Misgurnus anguillicaudatus (oriental weatherfish): 129415702
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Entry
129415702 CDS
T09481
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
manu
Misgurnus anguillicaudatus (oriental weatherfish)
Pathway
manu00270
Cysteine and methionine metabolism
manu00480
Glutathione metabolism
manu01100
Metabolic pathways
manu01240
Biosynthesis of cofactors
manu04216
Ferroptosis
Module
manu_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
manu00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
129415702 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
129415702 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
129415702 (gclc)
Enzymes [BR:
manu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
129415702 (gclc)
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Motif
Pfam:
GCS
GCS2
mRNA_triPase
Motif
Other DBs
NCBI-GeneID:
129415702
NCBI-ProteinID:
XP_055025769
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All DBs
Position
11:complement(1035739..1062733)
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AA seq
631 aa
AA seq
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MGLLSQGSPLNWDETKKHADHVRKHGILQFLNIYNKVKERQKDVLKWGDEVEYMLVEMDD
KNEKARLVLNGKEVLEILQEKGENINPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMGKRRGEASSVLKKSQTLLTVTSFPRLGCPGFTLPEHKPTPTEKGVSKSLFFPDEAI
NSHPRFSTLTRNIRHRRGEKVVINVPVFKDKNTPSPFVEVFPEDDGEAARAALPDHIYMD
AMGFGMGNCCLQVTFQACSINEARYLYDQLATFCPIVMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTREERGLEPLKINKFRINKSRYDSIDSYLSCCGEKYNDIELTIDEDINKQLL
DAGIDKLLAQHIAHLFIRDPLSLFQEKIHLDDENESDHFENLQSTNWQTMRFKPPPPNSE
IGWRVEFRPMEVQLTDFENSAYVVFIVLLTRVILSYKLDFLIPLSKVDENMKVAQKRNAV
QEGMFYFRTDVFKGCNPVLDPPSTALNGVDGDVNDGDEYTLMSIDTIINGKEGVFQGLIP
MLNSYLENMEVDVDTRCTILNYLKLIKKRASGELMTMAKWMREFVGKHPEYKQDSVITDK
INYDLLRKCDRIAKGEERCPELIGDPVNRAK
NT seq
1896 nt
NT seq
+upstream
nt +downstream
nt
atgggcttgctgtcacaggggtcgccgctcaactgggatgagaccaagaaacatgccgat
cacgttaggaagcacggcatccttcagtttctcaacatctacaataaagtgaaggagcga
cagaaggatgtgctcaagtggggagacgaggtggagtacatgttggtggaaatggatgac
aaaaatgaaaaagcacgcctagttttgaacggaaaggaggttttggaaatccttcaggaa
aaaggagaaaacatcaacccaaatcatcccacattgtggaggccagaatatggaagctat
atgatcgaaggaacccccgggcagccgtacggagggactatgtcagagttcaacacggta
gaggacaacatgggcaagcggagaggagaagcctcatctgtgcttaaaaaaagccaaact
ctcctcacagtcacgtcatttcccaggttaggctgtccaggctttacactgccagagcac
aagccaacacccactgagaaaggagtgtccaaatcgcttttctttcccgacgaggccatt
aacagccatcctagatttagtaccctgacccgaaacatacgccataggaggggtgagaaa
gtggtgataaatgtaccggtttttaaagataaaaacaccccgtccccttttgtggaggtg
tttccagaagatgatggagaggctgcccgggctgctctgcctgatcacatctacatggac
gccatgggctttggcatgggaaactgttgcctgcaggtgacttttcaagcttgcagcatc
aatgaggcacgatacctctatgaccagctggccactttctgtcccatagtgatggctctc
agtgccgcttcacctttttatcgtggctacgtatcggacattgattgccgttggggtgta
atctcagcatcagtagatgaccgaactcgagaggagaggggtctggagccactaaagatc
aacaaattccggatcaataaatcgagatacgattcgattgacagctacctgtcctgctgt
ggagagaaatacaatgatattgagctgacaatagatgaagatatcaacaaacagctcctt
gatgcaggcattgacaaactgctggcacagcacattgctcatctatttattcgagatccc
ttgtcactcttccaagagaagattcatttggatgatgaaaacgaatcagatcattttgag
aatcttcagtcaaccaattggcagacaatgaggttcaagcctccccctccaaactctgag
ataggatggagagtagagtttcgaccaatggaggtccagctgacagattttgagaactct
gcttatgtggttttcattgttcttctcacccgtgtgatcttgtcctataaactggatttc
cttattccattatcaaaggttgatgaaaacatgaaggttgcccagaagcgaaatgctgtg
caggagggcatgttttattttcgtacggatgtctttaaaggctgcaacccagtgttagat
ccaccatccactgctctgaatggagtagatggtgacgttaatgatggagacgagtataca
ctcatgagtatcgacaccatcataaatgggaaggagggagtgtttcagggcctgatacca
atgctaaacagctaccttgagaacatggaggtggatgtagacacacgctgcactatcctc
aattacttgaaactcattaaaaagcgggcttcaggtgaactgatgactatggctaaatgg
atgagagagtttgttggcaaacatcctgagtacaagcaggatagtgtcattacagacaaa
ataaactacgatctgctacgcaagtgtgaccgaatcgcaaagggggaagaaagatgtcca
gaactcatcggagacccagtaaacagggcaaaataa
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