Mycobacterium avium subsp. paratuberculosis MAP4: MAP4_1927
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Entry
MAP4_1927 CDS
T02662
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminop imelate-D-alanyl-D-alanyl ligase murF
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mao
Mycobacterium avium subsp. paratuberculosis MAP4
Pathway
mao00300
Lysine biosynthesis
mao00550
Peptidoglycan biosynthesis
mao01100
Metabolic pathways
mao01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mao00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MAP4_1927
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MAP4_1927
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MAP4_1927
Enzymes [BR:
mao01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MAP4_1927
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AGL36843
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Position
2108247..2109806
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AA seq
519 aa
AA seq
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MIELTVAQIADIVGGTLADITAPDAARRRVTGTVEFDSRAVGPGGLFLALPGARTDGHDH
AEAAVAAGAVAVLAARPVGVPAIVAPPVDAADALAGVLEHDADGSGAAVLAALAKLARAV
AAELVAGGLTIVGITGSSGKTSTKDLVAAVLAPLGEVVAPPGSFNNELGHPWTVLRATAD
TDYLVLEMSARHPGNIAALAEIAPPAVGVVLNVGTAHLGEFGSREAIARTKSELPQAVPA
SGVVVLNVDDPTVAAMAEVTAARVVRVGRAEHTEAGPSDVWAGPVSLDELARPGFTLYHR
HAGGTRQARVQLGVSGDHQVGNALCAAAVALECGATVEQVVAALAGAGPVSRHRMQVSTR
GDGVTVIDDAYNANPDSMRAGLQALAWIARGGAEPGAPARRSWAVLGEMAELGDDAIAEH
DRIGRLAVRLDVSRLVVVGTGRSVSAMHHGAVMEGSWGSADKGAVNVPDAEAALELLRAE
LQPGDVVLVKASNAAGLGALADALARDDREGDSAGGTRR
NT seq
1560 nt
NT seq
+upstream
nt +downstream
nt
atgatcgagctgaccgtcgcccagatcgccgacatcgtcggcggcaccctggccgacatc
accgcaccggacgccgcgcgccggcgcgtcaccggcaccgtcgaattcgactcgcgcgcc
gtcgggcccggcgggttgttcctggcgctgcccggggcgcgcaccgacgggcatgaccac
gcggaggccgcggtggccgccggtgcggtcgccgtgctggccgcccggcccgtcggcgtc
cccgccatcgtcgcgccgccggtggacgccgcggacgcgctggccggggtgctcgagcac
gacgccgacgggtccggtgccgcggtgctggcggcgctggccaagctggcgcgggcggtg
gccgccgagctggtcgccggcgggctgaccatcgtcgggatcaccggatcgtcgggcaag
acgtcgaccaaggacctggtcgcggcggtgctggcgccgctgggtgaggtggtggctccg
cccgggtcgttcaacaacgagctggggcatccctggacggtgctgcgcgccacggccgac
accgactacctggttctcgagatgtcggcacgccaccccggcaacatcgccgcgctcgcc
gaaatcgccccgccggccgtgggggtggtgctcaacgtcggcaccgcacacctgggcgag
ttcggctcgcgggaagccatcgcacgcaccaaatccgaactgccgcaagcggttccagcg
tccggcgtggtggtcctcaacgtcgacgaccccaccgtggcggccatggccgaggtgacc
gcggcccgggtggtcagggtcggccgcgccgagcacaccgaggccggccccagtgacgta
tgggccgggccggtgtcgctggacgagttggcccggccggggttcacgctgtatcaccgc
cacgccggtgggacacgacaggcgcgggtgcaactcggcgtctccggcgaccaccaggtc
ggcaacgcgctgtgcgcggccgcggttgcgctggagtgcggcgcgacggtcgagcaggtg
gtggccgcgctcgccggggcgggcccggtgtcgcggcaccggatgcaggtcagcacccgc
ggcgacggcgtcacggtgatcgacgacgcctacaacgccaatcccgattcgatgcgggcc
gggctgcaggccctggcctggatcgcccgcggcggggcggaaccgggcgccccggcccgg
cgcagctgggcggtgctgggcgagatggccgaactcggcgacgacgcgatcgccgaacat
gatcgcatcggccggctggcggtgcgcttagatgtgtctcgactcgttgtcgtgggaact
gggaggtcggtgagcgccatgcaccacggtgcggtcatggagggttcctggggttcggcc
gacaagggagccgtcaacgtgcccgacgccgaggcggcgcttgagctcttgcgggccgag
ctgcagcccggtgacgtggtgctggtcaaggcatccaacgcggccgggctgggcgcactc
gccgacgcgctggcccgtgacgatcgcgagggcgactcagccggcgggacccgccgatga
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