Mirounga angustirostris (Northern elephant seal): 123851004
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Entry
123851004 CDS
T11530
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1 isoform X1
KO
K03099
son of sevenless
Organism
mano Mirounga angustirostris (Northern elephant seal)
Pathway
mano01521
EGFR tyrosine kinase inhibitor resistance
mano01522
Endocrine resistance
mano04010
MAPK signaling pathway
mano04012
ErbB signaling pathway
mano04014
Ras signaling pathway
mano04062
Chemokine signaling pathway
mano04068
FoxO signaling pathway
mano04072
Phospholipase D signaling pathway
mano04150
mTOR signaling pathway
mano04151
PI3K-Akt signaling pathway
mano04510
Focal adhesion
mano04540
Gap junction
mano04630
JAK-STAT signaling pathway
mano04650
Natural killer cell mediated cytotoxicity
mano04660
T cell receptor signaling pathway
mano04662
B cell receptor signaling pathway
mano04664
Fc epsilon RI signaling pathway
mano04714
Thermogenesis
mano04722
Neurotrophin signaling pathway
mano04810
Regulation of actin cytoskeleton
mano04910
Insulin signaling pathway
mano04912
GnRH signaling pathway
mano04915
Estrogen signaling pathway
mano04917
Prolactin signaling pathway
mano04926
Relaxin signaling pathway
mano04935
Growth hormone synthesis, secretion and action
mano05034
Alcoholism
mano05160
Hepatitis C
mano05161
Hepatitis B
mano05163
Human cytomegalovirus infection
mano05165
Human papillomavirus infection
mano05200
Pathways in cancer
mano05205
Proteoglycans in cancer
mano05206
MicroRNAs in cancer
mano05207
Chemical carcinogenesis - receptor activation
mano05208
Chemical carcinogenesis - reactive oxygen species
mano05210
Colorectal cancer
mano05211
Renal cell carcinoma
mano05213
Endometrial cancer
mano05214
Glioma
mano05215
Prostate cancer
mano05220
Chronic myeloid leukemia
mano05221
Acute myeloid leukemia
mano05223
Non-small cell lung cancer
mano05224
Breast cancer
mano05225
Hepatocellular carcinoma
mano05226
Gastric cancer
mano05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mano00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
123851004 (SOS1)
04012 ErbB signaling pathway
123851004 (SOS1)
04014 Ras signaling pathway
123851004 (SOS1)
04630 JAK-STAT signaling pathway
123851004 (SOS1)
04068 FoxO signaling pathway
123851004 (SOS1)
04072 Phospholipase D signaling pathway
123851004 (SOS1)
04151 PI3K-Akt signaling pathway
123851004 (SOS1)
04150 mTOR signaling pathway
123851004 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
123851004 (SOS1)
04540 Gap junction
123851004 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
123851004 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
123851004 (SOS1)
04660 T cell receptor signaling pathway
123851004 (SOS1)
04662 B cell receptor signaling pathway
123851004 (SOS1)
04664 Fc epsilon RI signaling pathway
123851004 (SOS1)
04062 Chemokine signaling pathway
123851004 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
123851004 (SOS1)
04912 GnRH signaling pathway
123851004 (SOS1)
04915 Estrogen signaling pathway
123851004 (SOS1)
04917 Prolactin signaling pathway
123851004 (SOS1)
04926 Relaxin signaling pathway
