Mycobacterium avium subsp. paratuberculosis MAP4: MAP4_3558
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Entry
MAP4_3558 CDS
T02662
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mao
Mycobacterium avium subsp. paratuberculosis MAP4
Pathway
mao00290
Valine, leucine and isoleucine biosynthesis
mao00620
Pyruvate metabolism
mao01100
Metabolic pathways
mao01110
Biosynthesis of secondary metabolites
mao01210
2-Oxocarboxylic acid metabolism
mao01230
Biosynthesis of amino acids
Module
mao_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mao00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
MAP4_3558
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MAP4_3558
Enzymes [BR:
mao01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
MAP4_3558
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
AGL38421
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Position
complement(3873592..3875436)
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AA seq
614 aa
AA seq
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MRRSEVPSDIPGAITVTSHPDAFSSSRSIVKPAGPPGPGQPAWNPQRGSSMPVNRYRPFA
EEVEPIRLPDRTWPDKVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEI
EVGFPSASQTDFDFVREIITEGAIPDDVTIQVLTQCRPELIERTFAACQGAPQAIVHFYN
STSILQRRVVFRADRAAVQEIAVAGARKCVEEAAKYPETQWRFEYSPESYTGTELEYAKQ
VCDAVGEIIRPTTENPIIFNLPATVEMATPNVYADSIEWMSRNLARRDSVILSLHPHNDR
GTAVAAAELGYAAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRR
TVEYCNQLPVHERHPYGGDLVYTAFSGSHQDAINKGLDQMKIDADAADTDVEDMLWQVPY
LPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKADHGLALPRRLQIEFSQVIQKISEGEGG
EVSPKEMWDAFFEEYLAPVWPLERVKQRVDASDEDSGVTSISATVKINGEQTEINGTGNG
PLAAFVHALAGVGFDVAVLDYSEHAMSSGDDAQAAAYVEASVNGRTVWGVGIAPSITTAS
LRAVVSAVNRAARA
NT seq
1845 nt
NT seq
+upstream
nt +downstream
nt
atgcgccggtctgaggttccttctgatatccccggagcaatcaccgtgacttcccatccc
gacgccttcagctcgtcccgcagcatcgtcaaacccgccggcccgcccggccccggacag
cccgcctggaacccccagcgcggctcctcgatgccggtcaaccggtaccggccgttcgcc
gaggaggtcgagcccatccggctgcccgaccgcacctggcccgacaaggtcatcgaccgt
gccccgctgtggtgcgcggtggacctgcgcgacggcaaccaggcgctgatcgacccgatg
agcccggcccgcaagcgccgcatgttcgacctgctggtccgcatgggctacaaggagatc
gaggtcggcttcccgtcggccagccagaccgatttcgacttcgtccgcgagatcatcacc
gagggcgccattcccgacgacgtcaccattcaggtgctgacccagtgccggccggaactg
atcgagcgcaccttcgccgcgtgccagggcgcgccgcaggccatcgtgcacttctacaac
tcgacgtcaatcctgcagcggcgcgtggtatttcgcgccgaccgggccgcggtgcaggag
atcgccgtggccggcgcccgcaagtgcgtcgaggaggccgccaagtaccccgagacgcag
tggcggttcgagtactcgccggagtcctacaccggaaccgaactggagtacgccaagcag
gtgtgcgacgcggtcggcgaaatcataaggcccacaacggaaaacccgatcatcttcaac
ctgcccgccacggtggagatggccacccccaacgtgtacgccgactccatcgagtggatg
agccgcaatctggcccgccgcgactccgtcatcctgagcctgcacccgcacaacgaccgc
ggaaccgccgtcgccgcagcggaattgggctatgcggccggcgccgaccggatcgagggc
tgcctgttcggcaacggcgaacgcaccggcaacgtgtgcctggtgacgctggggctgaac
ctgttctcccgcggcgtggacccgcagatcgacttctccaacatcgacgagatccgccgc
acggtggagtactgcaatcagctgccggtgcacgagcggcacccctacggcggcgacctg
gtctacaccgcgttctccggcagccaccaggacgccatcaacaagggcctggaccagatg
aagatcgacgccgacgccgccgacaccgacgtcgaggacatgctctggcaggtgccgtat
ctgccgatcgaccccaaggacgtcgggcgcacctacgaggcggtgatccgggtgaactcg
cagtccggcaagggcggggtggcctacatcatgaaggccgatcacggcctggccctgccg
cgccggctgcagatcgagttctcccaggtgatccagaagatcagcgagggcgagggcggc
gaggtcagccccaaggagatgtgggacgcgttcttcgaggagtacctggccccggtgtgg
ccgctggagcgggtcaagcagcgcgtcgacgcctccgacgaggacagcggcgtcaccagc
atctccgcgacggtcaagatcaacggggagcagaccgagatcaacgggaccggcaacggc
ccgctggccgcgttcgtgcacgcgctcgccggggtcgggttcgacgtggcggtgctggac
tactccgagcacgccatgagttcgggcgacgacgcgcaggccgccgcgtatgtggaggcg
tcggtcaacggtcggacggtgtggggtgtcggcatcgccccgtccatcaccaccgcctcg
ttgcgcgcggtggtgtcggcggtcaaccgcgccgcccgcgcctga
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