSYACEDSEPMEKLERANS
QLKRQNMDLLEKLQIAHAKIQTLESNLENLLTRETKMKSLIRTLEQEKVAYQKTVDQIRK
LLPADALASCESLLRDLTCNPNNKAKTGNKP
NT seq 3876 nt   +upstreamnt  +downstreamnt
atggagccccccagctgcattcaggatgagccgttcccgcaccctctggagcccgagccg
ggcgcccctgcgcagccgggccccgggaagccgggcgacaaacggtttcggctgtggtac
gtgggggggtcgtgcctggaccgcaggaccacgctgcccatgctgccctggctcatggct
gagatccgccggcgcagccagaagcccgaggcgggcggctgcggggcgccggccgcccgc
gaggtgctcctggtgctcagcgcgcccttcctgcgctgtgtccccgctccgggcgtcggg
gccgcggggtgcctaggccccgcggcgacgcagcccaacccggcggtgttcatcttcgag
cacaaggcacagcacatctcgcgcttcattcacaacagccacgatctcacctactttgcc
tacctgatcaaggcgcagcccgacgaccctgagtcgcagatggcctgccacgttttccgc
gccacagaccccaatcaggttccggatgtgatcagcagcataaggcagttatccaaagct
gccatgaaagaggatgccaaggccggcaaagacaacggggatgccttttacaactctcag
aagttcgaagtcctgtactgcgggaaggtgacggtggcccacaagaaggccccgtcgagc
ctcatcgacgactgcattgagaagttcagcctgcacgagcagcagcgcctgaggacgcag
ggcgagcagcgcggcgcggacgcgggcgtcgacccgggggtcctcgaggccgcggcgccc
ggcccagccgcccacatcctgtccgaggaaggggacggcgtccccagcacccagcctgcc
ttaccggccggggccagccagccggggctgcccagctcgcgagctggcttcccggagcgg
attctggaagattctggctttgatgagcgacaggagttccggtctcggtgcaggagcgtc
accggagtcttgcaaaggaaagctcaggagaacagccaaaaaccaccgccgcgacggagg
cacgccagtgcgccgagccacgtgcagccgtcggattcggagaagaacaggacgatgctg
ttccaggttgggcggtttgagattaaccttatcagtccagacaccaaatcagttgtgctc
gaaaagaattttaaagatatctcttcttgttctcagggtatcaagcatgtagatcatttt
ggcttcatctgtcgggagtcagcagagcccgggatgagccagtacatctgctgtgtgttc
cagtgtgccagtgagtccctggtcgatgaggtaatgctgactctgaaacaggccttcagc
accgcagctgccctgcagagtgccaagacccagattaagctgtgtgaggcctgccctatg
cactctttgcataagctctgtgaaaggattgaaggtctctaccccccgagagccaagctg
gtaatacagaggcatctctcatcactgacagataacgagcaagcagacatctttgagcga
gttcagaaaatgaagccagtcggtgaccaggaggagaatgaacttgtgattttacatttg
aggcagctgtgtgaggccaagcagaagacacacattcacattggagaaggcccatcgact
atttcaaatagtataatcccggaaaatgcaacaagcagtggaaggttcaaacttgacatt
ctgaaaaataaagctaagagatctttaactagctccctggaaaatatcttctcaagggga
gctaacagaatgagaggtcggcttggaagtatggacagctttgaacgatccaacagtctt
gcttcggagaaggactattcaccaggagactctccaccggggacaccaccagcctcccca
ctgtcctcagcttggcaaacgttccctgaagaggattcggactccccacagtttcgaaga
cgggcgcacacgttcagccacccaccttcaagcacaaagagaaagctgaatttgcaggat
gggagagctcatggtgttcgctcccctcttctgaggcagagctccagcgagcagtgcggc
attcttccatcagtgcggcgcatgcacaaggagagtaactcttcctccagccttccaagt
ctacatacttccttctctgccccttccttcactaccccctctttcctgaaaagcttttac
cagaattcaggtagactgtccccacagtatgaaaatgaaatcagcgatggagaagggaga
aaaaggacctcgtctacttgcagtaatgaatccctaaacgctggaggaacccctgttacc
cctcgtcgaatctcctggcggcagcgcatttttctcagggttgcttctcccatgaacaaa
tctccctcagcgatgcagcaggatggactggacaggaacgaactgctaccactgtcccct
cttgctccaaccatggaggaggaaccgctgattatattcacgtctggcaaagatgactca
gagaaggctgaagaaagaaggaaatcagaagaactgaggagtttgtggagaaaagccata
caccaacaaatcttgttgcttcgaatggagaaagaaaaccagaaacttgaagcaagcaga
gatgaactccagtccagaaaagttaaactggactatgaagaagttggtgtatgtcagaag
gaggtcttaataacctgggataagaagttgttgaactgcagagctaaaatcagatgtgat
atggaagatattcatatttctcttaaagaaggtgttcccaaaactcgacgaggagaaatt
tggcagttcctagctttacagtatcgtctaaggcacaggttgcccaataaacaacaacct
cctgacatatcctataaagaacttttaaagcagctcactgctcaacagcatgctattctt
gtggatttgggaaggacatttcctactcacccttatttttcagcacagcttggggcaggg
cagctctcactctttaacctcttgaaagcctactcactgctggacaaagaagtgggttac
tgtcaggggatcagctttgtggctggagtcctccttctgcacatgagcgaagagcaagcc
tttgagatgctgaaattcctcatgtatgaccagggcttccgcaagcagtacagacctgac
atgatgtcactgcagattcagatgtaccagctgtccaggctccttcatgactatcacaga
gatctctacaatcatcttgaagaaaatgaaatcagccccagtctttatgctgccccctgg
ttcctcacattgtttgcctctcaatttccactaggatttgtagccagagtttttgatatt
atttttcttcagggaactgaagttatatttaaggttgcactcagtctgctgagcagccag
gagacacttataatggaatgtgaaaactttgaaagtattgtcgaatttcttaaaaccaca
ctacctgatatgaatacatctgaaatggaaaaaattattacccaggtttttgagatggat
atatctaaacagttacatgcctatgaggtggaatatcacgtgctgcaggatgagcttcag
gaatcatcatatgcttgtgaggatagtgaacctatggagaagctggagagggccaatagc
caactgaaaagacaaaacatggacctcctagaaaagttacagatagctcatgctaaaatc
cagaccttggaatccaatctggaaaaccttctgaccagagagaccaaaatgaagtcttta
atccggactctggaacaagagaaagtggcttatcaaaagacagtggatcagatccggaag
ctgctgccagccgatgcgctcgccagctgcgaatcattgctaagagacctcacctgcaac
cctaacaacaaagccaagacaggaaacaagccataa

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