123851004 (SOS1)
04935 Growth hormone synthesis, secretion and action
123851004 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
123851004 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
123851004 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123851004 (SOS1)
05206 MicroRNAs in cancer
123851004 (SOS1)
05205 Proteoglycans in cancer
123851004 (SOS1)
05207 Chemical carcinogenesis - receptor activation
123851004 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
123851004 (SOS1)
05231 Choline metabolism in cancer
123851004 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
123851004 (SOS1)
05225 Hepatocellular carcinoma
123851004 (SOS1)
05226 Gastric cancer
123851004 (SOS1)
05214 Glioma
123851004 (SOS1)
05221 Acute myeloid leukemia
123851004 (SOS1)
05220 Chronic myeloid leukemia
123851004 (SOS1)
05211 Renal cell carcinoma
123851004 (SOS1)
05215 Prostate cancer
123851004 (SOS1)
05213 Endometrial cancer
123851004 (SOS1)
05224 Breast cancer
123851004 (SOS1)
05223 Non-small cell lung cancer
123851004 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
123851004 (SOS1)
05160 Hepatitis C
123851004 (SOS1)
05163 Human cytomegalovirus infection
123851004 (SOS1)
05165 Human papillomavirus infection
123851004 (SOS1)
09165 Substance dependence
05034 Alcoholism
123851004 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123851004 (SOS1)
01522 Endocrine resistance
123851004 (SOS1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_10
PH_19
IQ_SEC7_PH
RHG20_PH
Takusan
Motif
Other DBs
NCBI-GeneID:
123851004
NCBI-ProteinID:
XP_045740421
LinkDB
All DBs
Position
Unknown
AA seq
1333 aa
AA seq
DB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESSDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSSDTIFIQVSLPHGPRSASVSSISL
TKGTDEVPLPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISD
RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
PQTPSPHGTRRHLPSPPLTQEVDLPSITGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
RDGPPLLENAHSS
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgcagcagctgccgtacgagtttttcagcgaggagaacgcacccaagtggcgg
gggctgctggtgccggcgctgaaaaaggtccaggggcaagttcatccgactcttgagtct
agtgatgatgctcttcaatatgttgaagaattaattttgcagttattaaatatgctatgc
caagctcagccccgaagtgcttcagatgtagaggaacgtgttcaaaaaagtttccctcat
ccaattgataagtgggcaatagctgatgcccaatcggctattgaaaagaggaagcgaaga
aaccctttatctctcccagtagaaaaaattcatcctttactaaaggaggtcctaggttat
aaaattgaccaccaggtttctgtttacatagtagctgtattagaatacatttctgcagac
attttaaagctggtggggaattatgtacgaaatatacggcattatgaaattacaaaacaa
gatattaaagtggcaatgtgtgctgataaggtattaatggacatgtttcatcaagatgta
gaagatataaatatattatctttaactgatgaagagccttccacctcaggagagcaaact
tattatgatttggtaaaagcatttatggcagaaattcgacagtacataagggaactaaat
ttaattataaaagtttttagagagccctttgtctccaactcaaaattgttttcagctaat
gatgtagaaaatatatttagtcgtatagtagatatacatgaacttagtgtaaagttactg
ggccatatagaagatactgtggaaatgactgatgaaggtagcccccatcccttagtagga
agctgctttgaagacttagctgaagaactggcatttgatccatatgaatcatatgctcga
gatattttacggcctggttttcatgatcgcttccttagtcagttatcaaagcctggagcg
gcactctatttacagtcaataggcgaaggtttcaaagaagctgttcagtatgttttaccc
aggctacttctagcccctgtttaccactgtctacattactttgaacttttgaagcagtta
