Mirounga angustirostris (Northern elephant seal): 123854035
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Entry
123854035 CDS
T11530
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
mano Mirounga angustirostris (Northern elephant seal)
Pathway
mano01521
EGFR tyrosine kinase inhibitor resistance
mano01522
Endocrine resistance
mano01524
Platinum drug resistance
mano04010
MAPK signaling pathway
mano04012
ErbB signaling pathway
mano04020
Calcium signaling pathway
mano04066
HIF-1 signaling pathway
mano04151
PI3K-Akt signaling pathway
mano04510
Focal adhesion
mano04518
Integrin signaling
mano04520
Adherens junction
mano04530
Tight junction
mano05200
Pathways in cancer
mano05205
Proteoglycans in cancer
mano05206
MicroRNAs in cancer
mano05212
Pancreatic cancer
mano05213
Endometrial cancer
mano05215
Prostate cancer
mano05219
Bladder cancer
mano05223
Non-small cell lung cancer
mano05224
Breast cancer
mano05226
Gastric cancer
mano05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mano00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
123854035 (ERBB2)
04012 ErbB signaling pathway
123854035 (ERBB2)
04066 HIF-1 signaling pathway
123854035 (ERBB2)
04020 Calcium signaling pathway
123854035 (ERBB2)
04151 PI3K-Akt signaling pathway
123854035 (ERBB2)
09133 Signaling molecules and interaction
04518 Integrin signaling
123854035 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
123854035 (ERBB2)
04520 Adherens junction
123854035 (ERBB2)
04530 Tight junction
123854035 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123854035 (ERBB2)
05206 MicroRNAs in cancer
123854035 (ERBB2)
05205 Proteoglycans in cancer
123854035 (ERBB2)
05230 Central carbon metabolism in cancer
123854035 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
123854035 (ERBB2)
05226 Gastric cancer
123854035 (ERBB2)
05219 Bladder cancer
123854035 (ERBB2)
05215 Prostate cancer
123854035 (ERBB2)
05213 Endometrial cancer
123854035 (ERBB2)
05224 Breast cancer
123854035 (ERBB2)
05223 Non-small cell lung cancer
123854035 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123854035 (ERBB2)
01524 Platinum drug resistance
123854035 (ERBB2)
01522 Endocrine resistance
123854035 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mano01001
]
123854035 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mano04147
]
123854035 (ERBB2)
04090 CD molecules [BR:
mano04090
]
123854035 (ERBB2)
Enzymes [BR:
mano01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
123854035 (ERBB2)
Protein kinases [BR:
mano01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
123854035 (ERBB2)
Exosome [BR:
mano04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
123854035 (ERBB2)
CD molecules [BR:
mano04090
]
Proteins
123854035 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
Kinase-like
Bestrophin-like
Motif
Other DBs
NCBI-GeneID:
123854035
NCBI-ProteinID:
XP_045744936
LinkDB
All DBs
Position
Unknown
AA seq
1260 aa
AA seq
DB search
MELAAWCRWGLLLALLPCGAAGTQVCTGTDMKLQLPASPETHLDMLRHLYQACQVVQGNL
ELTYLPANASLSFLQDIQEVQGYVLIAHSQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
EPPEGGASEAGAAPGGLRELQLRSLTEILKGGVLIQRNPQLCHQDTILWKDIFHKNNQLA
LMLIDTNRSRACPPCSPACKDPHCWGASSGDCQSLTRTVCAGGCARCKGPKPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSAN
IQEFAGCKKVFGSLAFLPESFEGDPASNTAPLQPEQLRVFEALEEITGYLYISAWPDSLP
NLSVFQNLRVIRGRVLHDGAYSLTLQELGISWLGLRSLRELGSGLALIHRNARLCFIHTV
PWDQLFRNPHQALLHSANRPEAECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVKDRYCLPCHSECRPQNGSVTCFGAEADQCVACAHYKDPPFCVARC
PSGVKPDLSFMPIWKFADEEGTCQPCPINCTHSCADLDERGCPAEQRASPVTSIIAAVVG
ILLAVVVGLVLGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGPAHHRHRSSSTRSGGGEVTLGLEPSEEEPPKSPLAPSEG
AGSDVFDGDLGMGAAKGLHSLPPQDPSPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYV
NQPEVWPQPPSPLEGPLPPSRPAGATLERPKTLSPKTLSPGKNGVVKDVFAFGSAVENPE
YLAPRGRAAPQPHPPPAFSPAFDNLYYWDQDPSERGSPPSTFEGTPTAENPEYLGLDVPV
NT seq
