KEGG   Mirounga angustirostris (Northern elephant seal): 123850446
Entry
123850446         CDS       T11530                                 
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
  KO
K12344  3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
Organism
mano  Mirounga angustirostris (Northern elephant seal)
Pathway
mano00140  Steroid hormone biosynthesis
mano01100  Metabolic pathways
mano05215  Prostate cancer
Module
mano_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:mano00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    123850446 (SRD5A2)
 09160 Human Diseases
  09162 Cancer: specific types
   05215 Prostate cancer
    123850446 (SRD5A2)
Enzymes [BR:mano01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.22  3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
     123850446 (SRD5A2)
SSDB
Motif
Pfam: Steroid_dh DUF1295
Other DBs
NCBI-GeneID: 123850446
NCBI-ProteinID: XP_045739687
LinkDB
Position
Unknown
AA seq 254 aa
MSVHCQQSPVLAGSATLAALGALVLYLAKPSGYGKYSESLMPAATRLPARAAWFLQELPS
FAVPAGILARQPRSLFGQPATVLLGLFCAHYFHRTFVYSLLTRGRPFPAAFLVRGFVFCM
GNGLLQAYYLVYCAEYPAEWYTDGRFSLGVFLFILGMGINIHSDYILRQLRKPGEVIYRI
PQGGLFTYVSGANFLGEVIEWTGYALATWSLPALAFAFFSLCFLGLRAFHHHRFYLKMFE
DYPKSRKALIPFIF
NT seq 765 nt   +upstreamnt  +downstreamnt
atgtccgttcactgccagcagagcccggtgctggcaggcagcgccactttggccgctctg
ggggcactggtcctgtacctcgcgaagccctccggctacgggaagtactcggagagcctg
atgcccgccgccacccgcctgcccgcgcgcgccgcctggttcctgcaggagctgccctcc
ttcgcggtgcccgcggggatcctcgcccggcagccgcgctcgctcttcggccagcccgcg
acggtgctcctgggcctcttctgcgcacattacttccacaggacctttgtttactcattg
ctcactagagggaggcctttcccagctgcgtttcttgtcagaggctttgtcttctgcatg
ggaaatggactgctccaagcctactatctggtttactgtgctgaataccctgctgagtgg
tacacagacggacggtttagcctgggtgtcttcttatttattttgggaatgggaatcaac
attcatagtgactacatattgcgccagctcaggaagcctggagaagtcatctataggatt
ccgcaaggtggcttgtttacgtatgtttccggagccaatttccttggtgaggtcattgaa
tggacgggctatgccctggccacttggtccctcccagcacttgcgtttgcgtttttctca
ctttgtttcctggggctgcgagccttccaccaccacaggttctacctcaagatgtttgag
gactatcccaaatctcggaaggccctcattccatttattttttga

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