gaagaaaagagtgaagatcaagaagacaaggaatgtttgaaacaagcaattacagctttg
cttaatgttcagagtggtatggaaaaaatatgttctaaaagtcttgcaaaacgaagactg
agtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaactagcaatcaag
aaaatgaacgagattcaaaagaatattgatggttgggagggaaaggacattggacagtgt
tgcaatgaatttataatggaaggaactcttacacgtgtaggagccaaacatgagagacac
atatttctctttgatggcttaatgatttgctgtaaatcaaatcatgggcagccaagactt
cctggtgctagcaatgcagaatatcgtcttaaagaaaagtttttcatgcgaaaggtacaa
attaatgacaaagatgacaccagtgagtacaagcatgcttttgaaataattttaaaagat
gaaaacagtgttatattttctgccaagtcagctgaagagaaaaacaattggatggcagca
ttgatatctttacaataccggagtacactggaaaggatgcttgatgtgacgatgctgcag
gaagagaaggaggagcagatgaggctccctagtgctgatgtttatagatttgcagagcct
gactctgaagagaatataatatttgaagaaaacatgcagcccaaggctggaattccaatt
atcaaagcgggaactgttattaaacttatagagaggctcacgtaccatatgtacgcagat
cccaattttgttcggacatttcttacaacatacagatccttttgtaaacctcaagaacta
ctgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaagctgatcgc
atagctatagagaatggagatcagcccttgagtgcagaactaaaaaggtttagaaaagaa
tacatacagcctgtacagctgcgagtattaaatgtatgtcggcattgggtagagcaccac
ttctatgattttgaaagggatgcagatcttttgcagcgaatggaagaatttattggaaca
gtgagaggtaaagcaatgaaaaaatgggttgaatccatcactaaaataatccaaaggaaa
aaaattgcaagagacaatggaccaggtcataatattacatttcagagttcacctcccaca
gttgagtggcatataagcaggcccgggcacatagagacttttgacctgctcaccttacac
ccaatagaaattgctcgacaactcactttacttgaatcagatctatatcgagctgtacag
ccatcagaattagttggaagtgtgtggacaaaagaagacaaagaaattaattctcctaat
cttctaaaaatgatccggcataccactaatctcactctgtggtttgagaaatgtattgta
gaaactgaaaacttagaagaaagagtagctgtggtgagtcgaataattgagattctacaa
gtctttcaagagctgaacaacttcaatggtgtccttgaggttgtcagtgctatgaactcc
tcacctgtttacagactagaccacacatttgagcaaataccaagtcgccaaaagaaaatt
ttagaagaagctcatgaattaagtgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccatgtgtgcctttctttggaatttatctaactaatatcttgaaaaca
gaagaaggcaaccctgaggtcctaaaaaggcatggaaaagagcttataaactttagcaaa
aggaggaaagtagcagaaataacaggagagatccagcagtaccaaaatcagccttattgt
ttacgagtagaatcagatatcaaaaggttctttgaaaatttgaatccaatgggaaatagc
atggaaaaagaatttacagattatcttttcaacaaatccctagaaatagaaccacgaaat
cctaaacctctcccaagatttccaaaaaaatatagctatcccctaaaatctcctggtgtt
cgtccatcaaacccaagaccaggtaccatgagacatcccacacctctgcagcaggagcca
aggaaaattagttatagtaggatccctgaaagtgaaacagaaagtacggcatctgcacca
aactctccaagaacaccgttaacacctcctcctgcttctggtgcttctagtaccacagat
gtttgcagcgtttttgattccgatcattcgagcccttttcactcaagcagcgataccatc
tttatccaagtttcactgccccatggcccaagatctgcttcagtatcgtctataagttta
accaagggcactgatgaagtgcccctcccccctcctgttcctccacgaagacggccggaa
tctgcccccgccgaatcttcgccgtctaagattatgtctaagcatttggacagcccccca
gcgattcctcctaggcagcccacatccaaagcctattcaccacgatactcaatatcagac
cggacctctatatcagaccctcctgagagccctcccttattaccaccgcgagaacctgtg
aggacacctgatgttttctccagctccccgctacatctccagcctccccctttgggcaaa
aaaagcgatcatggcaatgccttcttcccaaacagcccttccccttttacaccacctcct
cctcaaacaccgtctccccatggcacaagaaggcatctgccgtcgccaccattgacacaa
gaagtggaccttccttccatcactgggccgcctgttcctccacgacaaagcacttctcaa
catatccctaaactccctccaaaaacttataaaagggagcacacgcacccatccatgcac
agagatggaccaccgctgttggagaacgcccactcctcctga
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integrated database retrieval system