3783 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccctgcggagcc
gcgggcacccaagtgtgtaccggtacagacatgaagctgcagctcccagccagtcccgag
acgcacctggatatgctccgtcacctctaccaggcctgtcaagtggtgcagggtaacctg
gagctcacctacctgcctgccaatgccagcctgtccttcctgcaggatatccaggaggtg
cagggctacgtgctcattgctcacagccaagtgagacaggtcccgctgcagaggctccga
atcgtgcgaggcacccagctctttgaggacaactacgccctggccgtgctggacaatgga
gagccgcccgaggggggcgcctctgaggcaggggctgccccaggagggctgcgggagctg
cagcttcgaagcctcacagagatcctgaagggaggggtcttgattcagcggaacccacag
ctctgccaccaggacacgattttgtggaaggacatcttccacaagaacaaccagcttgcg
ctcatgctgatagacaccaaccgctctcgggcctgcccaccctgttctccagcttgtaaa
gacccccactgctggggagcaagttccggggactgtcagagcttgacgcgaacggtctgt
gccggaggctgtgcccgctgcaagggcccgaagcccactgactgctgccacgagcagtgt
gcagcgggttgcacaggccccaagcactcggactgcctggcctgccttcacttcaaccac
agtggcatctgtgagctgcactgcccagccctggtcacctacaacacggacaccttcgaa
tccatgcccaaccccgagggccgatacaccttcggggccagctgtgtgaccgcctgtcca
tacaactacctatctacggacgtgggctcctgcaccctggtctgtcccctgaacaaccaa
gaggtgacggctgaggacggaacacagcggtgtgagaaatgcagcaagccctgtgcccga
gtgtgctacggcctgggcatggagcacctgcgggaggtgagggcggtcaccagcgccaac
atccaagagtttgccggctgcaagaaggtctttgggagcctggcgtttctgccagagagc
tttgagggagacccagcctccaacactgcccccctccagcctgagcagctcagagtgttt
gaggctctggaggagatcacaggttacctgtatatctcagcgtggccagacagcctgcct
aacctcagtgtcttccagaacctgcgagtcatccggggacgagttctgcatgacggcgcc
tactcgctgaccctgcaagagctgggcatcagctggctggggctgcgctcactgcgggaa
ctgggcagtgggctggccctcatccaccgcaacgcccgcctctgcttcatacacacggtg
ccctgggaccagctcttccggaacccccaccaggccctgctgcacagtgccaaccggccg
gaggccgagtgcgtgggcgagggcctggcctgctacccgctgtgcgcccatgggcactgc
tggggtccggggcccacccagtgcgtcaactgcagccaattccttcggggccaggagtgc
gtggaggaatgccgagtactgcaggggctaccccgggaatatgtgaaggacaggtactgt
ctgccgtgtcactccgagtgtcggccccagaacggctcagtgacctgctttggggcggag
gctgaccagtgtgtggcctgtgcccactacaaggaccctcccttctgcgtggctcgctgc
cccagtggtgtgaaacccgacctctccttcatgcccatttggaagttcgcagatgaggag
ggcacgtgccagccgtgtcccatcaactgcacccactcctgtgcggacctagacgagagg
ggctgccctgccgagcagagagccagccccgtgacatccatcattgctgctgtggtgggc
attctgctggctgtggtcgtggggctggtcctcggcatcctaatcaagcgaaggcggcag
aagatccggaagtacacgatgcggaggctgctgcaggaaaccgagctggtggagccgctg
acgcctagtggagcgatgcccaaccaggctcagatgcggatcctgaaagagacagagctg
aggaaggtgaaggtgcttggatccggagcttttggcacagtctacaagggcatctggatc
cctgatggggaaaatgtgaaaatcccagtggccatcaaagtgttgagggaaaacacatct
cccaaagccaacaaagaaatcttggatgaagcgtatgtgatggctggcgtgggctcccca
tatgtgtcccgccttctgggcatctgcctgacatccacggtgcagctggtaacacagctc
atgccctacggctgcctcttagaccatgtccgagagcaccgcgggcgcctaggctcccag
gacctgctgaactggtgtgtgcagatcgccaaggggatgagctacttggaggacgttcgg
ctcgtgcacagggacctggctgcccggaacgtgctggtcaagagtcccaaccatgtcaag
attacagacttcgggctggctcggttgctggacattgacgagaccgagtaccacgcggat
gggggcaaggtgcccatcaagtggatggcgctggagtccattctccgccggcggttcacc
caccagagcgatgtgtggagctacggtgtgactgtgtgggaactgatgacttttggggcc
aaaccttacgatgggatcccagcccgggagatccctgacctgctggagaagggggagcgg
ctgccccagccccccatctgtaccattgacgtctacatgatcatggtcaaatgttggatg
atagactccgaatgtcgaccacggttccgggagctggtggccgaattctcccgcatggcc
agggacccccagcgctttgtggttatccagaatgaagacttgggccccgccagcccgttg
gacagcaccttctaccgttcgctgctggaagatgatgacatgggggacctggtggatgct
gaggagtacctggtaccccagcaggggtttttctgtccagaccctgccccaggtgctggg
ggcccggcccaccacaggcaccgcagctcatccaccaggagtggcggtggtgaggtgaca
ctgggactggagccctccgaggaggagccccccaagtctccactggcaccctcagagggg
gctggctctgacgtgtttgatggcgacttgggaatgggggcagccaaggggctgcacagc
ctcccgccacaggaccccagtcctctacagcggtacagcgaggaccctacagtacccctg
ccccctgagactgatggctacgttgcccccctgacctgcagcccccagcctgaatatgtg
aatcagccagaggtttggccgcagcccccctcgcccctagaaggccctctgcctccttct
cgacctgccggtgccactctggaaaggcccaagactttgtcccccaagactctctcccct
ggcaagaatggggttgttaaagacgtttttgcctttgggagtgctgtggagaaccctgag
tacttggcaccccggggcagggctgcccctcagccccaccctcctccagccttcagccca
gcatttgacaacctctattactgggaccaggacccatcagagcggggctctccacccagc
acctttgaagggacccctacagcagaaaaccctgagtacctgggcctggacgtgccagtg
tga
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integrated database retrieval system
