KEGG   Mirounga angustirostris (Northern elephant seal): 123843118
Entry
123843118         CDS       T11530                                 
Symbol
MAPK11
Name
(RefSeq) mitogen-activated protein kinase 11 isoform X3
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
mano  Mirounga angustirostris (Northern elephant seal)
Pathway
mano01522  Endocrine resistance
mano04010  MAPK signaling pathway
mano04015  Rap1 signaling pathway
mano04068  FoxO signaling pathway
mano04071  Sphingolipid signaling pathway
mano04114  Oocyte meiosis
mano04148  Efferocytosis
mano04218  Cellular senescence
mano04261  Adrenergic signaling in cardiomyocytes
mano04370  VEGF signaling pathway
mano04380  Osteoclast differentiation
mano04517  IgSF CAM signaling
mano04550  Signaling pathways regulating pluripotency of stem cells
mano04611  Platelet activation
mano04613  Neutrophil extracellular trap formation
mano04620  Toll-like receptor signaling pathway
mano04621  NOD-like receptor signaling pathway
mano04622  RIG-I-like receptor signaling pathway
mano04625  C-type lectin receptor signaling pathway
mano04657  IL-17 signaling pathway
mano04658  Th1 and Th2 cell differentiation
mano04659  Th17 cell differentiation
mano04660  T cell receptor signaling pathway
mano04664  Fc epsilon RI signaling pathway
mano04668  TNF signaling pathway
mano04670  Leukocyte transendothelial migration
mano04714  Thermogenesis
mano04722  Neurotrophin signaling pathway
mano04723  Retrograde endocannabinoid signaling
mano04728  Dopaminergic synapse
mano04750  Inflammatory mediator regulation of TRP channels
mano04912  GnRH signaling pathway
mano04914  Progesterone-mediated oocyte maturation
mano04917  Prolactin signaling pathway
mano04926  Relaxin signaling pathway
mano04932  Non-alcoholic fatty liver disease
mano04933  AGE-RAGE signaling pathway in diabetic complications
mano04935  Growth hormone synthesis, secretion and action
mano04936  Alcoholic liver disease
mano05014  Amyotrophic lateral sclerosis
mano05020  Prion disease
mano05022  Pathways of neurodegeneration - multiple diseases
mano05132  Salmonella infection
mano05133  Pertussis
mano05135  Yersinia infection
mano05140  Leishmaniasis
mano05142  Chagas disease
mano05145  Toxoplasmosis
mano05152  Tuberculosis
mano05161  Hepatitis B
mano05163  Human cytomegalovirus infection
mano05167  Kaposi sarcoma-associated herpesvirus infection
mano05169  Epstein-Barr virus infection
mano05170  Human immunodeficiency virus 1 infection
mano05171  Coronavirus disease - COVID-19
mano05205  Proteoglycans in cancer
mano05208  Chemical carcinogenesis - reactive oxygen species
mano05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mano05415  Diabetic cardiomyopathy
mano05417  Lipid and atherosclerosis
mano05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mano00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123843118 (MAPK11)
   04015 Rap1 signaling pathway
    123843118 (MAPK11)
   04370 VEGF signaling pathway
    123843118 (MAPK11)
   04668 TNF signaling pathway
    123843118 (MAPK11)
   04068 FoxO signaling pathway
    123843118 (MAPK11)
   04071 Sphingolipid signaling pathway
    123843118 (MAPK11)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    123843118 (MAPK11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    123843118 (MAPK11)
  09143 Cell growth and death
   04114 Oocyte meiosis
    123843118 (MAPK11)
   04218 Cellular senescence
    123843118 (MAPK11)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    123843118 (MAPK11)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    123843118 (MAPK11)
   04613 Neutrophil extracellular trap formation
    123843118 (MAPK11)
   04620 Toll-like receptor signaling pathway
    123843118 (MAPK11)
   04621 NOD-like receptor signaling pathway
    123843118 (MAPK11)
   04622 RIG-I-like receptor signaling pathway
    123843118 (MAPK11)
   04625 C-type lectin receptor signaling pathway
    123843118 (MAPK11)
   04660 T cell receptor signaling pathway
    123843118 (MAPK11)
   04658 Th1 and Th2 cell differentiation
    123843118 (MAPK11)
   04659 Th17 cell differentiation
    123843118 (MAPK11)
   04657 IL-17 signaling pathway
    123843118 (MAPK11)
   04664 Fc epsilon RI signaling pathway
    123843118 (MAPK11)
   04670 Leukocyte transendothelial migration
    123843118 (MAPK11)
  09152 Endocrine system
   04912 GnRH signaling pathway
