KEGG   Mirounga angustirostris (Northern elephant seal): 123843233
Entry
123843233         CDS       T11530                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
mano  Mirounga angustirostris (Northern elephant seal)
Pathway
mano04010  MAPK signaling pathway
mano04022  cGMP-PKG signaling pathway
mano04137  Mitophagy - animal
mano04141  Protein processing in endoplasmic reticulum
mano04151  PI3K-Akt signaling pathway
mano04156  Integrated stress response (ISR) signaling pathway
mano04210  Apoptosis
mano04211  Longevity regulating pathway
mano04261  Adrenergic signaling in cardiomyocytes
mano04668  TNF signaling pathway
mano04720  Long-term potentiation
mano04722  Neurotrophin signaling pathway
mano04725  Cholinergic synapse
mano04728  Dopaminergic synapse
mano04911  Insulin secretion
mano04912  GnRH signaling pathway
mano04915  Estrogen signaling pathway
mano04918  Thyroid hormone synthesis
mano04922  Glucagon signaling pathway
mano04925  Aldosterone synthesis and secretion
mano04926  Relaxin signaling pathway
mano04927  Cortisol synthesis and secretion
mano04928  Parathyroid hormone synthesis, secretion and action
mano04932  Non-alcoholic fatty liver disease
mano04934  Cushing syndrome
mano04935  Growth hormone synthesis, secretion and action
mano05010  Alzheimer disease
mano05012  Parkinson disease
mano05014  Amyotrophic lateral sclerosis
mano05020  Prion disease
mano05022  Pathways of neurodegeneration - multiple diseases
mano05030  Cocaine addiction
mano05031  Amphetamine addiction
mano05034  Alcoholism
mano05161  Hepatitis B
mano05163  Human cytomegalovirus infection
mano05166  Human T-cell leukemia virus 1 infection
mano05203  Viral carcinogenesis
mano05207  Chemical carcinogenesis - receptor activation
mano05215  Prostate cancer
mano05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mano00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    123843233 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123843233 (ATF4)
   04668 TNF signaling pathway
    123843233 (ATF4)
   04022 cGMP-PKG signaling pathway
    123843233 (ATF4)
   04151 PI3K-Akt signaling pathway
    123843233 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    123843233 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    123843233 (ATF4)
   04156 Integrated stress response (ISR) signaling pathway
    123843233 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    123843233 (ATF4)
   04922 Glucagon signaling pathway
    123843233 (ATF4)
   04912 GnRH signaling pathway
    123843233 (ATF4)
   04915 Estrogen signaling pathway
    123843233 (ATF4)
   04926 Relaxin signaling pathway
    123843233 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    123843233 (ATF4)
   04918 Thyroid hormone synthesis
    123843233 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    123843233 (ATF4)
   04925 Aldosterone synthesis and secretion
    123843233 (ATF4)
   04927 Cortisol synthesis and secretion
    123843233 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    123843233 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    123843233 (ATF4)
   04728 Dopaminergic synapse
    123843233 (ATF4)
   04720 Long-term potentiation
    123843233 (ATF4)
   04722 Neurotrophin signaling pathway
    123843233 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    123843233 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    123843233 (ATF4)
   05203 Viral carcinogenesis
    123843233 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    123843233 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    123843233 (ATF4)
   05161 Hepatitis B
    123843233 (ATF4)
   05163 Human cytomegalovirus infection
    123843233 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    123843233 (ATF4)
   05012 Parkinson disease
    123843233 (ATF4)
   05014 Amyotrophic lateral sclerosis
    123843233 (ATF4)
   05020 Prion disease
    123843233 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    123843233 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    123843233 (ATF4)
   05031 Amphetamine addiction
    123843233 (ATF4)
   05034 Alcoholism
    123843233 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123843233 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    123843233 (ATF4)
   04934 Cushing syndrome
    123843233 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mano03000]
    123843233 (ATF4)
Transcription factors [BR:mano03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    123843233 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 CEP89 DUF4407 MCU BNI5_helical ATG38_C Nop53 AAA_13 DUF745 DUF3450 bZIP_Maf Asd-4
Other DBs
NCBI-GeneID: 123843233
NCBI-ProteinID: XP_045728445
LinkDB
Position
Unknown
AA seq 351 aa
MAEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
WLAVDGLVSASDNGKEDAFSGTDWMVEKMDLKEFDFDSLFSIDDLETMPDELLATLDDTC
DLFDPLVQETNKEPPRTVNPIGHLPESLQKTDQIAPFTFLQPLPLSPGALSSTPDHSFSL
ELGSEVDISEGDRKSDSATYSNVIPQCIKEEDAPSDNDSGICMSPESYLGSPQHSPSTSR
GSPNRSLLSPGSLSGSARPKPYDPPGEKTEAKVKVEKLDKKLKKMEQNKTAATRYRQKKR
AEQEALTGECKELEKQNEALKERADSLAKEIQYLKDLIEEVRKAREKKRVP
NT seq 1056 nt   +upstreamnt  +downstreamnt
atggccgagatgagtttcctgagcagcgaggtgttggtgggggacttgatgtcccccttc
gaccagtcgggtttgggggctgaggaaagcctgggtctcttagacgactacctggaggtg
gccaagcacttcaaacctcatgggttctccagcgacaaggctaaggcgggctcctccgaa
tggctggctgtggatgggttggtcagtgcctcagacaacggcaaggaggatgccttctcc
gggacagattggatggtggagaaaatggatctgaaggagtttgattttgattctctgttc
agtatagatgacctggaaaccatgccagatgagcttttggccacgttggatgacacgtgt
gatctctttgaccccctagtccaggagactaataaggagcccccccggactgtgaaccca
attggccatcttccagaaagtttacaaaaaacagaccagattgccccctttaccttcctc
caaccacttcccctctccccaggggccctgtcctccactccagatcattcctttagttta
gagctaggcagtgaagtggatatttctgaaggagatagaaagtcagactccgccacttac
agtaacgtgatccctcagtgcatcaaggaggaggatgccccctcagataatgatagtggc
atctgtatgagtcctgagtcctatctggggtccccccagcatagcccctctacctccagg
ggctctccaaataggagcctgctgtctccaggttccctctctggttctgcccgccccaaa
ccctatgaccctcctggagagaagacagaagcgaaagtaaaggtggagaaactagataag
aagctgaaaaaaatggagcagaacaagacagcagccactcggtaccgccagaagaagagg
gctgagcaggaggccctcactggggagtgtaaagagctggaaaagcagaatgaggctctg
aaagagagggcagattctttagccaaggagatccagtatctgaaagatttgatagaagag
gtccgaaaggcgagggagaagaaaagggtcccctag

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