    123843118 (MAPK11)
   04914 Progesterone-mediated oocyte maturation
    123843118 (MAPK11)
   04917 Prolactin signaling pathway
    123843118 (MAPK11)
   04926 Relaxin signaling pathway
    123843118 (MAPK11)
   04935 Growth hormone synthesis, secretion and action
    123843118 (MAPK11)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    123843118 (MAPK11)
  09156 Nervous system
   04728 Dopaminergic synapse
    123843118 (MAPK11)
   04723 Retrograde endocannabinoid signaling
    123843118 (MAPK11)
   04722 Neurotrophin signaling pathway
    123843118 (MAPK11)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123843118 (MAPK11)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    123843118 (MAPK11)
  09159 Environmental adaptation
   04714 Thermogenesis
    123843118 (MAPK11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    123843118 (MAPK11)
   05208 Chemical carcinogenesis - reactive oxygen species
    123843118 (MAPK11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    123843118 (MAPK11)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    123843118 (MAPK11)
   05161 Hepatitis B
    123843118 (MAPK11)
   05171 Coronavirus disease - COVID-19
    123843118 (MAPK11)
   05163 Human cytomegalovirus infection
    123843118 (MAPK11)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123843118 (MAPK11)
   05169 Epstein-Barr virus infection
    123843118 (MAPK11)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123843118 (MAPK11)
   05135 Yersinia infection
    123843118 (MAPK11)
   05133 Pertussis
    123843118 (MAPK11)
   05152 Tuberculosis
    123843118 (MAPK11)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    123843118 (MAPK11)
   05140 Leishmaniasis
    123843118 (MAPK11)
   05142 Chagas disease
    123843118 (MAPK11)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    123843118 (MAPK11)
   05020 Prion disease
    123843118 (MAPK11)
   05022 Pathways of neurodegeneration - multiple diseases
    123843118 (MAPK11)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123843118 (MAPK11)
   05418 Fluid shear stress and atherosclerosis
    123843118 (MAPK11)
   05415 Diabetic cardiomyopathy
    123843118 (MAPK11)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    123843118 (MAPK11)
   04932 Non-alcoholic fatty liver disease
    123843118 (MAPK11)
   04933 AGE-RAGE signaling pathway in diabetic complications
    123843118 (MAPK11)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    123843118 (MAPK11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mano01001]
    123843118 (MAPK11)
Enzymes [BR:mano01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     123843118 (MAPK11)
Protein kinases [BR:mano01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   123843118 (MAPK11)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH RIO1 Cas_CT1975
Other DBs
NCBI-GeneID: 123843118
NCBI-ProteinID: XP_045728239
LinkDB
Position
Unknown
AA seq 364 aa
MSGPRAGFYRLELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVG
TPSPEVLAKISSEHARTYIQSLPPMPQKDLRSIFHGANPLAVDLLGRMLVLDSDQRVSAA
EALAHAYFSQYHDPDDEPEAEPYDESVEAKERTVEEWKELTYQEVLSFKPAEPPQSPGSL
QIEQ
NT seq 1095 nt   +upstreamnt  +downstreamnt
atgtcgggcccgcgtgcaggcttctaccggctggagctcaacaagacggtgtgggaggtg
ccgcagcggctgcaggggctgcgcccggtgggctccggcgcctacggctcggtctgctca
gcctatgacgcgcggctgcgccagaaggtggcggtgaagaagctgtcgcgacccttccag
tctctgatccacgcgcggagaacttaccgcgagctgcggctgctcaagcacctgaagcac
gagaacgtcatcgggctgctggacgtgttcacgccggccacctccattgaggacttcagc
gaagtgtacctggtgaccaccctgatgggcgcggacctgaacaacatcgtcaagtgccag
gcgctgagcgacgagcacgtccagttcctggtttaccagttgctgcgcgggctcaagtac
atccactctgcggggatcatccaccgggacctgaagcccagcaacgtggctgtgaacgag
gactgcgagcttaggatcctggactttgggctagcccgccaggctgatgaggagatgact
ggctatgtggccactcggtggtaccgcgcacctgagatcatgctcaactggatgcactac
aaccagacagtggacatctggtctgtgggctgcatcatggctgagctgctccagggaaag
gccctctttccaggaaatgactacatcgaccagctgaagcgaatcatggaggtggtgggc
acacccagccctgaggttctagcaaagatatcctcagaacacgcccggacatacatccag
tccctgccccccatgccccagaaggacctcaggagcatcttccatggagccaaccccctg
gctgtggacctgctgggaaggatgctggtgctcgacagtgaccagagggtcagtgcggcc
gaggccctggcccatgcctacttcagccagtaccatgacccggacgatgagcctgaggct
gagccctatgatgagagcgttgaggccaaggaacgcacagtggaggagtggaaggagctc
acctaccaggaggtcctcagcttcaagcctgcagaaccaccgcagtctcccggcagcctg
cagattgagcagtga

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